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| Application No. | Application Title | Issue Date |
| 20100279941 | CD36 MODULATION AND USES THEREOF Methods, uses, kits and products are described for the prevention and treatment of ischemia-associated cardiopathies such as myocardial ischemia/reperfusion (I/R) injury, based on the selective modulation of CD36.... | 11/04/2010 |
| 20100239663 | COMPOSITION FOR FOODSTUFF FOR BINDING ACETALDEHYDE This invention relates to a non-toxic composition which bind acetaldehyde present in the stomach, intestine and/or colon. The composition comprises one or more acetaldehyde-binding compound(s) comprising one or more free sulphhydryl and/or amino groups. The compound(s) ... | 09/23/2010 |
| 20100233161 | NOVEL MULTIFUNCTIONAL COMPOUNDS FOR PHARMACEUTICAL PURPOSES The invention relates to a synthetic bifunctional non-antibody compound comprising one or more effector moieties and one or more binder moieties, wherein the effector moieties are operably linked to the binder moieties via a linker, the effector moieties are ligands to ... | 09/16/2010 |
| 20100233249 | CONTRACEPTIVE METHODS AND COMPOSITIONS RELATED TO PROTEASOMAL INTERFERENCE The present invention concerns the use of compositions and methods of regulating or evaluating fertility in an animal, in particular a mammal. In various embodiments of the invention, methods of contraception include inhibiting proteasome activity of a gamete, in partic... | 09/16/2010 |
| 20100234307 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY This invention relates to certain biphenyl amino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.... | 09/16/2010 |
| 20100234417 | THYROTROPIN RELEASING HORMONE RECEPTOR-OREXIN RECEPTOR HETERO-DIMERS/-OLIGOMERS A hetero-dimeric or hetero-oligomeric receptor, comprising at least one thyrotropin releasing hormone receptor subunit associated with at least one orexin receptor subunit.... | 09/16/2010 |
| 20100227824 | PHARMACEUTICAL PEPTIDES FOR THE TREATMENT OF INFLAMMATORY DISEASES The invention provides pharmaceutical compositions comprising at least a portion of a chemokine receptor or a G-protein coupled receptor. The pharmaceutical composition of the invention may be used for altering immune system functioning, for example, to treat an immune ... | 09/09/2010 |
| 20100222282 | METHOD OF DIAGNOSIS AND METHOD OF TREATMENT The present invention relates to a method for diagnosing higher susceptibility for diseases and conditions associated with low levels of AKG in a human or animal comprising the following steps: a) obtaining a biological sample from said human or animal; b) measuring the... | 09/02/2010 |
| 20100221261 | IAP BIR DOMAIN BINDING COMPOUNDS Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I or II or a salt thereof, in which R1, R2, R3, R100, R200... | 09/02/2010 |
| 20100216706 | Ghrelin Protects Substantia Nigra Dopamine Neurons A method of treating neurodegeneration of substantia nigra pars compacta (SNpc) dopamine neurons and compositions therefor are provided.... | 08/26/2010 |
| 20100216701 | Protein Kinase C Inhibitors for Prevention of Insulin Resistance and Type 2 Diabetes The present invention provides peptides and peptide analogs capable of inhibiting the activity of protein kinase C. The invention discloses use of such peptides and analogs for preparation of pharmaceutical compositions and methods for prevention, delay, suppression or ... | 08/26/2010 |
| 20100216725 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION The invention provides 4-amino-4-oxobutanoyl peptides of Formula I and the pharmaceutically salts and hydrates thereof. The variables R, R1, R6-R8, R16, R18 | |
| 20100210568 | THYROTROPIN RELEASING HORMONE FOR THERAPEUTIC APPLICATIONS The present invention is directed to the use of the peptide compound Pyr-His-Pro-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious d... | 08/19/2010 |
