Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Application No. | Application Title | Issue Date |
| 20120045838 | CUSTOMIZED MOLECULARLY IMPRINTED POLYMER (MIP) UNITS A method of manufacturing at least one customized MIP unit including: (a) providing at least one MIP unit having a surface including at least one target binding site configured to resemble a target molecule and surface-bound chargeable groups; (b) contacting the MIP uni... | 02/23/2012 |
| 20110207229 | METHOD AND DEVICE FOR DETERMINING THE AMOUNT OF MAGNETICALLY LABELED TARGET COMPONENTS The invention relates to a method and a device (100) for determining the amount of a target component (2) in a sample, wherein magnetic particles (2) can bind to a contact surface (4) with kinetics that depend on the sample-amount of the tar... | 08/25/2011 |
| 20110195434 | METHOD FOR THE ANALYSIS OF SOLID OBJECTS A method of analysis or diagnosis of solid objects is based on real-time detection of how predefined probes interact with structures present on or in the solid object combined with the calculation of how the recorded binding curves of said probes are distributed in term... | 08/11/2011 |
| 20110183422 | MEASUREMENT OF CURING A method for increasing productivity and quality in production of cured polymer by a real time measurement of the progress of curing, in a mould cavity, which being filled with a compound to be cured, wherein a signal is generated by a wave at an ultrasonic or equivalen... | 07/28/2011 |
| 20110171668 | Determination Of Equilibrium Constants In Solution By Multi-Step Kinetics The invention relates to a method for determining a first equilibrium constant of a first equilibrium reaction via MSK analysis of a second equilibrium reaction, whereby the first and the second equilibrium reaction share at least one reactant.... | 07/14/2011 |
| 20110091904 | METHOD FOR DETERMINATION OF AFFINITY AND KINETIC CONSTANTS The invention is related to a method for quantification of a first dissociation equilibrium constant Kd1 for a complex AB between interactants A and B relative to a second dissociation equilibrium constant Kd2 for a complex CD between interactants ... | 04/21/2011 |
| 20100323449 | HIGH THROUGHPUT CATALYTIC PROCESS DEVELOPMENT METHOD A method for investigating longitudinally dependent properties of the composite catalyst bed of a laboratory scale plug flow reactor, comprises the steps of: supplying fresh reactant feed to the inlet of said composite catalyst bed; sampling and measuring the amounts of... | 12/23/2010 |
| 20100136697 | APPARATUS AND METHOD OF MEASURING CONCENTRATION OF FUEL An apparatus of measuring concentration of fuel including a catalyst layer, a diffusion layer, a fuel chamber, a reactive gas chamber, and a sensor is provided. The diffusion layer is connected to the catalyst layer. The fuel chamber is suitable for containing a fuel. T... | 06/03/2010 |
| 20100041082 | METHODS FOR DETERMINING THE METABOLISM OF SUGARS AND FATS IN AN INDIVIDUAL Provided herein are methods for determining the metabolism of one or more sugars and/or fatty acids, and applications thereof. Such applications include determining the rate of glycogen synthesis and glycolysis, which are believed to be early markers for predicting elev... | 02/18/2010 |
| 20100028372 | STABILIZATION OF AQUEOUS COMPOSITIONS OF PROTEINS WITH DISPLACEMENT BUFFERS An aqueous composition having increased protein stability is obtained by: a. determining a pH at which the protein has stability at the desired temperature; b. adding to the composition at least one displacement buffer wherein the displacement buffer has a pKa that is a... | 02/04/2010 |
| 20100022008 | COMPOSITIONS AND METHODS FOR DETECTING NERVE AGENTS The present invention provides methods and compositions for detecting, identifying and measuring the abundance of chemical nerve agents. Methods and compositions of the present invention are capable of providing selective detection of phosphorous based nerve agents, suc... | 01/28/2010 |
| 20090317922 | USE OF ADDITIVES TO LOWER THE RATE OF A BINDING REACTION A method of lowering the rate of a specific binding reaction in an assay for the detection and/or measurement of an analyte of interest is provided herein. In particular, the method includes providing a fluorescent conjugate of the analyte; a component capable of specif... | 12/24/2009 |
| 20090305424 | Microfluidic Flow Devices For Determining Parameters of Physical and/or Chemical Transformations Microfluidic flow devices for determining parameters of a physical and/or chemical transformation include a body (2), at least one flow microchannel (36) for transferring a mixture (G; T′) of at least two components, such microchannel being formed within... | 12/10/2009 |
