Did You Know...
...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Application No. | Application Title | Issue Date |
| 20120129785 | COMPANION ANIMAL NUTRITION SYSTEM The invention encompasses a nutrition system for a companion animal that includes a plurality of pet food packets, wherein an amount of pet food corresponding to a single meal for a companion animal may be selected and wherein the amount of pet food is formulated to all... | 05/24/2012 |
| 20090214419 | SELF-ASSEMBLED BIODEGRADABLE POLYMERSOMES The invention concerns a block copolymer of polyethylene oxide and polycaprolactone, the polyethylene oxide having a number average molecular weight from about 2.0 to about 3.8 kD, the block copolymer having a fraction of polyethylene oxide of from about 11.8 to 18.8 pe... | 08/27/2009 |
| 20090205056 | METHOD OF SCREENING FOR MODULATORS OF MAP3K11 IN LIVER CANCER CELLS Detection of expression of the provided protein kinase in cancers is useful as a diagnostic, for determining the effectiveness of drugs, and determining patient prognosis. The encoded polypeptides further provides a target for screening pharmaceutical agents effective i... | 08/13/2009 |
| 20090180923 | SELF-MIXING CONTAINER WITH A RELEASABLE INTERNAL VESSEL AND ITS USAGE This application relates to a self-mixing container with a releasable internal vessel and its usage, wherein said self-mixing container comprises a container body, a double-walled external cap and an internal vessel, and through a corresponding production line, assembli... | 07/16/2009 |
| 20090093538 | Method for treating cancer The invention relates to a method of treating cancer in a subject, comprising administering to the subject an anti-cancer therapy and a compound that increases the oxidative stress of the cancer cells and activates p38.... | 04/09/2009 |
| 20080199407 | Drug Detoxification Protocol Using Microdosing This invention relates to use of an opioid receptor agonist in microdose quantities to reduce or eliminate the withdrawal symptoms associated with discontinuing drug use. The dosage of the agonist is reduced over an extended period of time.... | 08/21/2008 |
| 20080145386 | TRPV1+ sensory neurons control of beta-cell stress and islet inflammation in diabetes A process is disclosed for controlling inflammatory tissue access through release of neuropeptides, such as substance P (sP), to insulin-responsive sensory neurons, whereby simultaneous control of insulin sensitivity/resistance is manifested. In models of Type 1 and Typ... | 06/19/2008 |
| 20080125358 | Methods for Chk2 inhibitor patient selection The present invention contemplates a method to identify subjects that either have a tumor, or are at risk for tumor development, that are responsive to various inhibitors of an activated-Chk2 protein. Such Chk2 inhibitors may comprise a benzimidazole core structure, and... | 05/29/2008 |
| 20080103086 | METHODS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH THE SECRETION OF HMGB1 The present invention relates to a pharmaceutical composition comprising an antagonist of the phosphorylation of HMGB1, and a method for treating a condition associated with activation of the inflammatory cytokine cascade comprising administering an effective amount of ... | 05/01/2008 |
| 20080070826 | Cholesterol-reducing diet A method of treating cholesterol imbalance, high LDLs, and other metabolic syndrome problems and symptoms of osteoarthritis. The regimen preferred embodiment includes lipids as 60% or more of daily caloric content, protein up to 10%-15% of daily caloric content; and car... | 03/20/2008 |
| 20080051315 | Grp Receptor-Related Methods for the Treating and Preventing Fear-Related Disorders This invention provides a method for treating a subject afflicted with a fear-related disorder comprising administering to the subject a therapeutically effective amount of a gastrin-releasing peptide receptor agonist. This invention further provides a method for inhibi... | 02/28/2008 |
| 20080032966 | Small Molecule Inhibitors of Mrp1 and Other Multidrug Transporters A method of potentiating the activity of a therapeutic drug, like a chemotherapeutic drug or an antibiotic, in a cell or tissue, by inhibiting the efflux capability of a multidrug transporter are disclosed. The method is useful in the treatment of a cancer by sensitizin... | 02/07/2008 |
| 20080032926 | Knockout Non-Human Animal The present invention relates to a knockout non-human animal whose genome comprises a disruption in at least one allele of the PHF3 gene, useful in developing drugs for diseases with the onset of atopic dermatitis or the like; a totipotent cell such as an ES cell which ... | 02/07/2008 |
