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| Application No. | Application Title | Issue Date |
| 20100291711 | INTEGRATED SENSOR MICROSYSTEM AND METHOD FOR DETECTING BIOMOLECULES IN LIQUID An integrated microsystem for detecting biomolecules is made up of a micropump for delivering a sample, a microsensor for detecting the presence of a target biomolecule in the sample, a microheater for maintaining the temperature of operation, a microcontroller for regu... | 11/18/2010 |
| 20100216256 | NANOBELT-BASED SENSORS AND DETECTION METHODS A biosensor is provided which includes a substrate, a source electrode on the substrate, a drain electrode on the substrate, and at least one functionalized nanobelt on a surface of the substrate between the source electrode and the drain electrode. Methods for sensing ... | 08/26/2010 |
| 20100190270 | SYSTEM AND METHODS FOR DETECTING A GASEOUS ANALYTE IN A GAS Systems and methods for detecting a gaseous analyte utilize a micromechanical piezoelectric resonator having a functionalization layer configured to bind with the gaseous analyte. The functionalization layer may include a layer of carbon nanotubes affixed to the resonat... | 07/29/2010 |
| 20100135856 | NANOPARTICLE FOR DETECTING BIOMATERIALS AND BIOSENSOR BY USING THE NANOPARTICLE Provided are a nanoparticle for detecting biomaterials and a biosensor by using the nanoparticle. The nanoparticle includes a metal nanostructure around which an electric field is induced by localized surface plasmon resonance when light is irradiated onto a surface of ... | 06/03/2010 |
| 20100099203 | Substrates with surfaces modified with PEG Compositions and methods of modifying surfaces using hydroxyl terminated PEG are described herein. The surfaces so modified are useful in detection of synthetic and natural product organic molecules, organometallics, biomolecules, particles, or cells.... | 04/22/2010 |
| 20100086488 | HYDROPHILIC NANOPARTICLES WITH FUNCTIONAL SURFACE GROUPS, PRODUCTION AND USE THEREOF The present invention relates to nanoparticles having a hydrophilic surface coating, to methods of production thereof and to the use thereof in biological, molecular biological, biochemical and medical applications.... | 04/08/2010 |
| 20100087013 | Nanosensors and related technologies The present invention generally relates to nanotechnology and sub-microelectronic circuitry, as well as associated methods and devices, for example, nanoscale wire devices and methods for use in determining nucleic acids or other analytes suspected to be present in a sa... | 04/08/2010 |
| 20100081216 | METHOD AND DEVICE FOR RAPID PARALLEL MICROFLUIDIC MOLECULAR AFFINITY ASSAYS Disclosed are methods and devices for rapid parallel molecular affinity assays performed in a microfluidic environment. The invention exploits hydrodynamic addressing to provide simultaneous performance of multiple assays in parallel using a minimal sample volume flowin... | 04/01/2010 |
| 20100040553 | SPHERICAL FERRITE NANOPARTICLE AND METHOD FOR PRODUCTION THEREOF A method for producing spherical ferrite nanoparticles includes the steps of: preparing a first aqueous solution containing a disaccharide, an alkaline, an oxidation agent, seed particles and divalent iron ions; and conducting particle growth in the first aqueous soluti... | 02/18/2010 |
| 20090124026 | Use of Perfluoropolymer Submicrometric Latexes in the Determination of Molecular Interactions By Laser Light Scattering (Lls) Use of a latex of perfluorinated polymers having particles with an average diameter between 5 and 200 nm for determining the binding constant of two interacting molecular species by Laser Light Scattering (LLS), said polymeric particles comprising on the surface an amph... | 05/14/2009 |
| 20090124025 | Nanowire-based sensor configurations This invention provides nanowire based molecular sensors and methods for detecting analytes in a microfluidic system. Methods for sensing analytes include detecting changed electrical parameters associated with contact of a nanowire with the analyte in a microfluidic sy... | 05/14/2009 |
| 20090104634 | ONE-STEP IMMUNOASSAYS EXHIBITING INCREASED SENSITIVITY AND SPECIFICITY The present disclosure relates to immunoassays for detecting or quantifying at least one analyte of interest in a test sample which exhibits improved sensitivity and specificity compared to the immunoassay formats known in the art.... | 04/23/2009 |
| 20090075396 | Biosensors Methods for detecting a biological interaction comprising administering a substrate comprising a ligand attached to the substrate wherein the ligand binds to a receptor and wherein a signal is produced. Also disclosed is a biosensor comprising a substrate and a ligand w... | 03/19/2009 |