| 20090191637 | Method and apparatus for determining anticoagulant therapy factors Methods and apparatus are disclosed for determining a new anticoagulant therapy factors for monitoring oral anticoagulant therapy to help prevent excessive bleeding or deleterious blood clots that might otherwise occur before, during or after surgery. New anticoagulant ... | 07/30/2009 |
| 20090142846 | METHODS FOR MEASURING BIOCHEMICAL REACTIONS Methods for measuring biochemical reactions and analysis of reaction products by controlling dispersion of reagents within fluid streams such that the measuring of the biochemical reaction is substantially free of a measurable dispersion artifact. Controlling dispersion... | 06/04/2009 |
| 20090137063 | METHOD FOR DETERMINING THE QUALITY OF A BIOLOGICAL SAMPLE The present invention relates to a method of determining the quality of a biological sample. A method according to the invention may be used to determine if a biological sample is suitable to use in a further biological assay demanding samples of good quality to render ... | 05/28/2009 |
| 20080273206 | Biomimetic Mineralization Method and System Disclosed are methods and systems that can be quickly and efficiently utilized to examine the kinetics of a growth and development protocol in a controlled environment, for instance in vivo. Disclosed systems can include a synthetic mineralization complex that can nucle... | 11/06/2008 |
| 20080261254 | Procedure for the determination of the reaction lag phase in an analyte-dependent reaction The invention is in the field of analytical technique and relates to an improved procedure for determining the concentration or activity of an analyte, an analyte-dependent detection reaction being set in motion and the reaction kinetics determined being evaluated. The ... | 10/23/2008 |
| 20080227206 | METHOD AND SYSTEM FOR DETERMINATION OF MOLECULAR INTERACTION PARAMETERS A method of determining kinetic parameters for a reversible molecular interaction between a ligand immobilized to a solid support surface and a binding partner to the ligand in solution, comprises sequentially, without intermediate regeneration or renewal of the immobil... | 09/18/2008 |
| 20080221033 | Monitoring of Cardiac Natriuretic Peptides During Diagnosis, Management, and Treatment of Cardiac Diseases In a cardiac monitoring method, at east an inactive natriuretic peptide (22) and an active natriuretic peptide (20) are assayed in a biological sample taken from a patient. Both the inactive and active natriuretic peptides are produced in the patient respo... | 09/11/2008 |
| 20080206876 | INSTRUMENTS FOR THE SELECTIVE AND DIRECT DETECTION OF FREE METALS IN FLUIDS AND METHODS TO DIAGNOSE METAL-RELATED DISEASES AND DETERMINE PHARMACOLOGIC DOSING REGIMENS Instruments for the selective and direct detection of free metals in fluids and methods to diagnose metal-related diseases and determine pharmacologic dosing regimens are disclosed.... | 08/28/2008 |
| 20080160548 | Microoptical Detection System and Method for Determination of Temperature-Dependent Parameters of Analytes The invention relates to a microoptical detection system and a method for detecting analytes by means of time-resolved luminescence. This serves for determination of temperature-dependent parameters of analytes, in particular for determination of point mutations of nucl... | 07/03/2008 |
| 20080057587 | FAST METABOLIC IMAGING OF SYSTEMS WITH SPARSE SPECTRA USING SPIRAL CSI A method of imaging the individual components of systems with sparse spectra using magnetic resonance imaging including the steps of a) exciting nuclei of labeled components using a MRI pulse sequence, b) selecting a proper spectral window to avoid/minimize signal overl... | 03/06/2008 |
| 20080020468 | Pharmaceutical Analysis Apparatus and Method An apparatus and method are provided for analyzing the release of active agent(s) from pharmaceutical and pharmaceutical-like products. The apparatus and method provide for more accurate simulation of the conditions in the GI tract including forces that are applied to t... | 01/24/2008 |
| 20070298503 | ANALYZING TRASLATIONAL KINETICS USING GRAPHICAL DISPLAYS OF TRANSLATIONAL KINETICS VALUES OF CODON PAIRS Graphical displays are provided of translational kinetics values of codon pairs in a host organism plotted as a function of polypeptide-encoding nucleotide sequence. Such translational kinetics values of codon pair frequencies correspond to the predicted translational p... | 12/27/2007 |
| 20070292958 | Apparatuses and methods for monitoring enzymatic reactions The present invention relates to apparatuses and methods for analyzing enzyme reactions, including, large, industrial-scale reactions. The methods allow for enzymatic reaction to be followed on-line in real-time, without the need for sample removal and without contamina... | 12/20/2007 |
