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| Application No. | Application Title | Issue Date |
| 20100280310 | Laparoscopic Gastric Band With Active Agents A gastric banding system is provided which generally includes a gastric band and an active agent, for example, a metabolic agent or satiety inducing agent. The band may be structured to contain the agent and permit controlled release of the agent to the patient while th... | 11/04/2010 |
| 20100272713 | Genetic Markers Associated with Endometriosis and Use Thereof The present invention relates to novel genetic markers associated with endometriosis and risk of developing endometriosis, and methods and materials for determining whether a human subject has endometriosis or is at risk of developing endometriosis and the use of such r... | 10/28/2010 |
| 20100272682 | METHOD FOR IMPROVING PHARMACOKINETICS The object of the present invention is to elevate the blood levels of a compound of formula I by co-administration with a cytochrome P450 inhibitor.... | 10/28/2010 |
| 20100272646 | METHOD FOR INDUCING LYMPHOID TISSUE AND MODULATING INTESTINAL HOMEOSTASIS Methods and products for modulating the lymphoid system, especially intestinal homeostasis between intestinal lymphoid tissues and gut flora using ligands for NOD1 and/or CCR6.... | 10/28/2010 |
| 20100272677 | HETEROCYCLIC ANTIVIRAL COMPOUNDS Compounds having the formula I wherein R1, R2, R3, R4, R5a, R5b, R5c and R6 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions an... | 10/28/2010 |
| 20100272761 | SYNTHESIS OF LIPOAMIDE-GRAFTED HIGH MOLECULAR COMPOUND AND METHOD THEREFOR The present disclosure provides polymer compounds binding with lipoamide produced by the reaction of the primary amine group of lipoamide with the carboxy group of polysaccharide compounds such as chondroitin sulfates, carboxymethyl celluloses, or hyaluronic acids; func... | 10/28/2010 |
| 20100267636 | USE OF CYTOCHROME P450-METABOLIZED DRUGS AND GRF MOLECULES IN COMBINATION THERAPY Combination therapies comprising a drug metabolized by cytochrome P450 and a growth hormone (GH)-inducing compound (such as a GRF molecule) are described, in which there are no or substantially no drug interactions.... | 10/21/2010 |
| 20100269223 | DIG-3 INSECTICIDAL CRY TOXINS DIG-3 Cry toxins, polynucleotides encoding such toxins, and transgenic plants that produce such toxins are useful to control insect pests.... | 10/21/2010 |
| 20100267635 | USE OF PROTEASE INHIBITORS AND GRF MOLECULES IN COMBINATION THERAPY Combination therapies comprising a protease inhibitor and a growth hormone (GH)-inducing compound (such as a GRF molecule) are described, in which there are no or substantially no drug interactions.... | 10/21/2010 |
| 20100266691 | Agents and Methods to Stimulate Bone Healing An agent for stimulating bone healing including isolated lysophosphatidic acid (LPA) and a hydrogel. A method of enhancing bone healing including identifying a damaged area of a bone and administering an agent comprising lysophosphatidic acid (LPA) is administered to th... | 10/21/2010 |
| 20100261651 | Purification and Use of a Factor for Supporting Wound Healing A process for manufacturing of a composition containing a purified factor for supporting wound healing selected from the group consisting of Hepatocyte Growth Factor (HGF) platelet derived growth factor (PDGF), Epidermal growth factor (EGF), transforming growth factor a... | 10/14/2010 |
| 20100260787 | Human sperm fibrous sheath (FS) proteins: new target antigens for use in therapeutic cancer vaccines and diagnostic screening and Methods of Using Same Cancer vaccines were demonstrated to be promising strategies for cancer treatment but the strategies are limited by the paucity of target antigens that provoke an effective immune response. We propose that sperm fibrous sheet proteins constitute a new class of potential... | 10/14/2010 |
| 20100260715 | HEPATITIS C VIRUS INHIBITORS The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Conse... | 10/14/2010 |
| 20100260831 | NON-PEGYLATED LIPOSOMAL DOXORUBICIN TRIPLE COMBINATION THERAPY The present invention relates to a method for treating metastatic breast cancer in an individual comprising administering to an individual in need thereof a dosing regimen which comprises administering to the individual nonpegylated liposomal doxorubicin, a taxane and a... | 10/14/2010 |
