In 1608, Dutch eyeglass maker Hans Lipperhey filed the first patent for a working telescope. The patent was denied.
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| Application No. | Application Title | Issue Date |
| 20120071456 | COMPOSITION Hair treatment composition comprising a zinc-based antidandruff agent, a conazole fungicide and a cationic modified guar deposition polymer.... | 03/22/2012 |
| 20120010075 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER The present invention relates to the use of mixtures containing hydrazone compounds and copper for controlling the growth of fungi.... | 01/12/2012 |
| 20110306585 | Metal Complexes of N-Heterocyclic Carbenes The present invention generally relates to metal complexes of N-heterocyclic carbenes that contain one or more additional active moieties and/or groups therein. In one embodiment, the present invention relates to metal complexes of N-heterocyclic carbenes that contain a... | 12/15/2011 |
| 20110305778 | Chemically Stabilized Anti-Dandruff Compositions For Use In Personal Care Compositions The present invention is directed to a stabilized anti-dandruff composition comprising about 10 wt. % to about 40 wt. % of an insoluble anti-dandruff agent, about 6 wt. % to about 12 wt. % of a stabilizer, less than about 1 wt. % of a preservative, and about 0.5 wt. % t... | 12/15/2011 |
| 20110305636 | COMPOUNDS, COMPOSITIONS, METHODS OF SYNTHESIS, AND METHODS OF TREATMENT Briefly described, embodiments of this disclosure include compounds as described herein, labeled compounds as described herein, pharmaceutical composition including compounds described herein, methods of imaging, method of forming a compound as described herein, and the... | 12/15/2011 |
| 20110236471 | PLATINUM COMPLEXES AND METHODS FOR INHIBITING TUMOR CELL PROLIFERATION The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the... | 09/29/2011 |
| 20110230456 | Nitridoosmium(VI) Complexes for Treatment of Cancer The invention relates to nitridoosmium complexes and methods of using these compounds as treatments for cancer.... | 09/22/2011 |
| 20110172199 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF The invention relates to the platinum N-heterocycle derivatives of general formula (I) in which—R1 and/or R2 are, independently of one another, an aryl or aralkyl group, each optionall... | 07/14/2011 |
| 20110142829 | ANTI-TUMOUR COMPOSITIONS AND METHODS A method for the prophylaxis and/or treatment of a tumour in a subject is provided. The method comprises the steps of administering a therapeutically effective amount of a composition comprising an anti-tumour agent and a therapeutically effective amount of a compositio... | 06/16/2011 |
| 20110104103 | Method of conjugating therapeutic compounds to cell targeting devices via metal complexes The present invention relates to a cell-targeting complex comprising a targeting moiety and a deliverable compound, wherein said targeting moiety and said deliverable compound are joined by means of a (transition) metal ion complex having at least a first reactive moiet... | 05/05/2011 |
| 20110086830 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES The present invention generally relates to metal complexes of N-heterocyclic carbenes that contain one or more additional active moieties and/or groups therein. In one embodiment, the present invention relates to metal complexes of N-heterocyclic carbenes that contain a... | 04/14/2011 |
| 20110021485 | INDOLE DERIVATIVES AND THEIR METAL CONJUGATES AND USES THEREOF Provided are compounds which are indole derivatives, as well as pharmaceutical compositions containing the compounds. Also provided are methods of using the indole compounds for preventing or treating a disease, or a condition that predisposes to a disease, wherein the ... | 01/27/2011 |
| 20110009376 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR EYE DISEASE ACCOMPANIED BY OPTIC NERVE DISORDER The present invention provides a novel pharmaceutical use of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof. 2-Phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof exhibits an excellent suppressive effect on retinal ganglion cell death in a pharmacological... | 01/13/2011 |
