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Class 436/514 - INVOLVING DIFFUSION OR MIGRATION OF ANTIGEN OR ANTIBODY


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Subject matter in which the antigen or antibody migrates
No. of applications: 244
Last issue date: 09/22/2011


1              
Application No.Application TitleIssue Date
20110229913Method for Amplification of Signal in Immunochromatographic Assay and Immunochromatographic Kit Using the Method
The present invention relates to a method for amplifying a signal in an immunochro-matographic assay for high-sensitivity detection of an analyte and an immunochromatographic kit using the method, which amplifies a signal by controlling a flow rate by discrimination bet...
09/22/2011
20110201131ANTIBODY DETECTION METHOD INVOLVING OLIGONUCLEOTIDE ENHANCED COLLOIDAL GOLD SIGNAL
The present invention refers to a rapid immunochromatographic test device for antibody detection, comprising at least a first and a second conjugate releasing pad, wherein the first conjugate pad comprises a gold conjugated protein linked first oligonucleotide and a gol...
08/18/2011
20110195525Method of use and Apparatus for an Enhanced Lateral Flow Rapid Test Device
An immunoassay test membrane strip that is able to quickly tell the experimenting user the results of the presence of a specific antibody. The present invention makes use of a membrane strip that is broken into different sections. The user applies a specimen and a dilut...
08/11/2011
20110151549Device For Carrying Out An Individual Immunoassay In A Fully Automatic Manner
The invention relates to a device for carrying out an individual immunoassay in a fully automatic manner in order to detect the presence of a biologically active substance in a sample, and to the use of one such device. The invention also relates to a sample strip which...
06/23/2011
20110053291METHOD FOR ANALYZING SAMPLE SOLUTION AND APPARATUS FOR ANALYZING SAMPLE SOLUTION
Disclosed is a method for analyzing a sample solution, including introducing a sample solution 50 through a sample introduction part 6 and developing the sample solution 50 to a developing layer 2 through a capillary phenomenon to analyze an ...
03/03/2011
20100267167DEVICE FOR DETECTION OF MOLECULES IN BIOLOGICAL FLUIDS
Disclosed is a test device and a method for qualitatively and/or quantitatively measuring the concentration of an analyte in a biological fluid sample. The test device includes a housing defining a sample port, a test well containing a stirrer and a conjugate, and a tes...
10/21/2010
20100267166DIAGNOSTIC DETECTION DEVICE
The invention comprises a device for detecting an analyte in a liquid sample deposited on a first portion of the device for transport to a second portion of the device that is in fluid contact with the first portion. In specific embodiments, the device comprises a label...
10/21/2010
20100216158DIAGNOSTIC TEST FOR HEAD AND FACIAL PAIN
A diagnostic test for a head and facial pain disorder in a human patient includes providing test strip containing one or more antibodies corresponding one or more biological markers associated with the disorder or with multiple disorders. A saliva sample is collected fr...
08/26/2010
20100190268Assay Device, System and Method
A system for treating a blood sample (700) having an analyte of interest comprises a strip (200) having a membrane (218), respective portions (216, 220 and 222, or 300) which are provided for receiving the sample, for lysing cel...
07/29/2010
20100167264Quantitative analyte assay device and method
The present invention relates to an assay device and a method for using such for the quantitative determination of an analyte, based on a test strip, which contains a porous test membrane allowing for capillary flow of the analyte and complexes of the analyte, a porous ...
07/01/2010
20100112597Methods for Quantifying Protein Leakage From Protein Based Affinity Chromatography Resins
The present invention provides methods of quantifying protein leakage from a protein based affinity chromatography media (e.g., protein A, protein G and protein L based affinity chromatography media), where such a protein is used for isolating and/or removing a molecule...
05/06/2010
20100068727RAPID IMMUNOCHROMATOGRAPHIC DETECTION BY AMPLIFICATION OF THE COLLOIDAL GOLD SIGNAL
The present invention relates to a method for rapid immunochromatographic detection of a target in a sample by double sandwich immunoassay detection, wherein the target is an antibody and/or an antigen, using different colloidal gold conjugates conjugated with a first a...
