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| Application No. | Application Title | Issue Date |
| 20120129819 | GEL COMPOSITIONS FOR ADMINISTRATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS The present invention provides a pharmaceutical composition in the form of a water-based gel comprising: at least one pharmaceutically active compound; at least one gelling agent; a solubilising agent; and water, wherein said composition is free or substantially free of... | 05/24/2012 |
| 20120129823 | CONTRACEPTION PROCESS AND ADMINISTRATION FORM FOR THE SAME A method for hormonal contraception comprising administering at least one contraceptive hormone in a plurality of linked taking periods optionally having a sequence lasting several years. Each taking period comprises at least one taking cycle. Each taking cycle comprise... | 05/24/2012 |
| 20120107382 | ARTICLES INCORPORATING ABSORBENT POLYMER AND CERAGENIN COMPOUND An absorbent article includes an absorbent polymer and a ceragenin compound. The ceragenin compound has a sterol group and a plurality of cationic groups that mimic naturally occurring antimicrobial peptides. The ceragenin compound is associated with the absorbent polym... | 05/03/2012 |
| 20120108561 | STORAGE-STABLE, ANTI-MICROBIAL COMPOSITIONS INCLUDING CERAGENIN COMPOUNDS AND METHODS OF USE Storage-stable, anti-microbial compositions and products include a carrier and a ceragenin compound suspended in the carrier. Ceragenin compounds suspended in the carrier include a sterol backbone and a number of cationic groups attached to the sterol backbone via hydro... | 05/03/2012 |
| 20120108560 | SINGLE PHASE SILICONE ACRYLATE FORMULATION This invention provides a single phase silicone acrylate formulation that resists phase separation and includes (A) at least one of a silicone, an acrylate, and combinations thereof. The single phase silicone acrylate formulation also includes (B) a silicone acrylate hy... | 05/03/2012 |
| 20120082659 | Methods And Compositions Related To Synergistic Responses To Oncogenic Mutations Disclosed are compositions and methods related to new targets for cancer treatment.... | 04/05/2012 |
| 20120082715 | Stabilized products, processes and devices for preparing the same A composition comprising a glassified, stabilized particle preparation having a low water activity (between about 0.1 and 0.9) is provided. The preparations provide improved products with enhanced storage stability, less expensive cost of processing, and extended shelf ... | 04/05/2012 |
| 20120083440 | METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting... | 04/05/2012 |
| 20120083481 | FORMULATIONS OF DEOXYCHOLIC ACID AND SALTS THEREOF The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inh... | 04/05/2012 |
| 20120071454 | Steroid Compounds and Treatment Methods The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods and... | 03/22/2012 |
| 20120071455 | 6-SUBSTITUTED DEMETHYL-ESTRADIOL DERIVATIVES AS SELECTIVE ER-BETA AGONISTS Disclosed herein are 6-substituted 13-demethyl-estradiol derivatives as selective ERβ agonists. Also disclosed is a method for treating pain by administering these 6-substituted 13-demethyl-estradiol derivatives.... | 03/22/2012 |
| 20120071453 | STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM A compound with general formula I
| 03/22/2012 |
| 20120070511 | MITOCHONDRIAL INHIBITORS AND USES THEREOF Compositions which modulate mitochondrial functions treat diseases associated with cells that are hyperactively using their endoplasmic reticulum. Screening assays identify agents which modulate mitochondrial functions.... | 03/22/2012 |
| 20120071451 | METHOD OF TREATING NONALCOHOLIC STEATOHEPATITIS WITH ELEVATED DOSES OF URSODEOXYCHOLIC ACID The present invention is directed to a method for the treatment of nonalcoholic steatohepatitis (NASH) by administering an elevated dose of ursodeoxycholic acid (UDCA), or a pharmaceutically acceptable salt thereof, to a patient in need of such treatment, wherein the pa... | 03/22/2012 |