| 20100316704 | PLATINUM COMPLEXES AND METHODS OF USE The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the... | 12/16/2010 |
| 20100310599 | Orally Bioavailable Lipid-Based Constructs The present invention is embodied by a composition capable inducing weight loss in a patient in need thereof.... | 12/09/2010 |
| 20100305084 | BICYCLIC INDOLE-PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE Formula I (Ia and Ib) compounds wherein (i) X1 is N and X2 is S, (ii) X1 is CR7 and X2 is S, (iii) X1 is N and X2 is NR2, (iv) X1 is CR7 and X2 is O,... | 12/02/2010 |
| 20100292202 | FUNGICIDAL COMPOSITIONS FOR TURF TREATMENT AND IMPROVEMENT The present invention relates to novel compositions comprising a fungicide that inhibits mitochondrial respiration at the QoI site, (QoI inhibitor), a contact fungicide, a demethylation inhibitor and pigments, which are highly suitable for controlling unwanted phytopath... | 11/18/2010 |
| 20100272829 | COMPOSITION FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION It is required to devise a way to reduce the amount of zinc pyrithione added to hair care products as an anti-dandruff agent so as to decrease stimulation to the ocular mucosa, and to reduce an influence on the environment of domestic wastewater, and a way to accelerate... | 10/28/2010 |
| 20100273763 | ORGANOMETALLIC COMPLEXES AS THERAPEUTIC AGENTS This invention comprises salophene-based metallic complexes. Included are metal-chelating analogues, and method of their preparation and use. These analogues have therapeutic activity including anticancer activity.... | 10/28/2010 |
| 20100239522 | CHEMOTHERAPEUTIC FOR INDUCING AN MSH2-DEPENDENT APOPTOTIC PATHWAY A method of treating cancer in a subject in need thereof comprises administering said subject reserpine, yohimbine, an analog thereof, or a pharmaceutically acceptable salt or prodrug thereof, in an amount effective to treat the cancer. Compounds and compositions useful... | 09/23/2010 |
| 20100233166 | NOVEL IDO INHIBITORS AND METHODS OF USE Compounds, compositions and methods for the treatment of malignancy are disclosed.... | 09/16/2010 |
| 20100221211 | PYRIDONE-SUBSTITUTED-DIHYDROPYRAZOLOPYRIMIDINONE DERIVATIVE The invention relates to a compound of general formula (I-0): wherein R1 means a C1-C6 alkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group, or a C3-C6 cycloalkyl group; R2, R3... | 09/02/2010 |
| 20100215773 | Use of Quinazoline Derivative ZD6474 Combined With Platinum Compounds and Optionally Ionising Radiation in the Treatment of Diseases Associated With Angiogenesis and/or Increased Vascular Permeability The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of ... | 08/26/2010 |
| 20100210616 | METAL COMPLEXES INCORPORATED WITHIN BIODEGRADABLE NANOPARTICLES AND THEIR USE Compounds for antimicrobial applications, and for treating bacterial and fungal infection are set forth. The compounds may include a metal complex incorporated into a biodegradable polymeric nanoparticle. Also, a method of treating bacterial and fungal infections in a m... | 08/19/2010 |
| 20100189811 | Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone The invention relates to a biocide composition comprising, as active microbicidal components, 2-methylisothiazolin-3-one and also one or more haloalkyl sulphones, said composition being outstandingly suitable as an industrial preservative for protecting industrial produ... | 07/29/2010 |
| 20100183688 | Delivery System and Method of Manufacturing the Same A microparticle delivery system for an active compound which includes an active compound loaded onto polymeric microparticles, wherein the loaded microparticles are encased by a matrix material comprising about 68% to about 99%, by weight, of the microparticle delivery ... | 07/22/2010 |
| 20100173121 | Method and Treatment Composition for Imparting Durable Antimicrobial Properties to Carpet Methods and treatment compositions for imparting durable antimicrobial properties to carpet are provided. The method includes applying a composition comprising a first antimicrobial compound and a fluoropolymer to the carpet substrate. The carpet substrate may be steame... | 07/08/2010 |
