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Class 514/186 - Bicyclo ring system


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the polycyclo system comprises only
No. of applications: 54
Last issue date: 03/22/2012


1    
Application No.Application TitleIssue Date
20120071456COMPOSITION
Hair treatment composition comprising a zinc-based antidandruff agent, a conazole fungicide and a cationic modified guar deposition polymer....
03/22/2012
20120010075SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER
The present invention relates to the use of mixtures containing hydrazone compounds and copper for controlling the growth of fungi....
01/12/2012
20110306585Metal Complexes of N-Heterocyclic Carbenes
The present invention generally relates to metal complexes of N-heterocyclic carbenes that contain one or more additional active moieties and/or groups therein. In one embodiment, the present invention relates to metal complexes of N-heterocyclic carbenes that contain a...
12/15/2011
20110305778Chemically Stabilized Anti-Dandruff Compositions For Use In Personal Care Compositions
The present invention is directed to a stabilized anti-dandruff composition comprising about 10 wt. % to about 40 wt. % of an insoluble anti-dandruff agent, about 6 wt. % to about 12 wt. % of a stabilizer, less than about 1 wt. % of a preservative, and about 0.5 wt. % t...
12/15/2011
20110305636COMPOUNDS, COMPOSITIONS, METHODS OF SYNTHESIS, AND METHODS OF TREATMENT
Briefly described, embodiments of this disclosure include compounds as described herein, labeled compounds as described herein, pharmaceutical composition including compounds described herein, methods of imaging, method of forming a compound as described herein, and the...
12/15/2011
20110236471PLATINUM COMPLEXES AND METHODS FOR INHIBITING TUMOR CELL PROLIFERATION
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the...
09/29/2011
20110230456Nitridoosmium(VI) Complexes for Treatment of Cancer
The invention relates to nitridoosmium complexes and methods of using these compounds as treatments for cancer....
09/22/2011
20110172199PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
The invention relates to the platinum N-heterocycle derivatives of general formula (I)

in which—R1 and/or R2 are, independently of one another, an aryl or aralkyl group, each optionall...

07/14/2011
20110142829ANTI-TUMOUR COMPOSITIONS AND METHODS
A method for the prophylaxis and/or treatment of a tumour in a subject is provided. The method comprises the steps of administering a therapeutically effective amount of a composition comprising an anti-tumour agent and a therapeutically effective amount of a compositio...
06/16/2011
20110104103Method of conjugating therapeutic compounds to cell targeting devices via metal complexes
The present invention relates to a cell-targeting complex comprising a targeting moiety and a deliverable compound, wherein said targeting moiety and said deliverable compound are joined by means of a (transition) metal ion complex having at least a first reactive moiet...
05/05/2011
20110086830METAL COMPLEXES OF N-HETEROCYCLIC CARBENES
The present invention generally relates to metal complexes of N-heterocyclic carbenes that contain one or more additional active moieties and/or groups therein. In one embodiment, the present invention relates to metal complexes of N-heterocyclic carbenes that contain a...
04/14/2011
20110021485INDOLE DERIVATIVES AND THEIR METAL CONJUGATES AND USES THEREOF
Provided are compounds which are indole derivatives, as well as pharmaceutical compositions containing the compounds. Also provided are methods of using the indole compounds for preventing or treating a disease, or a condition that predisposes to a disease, wherein the ...
01/27/2011
20110009376PROPHYLACTIC OR THERAPEUTIC AGENT FOR EYE DISEASE ACCOMPANIED BY OPTIC NERVE DISORDER
The present invention provides a novel pharmaceutical use of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof. 2-Phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof exhibits an excellent suppressive effect on retinal ganglion cell death in a pharmacological...
01/13/2011
20100316704PLATINUM COMPLEXES AND METHODS OF USE
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the...
12/16/2010
20100310599Orally Bioavailable Lipid-Based Constructs
The present invention is embodied by a composition capable inducing weight loss in a patient in need thereof....
12/09/2010
20100305084BICYCLIC INDOLE-PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE
Formula I (Ia and Ib) compounds wherein (i) X1 is N and X2 is S, (ii) X1 is CR7 and X2 is S, (iii) X1 is N and X2 is NR2, (iv) X1 is CR7 and X2 is O,...
12/02/2010
20100292202FUNGICIDAL COMPOSITIONS FOR TURF TREATMENT AND IMPROVEMENT
The present invention relates to novel compositions comprising a fungicide that inhibits mitochondrial respiration at the QoI site, (QoI inhibitor), a contact fungicide, a demethylation inhibitor and pigments, which are highly suitable for controlling unwanted phytopath...
11/18/2010
20100272829COMPOSITION FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION
It is required to devise a way to reduce the amount of zinc pyrithione added to hair care products as an anti-dandruff agent so as to decrease stimulation to the ocular mucosa, and to reduce an influence on the environment of domestic wastewater, and a way to accelerate...
10/28/2010
20100273763ORGANOMETALLIC COMPLEXES AS THERAPEUTIC AGENTS
This invention comprises salophene-based metallic complexes. Included are metal-chelating analogues, and method of their preparation and use. These analogues have therapeutic activity including anticancer activity....
10/28/2010
20100239522CHEMOTHERAPEUTIC FOR INDUCING AN MSH2-DEPENDENT APOPTOTIC PATHWAY
A method of treating cancer in a subject in need thereof comprises administering said subject reserpine, yohimbine, an analog thereof, or a pharmaceutically acceptable salt or prodrug thereof, in an amount effective to treat the cancer. Compounds and compositions useful...
09/23/2010
20100233166NOVEL IDO INHIBITORS AND METHODS OF USE
Compounds, compositions and methods for the treatment of malignancy are disclosed....
09/16/2010
20100221211PYRIDONE-SUBSTITUTED-DIHYDROPYRAZOLOPYRIMIDINONE DERIVATIVE
The invention relates to a compound of general formula (I-0):

wherein R1 means a C1-C6 alkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group, or a C3-C6 cycloalkyl group; R2, R3...

