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Class 514/2 - Peptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter which contains a protein or its reaction
No. of applications: 2930
Last issue date: 10/28/2010


1                      
Application No.Application TitleIssue Date
20100272681Inhibitors of Serine Proteases
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The...
10/28/2010
20100272712JNK3 AS A TARGET FOR THE TREATMENT OF ANGIOGENESIS-RELATED DISEASES
Provided herein are methods for treating a subject having or at risk for an angiogenesis-related disorder. The methods include administering to the subject a therapeutically effective amount of an agent that inhibits JNK3 expression, or a therapeutically effective amoun...
10/28/2010
20100256046TREATMENT OF PROLIFERATIVE DISORDERS
Inhibitors of cIAP-1 and methods and compositions for treating proliferative disorders....
10/07/2010
20100247472AMINATED POLYMERS AND THEIR USE IN WATER-BORNE COMPOSITIONS
The present invention relates to processes for the manufacture of aminated or functionalized aminated polymers and their use in water-borne compositions. More specifically, this invention relates to personal care compositions containing aminated polymers and one or more...
09/30/2010
20100247693COSMETIC FORMULATION TO TREAT ROSACEA TELANGIECTASIA
The present invention features novel cosmetic skin care compositions for improving the appearance of rosacea-affected skin....
09/30/2010
20100240575ANTI-OBESE IMMUNOGENIC HYBRID POLYPEPTIDES AND ANTI-OBESE VACCINE COMPOSITION COMPRISING THE SAME
Disclosed is an immunogenic hybrid polypeptide comprising a mimetic peptide of a B cell epitope of apolipoprotein B-100 and helper T cell epitope, the mimetic peptide being fused at its C-terminus to an N-terminus of the helper T cell epitope. Also disclosed is a vaccin...
09/23/2010
20100239566ENIGMA-MDM2 INTERACTION AND USES THEREOF
The present invention relates to Enigma (PDLIM7)-Mdm2 interaction and use thereof. More particularly, it may induce an effective apoptosis of cancer cells by inhibition of an Enigma expression or an Enigma activity which induces Mdm2 destabilization and p53 activity; it...
09/23/2010
20100240576ANTICONVULSANT COMBINATION THERAPY
The present invention is directed to a pharmaceutical composition comprising a Compound (a) of a class of peptide Compounds and at least one further Compound (b) for the prevention, alleviation or/and treatment of epileptic seizures....
09/23/2010
20100234292METHODS OF ASSESSING A PROPENSITY OF CLINICAL OUTCOME FOR A FEMALE MAMMAL SUFFERING FROM BREAST CANCER
The present invention relates to a method of assessing a propensity of clinical outcome for a female mammal suffering from breast cancer in view of the expression of specific nucleic acid sequences in a biological sample....
09/16/2010
20100234272Processes for Preparing a Polypeptide
The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer...
09/16/2010
20100233277BIODEGRADABLE POLYMER SCAFFOLD AND PROCESS FOR PREPARATION THEREOF
The present invention relates to a process for preparation of a biodegradable polymer scaffold using biodegradable polymer, surfactant and alcohol. The biodegradable polymer scaffold obtained from the process disclosed is useful for tissue engineering, therapeutic compo...
09/16/2010
20100233246ADHESIVE TISSUE REPAIR PATCH AND COLLAGEN SHEETS
The present invention relates generally to synthetic polymer compositions that form interpenetrating polymer networks. In a preferred embodiment, the compositions comprise two multifunctionally activated synthetic polymers, along with a tensile strength enhancer. Such c...
09/16/2010
20100233242ENGINEERED PROTEINS, AND METHODS OF MAKING AND USING
The present invention provides engineered proteins and biomedical products made from the engineered proteins. The biomedical products include lenses useful for ophthalmic purposes....
09/16/2010
20100233295AQUEOUS MOISTURIZERS AND LUBRICANTS AND USES THEREOF
This application relates to water-based personal moisturizers and lubricants that relive vaginal dryness. These compositions are non-spermicidal, sperm- and egg-friendly, and in various embodiments may mimic biological fluids, enhance sperm survival and motility, promot...
09/16/2010
20100234287Targeting Bacterial Suicide Pathways for the Development of Novel Antibiotics
The invention provides methods for identifying an agent which prevents or partially prevents an antitoxin from forming a complex with its cognate toxin, comprising contacting a potential agent with a labeled substrate in solution, whereby detection of the label indicate...
09/16/2010
20100235931Novel Neurological Function of mPKCI
Wildtype and mice lacking the gene encoding PKCI/HINT 1 (PKC−/−) were used to assess the involvement of PKCI/HINT1 in regulating basal locomotor activity and the behavioral activating effects of the psychostimulant, amphetamine. PKCl−/− mic...
09/16/2010
20100227791Compounds Having Antitumor Activity
Disclosed is the use of compounds of formula (I)

wherein X, Y and Z are as defined in the description of the invention, for the preparation of an antitumor medicament, optionally in combination with different...

