...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Application No. | Application Title | Issue Date |
| 20110195478 | BLADDER CANCER BIOMARKER AND TEST METHOD USING THE SAME The present invention discloses a bladder cancer biomarker and a test method using the same. The biomarker contains at least one of the mentioned 69 compounds, such as apolipoprotein A1 (APOA1), apolipoprotein A2 (APOA2), peroxiredoxin 2 (PRDX2), heparin cofactor 2 prec... | 08/11/2011 |
| 20100303832 | GENES AND POLYMORPHISMS ASSOCIATED WITH AMD The invention relates to genes, gene polymorphisms, and genetic profiles associated with an elevated or a reduced risk of alternative complement cascade deregulation disease such as AMD. The invention provides methods and reagents for determination of risk, diagnosis an... | 12/02/2010 |
| 20100135988 | Methods for identifying agents for preventing or treating proliferative diseases, and for inhibiting extracellular matrix or alpha1 type IV collagen A method of detecting proliferative diseases causing sclerosis, comprising measuring the expression of at least one substance selected from the group consisting of STAT3, phosphorylated STAT3, Smad1, phosphorylated Smad1, activin receptor-like kinase 1, activin receptor... | 06/03/2010 |
| 20090181472 | LABELED MOLECULE FOR PROGNOSING TUMOR GRADE OF HEAD NECK CANCER AND METHOD FOR THE SAME The present invention discloses a labeled molecule for prognosing the tumor grade of head neck cancer and a method for the same, wherein a 78-kDA glucose regulated protein (GRP78) is adopted as a labeled molecule of head neck cancer. GRP78 is much more overexpressed in ... | 07/16/2009 |
| 20090081345 | Identification of Prion Proteins in Milk The present invention relates to the use of milk or a derivative thereof for identifying prion proteins, preferably PrPSc prion proteins, in a mammal. The present invention is also directed to a method for identifying prion proteins, preferably PrPSc 03/26/2009 | |
| 20080220459 | Diagnosis of collagen IX destruction A method for detecting or monitoring the presence of protein fragments, cleaved at novel cleaving sites near the N-terminal part of the collagen IX alpha 1 chain, close to the C-terminal part of the NC4 domain, and at the COL3 domain close to the NC3 domain. Neoepitope ... | 09/11/2008 |
| 20080113451 | Method of Labeling with Use of Rare Earth Fluorescent Complex and Method of Analyzing and Detecting A relatively simple and easy method of laveling in which a sample used in electrophoresis technology is labeled with the use of rare earth fluorescent complex DTBTA-Eu3+ as a labeling agent so as to exhibit a fluorescence intensity being stable without depend... | 05/15/2008 |
| 20070275481 | Methods For Detecting Half-Antibodies Using Chip Based Gel Electophoresis The invention provides a method of using chip-based gel electrophoresis to determine the presence of polypeptides with selected disulfide linkage patterns, for example, completely formed tetrameric antibodies as compared to incompletely formed heterodimeric half-antibod... | 11/29/2007 |
| 20070238717 | Neuroprotection with Beta-Lactam Compounds Described herein are methods of treating or preventing neurological disease and disease symptoms using beta-lactam compounds, and compounds useful for treating disease and disease symptoms. ... | 10/11/2007 |
| 20060030055 | Methods and kits for separation and detection of proteins in biological samples Methods and kits are provided for separating a mixture of proteins in a biological sample. Methods for detecting and profiling proteins in biological samples by the separation method and kits are also provided. These methods are particularly useful in assessing damage t... | 02/09/2006 |
| 20050208678 | Anti-fusion assay Methods of identifying a fusion inhibitor and inhibitors of gp41-mediated membrane fusion are disclosed. The methods comprise, for example, providing a first helical polypeptide comprising a sequence of IQN17 (SEQ ID NO: 1); providing a second helical polypeptide of 34 ... | 09/22/2005 |
| 20050176157 | Methods for detecting half-antibodies using chip-based gel electrophoresis The invention provides a method of using chip-based gel electrophoresis to determine the presence of polypeptides with selected disulfide linkage patterns, for example, completely formed tetrameric antibodies as compared to incompletely formed heterodimeric half-antibod... | 08/11/2005 |
| 20050153344 | Method and devices for running reactions on a target plate for MALDI mass spectrometry A peptide or protein microassay method and apparatus in which a wide variety of chromogenic or fluorogenic peptide or protein substrates of interest are individually suspended or dissolved in a hydrophilic carrier, with aliquots of each substrate being deposited in an a... | 07/14/2005 |
| 20050079519 | Electrophoretic analysis of molecules using immobilized probes Methods of detecting target molecules using electrophoresis and media containing immobilized capture are described. ... | 04/14/2005 |