09/02/2010
20100215773Use of Quinazoline Derivative ZD6474 Combined With Platinum Compounds and Optionally Ionising Radiation in the Treatment of Diseases Associated With Angiogenesis and/or Increased Vascular Permeability
The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of ...
08/26/2010
20100210616METAL COMPLEXES INCORPORATED WITHIN BIODEGRADABLE NANOPARTICLES AND THEIR USE
Compounds for antimicrobial applications, and for treating bacterial and fungal infection are set forth. The compounds may include a metal complex incorporated into a biodegradable polymeric nanoparticle. Also, a method of treating bacterial and fungal infections in a m...
08/19/2010
20100189811Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone
The invention relates to a biocide composition comprising, as active microbicidal components, 2-methylisothiazolin-3-one and also one or more haloalkyl sulphones, said composition being outstandingly suitable as an industrial preservative for protecting industrial produ...
07/29/2010
20100183688Delivery System and Method of Manufacturing the Same
A microparticle delivery system for an active compound which includes an active compound loaded onto polymeric microparticles, wherein the loaded microparticles are encased by a matrix material comprising about 68% to about 99%, by weight, of the microparticle delivery ...
07/22/2010
20100173121Method and Treatment Composition for Imparting Durable Antimicrobial Properties to Carpet
Methods and treatment compositions for imparting durable antimicrobial properties to carpet are provided. The method includes applying a composition comprising a first antimicrobial compound and a fluoropolymer to the carpet substrate. The carpet substrate may be steame...
07/08/2010
20100160268Isoflavonoid Analogs and their Metal Conjugates as Anti-Cancer Agents
A pharmacologic agent for treating and/or preventing cancer, among other diseases and conditions, and particularly breast, prostate, and pancreatic cancer, in humans and animals. The novel pharmacologic agent is an isoflavonoid or isoflavonoid mimetic covalently attache...
06/24/2010
20100144693METHOD OF TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD)
The present invention relates generally to the field of treatment and prophylaxis of retinal degenerative diseases. More particularly, the present invention contemplates a method for preventing, reducing the risk of development of, or otherwise treating or ameliorating ...
06/10/2010
20100137272Zinc Salt Of Isothiazolone Compound, Method For Reducing Irritation Caused By Isothiazolone Compound, Antibacterial and Antifungal Method Using Zinc Salt of Isothiazolone Compound, and Antibacterial and Antifungal Composition
There are provided, according to the present invention, a zinc salt of an isothiazolone compound represented by the following formula (1); a method for reducing the extent of irritation by converting the isothiazolone compound represented by the formula (1) into a zinc ...
06/03/2010
20100075940DENDRITIC POLYAMIDOAMINE PHTHALOCYANINE DERIVATIVE
The present invention is directed to a dendritic polyamidoamine phthalocyanine derivative which is useful as, for example, a fluorescent material or a photodynamic therapeutic drug for cancer. The derivative is represented by the following formula (1):

03/25/2010

20100075939Immobilized 1,2-benzisothiazolin-3-one
The present invention provides novel antimicrobial immobilized 1,2-benzisothiazolin-3-one/zinc oxide (BIT/ZnO) complexes useful as antimicrobial agents because of their resistance to being leached from the substrate to which they are attached. The present invention is a...
03/25/2010
20100062087Nutraceutical Treatments for Diabetic and Non-Diabetic Wound Healing
In an embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce in...
03/11/2010
20090318402RUTHENIUM (II) COMPOUNDS
A ruthenium (II) compound of formula (I) wherein X is halo or a neutral or negatively charged O, N- or S-donor ligand; Y is a counterion; m is 0 or 1; q is 1, 2 or 3; A is either: (i) (Ru)—NRN1RN2—RN3(N), whe...
12/24/2009
20090285884Platinum Complexes and Methods of Use
The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the...
11/19/2009
20090233893Methods of Dissolving Beta-Sheet Proteins and Uses Thereof
The application discloses metallized chelator complexes and uses of metallized chelator complexes for dissolving β-sheet proteins and reducing formation of β-sheet proteins, where the metallized chelator complex comprises a metal ion chelator and a metal ion....
09/17/2009
20090214626Platinum Complexes For Targeted Drug Delivery
The subject invention concerns biotin-conjugated platinum complexes that exhibit direct and indirect (immunological) antitumor cell activity. The subject invention also concerns the biotin-platinum complexes of the invention that have another molecule, such as an antibo...
08/27/2009
20090169644Antidandruff Shampoo
Surfactant-containing cleansing compositions contain hydrogenated castor oil for stabilizing an antidandruff component that is insoluble in the cleansing composition. As a result, thorough and gentle cleansing of skin and/or of hair with simultaneous antidandruff effect...
07/02/2009
20090169479Compounds Comprising Short Aminoalcohol Chains and Metal Complexes for Medical Imgaing
The present invention relates to a compound of formula (II) chosen from (IIa) and (IIb) or of formula (VI) chosen from (VIa) and (VIb) of following general formulae:

in which:
X1, X2

07/02/2009
20090143338Metal coordinated compositions
A metal coordination complex of a biologically active moiety and a metal is disclosed. The complex confers to the biologically active moiety an improved performance which can include potency, stability, absorbability, targeted delivery, and combinations thereof....
06/04/2009
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