09/09/2010
20100227792PHOSPHOLIPID AND PROTEIN TABLETS
A new method for krill meal production has been developed using a two step cooking process. In the first step the proteins and phospholipids are removed from the krill and precipitated as a coagulum. In the second stage the krill without phospholipids are cooked. Follow...
09/09/2010
20100227793Compositions and Methods for Treating Amyotrophic Lateral Sclerosis
The invention relates to methods for preserving fast axonal transport in a cell affected by Amyotrophic Lateral Sclerosis by inhibiting pathogenic superoxide dismutase-induced increases in p38α activity. The present invention also provides methods for identifying agent...
09/09/2010
20100227005METHODS TO TREAT AND/OR PREVENT MUCOSITIS
The present invention relates to methods useful for treating and/or preventing mucositis using an active vitamin D compound....
09/09/2010
20100226878METHODS OF INHIBITING PHOTORECEPTOR APOPTOSIS
The present invention provides methods to prevent photoreceptor death. In particular, the present invention provides peptides which prevent FAS-mediated photoreceptor apoptosis....
09/09/2010
20100226960Natural biodegradable matrices and uses thereof
Matrices formed from a natural biodegradable material and that exhibit surface degradation in the presence of an enzyme are described. Matrices including a bioactive agent can be implanted or formed in a subject for release of the bioactive agent upon degradation of the...
09/09/2010
20100227794SMART CONTRAST AGENT AND METHOD FOR DETECTING TRANSITION METAL IONS AND TREATING RELATED DISORDERS
The present disclosure provides smart contrast agents for transition metals and a method of using the same. The smart contrast agents include a core peptide and a first labeling group attached to a first end of the core peptide. The smart contrast agents can also includ...
09/09/2010
20100226990Method of Producing Porous Microparticles
A method of preparing porous microparticles comprises the steps of combining one or more organic compounds with a volatile system, and drying the system thus formed to provide substantially pure porous microparticles of the organic compound or composite porous micropart...
09/09/2010
20100227811FARNESYLAMINE DERIVATIVES AND METHODS OF USE
The present invention concerns farnesylamine derivatives, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of ras-mediated signal transduction and inhibitors of aberrant cell growth, e.g., as anti-cancer agents...
09/09/2010
20100221266METHODS TO REGULATE MIRNA PROCESSING BY TARGETING LIN-28
The present invention relates generally to methods to regulate microRNA (miRNA) biogenesis, in particular the regulation of the processing of pri-miRNA to mature miRNA by Lin-28 and/or variants such as Lin28B. In particular, the present invention relates to methods and ...
09/02/2010
20100221287Streptococcus pneumoniae Polynucleotides and Sequences
The present invention provides polynucleotide sequences of the genome of Streptococcus pneumoniae, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and...
09/02/2010
20100221308ANTIMICROBIAL COMPOSITIONS AND USES THEREOF
The present invention includes compositions for preventing growth and proliferation of biofilm embedded microorganisms comprising: (a) a cationic polypeptide and (b) a bis-gaunide or a salt thereof. The invention further provides methods for preparing objects with such ...
09/02/2010
20100222875METHOD FOR FORMING A POROUS STENT COATING
Methods for forming porous stent coatings are disclosed....
09/02/2010
20100221247AGENTS AND METHODS FOR TREATMENT OF CANCER
The present application describes compositions that are useful for the treatment, prevention and/or amelioration of cancer....
09/02/2010
20100222281DELIVERY OF HYDROPHILIC DRUGS
Compositions comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy of the human or animal body are provided. Methods of medical treatment, wherein a composition according to the invention is administered to a human or ani...
09/02/2010
20100221372WOLFBERRIES AND SKIN INFLAMMATION
The present invention relates in general to the field of inflammation. In particular the present invention relates to the use of natural compounds for the preparation of a product to treat or prevent inflammation. For example an extract of wolfberry was shown to have an...
09/02/2010
20100221343COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING
The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrof...
09/02/2010
20100222250POLY-BETA-PEPTIDES FROM FUNCTIONALIZED BETA-LACTAM MONOMERS AND ANTIBACTERIAL COMPOSITIONS CONTAINING SAME
Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed a...
09/02/2010
20100221224COMPOSITION AND METHOD FOR SELF-ASSEMBLY AND MINERALIZATION OF PEPTIDE-AMPHIPHILES
The present invention is directed to a composition useful for making homogeneously mineralized self assembled peptide-amphiphile nanofibers and nanofiber gels. The composition is generally a solution comprised of a positively or negatively charged peptide-amphiphile and...
09/02/2010
20100215731METHOD FOR IMPROVING CARTILAGE REPAIR AND/OR PREVENTING CARTILAGE DEGENERATION IN A JOINT
The invention is in the field of methods for medical treatment. It provides an improved method for repairing damaged cartilage and/or preventing cartilage degeneration in tissue, in particular in a joint by administering a pharmaceutically active agent directly into the...
08/26/2010
20100215728Skincare Methods
Disclosed are compositions and methods for skincare, e.g., reducing skin wrinkles and for treating skin disorders....
08/26/2010
20100215749TEMPERATURE- AND pH-RESPONSIVE POLYMER COMPOSITIONS
Temperature- and pH-responsive copolymer compositions, and drug delivery devices, conjugates, nanoparticles, and micelles that include the compositions....
08/26/2010
20100216688PEPTIDOMIMETIC MACROCYCLES
The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provide...
08/26/2010
20100215724Microcapsule Nanotube Devices for Targeted Delivery of Therapeutic Molecules
A nanotube device comprises a gel matrix that includes microcapsules and functionalized nanotubes, or other functionalized nanostructures incorporated into said gel matrix. Pharmaceutical compositions and methods of treatment comprising same. The pharmaceutical composit...
08/26/2010
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