| 20120071539 | COMPOUNDS AND METHODS FOR MODULATING THE SILENCING OF A POLYNUCLEOTIDE OF INTEREST Methods and compositions comprising chemical compounds that modulate the silencing of a polynucleotide of interest in a cell are provided. Such chemical compounds when used in combination with an appropriate silencing element can be used to modulate (increase or decreas... | 03/22/2012 |
| 20120052098 | LIQUID GANAXOLONE FORMULATIONS AND METHODS FOR THE MAKING AND USE THEREOF In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about 50 nm to about 500 nm.... | 03/01/2012 |
| 20120052125 | Cholesteryl Sulfate-Containing Composition As A Haemostatic The present invention relates to a composition comprising a wound dressing device and cholesteryl sulfate and especially to a composition containing cholesteryl sulfate and at least one carrier material for use as a haemostatic agent, as well as to a method for its prep... | 03/01/2012 |
| 20120053163 | Steroids as Agonists for FXR The invention relates to compounds of formula (I):
| 03/01/2012 |
| 20120054920 | Hyperbranched Polycarbonates for Solubilizing Poorly Soluble Active Substances The present invention provides a composition comprising an amphiphile and an active ingredient whose solubility in water at 20° C. is not more than 10 g/L. Likewise provided is an amphiphile comprising a hyperbranched polycarbonate which is joined to at least one linea... | 03/01/2012 |
| 20120046264 | COMMERCIAL SCALE PRODUCTION METHODS FOR TRANSDERMAL HORMONE FORMULATIONS Methods for commercial production of transdermal formulations comprising a hormone compound are provided. In particular, methods for commercial scale production under an inert atmosphere of a transdermal formulation comprising a therapeutically effective amount of a hor... | 02/23/2012 |
| 20120046265 | USE OF ERGOSTA-7,22-DIEN-3beta-OL IN THE TREATMENT OF CANCER A use of an isolated and purified form of ergosta-7,22-dien-3β-ol in the treatment of cancer is provided.... | 02/23/2012 |
| 20120040946 | MEDICINAL FUSIDIC ACID CREAM MADE USING SODIUM FUSIDATE AND INCORPORATING A BIOPOLYMER AND A PROCESS TO MAKE IT The present invention is directed to a medicinal composition for treating bacterial skin infections and related wounds, and also other skin wounds including those caused by burns. The cream also causes skin rejuvenation through an epithelisation process. The cream compr... | 02/16/2012 |
| 20120039805 | Therapeutics And Methods For Treating Neoplastic Diseases Comprising Determining The Level Of Caveolin-1 And/Or Caveolin-2 In A Stromal Cell Sample The invention provides diagnostic and therapeutic methods for neoplastic disease patients with neoplasms of for example, the breast, skin, kidney, lung, pancreas, rectum and colon, prostate, bladder, epithelial, non-epithelial; lymphomas, sarcomas, melanomas, and the li... | 02/16/2012 |
| 20120028944 | CYCLODEXTRIN NANOTECHNOLOGY FOR OPHTHALMIC DRUG DELIVERY The invention provides an ophthalmic composition which is an aqueous suspension comprising drug, cyclodextrin and water, the composition having an aqueous phase of from about 0.1% (w/v) to about 90% (w/v) of the drug in solution, as dissolved free drug and as dissolved ... | 02/02/2012 |
| 20120022035 | Polymorphic and Amorphous Salt Forms of Squalamine Dilactate The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of ... | 01/26/2012 |
| 20120014934 | Enhanced Natural Colors A natural color is concentrated to intensify color range and to provide useful amounts of one or more of anti-oxidant, nutritional, and anti-inflammatory compounds derived from one or more pigment sources. In a preferred embodiment, the pigment source is a fruit, a vege... | 01/19/2012 |