| 20100210567 | USE OF A TUFTSIN AS A THERAPEUTIC AGENT The present invention is directed to the use of the peptide compound Thr-Lys-Pro-Arg-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases,... | 08/19/2010 |
| 20100210564 | DRUG OR FOOD CONTAINING A PEPTIDE A pharmaceutical or a foodstuff including as an active ingredient a peptide containing Tyr (Y), Phe (F), Trp (W), or His (H) and a hydrophobic amino acid adjacent thereto, or an analog thereof.... | 08/19/2010 |
| 20100204112 | USE OF TYR-W-MIF-1 AND UROCORTIN 2 AS THERAPEUTIC AGENTS The present invention is directed to the use of the peptide compound Tyr-Pro-Trp-Gly-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectio... | 08/12/2010 |
| 20100203066 | POLYMERIC LINKERS CONTAINING PYRIDYL DISULFIDE MOIETIES The present invention provides polymeric linkers containing pyridyl disulfide moieties. Methods of making the polymeric linkers and methods of making conjugates using the same are also disclosed.... | 08/12/2010 |
| 20100204137 | THE USE OF SUBSTANCES FOR THE TREATMENT OF LOSS OF EYESIGHT IN HUMANS WITH GLAUCOMA AND OTHER DEGENERATIVE EYE DISEASES Methods for the prevention and treatment of ocular disorders, in particular glaucoma, through blocking the toxic effects of β-amyloid (Aβ) derivatives, and pharmaceutical compositions for effecting such prevention and treatment thereof.... | 08/12/2010 |
| 20100204159 | ORGANIC COMPOUNDS AND THEIR USES The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.... | 08/12/2010 |
| 20100196387 | Disulfide, Sulfide, Sulfoxide, and Sulfone Derivatives of Cyclic Sugars and Uses Thereof In the present invention there are disclosed new derivatives of dianhydrohexite mononitrate corresponding to formula (I), tautomers, pharmaceutically acceptable salts, prodrugs and solvates thereof: as well a... | 08/05/2010 |
| 20100197576 | Polypeptides or fusion proteins thereof inhibiting transmigration of leucocytes or growth and/or metastasis of cancer cells The present invention provides a polypeptide or its fusion protein derived from a paired immunoglobulin-like receptor α or β (PILRα or PILRβ), one of the transmembrane proteins, which inhibits the transmigration of leukocytes or the growth and/or metastasis of cance... | 08/05/2010 |
| 20100197605 | THERAPEUTIC USE OF PEPTIDE YGLF AND COMBINATION WITH KVLPVPQ The present invention is directed to the use of the peptide compound Tyr-Gly-Leu-Phe-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases,... | 08/05/2010 |
| 20100197607 | MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE Peptides are provided that comprise less than 24 amino acids. The peptides have an amino acid sequence selected from the group consisting of: (a) an amino acid sequence having from 4 to 6 contiguous amino acids of a reference sequence PEPTIDE 1; (b) an amino acid sequen... | 08/05/2010 |
| 20100197601 | USE OF A FIBRINOGEN RECEPTOR ANTAGONIST AND/OR FOLLICULAR GONADOTROPIN RELEASING PEPTIDE AS A THERAPEUTIC AGENT IN THE TREATMENT OF STREPTOCOCCUS PNEUMONIA INFECTION The present invention is directed to the use of the peptide compound Ac-Pen-Arg-Gly-Asp-Cys-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurode-generative diseases, infectious d... | 08/05/2010 |
| 20100197608 | USE OF MELANOTROPHIN-POTENTIATING FACTOR AS A THERAPEUTIC AGENT The present invention is directed to the use of the peptide compound Lys-Lys-GIy-Glu-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases,... | 08/05/2010 |
| 20100199361 | Role of Proteoglycans in Drug Dependence The invention provides methods of preventing or treating drug addiction, or ameliorating the craving for an addictive drug, as well as compounds, peptides, and pharmaceutical compositions that may be used to prevent or treat drug addiction or ameliorate the craving for ... | 08/05/2010 |
