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Class 436/528 - Carrier is organic


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Subject matter in which the carrier is an organic compound.
No. of applications: 42
Last issue date: 02/02/2012


1    
Application No.Application TitleIssue Date
20120028372RAPID DETECTION AND IDENTIFICATION OF ENERGETIC MATERIALS WITH SURFACE ENHANCED RAMAN SPECTROMETRY (SERS)
In one embodiment, a system includes a plurality of metal nanoparticles functionalized with a plurality of organic molecules tethered thereto, wherein the plurality of organic molecules preferentially interact with one or more analytes when placed in proximity therewith...
02/02/2012
20110236884MICROBUBBLES FOR AFFINITY SEPARATION
The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity mol...
09/29/2011
20110200986BIO-ASSAY USING LIQUID CRYSTALS
There is provided a method, an in vitro method and a detection system for detecting the presence of at least one biological molecule in at least one sample. The method can include, for example, providing a sample and/or a binding agent to a contact portion of a surface ...
08/18/2011
20110045608Imatinib Immunoassay
Novel conjugates and immunogens derived from imatinib and monoclonal antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of imatinib or its pharmacologically active salts in biological fluids....
02/24/2011
20110027915METHOD OF PRODUCING INSOLUBLE CARRIER PARTICLES, INSOLUBLE CARRIER PARTICLES, MEASUREMENT REAGENT, SPECIMEN ANALYZING TOOL, AND IMMUNOTURBIDIMETRIC ASSAY
The present invention provides a measurement reagent that is capable of suppressing nonspecific aggregation even when the amount of antibody to be carried is increased, and is capable of measuring in a wide measurement concentration range with high measurement sensitivi...
02/03/2011
20110020840METHOD AND KITS FOR DETECTING ANTIBODIES AGAINST THERAPEUTIC ANTIBODIES
The invention relates to the field of immunology and immunological diagnostics. More specifically, it relates to detection of the formation of antibodies in a subject that is treated with a therapeutic antibody. Provided is A diagnostic method for determining the presen...
01/27/2011
20100316563Method For The Preparation Of New Oligoclonal Antibodies
A process is provided for the preparation of antibodies or fragments thereof using a prokaryotic host cell containing DNA sequences encoding for said antibodies of fragments thereof, wherein said DNA sequence is derived from a coronary plaque sample. Compositions contai...
12/16/2010
20100292348DETECTION OF METHYLATED DNA AND DNA MUTATIONS
The present invention relates to various methods of detecting DNA methylation and defected DNA. In one embodiment, the invention provides a nanosensor bound to a probe that is complementary to a DNA methylation sequence....
11/18/2010
20100267170ROBUST, SELF-ASSEMBLED, BIOCOMPATIBLE FILMS
The present invention provides a composite material including a substrate having an oxide surface, and, a continuous monolayer on the oxide surface, the monolayer including a silicon atom from a trifunctional alkyl/alkenyl/alkynyl silane group that attaches to the oxide...
10/21/2010
20100240150MEASURING REAGENT AND TURBIDIMETRIC IMMUNOASSAY AND SAMPLE ANALYSIS TOOL USING THE SAME
A measuring reagent is provided that allows the amounts of insoluble carrier particles and monoclonal antibodies to be reduced, can improve measurement sensitivity with respect to an object to be measured in a low concentration range, allows the object to be measured in...
09/23/2010
20100233827METHOD FOR PRODUCING MOLECULE IMMOBILIZING SUBSTRATE, AND MOLECULE IMMOBILIZING SUBSTRATE
There is disclosed a method for producing a molecule immobilizing substrate, comprising at least the steps of:
    • forming,...
09/16/2010
20100190658COLORIMETRIC ASSAY FOR THE VISUAL DETECTION OF PRIMARY AND SECONDARY AMINES
The present invention concerns a novel method and kit system for the detection of solid-phase bound primary amines, secondary amines, or thiol groups comprising adding a fluid to said substrate and further comprising adding a novel reagents to said substrate and recordi...
07/29/2010
20100151443MICROFLUID SYSTEM AND METHOD TO TEST FOR TARGET MOLECULES IN A BIOLOGICAL SAMPLE
A system and method to test for the presence of target molecules in a biological test sample includes test molecules, a microfluidic chip, and irradiating and detection devices. The test molecules include bio-recognition molecules conjugable with the target molecules, a...