| 20100160268 | Isoflavonoid Analogs and their Metal Conjugates as Anti-Cancer Agents A pharmacologic agent for treating and/or preventing cancer, among other diseases and conditions, and particularly breast, prostate, and pancreatic cancer, in humans and animals. The novel pharmacologic agent is an isoflavonoid or isoflavonoid mimetic covalently attache... | 06/24/2010 |
| 20100144693 | METHOD OF TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) The present invention relates generally to the field of treatment and prophylaxis of retinal degenerative diseases. More particularly, the present invention contemplates a method for preventing, reducing the risk of development of, or otherwise treating or ameliorating ... | 06/10/2010 |
| 20100137272 | Zinc Salt Of Isothiazolone Compound, Method For Reducing Irritation Caused By Isothiazolone Compound, Antibacterial and Antifungal Method Using Zinc Salt of Isothiazolone Compound, and Antibacterial and Antifungal Composition There are provided, according to the present invention, a zinc salt of an isothiazolone compound represented by the following formula (1); a method for reducing the extent of irritation by converting the isothiazolone compound represented by the formula (1) into a zinc ... | 06/03/2010 |
| 20100075940 | DENDRITIC POLYAMIDOAMINE PHTHALOCYANINE DERIVATIVE The present invention is directed to a dendritic polyamidoamine phthalocyanine derivative which is useful as, for example, a fluorescent material or a photodynamic therapeutic drug for cancer. The derivative is represented by the following formula (1): 03/25/2010 | |
| 20100075939 | Immobilized 1,2-benzisothiazolin-3-one The present invention provides novel antimicrobial immobilized 1,2-benzisothiazolin-3-one/zinc oxide (BIT/ZnO) complexes useful as antimicrobial agents because of their resistance to being leached from the substrate to which they are attached. The present invention is a... | 03/25/2010 |
| 20100062087 | Nutraceutical Treatments for Diabetic and Non-Diabetic Wound Healing In an embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce in... | 03/11/2010 |
| 20090318402 | RUTHENIUM (II) COMPOUNDS A ruthenium (II) compound of formula (I) wherein X is halo or a neutral or negatively charged O, N- or S-donor ligand; Y is a counterion; m is 0 or 1; q is 1, 2 or 3; A is either: (i) (Ru)—NRN1RN2—RN3—(N), whe... | 12/24/2009 |
| 20090285884 | Platinum Complexes and Methods of Use The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the... | 11/19/2009 |
| 20090233893 | Methods of Dissolving Beta-Sheet Proteins and Uses Thereof The application discloses metallized chelator complexes and uses of metallized chelator complexes for dissolving β-sheet proteins and reducing formation of β-sheet proteins, where the metallized chelator complex comprises a metal ion chelator and a metal ion.... | 09/17/2009 |
| 20090214626 | Platinum Complexes For Targeted Drug Delivery The subject invention concerns biotin-conjugated platinum complexes that exhibit direct and indirect (immunological) antitumor cell activity. The subject invention also concerns the biotin-platinum complexes of the invention that have another molecule, such as an antibo... | 08/27/2009 |
| 20090169644 | Antidandruff Shampoo Surfactant-containing cleansing compositions contain hydrogenated castor oil for stabilizing an antidandruff component that is insoluble in the cleansing composition. As a result, thorough and gentle cleansing of skin and/or of hair with simultaneous antidandruff effect... | 07/02/2009 |
| 20090169479 | Compounds Comprising Short Aminoalcohol Chains and Metal Complexes for Medical Imgaing The present invention relates to a compound of formula (II) chosen from (IIa) and (IIb) or of formula (VI) chosen from (VIa) and (VIb) of following general formulae: in which: | |
| 20090143338 | Metal coordinated compositions A metal coordination complex of a biologically active moiety and a metal is disclosed. The complex confers to the biologically active moiety an improved performance which can include potency, stability, absorbability, targeted delivery, and combinations thereof.... | 06/04/2009 |