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| Application No. | Application Title | Issue Date |
| 20120028372 | RAPID DETECTION AND IDENTIFICATION OF ENERGETIC MATERIALS WITH SURFACE ENHANCED RAMAN SPECTROMETRY (SERS) In one embodiment, a system includes a plurality of metal nanoparticles functionalized with a plurality of organic molecules tethered thereto, wherein the plurality of organic molecules preferentially interact with one or more analytes when placed in proximity therewith... | 02/02/2012 |
| 20110294230 | Lyophilization of Colloidal Metals for Surface Enhanced Raman Scattering An assay and method of making same for use in SERS spectroscopy. The assay includes colloidal particles of a metal, which have been lyophilized. The lyophilized particles of metal produce a SERS active solution when reconstituted. The lyophilized particles of metal may ... | 12/01/2011 |
| 20110244479 | Plasmon Resonant Particles, Methods and Apparatus A method and apparatus for interrogating a target having a plurality of plasmon resonant particles (PREs) distributed in the target are disclosed. In the method, a field containing the target is illuminated, and one or more spectral emission characteristics of the light... | 10/06/2011 |
| 20110200986 | BIO-ASSAY USING LIQUID CRYSTALS There is provided a method, an in vitro method and a detection system for detecting the presence of at least one biological molecule in at least one sample. The method can include, for example, providing a sample and/or a binding agent to a contact portion of a surface ... | 08/18/2011 |
| 20110136099 | Multiplexed Analyses of Test Samples The present disclosure describes methods, devices, reagents, and kits for the detection of one or more target molecules that may be present in a test sample. The described methods, devices, kits, and reagents facilitate the detection and quantification of a non-nucleic ... | 06/09/2011 |
| 20110124008 | NOVEL Au/Ag CORE-SHELL COMPOSITE USEFUL FOR BIOSENSOR In accordance with an aspect of the present invention, there is provided an Au/Ag core-shell composite including an Au nanoparticle; an Ag nanoparticle layer surrounding the Au nanoparticle; and a receptor having a target material recognition site bondable or reactable ... | 05/26/2011 |
| 20110124132 | CENTRIFUGAL MICRO-FLUIDIC DEVICE AND METHOD FOR DETECTING TARGET IN FLUID SAMPLE Disclosed are a centrifugal micro-fluidic device and an immunosorbent assay method using the same. In particular, a centrifugal micro-fluidic device having a plurality of micro-fluidic structures placed in a disc type platform to simultaneously conduct several immunosor... | 05/26/2011 |
| 20110124131 | METHOD FOR PREPARING METAL NANOPARTICLE USING METAL BINDING PROTEIN The present invention relates to a method of preparing heavy metal nanoparticles using a heavy metal-binding protein. More specifically, relates to a method for preparing heavy metal structures, comprising the steps of: culturing a microorganism transformed with a gene ... | 05/26/2011 |
| 20110045607 | PROBE COMPOSITE, METHOD FOR MANUFACTURING THE SAME, METHOD FOR USING THE SAME, AND CONTRAST AGENT INCLUDING THE SAME A probe composite for photoacoustic imaging includes a first probe and the second probe mixed with each other. The first probe includes a first ligand and a first nanorod conjugated to the first ligand. The first ligand specifically interacts with a first target. The se... | 02/24/2011 |
| 20110014724 | METHOD OF DETECTING BIOPRODUCTS USING LOCALIZED SURFACE PLASMON RESONANCE SENSOR OF GOLD NANOPARTICLES Disclosed is a method of detecting bioproducts using Localized Surface Plasmon Resonance (LSPR) of gold nanoparticles, which can diagnose bioproducts based on changes in the maximum wavelength occurred by an antigen-antibody reaction after immobilization of the gold nan... | 01/20/2011 |
| 20100317039 | MOLDING WITH EMBEDDED COUPLING PARTICLES FOR BIOMOLECULES The invention relates to a molding, comprising a matrix in a material, selected from the group consisting of metal, ceramic and polymer synthetic material, and coupling particles embedded in the matrix, wherein a proportion of the surface of the molding in a geometrical... | 12/16/2010 |
| 20100304502 | DETECTION METHOD AND DETECTION KIT A detection method for detecting a substance such as a virus which achieves enhanced detection sensitivity even in trace amounts of a substance to be detected and is also simple and superior in visual determinability is disclosed, comprising contacting a complex of a su... | 12/02/2010 |
| 20100291542 | RAPID IMMUNOCHROMATOGRAPHIC DETECTION BY AMPLIFICATION OF THE COLLOIDAL GOLD SIGNAL The present invention relates to a method for rapid immunochromatographic detection of a target in a sample by double sandwich immunoassay detection, wherein the target is an antibody and/or an antigen, using different colloidal gold conjugates conjugated with a first a... | 11/18/2010 |