06/17/2010
20100136517MATRIX STABILIZATION OF AGGREGATION-BASED ASSAYS
Methods and apparatus for stabilization of aggregation-based assays are described. In various embodiments, anti-analytes are dispersed within a matrix. A solution containing analytes brought into contact with the matrix, so that analytes may permeate throughout at least...
06/03/2010
20100120023Detection of macromolecular complexes with harmonic cantilevers
Method and apparatus which uses harmonic cantilevers, such as used in atomic force microscopy, to detect variations in the attractive and repulsive forces on a solid surface as a result of macromolecular binding, for example, hybridization of a single stranded DNA molec...
05/13/2010
20100099203Substrates with surfaces modified with PEG
Compositions and methods of modifying surfaces using hydroxyl terminated PEG are described herein. The surfaces so modified are useful in detection of synthetic and natural product organic molecules, organometallics, biomolecules, particles, or cells....
04/22/2010
20100099113MINIMIZED SMALL PEPTIDES WITH HIGH AFFINITY FOR FACTOR VIII AND FACTOR VIII-LIKE PROTEINS
The present invention relates to the composition of small molecules and their use in the field of protein isolation, purification, stabilizing and/or enhancing its activity. In particular, the present invention relates to the synthesis and optimization of compounds comp...
04/22/2010
20100092985SOLID SUPPORT WITH ENHANCED DENSITY OF SIGNAL MATERIAL, KIT CONTAINING THE SAME AND METHOD OF DETECTING TARGET MATERIAL USING THE SAME
A solid support on which a labeled nucleic acid including a high density of signal materials, a kit containing the same, and a method of detecting a target material are provided....
04/15/2010
20100093109PIEZO DISPENSING OF A DIAGNOSTIC LIQUID INTO MICROFLUIDIC DEVICES
Assays in which samples of biological fluids are dispensed into the inlet port of a microfluidic device are improved in the accuracy and repeatability by dispensing the biological sample and/or associated liquids in small droplets and at timed intervals to control the o...
04/15/2010
20100086938MASS SPECTROMETRY OF BIOLOGICAL SAMPLE USING IMMUNOPRECIPITATION
It is intended to provide an analysis method for a biological sample with clinical significance, which is a system being simple to such an extent that it can be applied to a clinical field, and capable of capping a molecule ionization suppression in mass spectrometry. M...
04/08/2010
20100029016Nano-Sized Optical Fluorescence Labels and Uses Thereof
A composition is disclosed which is capable of being used for detection, comprising an encapsulated noble metal nanocluster. Methods for preparing the encapsulated noble metal nanoclusters, and methods of using the encapsulated noble metal nanoclusters are also disclose...
02/04/2010
20100009338Novel gold nanostructures and methods of use
The invention is drawn to novel nanostructures comprising hollow nanospheres and nanotubes for use as chemical sensors, conduits for fluids, and electronic conductors. The nanostructures can be used in microfluidic devices, for transporting fluids between devices and st...
01/14/2010
20090286330Immunoassay using insoluble carrier particles and reagent therefor
The present invention provides a reagent for an immunoassay comprising insoluble carrier particles which can give the values to be determined with high accuracy and reliability, and can be stored for a long time; an immunoassay using the reagent; and a method for keepin...
11/19/2009
20090226887Device for binding a target entity to a bait entity and detection methods using the same
The present invention pertains to a device for binding a target entity onto a bait entity that is immobilized on said device, comprising: a) a lipid layer having a negative net charge in an aqueous solution at a neutral pH; b) a two-dimensional matrix of anchoring compl...
09/10/2009
20090162946METHOD OF PREPARING A NANOPARTICLE FILM HAVING METAL IONS INCORPORATED
The present invention relates to a method of preparing a nanoparticle film having metal ions incorporated and to a film prepared by said method. The invention furthermore relates to uses of such a film....
06/25/2009
20090035876Electrochemical Assay
A method of determining the presence or amount of analyte in a fluid sample, which comprises: contacting a fluid sample with a binding reagent that comprises a plurality of cleavable species and wherein said species, when cleaved, are detectable using electrochemical me...