| 20100190710 | IL-23 RECEPTOR ANTAGONISTS AND USES THEREOF The present invention relates to IL-23 receptor antagonists and agonists. The use of IL-23 receptor antagonists in treating autoimmune and inflammatory disorders, as well as methods of identifying IL-23 receptor antagonists and agonists.... | 07/29/2010 |
| 20100189802 | Method for treatment of vascular hyperpermeability A method comprising preparing a vascular hyperpermeability treatment composition comprising an apoptosis regulating protein, a antioxidant, a mitochondrial modulator, a biological effector molecule, or combinations thereof in a form deliverable to a mammal; whereby an e... | 07/29/2010 |
| 20100190718 | METHODS FOR PREVENTING OR TREATING MITOCHONDRIAL PERMEABILITY TRANSITION The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum o... | 07/29/2010 |
| 20100189819 | NEURO-DEGENERATIVE INHIBITOR, NEURO-ENDOCRINE MODULATOR, AND NEURO-CEREBRAL METABOLISM ENHANCER Neuro-metabolic and endocrine-function regulating/modulating compositions, are disclosed. The compositions of the present invention comprise Selegiline Hydrochloride, Procaine Hydrochloride, Vinpocetine, trimethylglycine, and an ingredient selected from a group consisti... | 07/29/2010 |
| 20100190723 | PREVENTIVE OR THERAPEUTIC COMPOSITION FOR LIVER DISEASE This invention provides a composition having preventive and/or therapeutic effects on liver disease, which is highly effective, free of side effects, easily ingestible, and capable of long-term ingestion from the viewpoint of a cost and safety. This invention relates to... | 07/29/2010 |
| 20100190724 | USE OF MELANOCYTE-STIMULATING HORMONE RELEASE-INHIBITING FACTOR AS A THERAPEUTIC AGENT IN THE TREATMENT OF PSEUDOMONAS AERUGINOSA INFECTION The present invention is directed to the use of the peptide compound Pro-Leu-Gly-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious d... | 07/29/2010 |
| 20100190722 | SUBSTANCE P AND THYROTROPIN RELEASING HORMONE FOR THERAPEUTIC APPLICATIONS The present invention is directed to the use of the peptide compound Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodeg... | 07/29/2010 |
| 20100184706 | FAP-ACTIVATED CHEMOTHERAPEUTIC COMPOUNDS, AND METHODS OF USE THEREOF One aspect of the present invention relates to compounds for delivering chemotherapeutic agents to cancerous cells to reduce discomfort and deleterious side effects associated with systemic administration of such agents. Another aspect of the invention relates to method... | 07/22/2010 |
| 20100184663 | Methods and Compositions Related to Inhibition of Viral Entry Disclosed are compositions and methods for inhibiting viral entry.... | 07/22/2010 |
| 20100184707 | ANTICONVULSIVE PHARMACEUTICAL COMPOSITIONS The use of a substance selected from the group consisting of taurine, a taurine precursor, a taurine metabolite, a taurine derivative, a taurine analog and a substance required for the taurine biosynthesis, for manufacturing a pharmaceutical composition for preventing o... | 07/22/2010 |
| 20100184708 | USE OF GLY-PRO-GLU-OH (GPE) AS A THERAPEUTIC AGENT The present invention is directed to the use of the peptide compound Gly-Pro-Glu-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lun... | 07/22/2010 |
| 20100185219 | REINFORCED BIOLOGICAL MESH FOR SURGICAL REINFORCEMENT The invention is directed toward a composite material for use in a medical application, comprising a biological material and a reinforcement material. The biological material may be overlayed onto the reinforcement layer, or the material may be attached together. In one... | 07/22/2010 |
| 20100178313 | Implantable Degradable Biopolymer Fiber Devices Degradable fibers that include biopolymers, as well as implantable devices including one or more fibers made from degradable biopolymers, e.g., alginate, chitosan, hyaluronans or their derivatives. The devices provide a combination of degradability and biocompatibility ... | 07/15/2010 |
| 20100172943 | PEPTIDE NANOPARTICLES AND USES THEREFOR The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.... | 07/08/2010 |