| 20100267056 | DIFFERENTIAL LABELLING METHOD The invention relates to a method for differentially labelling one or more entities, together comprising distinct reactive sites. The invention further relates to an entity that has been labelled by a method according to the invention and to a diagnostic kit comprising ... | 10/21/2010 |
| 20100255610 | RAPID QUANTIFICATION ASSAY INVOLVING CONCENTRATED AND LIGAND-COATED GOLD COLLOID A concentrated and ligand-coated gold colloid and a method of preparing it. Also disclosed is a rapid biomolecule quantification assay involving the use of the concentrated gold colloid and an apparatus for performing the assay.... | 10/07/2010 |
| 20100233825 | CHEMICAL SENSOR ELEMENT, SENSING APPARATUS, AND SENSING METHOD A chemical sensor element contains a resonator having a first reflector in which particles of a fine metal structure are arranged two-dimensionally and periodically is counterposed with interposition of a dielectric layer to a second reflector, wherein the resonance wav... | 09/16/2010 |
| 20100178713 | TARGET SUBSTANCE-DETECTING ELEMENT A substrate of a target substance-detecting element for detecting a target substance in a specimen based on localized surface plasmon resonance comprises a supporting member and a metal nano-dot group provided on the supporting member, metal nano-dots each of which is c... | 07/15/2010 |
| 20100167290 | MOLECULE ATTACHMENT TO NANOPARTICLES Disclosed herein are molecule-modified nanoparticles and methods of making and using the same. More specifically, disclosed herein are molecule-modified nanoparticles wherein the molecule is attached to the surface of the nanoparticle via an oligonucleotide. Also disclo... | 07/01/2010 |
| 20100159471 | PROCESS FOR PRODUCTION OF COLLOIDAL GOLD AND COLLOIDAL GOLD It is an object of the present invention to provide a method for producing gold colloid having a targeted particle size, a sharp particle size distribution and a uniform and perfect spherical shape. The present invention relates to a method for producing gold colloid in... | 06/24/2010 |
| 20100140112 | Nanoparticle Marker, Diagnostic Methods Using the Same and Diagnostic Kit and Apparatus Using the Same A diagnostic kit disclosed herein comprises a nanoparticle-biomaterial complex, an extraction solution, a collection electrode, and a current peak measurement unit. The nanoparticle-biomaterial complex comprises: one or more nanoparticles selected from a metal group con... | 06/10/2010 |
| 20100135856 | NANOPARTICLE FOR DETECTING BIOMATERIALS AND BIOSENSOR BY USING THE NANOPARTICLE Provided are a nanoparticle for detecting biomaterials and a biosensor by using the nanoparticle. The nanoparticle includes a metal nanostructure around which an electric field is induced by localized surface plasmon resonance when light is irradiated onto a surface of ... | 06/03/2010 |
| 20100120023 | Detection of macromolecular complexes with harmonic cantilevers Method and apparatus which uses harmonic cantilevers, such as used in atomic force microscopy, to detect variations in the attractive and repulsive forces on a solid surface as a result of macromolecular binding, for example, hybridization of a single stranded DNA molec... | 05/13/2010 |
| 20100092985 | SOLID SUPPORT WITH ENHANCED DENSITY OF SIGNAL MATERIAL, KIT CONTAINING THE SAME AND METHOD OF DETECTING TARGET MATERIAL USING THE SAME A solid support on which a labeled nucleic acid including a high density of signal materials, a kit containing the same, and a method of detecting a target material are provided.... | 04/15/2010 |
| 20100086938 | MASS SPECTROMETRY OF BIOLOGICAL SAMPLE USING IMMUNOPRECIPITATION It is intended to provide an analysis method for a biological sample with clinical significance, which is a system being simple to such an extent that it can be applied to a clinical field, and capable of capping a molecule ionization suppression in mass spectrometry. M... | 04/08/2010 |
| 20100087013 | Nanosensors and related technologies The present invention generally relates to nanotechnology and sub-microelectronic circuitry, as well as associated methods and devices, for example, nanoscale wire devices and methods for use in determining nucleic acids or other analytes suspected to be present in a sa... | 04/08/2010 |
| 20100075441 | RAPID IMMUNOCHROMATOGRAPHIC DETECTION BY AMPLIFICATION OF THE COLLOIDAL GOLD SIGNAL The present invention relates to a method for rapid immunochromatographic detection of a target in a sample, wherein the target is an antibody and/or an antigen, using different colloidal gold conjugates conjugated with a specific antibody and some oligonucleotides and ... | 03/25/2010 |
| 20100062545 | BIOASSAYS USING PLASMONIC SCATTERING FROM NOBLE METAL NANOSTRUCTURES The present invention relates to detecting and/or measuring scattering effects due to the aggregating metallic nanostructures or the interaction of plasmonic emissions from approaching metallic nanoparticles. The scattering effects may be measured at different angles, d... | 03/11/2010 |