| 20070281329 | Characterization of individual polymer molecules based on monomer-interface interactions The invention relates to a method for detecting a double-stranded region in a nucleic acid by (1) providing two separate, adjacent pools of a medium and a interface between the two pools, the interface having a channel so dimensioned as to allow sequential monomer-by-mo... | 12/06/2007 |
| 20070196923 | Method Of Checking The Hermeticity Of A Closed Cavity Of A Micrometric Component And Micrometric Component For The Implementation Of Same In order to check the hermeticity of a closed cavity of at least one micrometric component, said component includes a structure made over or in one portion of a substrate, a cap fixed to one zone of the substrate to protect the structure, and an indicator element whose ... | 08/23/2007 |
| 20070196924 | APPARATUS AND METHOD TO MEASURE THE KINETICS PARAMETERS OF A POROUS POWDER CATALYST An apparatus and method are disclosed for measuring the kinetic parameters of a catalyst powder, which include the reaction rate constants, active site concentration and intraparticle diffusivity. The measurement of the active site concentration selectively measures jus... | 08/23/2007 |
| 20070037285 | Method and supply unit for monitoring changes and states in reaction chambers The invention relates to a method for monitoring changes and states in reaction chambers as well as a supply unit which is used for introducing a liquid culture medium during cell culture analyses. The aim of the invention is to allow for an air bubble-free measurement ... | 02/15/2007 |
| 20060239898 | Methods for measuring growth rates of carbon nanotubes A method for measuring a growth rate of a carbon nanotube includes the following steps: (a) providing a substrate (12); (b) forming a catalyst layer on the substrate; (c) heating the substrate to a predetermined temperature; (d) intermittently introducing/providi... | 10/26/2006 |
| 20060234381 | SYSTEM AND METHOD FOR DETERMINING OPTIMAL REACTION PARAMETERS USING CONTINUOUSLY RUNNING PROCESS A reaction system enables a plurality of optimization experiments for a reaction to be performed continuously, to enable optimal reaction parameters to be determined. Dilution pumps are included to automatically vary the solvent mixed with reactants so a concentration o... | 10/19/2006 |
| 20060073599 | Microfabricated diffusion-based chemical sensor A channel-cell system is provided for detecting the presence and/or measuring the presence of analyte particles in a sample stream comprising: a) a laminar flow channel; b) two inlet means in fluid connection with said laminar flow channel for respectively conducting in... | 04/06/2006 |
| 20050287673 | Reactor mixing Immiscible substances, such as gases, solids or liquids may be included within a reaction site container as a mixer of a liquid sample. Movement of the mixer within the container may help suspend or re-suspend cells or other species. Movement of the mixer also may gener... | 12/29/2005 |
| 20050272159 | DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid. ... | 12/08/2005 |
| 20050244975 | Method for monitoring a polymerization in a three-dimensional sample A method of optical infrared thermography, and the use thereof in monitoring and characterizing the polymerization of the three dimensional sample is described. ... | 11/03/2005 |
| 20050136544 | Osmotic reaction detector for monitoring biological and non-biological reactions A method and apparatus for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes of reaction detector. The reaction detector is capable of measuring the small changes in pressure that occur du... | 06/23/2005 |
| 20050136543 | Osmotic reaction detector for monitoring biological and non-biological reactions A method and apparatus for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes in a reaction cell. The reaction cell is capable of measuring the small changes in pressure that occur due to o... | 06/23/2005 |
| 20050130309 | Detection of silanol groups on a surface Methods and reagents for the detection and/or quantification of silanol groups on a silica surface are provided. In certain embodiments, the subject methods are used to evaluate the channel surface of a silica capillary tubing. This evaluation can facilitate methods for... | 06/16/2005 |
| 20050101028 | Method of judging homogenization/reaction completion and method of measuring solution concentration using the same It is intended to provide a method for determining homogenization and/or reaction completion, capable of making the measurement time necessary and sufficient and enhancing the measurement speed, and a method for measuring solution concentration using the same. According... | 05/12/2005 |