| 20090023135 | DETECTION OF ENHANCED MULTIPLEX SIGNALS BY SURFACE ENHANCED RAMAN SPECTROSCOPY Various methods of using Raman-active or SERS-active probe constructs to detect analytes in biological samples, such as the nucleic acid and/or protein-containing analytes in a body fluid are provided.... | 01/22/2009 |
| 20080188010 | BIOSENSOR SUBSTRATE It is an object of the present invention to provide a biosensor substrate that prevents non-specific adsorption and is used for immobilizing a physiologically active substance. The present invention provides a biosensor substrate which comprises an inorganic oxide film ... | 08/07/2008 |
| 20080166706 | Novel gold nanoparticle aggregates and their applications The invention is drawn to novel gold nanoparticles that are used in a dual optical method for sensitive and selective detection of antigens. The gold nanoparticle aggregates are synthesized from gold hydrochloride and sulfur salts in an aqueous solution. The aggregates ... | 07/10/2008 |
| 20080160637 | ENHANCEMENT OF SENSITIVITY OF FLUOROPHORE MEDIATED BIOSENSING AND BIOIMAGING A method of enhancing fluorescence emission in a fluorophore-mediated sensing, biosensing, imaging, and bioimaging. An example of biosensing is a fluorophore-mediated sandwich immunoassay with a 1° monoclonal antibody against a target analyte and a fluorophore-linked 2... | 07/03/2008 |
| 20080108096 | ANALYTICAL METHOD The instant invention describes an analytical assay to accurately measure an analyte in the presence of an interfering substance. ... | 05/08/2008 |
| 20080064121 | Peptide-Coated Nanoparticles with Graded Shell Compositions A peptide-coated nanoparticle that includes a nanocrystal core surrounded by a graded shell that is composed of at least two different semiconductor molecules. At least one peptide is attached to the surface of the graded shell to render the nanoparticle biocompatible. ... | 03/13/2008 |
| 20080044928 | Method for the Preparation of Ready-to-Use Support for Rapid Enzyme-Linked Immunosorbent Assay (Elisa) The present invention provides a method for the preparation of ready-to-use solid support for ELISA for rapid identification and quantitative estimation of protein/antigen in the test samples, and performances of the assay itself. The invention also provides for a quick... | 02/21/2008 |
| 20070292889 | Immunoassay magnetic trapping device A system for immunoassaying a sample comprising providing magnetic beads, connecting signal molecules to the beads, connecting the sample to the magnetic beads with the connected signal molecules, magnetically trapping the magnetic beads with the connected signal molecu... | 12/20/2007 |
| 20070287198 | Directed-flow assay device A diagnostic assay device that directs an applied sample to the analytical membrane of a directed flow device. The device has a sample receiving port defined by layers of built-up material on one end of the test strip. The port contains the sample and specifically direc... | 12/13/2007 |
| 20070281311 | Systems and Methods for Performing Measurements of One or More Materials Systems and methods for performing measurements of one or more materials are provided. One system is configured to transfer one or more materials to an imaging volume of a measurement device from one or more storage vessels. Another system is configured to image one or ... | 12/06/2007 |
| 20070238140 | Method For Multiplex Bead-Based Assays Using Chemiluminescence and Fluorescence A method for detecting a target analyte in a sample, the method having the steps of: binding the target analyte to a fluorescently coded particle capable of specifically binding to the target analyte; labeling the target analyte with a first chemiluminescence component;... | 10/11/2007 |
| 20070224604 | Method of Determining the Presence and/or Concentration of Substances of Interest in Fluids Magnetic particles coated with specific antibodies for substances of interest are introduced into a fluid sample. Over time and with agitation, the magnetic particles become attached to the substance of interest within the fluid. The fluid is then introduced to a magnet... | 09/27/2007 |
| 20070212794 | Magnetic immunoassay system A magnetic immunoassay system with a mechanism for compensating the direct current residual magnetic field in the vicinity of the specimen measurement position, in a direction perpendicular to the magnetic marker direction of magnetization for the measurement target. Th... | 09/13/2007 |
| 20070202611 | Simple membrane assay method and kit The present invention is to provide a simple membrane assay method for detecting or quantitating an analyte in a specimen sample using an assay device equipped with a membrane bound with a capture-substance to capture the analyte, comprising the steps of filtering a spe... | 08/30/2007 |