| 20090325316 | Compositions for use as a Signal Generation Component and Methods of Using Same Compositions suitable for use as signal generation components of an immunoassay, and methods for their use. According to one aspect of the invention, the composition includes a carrier having a coating of an aminodextran and a metal chelate incorporated therein. The met... | 12/31/2009 |
| 20090311806 | GOLD-BINDING PROTEIN AND USE THEREOF A protein utilizing an anti-gold antibody and a gold-binding side which is a part of the anti-gold antibody is constructed. This protein is capable of specifically binding to gold. This protein or a complex protein containing such a protein can be used for the detection... | 12/17/2009 |
| 20090275145 | METAL-ENHANCED FLUORESCENCE FOR POLARIZATION-BASED AFFINITY ASSAYS A method and kit for determining the quantity of an analyte include providing a functionalized substrate and a reagent. The functionalized substrate includes metallic nanoparticles and a plurality of substantively identical bioactive target molecules affixed to a substr... | 11/05/2009 |
| 20090263787 | METHOD FOR SCREENING OF INFECTIOUS AGENTS IN BLOOD This invention discloses using SPR technology to simultaneously and qualitatively detect the presence of infectious agent related antibodies and/or antigens in a serum sample, which can be used to screen for infectious agents in blood. It also discloses an efficient for... | 10/22/2009 |
| 20090233380 | Methods and Compositions of Conjugating Gold to Biological Molecules The present application describes methods for conjugating gold to biological molecules and conjugates resulting from the same. The method provides superior gold conjugated biomolecules with higher sensitivity than those made from conventional gold conjugation methods.... | 09/17/2009 |
| 20090203153 | METAL PARTICLE AND A TESTING METHOD USING THE SAME An object of the present invention is to provide a metal particle with which a highly-sensitive testing method can be conducted, and a testing method using such metal particle. The present invention provides a metal particle, which is produced by coating a metal particl... | 08/13/2009 |
| 20090168068 | Coated metal surface on solid support for displacement reactions A coated metal surface on a solid support, wherein the coating consists of a self-assembled monolayer (SAM) of oligo(ethylene glycol)-terminated amide group-containing alkyl thiols firmly attached to the metal surface via the thiol-end and low molecular weight antigens ... | 07/02/2009 |
| 20090162944 | Method of Measuring Biomolecular Reaction at Ultrahigh Speed According to the present invention, a method for ultrafast and precise measurement and analysis of biomolecules using a small sample was established, and moreover, a compact and simple micro fluid device for implementing the method was provided. Using the method and the... | 06/25/2009 |
| 20090117669 | SUBSTRATE FOR TARGET SUBSTANCE DETECTING DEVICE, TARGET SUBSTANCE DETECTING DEVICE, TARGET SUBSTANCE DETECTING APPARATUS AND METHOD USING THE SAME, AND KIT THEREFOR A substrate for forming a target substance detecting device includes a supporting member, an underlying layer disposed on a surface of the supporting member, and a metal pattern layer, disposed on a surface of the underlying layer, for being bound to a target substance ... | 05/07/2009 |
| 20090098662 | DETERMINING THE PRESENCE OR AMOUNT OF A METAL-LABELLED SPECIES A method for determining the presence or amount of a metal-labelled species in a sample may include causing the metal of the metal-labelled species in the sample to form a soluble electrochemically-active complex which is stable relative to moieties present or potential... | 04/16/2009 |
| 20090098663 | NOVEL WATER-SOLUBLE NANOCRYSTALS COMPRISING A POLYMERIC COATING REAGENT, AND METHODS OF PREPARING THE SAME Disclosed is a water soluble nanocrystal comprising a nanocrystal core comprising at least one metal M1 selected from an element of main group II, subgroup VIIA, subgroup VIIIA, subgroup IB, subgroup IIB, main group III or main group IV of the periodic system of the ele... | 04/16/2009 |
| 20090081345 | Identification of Prion Proteins in Milk The present invention relates to the use of milk or a derivative thereof for identifying prion proteins, preferably PrPSc prion proteins, in a mammal. The present invention is also directed to a method for identifying prion proteins, preferably PrPSc 03/26/2009 | |
| 20090075396 | Biosensors Methods for detecting a biological interaction comprising administering a substrate comprising a ligand attached to the substrate wherein the ligand binds to a receptor and wherein a signal is produced. Also disclosed is a biosensor comprising a substrate and a ligand w... | 03/19/2009 |