| 20080020964 | Test System for the Discovery of Substances for the Promotion of Neuraxonal Growth The invention relates to a method for identifying or testing active substances, which influence the growth and survival of nerve cells, wherein a cell is brought into contact with at least one substance and subsequently, within said cell, the mRNA of the β-actin or the... | 01/24/2008 |
| 20080003297 | Taste-masking oral dosage form and method of preparing the same A taste-masking oral dosage form. The taste-masking oral dosage form comprises a pharmaceutically active ingredient, and a starch, wherein the pharmaceutically active ingredient is packaged by the starch to form a microparticle. A method of preparing the taste-masking o... | 01/03/2008 |
| 20070281896 | Novel compositions and methods in cancer The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention prov... | 12/06/2007 |
| 20070275877 | Methods for Treating or Ameliorating Ghrelin-Associated Diseases and Disorders Methods for modulating the effective levels of ghrelin are disclosed. These methods include the use of amylin, amylin agonists and amylin antagonists to regulate the effective levels of ghrelin. Methods for the prevention, treatment, or amelioration of ghrelin-associate... | 11/29/2007 |
| 20070274918 | LINGO-1 structure This disclosure relates to LINGO-1 polypeptides, LINGO-1 polypeptide/ligand complexes, crystals of LINGO-1 polypeptides, crystals of LINGO-1 polypeptide/ligand complexes, and related methods and software systems. ... | 11/29/2007 |
| 20070265185 | Phosphorylated Vimentin Serving as a Marker of the Aggressiveness and/or Invasiveness of Tumors The invention relates to a novel method used for deter-mining the aggressiveness and/or invasiveness of a tumor. The invention also relates to a method for identifying an anticancer agent that makes it possible to reduce the aggressiveness and/or invasiveness of a tumor... | 11/15/2007 |
| 20070264252 | Modulators of Ms4a Gene Products A method of identifying a substance suitable for use in the treatment of a leukocyte-associated inflammatory disease that modulates the activity of a polypeptide encoded by a human MS4A gene. The method involves combining a candidate substance with said polypeptide and ... | 11/15/2007 |
| 20070258988 | Identification and Characterization of Multiple Splice Variants of the Mu Opioid Receptor Gene The present invention encompasses novel splice variant forms of the mu-opioid receptor-1 (MOR-1) and the polynucleotide sequences encoding the MOR-1 splice variants. The invention further encompasses methods of screening for compositions regulating the MOR-1 splice vari... | 11/08/2007 |
| 20070259037 | Method and composition for treatment of inflammatory conditions Methods of treating inflammation of the gastrointestinal tract and/or systemic or local inflammation by administering a steroid anti-inflammatory or a non-steroid anti-inflammatory drug in conjunction with polyunsaturated fatty acids or their derivatives and optionally ... | 11/08/2007 |
| 20070253946 | Axon Regeneration Promoter An axon regeneration promoter is disclosed that contains an inhibitor of RGM-like protein as an effective component. Inhibitors of RGM-like protein encompass inhibitors of RGM-like protein such as anti-RGM-like protein antibodies and Y27632, as well as antisense nucleic... | 11/01/2007 |
| 20070254043 | Sprayable beautifying composition The present invention is a method and apparatus for spraying makeup that masks imperfections in the skin including, but not limited to, freckles, tattoos, birthmarks, scars and post-laser surgery discoloration. The apparatus of the present invention is a hand-held spray... | 11/01/2007 |
| 20070254827 | Alpha-aminobenzyl-alpha,alpha,-diphosphoric acid selective chelation of beryllium A method of remediation of one or more of an animal, mineral, or vegetable for beryllium. The method includes the steps of applying α-aminobenzyl-α,α,-diphosphoric acid to the one or more of the animal, mineral, or vegetable; and allowing chelation of the beryllium.... | 11/01/2007 |
| 20070256146 | PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to ge... | 11/01/2007 |
| 20070249541 | Combined use of enzyme inhibitors and of pharmaceutical compositions thereof Provided are combinations of inhibitors of dipeptidyl peptidase IV (DP IV) and of enzymes having the same substrate specificity (DP IV-analogous enzymatic activity) and inhibitors of alanyl aminopeptidase (aminopeptidase N, APN) and of enzymes having the same substrate ... | 10/25/2007 |
