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| Application No. | Application Title | Issue Date |
| 20120128741 | MODIFIED HYALURONIC ACID POLYMER COMPOSITIONS AND RELATED METHODS The present application provides compositions comprising hyaluronic acid having low levels of functional group modification, mixtures formed by controlled reaction of such lightly modified hyaluronic acid with suitable difunctional or multi-functional crosslinkers, and ... | 05/24/2012 |
| 20120130300 | Therapeutic Methods Using Controlled Delivery Devices Having Zero Order Kinetics An injectable or implantable medical device having orifice(s) on the surface that release an active agent with zero-order release kinetics is described herein. The device is a hollow matrix of any size or shape, which can be made from both metal and non-metal surfaces. ... | 05/24/2012 |
| 20120107382 | ARTICLES INCORPORATING ABSORBENT POLYMER AND CERAGENIN COMPOUND An absorbent article includes an absorbent polymer and a ceragenin compound. The ceragenin compound has a sterol group and a plurality of cationic groups that mimic naturally occurring antimicrobial peptides. The ceragenin compound is associated with the absorbent polym... | 05/03/2012 |
| 20120108561 | STORAGE-STABLE, ANTI-MICROBIAL COMPOSITIONS INCLUDING CERAGENIN COMPOUNDS AND METHODS OF USE Storage-stable, anti-microbial compositions and products include a carrier and a ceragenin compound suspended in the carrier. Ceragenin compounds suspended in the carrier include a sterol backbone and a number of cationic groups attached to the sterol backbone via hydro... | 05/03/2012 |
| 20120045429 | Methods and Agent for Modulating the RNA Polymerase II-Histone Surface The present invention relates to the identification of an intranucleosomal DNA loop formed during transcription through a nucleosome and use of the same to identify an agent that modulates the RNA Polymerase II-histone surface.... | 02/23/2012 |
| 20120046263 | METHOD TO ALTER SEX RATIOS IN AVIAN OFFSPRING The present invention includes methods of influencing the sex chromosome ovulated by a female bird and altering the sex ratio in avian offspring by altering the exposure of an ovulating female bird to one or more stress hormones. In some aspects, the method includes exp... | 02/23/2012 |
| 20120034214 | METHODS AND KITS FOR DETERMINING THE PROGNOSIS OF PULMONARY SARCOIDOSIS The invention provides a method for determining the prognosis of pulmonary sarcoidosis in an individual subject, comprising conducting gene expression analysis on a sample from the subject. The sample is obtained by bronchoscopy under procedural methods not requiring ge... | 02/09/2012 |
| 20120035146 | IMPLANTS AND METHODS FOR TREATING INFLAMMATION-MEDIATED CONDITIONS OF THE EYE Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant deliv... | 02/09/2012 |
| 20120034271 | INJECTABLE IN-SITU CROSSLINKED HYDROGEL AND METHODS OF MAKING AND USING THEREOF The present invention discloses an injectable in-situ crosslinked hydrogel and its preparation method. The preparation method is as below: Filling the crosslinking active solution of at least one kind of the biocompatible macromolecules containing more than two thiol gr... | 02/09/2012 |
| 20120027863 | Pharmaceutical Compositions for Inhalation The invention provides microparticles for use in a pharmaceutical composition for Pulmonary administration, each microparticle comprising a particle of an active substance having, on its surface, particles of a hydrophobic material suitable for delaying the dissolution ... | 02/02/2012 |
| 20120004169 | MATERIALS AND METHODS FOR TREATMENT OF CANCER AND IDENTIFICATION OF ANTI-CANCER COMPOUNDS The subject invention pertains to the treatment of tumors and cancerous tissues and the prevention of tumorigenesis and malignant transformation through the modulation of JAK/STAT3 intracellular signaling. The subject invention concerns pharmaceutical compositions conta... | 01/05/2012 |
| 20120004204 | Methods for treating sexual dysfunction while decreasing cardiovascular risk Methods for treating female sexual dysfunction are provided. In particular, methods for treating a woman having HSDD by administering to the woman a therapeutically effective amount of an androgen, whereby the therapeutically effective amount of the androgen is administ... | 01/05/2012 |