| 20100261652 | Tissue Adhesive Using Engineered Proteins There is provided in one embodiment of the disclosure a tissue adhesive composition comprising an engineered protein having repeated blocks of an elastin domain and at least one cell-binding domain and further comprising a polymer crosslinker. When the engineered protei... | 10/14/2010 |
| 20100256059 | REGULATION OF IMMUNE RESPONSES BY MODULATION OF THE FUNCTION OF ANTIGEN PRESENTING CELLS The present invention relates to the use of chaperonin 10 to modulate the function of antigen presenting cells. More particularly the invention resides in the modulation of cell surface expression of MHC molecules such as HLA.... | 10/07/2010 |
| 20100256060 | PEPTIDE PHARMACEUTICALS FOR NASAL DELIVERY Pharmaceutical products for nasal administration contain peptide active agents and are formulated with compounds that enhance bioavailability of the peptide active agents. In particular, citrates, fatty acids, sugar esters of fatty acids or acyl carnitines are used. In ... | 10/07/2010 |
| 20100255053 | MEDICAL IMPLANT WITH BIOACTIVE MATERIAL AND METHOD OF MAKING THE MEDICAL IMPLANT Embodiments of the invention include a medical device and a method of manufacturing a medical device having a porous scaffold in combination with a bioactive material. In some embodiments, particularly limited thicknesses of the bioactive material are applied within por... | 10/07/2010 |
| 20100257618 | Micro-RNA-Based Methods and Compositions for the Diagnosis and Treatment of Colon Cancer-Related Diseases The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.... | 10/07/2010 |
| 20100254916 | Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in compositions and use thereof The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions conta... | 10/07/2010 |
| 20100247650 | TREATMENT FOR PRE-ECLAMPSIA IN PREGNANT WOMEN USING TARGETED APHERESIS This invention uses “targeted apheresis” to treat pregnant women who are at risk of developing eclampsia. “Targeted Apheresis” is a process whereby the sFlt-1 receptors responsible for causing the disease symptoms are selectively removed from the blood by passin... | 09/30/2010 |
| 20100247734 | Methods for Making Nutritional Compositions Comprising Curcuminoids Disclosed are nutritional compositions and methods for preparing the compositions, comprising fat, protein, and carbohydrate, including a combination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin, which combination is solubilized in a polar oil having an HLB ... | 09/30/2010 |
| 20100240590 | PEPTIDES AND RELATED MOLECULES THAT BIND TO TALL-1 The present invention concerns therapeutic agents that modulate the activity of TALL-1. In accordance with the present invention, modulators of TALL-1 may comprise an amino acid sequence Dz2Lz4 wherein z2 is an amino acid residue and z 09/23/2010 | |
| 20100240587 | STABLE FORMULATIONS OF AMYLIN AND ITS ANALOGUES The invention relates to a soluble pharmaceutical composition for parenteral administration, which comprises an amylin peptide and an anionic surfactant, and methods for treatment of hyperglycemia.... | 09/23/2010 |
| 20100240584 | Nematode-extracted serine protease inhibitors and anticoagulant proteins Proteins which have activity as anticoagulants and/or serine protease inhibitors and have at least one NAP domain and are described. Certain of these proteins have factor Xa inhibitory activity and others have activity as inhibitors of factor VIIa/TF. These proteins can... | 09/23/2010 |
| 20100240588 | COMPOUND FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHIES The present invention relates to a compound of the following formula (I):
| 09/23/2010 |
| 20100239608 | PHARMACEUTICAL COMPOSITION CONTAINING A STABILISED mRNA OPTIMISED FOR TRANSLATION IN ITS CODING REGIONS The present invention relates to a pharmaceutical composition containing an mRNA that is stabilised by sequence modifications in the translated region and is optimised for the translation. The pharmaceutical composition according to the invention is particularly suitabl... | 09/23/2010 |