| 20070249525 | Use of erythropoietin in the treatment of rheumatoid arthritis A novel use of the known protein erythropoietin (EPO), and/or a derivative, and/or a fragment thereof, is disclosed. EPO is used as a pharmaceutical for the treatment of chronic inflammations. A particularly beneficial result is seen in patients suffering from rheumatoi... | 10/25/2007 |
| 20070248590 | Modulators of CDC2-like kinases (CLKS) and methods of use thereof Provided herein are methods for using Cdc2-like kinase (Clk) modulators for treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardi... | 10/25/2007 |
| 20070248535 | Methods to treat or prevent hormone-resistant prostate cancer using siRNA specific for protocadherin-PC, or other inhibitors of protocadherin-PC expression or activity The invention is directed to compounds and methods for treating or preventing hormone-resistant prostate cancer using siRNA specific for protocadherin-PC, or other inhibitors of protocadherin-PC expression or activity, including antisense oligonucleotides and antibodies... | 10/25/2007 |
| 20070243181 | Irak1c Splice Variant And Its Use IRAK 1c splice variants and their preparation and use are described. The splice variants may be used in drug screening assays and methods for diagnosing medical conditions mediated by IRAK1c-modulating activity. ... | 10/18/2007 |
| 20070244031 | Methods and Compositions for Homozygous Gene Inactivation Using Collections of Pre-Defined Nucleotide Sequences Complementary Chromosomal Transcripts Methods and compositions for performing homozygous gene inactivation assays are provided. A feature of the subject methods is the use of a library of constructs that synthesize predefined nucleic acids, where each constituent predefined nucleic acid of the library is of... | 10/18/2007 |
| 20070244030 | Method for Assessing Cancerous State The present invention relates to a method for assessing a cancerous state of a mammal-derived specimen, which comprises: (1) a first step of measuring a methylation frequency of Neurofilament3 gene contained in a mammal-derived specimen or an index value having the corr... | 10/18/2007 |
| 20070244061 | Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondisn) and/or Wnt The present invention relates to a composition useful for the diagnosis of diseases associated with aberrant expression of the genes encoding the secreted proteins Futrin 1, 2, 3 and/or 4(=R-Spondin 2, 3, 1 and 4, respectively), e.g. in connection with tumors or disease... | 10/18/2007 |
| 20070244063 | BV8 NUCLEIC ACIDS AND POLYPEPTIDES WITH MITOGENIC ACTIVITY The present invention provides methods of using Bv8 polypeptides to induce endothelial cell proliferation and to enhance endothelial cell survival. Also provided herein are methods of screening for modulators of Bv8 activity. Furthermore, methods of treatment using Bv8 ... | 10/18/2007 |
| 20070243132 | Transdermal delivery of pharmaceutical agents The present invention generally relates to a vehicle useful for delivering a pharmaceutically active compound including a genetic molecule or composition. More particularly, the present invention provides microemulsions for transdermal delivery of pharmaceutically activ... | 10/18/2007 |
| 20070243192 | Growth hormone receptor antagonist cancer treatment The present invention provides methods and compositions for treating tumorigenic cells (e.g., mammary progenitor cancer cells), with growth hormone receptor antagonists (e.g., Pegvisomant), as well as methods and compositions for screening growth hormone receptor antago... | 10/18/2007 |
| 20070238640 | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents The invention features a method of treating an inflammatory condition in an individual, comprising administering an agent inhibits the interaction between a Toll-like receptor 2 (TLR2) and a high mobility group B (HMGB) polypeptide to the individual. The invention also ... | 10/11/2007 |
| 20070238660 | Light activated antiviral materials and devices and methods for decontaminating virus infected environments A method of inactivating viruses, articles for inactivating viruses and methods of manufacture of such articles are disclosed. Singlet oxygen generating dyes are attached to a substrate. Upon exposure to light, singlet oxygen is generated to inactivate viruses present. ... | 10/11/2007 |
| 20070238780 | Multifunctional enhancement systems for personal care, household, and wood products A personal care product, a household product, an industrial formulation, or a medicinal product of at least a fluorosurfactant and/or a natural or naturally-derived or synthetic, and/or *Eco-friendly (See Description) materials such as PEG-4 rapeseedamide, glycerth 2-co... | 10/11/2007 |