| 20120015901 | METHODS AND PREPARATIONS FOR PROTECTING CRITICALLY ILL PATIENTS The present invention relates to a method of treating a life threatening condition in a critically ill human patient with a non-infectuous disorder, wherein the critically ill patient is a patient receiving enteral or parenteral nutrition, the method comprising the step... | 01/19/2012 |
| 20120014915 | Estriol Therapy for Autoimmune and Neurodegenerative Disease and Disorders The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, including post-partum auto immune diseases) and more particularly. Most preferably the invention uses estrogens, estranges, estriol or estrogen receptor activ... | 01/19/2012 |
| 20120015911 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.... | 01/19/2012 |
| 20120009169 | SELF-FORMING PHOSPHOLIPIDIC GELS A phospholipid gel is spontaneously formed when combining a first phospholipid, a second phospholipid, and water, wherein the first phospholipid is a neutral phospholipid and the second phospholipid is a negatively charged phospholipid. The first and second phospholipid... | 01/12/2012 |
| 20120003291 | NANOBEAD RELEASING MEDICAL DEVICES Medical devices comprising nanobeads encapsulating one or more bioactive agents and methods of use thereof are provided.... | 01/05/2012 |
| 20120003158 | Biomarkers for Inflammatory Bowel Disease and Methods Using the Same The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis ... | 01/05/2012 |
| 20110318420 | FULVESTRANT NANOSPHERE/MICROSPHERE AND PREPARATIVE METHOD AND USE THEREOF Fulvestrant nanosphere/microsphere and preparation method and use thereof are provided in the present invention. The carrier material of the fulvestrant nanosphere/microsphere is methoxy ended polyethylene glycol-polylactic acid block copolymer. The nanosphere/microsphe... | 12/29/2011 |
| 20110311442 | DIRECT CELLULAR ENERGY DELIVERY SYSTEM A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a... | 12/22/2011 |
| 20110312929 | TREATMENT OF VAGINAL ATROPHY IN WOMEN WITH CARDIOVASCULAR PATHOLOGY RISK The present invention relates to the use of estriol in the preparation of a pharmaceutical formulation for vaginal administration with the capacity to self-limit the absorption of estriol, for the prevention and/or the treatment of urogenital atrophy in women said women... | 12/22/2011 |
| 20110301138 | PROCESS TO MAKE FUSIDIC ACID CREAM The invention discloses a process to make dermaceutical cream containing Fusidic acid which is formed in situ from Sodium Fusidate as the starting raw material, wherein Sodium Fusidate is converted into Fusidic acid under oxygen-free environment created using inert gas,... | 12/08/2011 |
| 20110301137 | DERMACEUTICAL GEL MADE USING SODIUM FUSIDATE AND A PROCESS TO MAKE IT The invention discloses a process to make dermaceutical gel containing Fusidic acid which is formed in situ from Sodium Fusidate as the starting raw material, wherein Sodium Fusidate is converted into Fusidic acid under oxygen-free environment comprising an inert gas, p... | 12/08/2011 |
| 20110301132 | METHODS OF TREATING URETHRITIS AND RELATED INFECTIONS USING FUSIDIC ACID Methods for the treatment and prevention of a bacterial infection caused by Neisseria gonorrhoeae, or Chlamydia trachomatis, or both Neisseria gonorrhoeae and Chlamydia trachomatis, such as urethritis, an ocular infection, or a pharyngeal inf... | 12/08/2011 |
| 20110294767 | BILE ACID RECYCLING INHIBITORS AND SATIOGENS FOR TREATMENT OF DIABETES, OBESITY, AND INFLAMMATORY GASTROINTESTINAL CONDITIONS Provided herein are methods of utilizing bile acid transport inhibitors and/or enteroendocrine peptide enhancing agents for the treatment of obesity, diabetes, and inflammatory gastrointestinal conditions.... | 12/01/2011 |
| 20110287112 | PROSTATE CANCER PROGRESSION INHIBITOR AND PROGRESSION INHIBITION METHOD A prostate cancer progression inhibitor comprises 4-(4-cyano-2-{[2-(4-fluoro-1-naphthyl)propanoyl]amino}phenyl)butyric acid, a salt thereof, a solvate thereof, or a prodrug thereof. 4-(4-Cyano-2-{[2-(4-fluoro-1-naphthyl)propanoyl]amino}phenyl)butyric acid is useful as a... | 11/24/2011 |