03/18/2010
20100062543Polyelectrolytic Internal Calibration System of a Flow-Through Assay
A flow-through assay for detecting the quantity of an analyte residing in a test sample is provided. The flow-through assay contains a porous membrane that is in fluid communication with probe conjugates that contain a specific binding member and a detectable probe. The...
03/11/2010
20100055721Surface Enhanced Raman Scattering and Multiplexed Diagnostic Assays
Multiplexed lateral flow assays, related methods, and devices are disclosed which are capable of simultaneously detecting multiple analytes. The assays are preferably immunoassays and can be multiplexed spatially, spectrally, and both spatially and spectrally. Multiplex...
03/04/2010
20100029014Micromachined diagnostic device with controlled flow of fluid and reaction
This invention relates to a micromachined microfluidics diagnostic device that comprises one or multiple assaying channels each of which is comprised a sample port, a first valve, a reaction chamber, a second valve, a fluid ejector array, a third valve, a buffer chamber...
02/04/2010
20100015634IN SITU LYSIS OF CELLS IN LATERAL FLOW IMMUNOASSAYS
Devices and methods incorporate lysis agents into a point-of-care testing device. The sample is loaded, and then the sample travels until it encounters a lysis agent. The lysis agent is preferably pre-loaded onto the collection device. In a preferred embodiment, the ini...
01/21/2010
20090280576Analyte assaying by means of immunochromatography with lateral migration
The invention relates to a device for determining an analyte in a liquid sample. The inventive device consists of: a capillary action means, involving lateral migration, defining a reference capillary action direction and comprising a liquid sample deposit area and an a...
11/12/2009
20090269857Instruments for detecting low-molecular weight substance
To provide the following instruments 1 and 2 as a low-molecular-weight substance detection instrument employing immunochromatography capable of detecting conveniently and sensitively detecting a low-molecular weight substance such as an environmental pollutant (e.g., a ...
10/29/2009
20090258439IMMUNOCHROMATOASSAY METHOD AND IMMUNOCHROMATOASSAY KIT
An immunochromatoassay method that allows high detection sensitivity measurement. The method including the steps of: permeating an analyte solution that includes a visibly labeled second binding substance that specifically binds to a detection target substance into a te...
10/15/2009
20090253219POSITIVE DETECTION LATERAL-FLOW APPARATUS AND METHOD FOR SMALL AND LARGE ANALYTES
Methods and devices for the detection and/or quantification of an analyte in a sample are provided. These are positive detection methods and devices, in that the more analyte is present in the sample, the stronger the signal that is provided. Devices of the invention in...
10/08/2009
20090246885Media for affinity chromatography
The invention relates generally to solid supports for chromatography. In specific embodiments the invention provides for solid supports suitable for affinity chromatography along with methods, systems and kits which use the same....
10/01/2009
20090215199Caffeine Detection Via Internally-Referenced Two Part Assay
Methods, compositions, and apparatus for detecting the presence of caffeine in a liquid sample are provided. In certain embodiments, an internally referenced competitive assay allows a very precise determination of a threshold value of caffeine for use in semiquantitati...
08/27/2009
20090181470MEASUREMENT KIT AND AN IMMUNOCHROMATOGRAPHY METHOD
It is an object of the present invention to provide a measurement kit for developing a first developing solution and a second developing solution from different directions to suppress background noise, and an immunochromatography kit. The present invention provides a me...
07/16/2009
20090181471ASSAY DEVICE AND PROCESS FOR THE TESTING OF FLUID SAMPLES
An assay device for testing of liquid samples for drugs of abuse has a transparent container for retaining a liquid sample. A backing member is within the container and is curved so that its front surface corresponds to the curvature of the container wall. Immunoassay t...
07/16/2009
20090170072DEVICE FOR COLLECTION AND ASSAY OF ORAL FLUIDS
A device for collecting and transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. The lateral chromatographic strip is placed within and extend along a cavity defined in a housing. At least one inspection site to the l...
07/02/2009
20090162833TEST DEVICE FOR RAPID DIAGNOSTICS
Devices for detecting analytes or analogues thereof in a biological sample are disclosed. The device includes a solid support. The solid support has several juxtaposed zones. The sample is able to migrate from a sample receiving zone towards a detection zone. The analyt...