| 20070178607 | Microparticle-based methods and systems and applications thereof Microparticle-based analytical methods, systems and applications are provided. Specifically, the use of resonant light scattering as an analytical method for determining either or both a particle's identity and the presence and optionally, the concentration of one or mo... | 08/02/2007 |
| 20070172429 | Labeling compositions and methods of use for deterrent trackability Compositions and methods for controlling and tracking items are provided. More particularly, labeling compositions useful as a coding system to deter diversion of items of medication or other valued items are provided, wherein the labeling compositions comprise at least... | 07/26/2007 |
| 20070172890 | MAGNETIC ROTATION TO IMPROVE SIGNAL-OVER-BACKGROUND IN BIOSENSING The invention provides a method and a device (10) for distinguishing a specific binding from a less specific binding between at least one magnetic nanoparticle (11) and a surface of another entity by applying a magnetic field and detecting a physical param... | 07/26/2007 |
| 20070159325 | Methodology and Apparatus for the Detection of Biological Substances A methodology and an apparatus for the detection of biological substances employing the integration of multiple functions and units designed into and implemented in the form of an individual silicon chip, described as a sensor unit. The deployment of a set of sensor uni... | 07/12/2007 |
| 20070160984 | Multiple-property composite beads and preparation and use thereof This invention relates generally to the field of moiety or molecule isolation, detection and manipulation and library synthesis. In particular, the invention provides a bead, which bead comprises: a) a magnetizable substance; and b) an electrically conductive substance ... | 07/12/2007 |
| 20070155024 | Method and device for selectively detecting ferromagnetic or superparamagnetic particles. The invention relates to a method for selectively detecting and/or quantifying superparamagnetic and/or ferromagnetic particles on analytes. The method is characterized in that a frequency component of magnetic fields (15, 18), which is generated due to the non-l... | 07/05/2007 |
| 20070134814 | Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease Disclosed are methods and compositions for detecting, analyzing and assessing the significance of calcifying nano-particles. The disclosed methods and compositions generally involve detecting one or more proteins present on a calcifying nano-particle. It has been discov... | 06/14/2007 |
| 20070122916 | Methodology and Apparatus for the Detection of Biological Substances A methodology and an apparatus for the detection of biological substances employing the integration of multiple functions and units designed into and implemented in the form of an individual silicon chip, described as a sensor unit. The deployment of a set of sensor uni... | 05/31/2007 |
| 20070111208 | Determination of free fractions The invention relates to methods for the determination of pharmacological properties of substances, such as, e.g., chemical substances. The invention also relates to methods and kits for use in the determination of the free fraction, fu, of pharmaco-logically... | 05/17/2007 |
| 20070105163 | Flow-controlled magnetic particle manipulation Inventive methods and apparatus are useful for collecting magnetic materials in one or more magnetic fields and resuspending the particles into a dispersion medium, and optionally repeating collection/resuspension one or more times in the same or a different medium, by ... | 05/10/2007 |
| 20070099307 | LIGAND CONCENTRATING, LIQUID CRYSTAL BIOSENSOR SYSTEM A method for detecting a ligand is provided. Antibodies to a predetermined ligand are attached to substrates. The substrates are superparamagnetic, dyed beads. The beads are exposed to an electromagnetic field to immobilize the beads. The beads are contacted with a samp... | 05/03/2007 |
| 20070087453 | Immuno conjugate and process for preparation thereof Present invention deals with a new immuno-reagent comprising hapten (MPAD)-protein-gold for pesticides detection. The conjugate MPAD-protein-gold competes with the analyte of interest for a finite number of binding sites provided by anti-atrazine antibodies coated on ni... | 04/19/2007 |
| 20070087385 | Spherical and magnetical silicagel carriers having an increase surface for purifying nucleic acids The invention relates to spherical and magnetic silicagel particles which are provided with an increased surface by incorporating SiO2 colloids and produced by a method for inverse dispersion cross-linking of silica sols. The addition of certain metallic oxid... | 04/19/2007 |