| 20100239526 | SUBSTITUTED IMIDAZOLYL-5,6-DIHYDROBENZO[N]ISOQUINOLINE COMPOUNDS The present invention relates to substituted imidazolyl-5,6-dihydrobenzo[n]isoquinoline compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazolyl-5,6-dihydrobenzo[n]isoquino... | 09/23/2010 |
| 20100239565 | METHODS OF TREATMENT OF SKIN ULCERS Methods for treating and/or preventing skin ulcers are provided featuring administration of pharmaceutical compositions comprising inhibitors of activity or expression Of Lp-PLA2 protein to patients subject to or at risk of developing skin ulcers.... | 09/23/2010 |
| 20100239635 | DRUG DELIVERY MEDICAL DEVICE Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one ac... | 09/23/2010 |
| 20100240589 | DIASTEREOMERIC PEPTIDES USEFUL AS INHIBITORS OF MEMBRANE PROTEIN ASSEMBLY The present invention relates to membrane binding diastereomeric peptides comprising amino acid sequences corresponding to a fragment of a transmembrane proteins, wherein at least two amino acid residues of the diastereomeric peptides being in a D-isomer configuration. ... | 09/23/2010 |
| 20100239545 | Methods of expressing LIM mineralization protein in non-osseous cells Methods of expressing LIM mineralization protein in non-osseous mammalian cells, such as stem cells or intervertebral disc cells (e.g., cells of the annulus fibrosus, or cells of the nucleus pulposus) are described. The methods involve transfecting the cells with an iso... | 09/23/2010 |
| 20100239578 | MODULATION OF SIRP-ALPHA - CD47 INTERACTION FOR INCREASING HUMAN HEMATOPOIETIC STEM CELL ENGRAFTMENT AND COMPOUNDS THEREFOR The invention relates to modulating the SIRPα-CD47 interaction in order to increase hematopoietic stem cell engraftment and compounds therefor. In some embodiments, there is provided isolated SIRPα and CD47 polypeptides, fragments and fusion proteins for enhancing hem... | 09/23/2010 |
| 20100239586 | PROCALIN POLYPEPTIDES, ANTIGENS, AND METHODS OF USE The disclosure provide polypeptides and polynucleotides encoding Triatoma sp. antigens and methods of using such polypeptides and polynucleotides.... | 09/23/2010 |
| 20100239691 | MODULATING LATENCY AND REACTIVATION OF MYCOBACTERIUM TUBERCULOSIS Methods for screening for agents that modulate the activation state, i.e., active growth or persistence, of Mycobacterium tuberculosis (Mtb), methods of treating an Mtb infection in a subject using agents identified by the screening methods, and methods for scree... | 09/23/2010 |
| 20100240583 | SOLUBLE PROTEIN AND UTILIZATION OF THE SAME The present invention relates to a method for screening a medicine using a protein, and a compound obtained by the screening method. A compound or a salt thereof inhibiting activity or expression of the protein of the present invention, a n... | 09/23/2010 |
| 20100240585 | IN VIVO CELL SURFACE ENGINEERING The present invention provides methods and compositions for the in vivo engineering of cell surfaces, such as tumor cell surfaces, with one or more immune co-stimulatory polypeptides. The methods, compositions and engineered cells are useful, for example, to stimulate a... | 09/23/2010 |
| 20100240586 | PEG MODIFIED EXENDIN OR EXENDIN ANALOG AND COMPOSITIONS AND USE THEREOF Exendins or exendin analogs modified by one or more PEG derivatives that may be linked to one or more amino acids of the exendins or exendin analogs are provided. The PEG derivatives may have branched structure set forth in any one of formulas I-IV. Compositions includi... | 09/23/2010 |
| 20100234295 | Treating Alzheimer's Disease And Osteoporosis And Reducing Aging Use of a composition for treating Alzheimer's disease, osteoporosis, sleep apnea, erectile dysfunction, McArdle disease, or a carbohydrate metabolism disorder, or for reducing aging or fatigue. The composition includes a first agent selected from the group consisting of... | 09/16/2010 |
| 20100233083 | MICROPARTICLES COMPRISING A CROSSLINKED POLYMER The present invention relates to a microparticle comprising a crosslinked polymer, which polymer is composed of a crosslinkable compound represented by the formula (I) wherein—X is a residue of a multifunctional radically polymerisable compound (having at least a func... | 09/16/2010 |