06/25/2009
20090017561Labelled silica nanoparticles for immunochromatographic reagent, immunochromatographic reagent, immunochromatographic test strip using the same, and immunochromatographic fluorescence-detecting system or radiation-detecting system
Labelled silica nanoparticles for immunochromatographic reagent, comprising silica nanoparticles containing a labelled substance....
01/15/2009
20080286881COMPOSITIONS AND METHODS FOR COMBINING REPORT ANTIBODIES
Compositions are disclosed. One embodiment of a composition comprises a first antibody having an affinity for an antigen and a second antibody having an affinity for the first antibody, wherein at least one antibody is conjugated to a marker, and wherein the antigen is ...
11/20/2008
20080254444Immunoassay Devices and Use Thereof
An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site with immobilized antigen or antibody for the ligand to be tested, and a ...
10/16/2008
20080241962Micromachined Diagnostic Device with Controlled Flow of Fluid and Reaction
This invention relates to a micromachined microfluidics diagnostic device that comprises one or multiple assaying channels each of which is comprised a sample port, a first valve, a reaction chamber, a second valve, a fluid ejector array, a third valve, a buffer chamber...
10/02/2008
20080171399Forensic Test for Human Blood
A lateral flow test strip for the definitive detection of human blood from forensic samples derived from crime scenes, sexual assault evidence kits, and other sources of forensic evidence....
07/17/2008
20080102537METHOD OF DETECTING ANALYTES IN A MICROFLUIDIC SAMPLE AND A SYSTEM FOR PERFORMING THE SAME
A method of detecting analytes in a microfluidic sample includes introducing at least one type of analyte, at least one type of carrier particle, and a fluid into a mixing chamber of a system. The at least one type of analyte binds to a site on the at least one type of ...
05/01/2008
20080096233Isolation Of Immune Complexes
The present invention provides methods of detecting and/or isolating immune complexes. The antigen in the immune complexes can further be isolated from the immune complexes to facilitate research and characterization of the antigen. Other embodiments of the present inve...
04/24/2008
20080085525Chromatographic Analysis Devices And Test Kits
Chromatographic analysis devices (1) are described for the detection of blood parameters, consisting of cell components of cells circulating in blood of human or animal origin, or of plasma components, in a sample of a bodily fluid containing such cells, comprisi...
04/10/2008
20080076169Lateral flow strip assay
A lateral flow strip assay apparatus comprising a housing; a lateral flow strip in the housing, the lateral flow strip having a receiving portion; a sample collection unit; and a reagent reservoir. Saliva and/or buccal cells are collected from an individual using the sa...
03/27/2008
20080070323OPTICAL MICROSCOPY WITH PHOTOTRANSFORMABLE OPTICAL LABELS
An apparatus includes a position-sensitive detector to detect intensities of radiation as a function of position on the detector, and an optical system, characterized by a diffraction-limited resolution volume, adapted for imaging light emitted from activated and excite...
03/20/2008
20080070322OPTICAL MICROSCOPY WITH PHOTOTRANSFORMABLE OPTICAL LABELS
First activation radiation is provided to a sample that includes fluorescent proteins (“FPs”) to activate a first subset of the FPs in the sample. First excitation radiation is provided to the first subset of FPs in the sample to excite at least some of the activate...
03/20/2008
20080064120Raman spectroscopic lateral flow test strip assays
The invention provides improved Raman spectroscopy-based methods and systems for the quantitative analysis of selected analytes using lateral flow binding assay test strips. ...
03/13/2008
20080064119Rapid diagnostic test systems and methods
A rapid diagnostic test system includes a lateral-flow strip for performing a binding assay. The lateral-flow strip contains a binding agent having a deposition density that varies periodically along at least a portion of the lateral-flow strip. The test system further ...
03/13/2008
20080044927MEDICAL TEST STRIP
A test strip comprises a substrate having a long and narrow rectangular shape and the substrate having no hole thereon; a first sample-collection pad adhered to one side of the substrate, the first sample-collection pad having a side notch; the notch and the substrate b...
02/21/2008
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