02/05/2009
20090023144METHOD AND ITS KIT FOR QUANTITATIVELY DETECTING SPECIFIC ANALYTE WITH SINGLE CAPTURING AGENT
The invention provides a method and its kit for quantitatively detecting a specific analyte with a single capturing agent. The quantitative detection of a specific analyte with a single capturing agent comprises: firstly combining the tested analyte with a solid phase c...
01/22/2009
20090017562RAMAN-ACTIVE REAGENTS
Raman Active Reagents (ERLs) are developed which use a nanoparticle substrate substantially covered with a mixed monolayer derived from a Raman active reporter molecule and an analyte binding molecule that both bind to the surface of the nanoparticle and thereby avoid t...
01/15/2009
20090005267IMMUNOASSAY FOR CROSS-REACTING SUBSTANCES
The present disclosure provides an immunoassay involving a multiplex of antibodies that recognize the same analyte but that have a different cross-reactivity to structurally similar compounds. Data obtained from the immunoassay involving observed analyte concentrations ...
01/01/2009
20080311679Biosensor Device
The invention relates to a biosensor device with an actuating element comprising a biorecognition element that is capable of binding target molecules from a sample of interest, wherein the actuating element comprises a polymer material, can be actuated by actuating mean...
12/18/2008
20080286816Detection of Methamphetamine Group Drugs
The present invention provides immunoassays which are highly specific for detection in biological samples of methamphetamine and other drugs of abuse of the methamphetamine group such as ecstasy and other ecstasy class drugs. More particularly, competitive assays are pr...
11/20/2008
20080261330Apparatus Components and Methods of Using Apparatus Components to Detect the Presence of an Analyte
Apparatus components including rigid supports suitable for use in an affinity column, affinity columns, and an affinity columns in fluid communication with an analytical column, such as in a high pressure liquid chromatography (HPLC) column, are disclosed. Methods of us...
10/23/2008
20080248594ORGANIC NON-SUGAR COMPOUNDS FOR PROTECTION OF BIOLOGICALLY ACTIVE MOLECULES AND CONJUGATE LABELS AND METHODS OF USE THEREOF
Provided are methods comprising the use of non-sugar organic compatible solutes for protection and preservation of the activity of biologically active molecules and conjugate labels. The methods are particularly adaptable for use in conjunction with immunoassays, such a...
10/09/2008
20080213747FLUORESCENT POLYMER SUPERQUENCHING-BASED BIOASSAYS
A chemical composition including a fluorescent polymer and a receptor that is specific for both a target biological agent and a chemical moiety including (a) a recognition element, (b) a tethering element, and (c) a property-altering element is disclosed. Both the fluor...
09/04/2008
20080206894Bioresponsive Hydrogels
The invention is a structure capable of detecting a target molecule, the invention including a functionalized polymer matrix having chemically reactive groups and at least one biomolecule attached to the chemically reactive groups to form a surface-modified bioresponsiv...
08/28/2008
20080206893Biosensor and Method
Surface plasmon resonance (SPR) sensor biointerface with a rigid thiol linker layer and/or interaction layer ligand loading with reversible collapse and/or iron oxide nanoparticle sensor response amplification....
08/28/2008
20080032319METHOD FOR DIAGNOSING COLON CANCER
The present invention relates to a method for diagnosing colon cancer by detecting a colon cancer specific antigen, defensin α6 from the blood of patient and a diagnostic kit for colon cancer comprising anti-defensin α6 antibody. The diagnostic kit for colon cancer of...
02/07/2008
20080003631Methods and materials for in vitro analysis and/or use of membrane-associated proteins, portions thereof or variants thereof
Methods and materials use template-directed assembly of polypeptides and optionally additional reagents to analyze the functionality of membrane-associated proteins, such as, for example, portions of transmembrane proteins, membrane-associated proteins, and others prote...
01/03/2008
20070259452CONTROLLED TRANSPORT THROUGH MULTIPLE REVERSIBLE INTERACTION POINT MEMBRANES
A method for causing a membrane to become permeable to a first chemical species, in which the membrane is contacted with a solution comprising a second chemical species. The membrane comprises a polyelectrolyte complex film comprising a positively-charged polyelectrolyt...
11/08/2007
20050239217Fluorogenic homogeneous binding assay methods and compositions
Disclosed are binding substrate compositions, methods and kits useful for, among other things, detecting and/or characterizing binding interactions between molecules of interest. ...
10/27/2005
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