| 20110318406 | Lecithin carrier vesicles and methods of making the same A hydrated lecithin carrier vesicle composition includes a lecithin-derived membrane-forming lipid vesicle in conditioned water for incorporation of an active ingredient to form a dispersed composition. A method of making the hydrated lecithin carrier vesicle includes u... | 12/29/2011 |
| 20110311442 | DIRECT CELLULAR ENERGY DELIVERY SYSTEM A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a... | 12/22/2011 |
| 20110306539 | PROCESS FOR MAKING PARTICLES FOR DELIVERY OF DRUG NANOPARTICLES A process for making particles for delivery of drug nanoparticles is disclosed herein. The process comprises the steps of (a) forming a suspension of drug nanoparticles by mixing a precipitant solution with an anti-solvent solution under micro-mixing environment, where ... | 12/15/2011 |
| 20110301135 | STABILIZATION OF GLUCOCORTICOID ESTERS WITH ACIDS The invention relates to nonaqueous pharmaceutical preparations comprising a glucocorticoid ester and an acid, and to the stabilization of glucocorticoid esters in such preparations by acids.... | 12/08/2011 |
| 20110286998 | METHODS FOR TREATING AND PREVENTING CANCERS THAT EXPRESS THE HYPOTHALAMIC-PITUITARY-GONADAL AXIS OF HORMONES AND RECEPTORS Methods are provided for treating HPG axis-positive cancers, preventing or slowing proliferation of cells of HPG axis-positive cancer origin, preventing HPG axis-positive cancers in a patient at risk of contracting such cancers, preventing or inhibiting an upregulation ... | 11/24/2011 |
| 20110286926 | DEGRADABLE HYDROGEL COMPOSITIONS AND METHODS This invention concerns an in situ biodegradable hydrogel drug delivery system in which the components are assembled in a manner that provides a mechanism for the timed cleavage of a particular amide bond in a covalently linked active agent or of the hydrogel structure.... | 11/24/2011 |
| 20110280799 | NANOCELLS FOR DIAGNOSIS AND TREATMENT OF DISEASES AND DISORDERS The present invention relates to novel nanocell compositions and their use in imaging, diagnostic and treatment methods. In one embodiment, nanocells tailored for imaging methods comprise a nanocore surrounded by a lipid matrix, and are modified to contain a radionuclid... | 11/17/2011 |
| 20110280922 | DEVICES AND METHODS FOR TREATING AND/OR PREVENTING DISEASES The invention relates to a therapeutic device for the delivery of therapeutic agents, e.g. a peptide such as leuprolide, via the vagina to a female mammal. In some embodiments, the invention also relates to methods for the treatment of obesity and eating disorders, diab... | 11/17/2011 |
| 20110274740 | METHODS OF REDUCING SYMPTOMS IN SUBJECTS USING SINGLE DOSAGE FORMS WITH TAPERING RELEASE RATES The present invention is directed to methods of reducing symptoms associated with an abrupt reduction in an endogenous or exogenous chemical in subjects, the methods comprising: (a) administering to the subject a single dosage form comprising an active agent, wherein th... | 11/10/2011 |
| 20110274746 | Therapeutic Liposomes and Methods For Producing and Using the Same The present invention provides therapeutic liposomes and methods for producing and using the same. In particular, therapeutic liposomes of the invention comprise phospholipids comprising C16-C22 fatty acid ester moieties. In some embodiments, these... | 11/10/2011 |
| 20110263553 | STEROID ANALOGUES FOR NEUROPROTECTION Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the n... | 10/27/2011 |
| 20110263554 | SCREEN FOR INHIBITORS OF FILOVIRUS AND USES THEREFOR The invention provides methods to identify agents useful to prevent, inhibit or treat viral infections, e.g. filovirus infections, as well as compositions having one or more agents to prevent, inhibit or treat viral infection.... | 10/27/2011 |
| 20110262550 | METHOD FOR TREATING A SKIN AILMENT A method for treating a skin ailment by applying a personal composition from a collapsible dispenser. The collapsible dispenser includes a collapsible bag at least partially surrounded by an elastically deformable member and, optionally, an outer container body. Potenti... | 10/27/2011 |
| 20110251162 | METHODS OF TREATMENT FOR MRSA INFECTIONS The present subject matter relates to pathogenesis of MRSA. Specifically, the present disclosures identifies the pro-inflammatory properties of PVL as the cause of MRSA. Viewed from this new perspective, the present subject matter achieves novel methods and apparatus fo... | 10/13/2011 |
| 20110250153 | OLIGOMERIC BIOSURFACTANTS IN DERMATOCOSMETIC COMPOSITIONS Oligomeric acylated biosurfactants (“OABs”) having low critical micelle concentrations of from about 1.0 ppm to about 200 ppm, preferably less than about 50 ppm, in an aqueous solution of Minimal Essential Media that can lower the surface tension in the aqueous MEM ... | 10/13/2011 |
| 20110236344 | Synthetic mimics of mammalian cell surface receptors: method and compositions The present invention relates to new synthetic receptors. More particularly, the present invention relates to the use of the synthetic receptors for delivering a protein, peptide, drug, prodrug, lipid, nucleic acid, carbohydrate or small molecule into a target cell via ... | 09/29/2011 |
| 20110223254 | FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM The present invention relates to dephenolic compounds, an example of which is shown below, which are functionalized, and polymers formed from the same. Polymers formed from the functionalized diphenolics are ... | 09/15/2011 |
| 20110224180 | NOVEL CHOLEST-4-EN-3-ONE OXIME DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND PREPARATION METHOD The present invention relates to novel chemical compounds, in particular cholest-4-en-3-one oxime derivatives and to the use thereof as medicaments, especially as cytoprotective medicaments, in particular neuroprotective, cardioprotective and/or hepatoprotective medicam... | 09/15/2011 |
| 20110217376 | POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME Disclosed is a temperature- and pH-sensitive hydrogel composed of a poly(amidoamine) oligomer only. The hydrogel is prepared in a simple manner and is readily released from the body. Further disclosed are a method for preparing the hydrogel and a drug carrier using the ... | 09/08/2011 |
| 20110206756 | DITHIOCARBAMATE METAL CHELATES AND METHODS OF MAKING AND USING THEREOF Described herein are compositions useful in anticancer treatment and prevention. The compositions are composed of (a) a dithiocarbamate metal chelate and (b) an amphiphile, wherein the amount of amphiphile is sufficient to produce a liposome or micelle. Methods for usin... | 08/25/2011 |
| 20110200582 | LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I).... | 08/18/2011 |
| 20110201539 | DETECTING SUCCINYLACETONE This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry.... | 08/18/2011 |
| 20110195903 | METHODS AND COMPOSITIONS FOR DETECTING RECESSIVE FAMILIAL FSGS AND USES THEREOF Described herein are genomic and proteomic biomarkers for the diagnosis of FSGS. Methods for diagnosing FSGS or a predisposition to develop FSGS using the described biomarkers are also provided. Further provided are methods for choosing a course of treatment or administ... | 08/11/2011 |
| 20110195031 | METHODS FOR THE USE OF PROGESTOGEN AS A GLUCOCORTICOID SENSITIZER Provided are methods and kits for administering progestogen as a glucocorticoid sensitizer to restore corticosteroid sensitivity or reverse the glucocorticoid insensitivity or enhance glucocorticoid sensitivity, in order to treat one or more glucocorticoid insensitivity... | 08/11/2011 |
| 20110190243 | DIAGNOSIS AND TREATMENT OF BACK PAIN The present invention relates to methods of diagnosing and/or treating lower back pain (LBP). In one embodiment, the invention relates to a system for diagnosis of a form of lower back pain in an individual, using a means to identify a type and/or a concentration of one... | 08/04/2011 |
| 20110189160 | Veterinary Topical Agent Methods and compositions for treating skin conditions in animals, which tend to have higher skin pH than humans, including wounds, ulcers, rashes, burns, abrasions, and other irritations and relevant injuries are provided. The invention contemplates the use of an aqueou... | 08/04/2011 |
| 20110182864 | COMPOSITIONS CONTAINING INCLUSION COMPLEXES The invention provides a composition containing particulate composite of a polymer and a therapeutic agent. The composition also contains a complexing agent. The polymer interacts with the complexing agent in a host-guest or a guest-host interaction to form an inclusion... | 07/28/2011 |
| 20110182849 | COMPOSITIONS AND METHODS FOR TREATING AN INTERVERTEBRAL DISC USING BULKING AGENTS OR SEALING AGENTS Effective compositions and methods for treating an intervertebral disc are provided. The compositions and methods comprise a bulking agent or sealing agent, the bulking agent or sealing agent adapted to be administered at or within the intervertebral disc, the bulking o... | 07/28/2011 |
