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Patent No. 6650315

Mouse device with a built-in printer

A mouse device for use as an input device of a computer is provided that includes a housing in which recording paper is loadable, and a printer unit provided within the housing for printing on the recording paper print information received from the computer.

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Class 435/7.9 - Assay in which an enzyme present is a label


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter in which an enzyme present is a label in
No. of applications: 376
Last issue date: 05/24/2012


1                    
Application No.Application TitleIssue Date
20120129188CIRCULATING CYTOCHROME C AS BIOMARKER OF REPERFUSION INJURY AND RESPONSIVENESS TO MITOCHONDRIAL TARGETED INTERVENTIONS
The present invention relates generally to the use of circulating cytochrome c as a biomarker of reperfusion injury that results from whole body ischemia. Circulating levels of cytochrome c can be used as predictor of survival rates and to assess the effects of interven...
05/24/2012
20120128642POTENCY MARKERS
Methods for identifying trichogenic dermal cells, including dermal papilla cells and dermal sheath cells, capable of inducing hair follicle formation when injected into skin are provided. Biomarkers have been discovered that can be used to detect, identify, and distingu...
05/24/2012
20120129168TUMOR MARKER AND USE THEREOF
The present invention detects SNX5 in a sample from a subject. The SNX5 is used as a tumor marker specific to papillary thyroid carcinoma, whereby diagnosis of papillary thyroid carcinoma is carried out easily. The present invention provides also a technique of discrimi...
05/24/2012
20120107335Synthetic Oligopeptides Designed From Mite Cysteine Proteases and Methods for the Production of
The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Der...
05/03/2012
20120082618PROSTATE CANCER DIAGNOSIS AND TREATMENT
The present invention relates to novel antibodies and their use for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastasis thereof. The present invention also relates to novel pharmaceutical compositions for the treatment of prostate ...
04/05/2012
20120070837CIP2A as a biomarker in detection of cervical cancer
The present invention provides methods and compositions for detecting cervical cancer in a human. The present invention provides CIP2A as a biomarker detectable in a biological sample from cervix of an individual, an increased expression of same is an indication of cerv...
03/22/2012
20120052079Compositions, Kits, and Methods for Predicting Anti-Cancer Response to Anthracyclines
The present invention is based, in part, on the discovery that amplification of human chromosome 8q22-23 regions and over-expression of 8q22-23 genes (e.g., LAPTM4B and YWHAZ) is associated with and predictive of resistance to anthracycline-type chemotherapy. Accordingl...
03/01/2012
20120052512METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one...
03/01/2012
20120046186Gene Expression Markers for Prediction of Response to Platinum-Based Chemotherapy Drugs
The present invention provides methods for predicting a likelihood that a patient with cancer will exhibit a positive response to a treatment with a platinum-based chemotherapy drug. The methods generally involve determining an expression level of a gene product that co...
02/23/2012
20120045776MONOCLONAL ANTIBODY DS6, TUMOR-ASSOCIATED ANTIGEN CA6, AND METHODS OF USE THEREOF
The present application describes a monoclonal antibody selected from the group consisting of monoclonal antibody DS6, monoclonal antibodies that specifically bind to the antigen or epitope bound by monoclonal antibody DS6, and fragments of the foregoing that specifical...
02/23/2012
20120040852BIOMARKERS
The present invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorders...
02/16/2012
20120039868Biomarkers for Graft Rejection
Methods are disclosed for diagnosing rejection in a transplanted subject, monitoring rejection in a transplanted subject at risk thereof, preventing, inhibiting, reducing or treating rejection in a transplanted subject, or identifying agents for use in the prevention, i...
02/16/2012
20120035069PROGNOSIS OF BREAST CANCER PATIENTS BY MONITORING THE EXPRESSION OF TWO GENES
The present invention relates to the expression of two genes, CyclinG2 and Sharp1, which correlates with prognosis in individuals having breast cancer. Specifically, this invention provides a method to stratify samples from breast cancer patients in a high or low recurr...
02/09/2012
20120027770NOVEL CELL AND THERAPEUTICAL AND DIAGNOSTICAL METHODS BASED THEREON
The invention relates to a novel cell derived from the human body, where said cell comprises a Clever-1 receptor; to a method for affecting the immune system of an individual and for treatment of diseases or conditions related to the function of the immune system and to...
02/02/2012
20120028281INHIBITION OF MIGRATION INHIBITORY FACTOR IN THE TREATMENT OF DISEASES INVOLVING CYTOKINE-MEDIATED TOXICITY
The present invention relates to diagnostic methods for determining migration inhibitory factor (MIF) mRNA content in a sample, wherein MIF is human MIF polypeptide having a molecular weight of approximately 12.5 kDa and kits for detecting MIF....
02/02/2012
20120029079PHARMACEUTICAL COMPOSITIONS CONTAINING FLUORINATED OR PERFLUORINATED CARBOXYLIC ACIDS
The molecules of formula (I) are useful in treating diabetes, obesity, hypercholesterolaemia, hyperlipidaemia, cancer, inflammation or other conditions in which modulation of lipis of eicosanoid status or functions may be desirable. Formula (I): Z1—Z1<...
02/02/2012
20120028836USE OF PROTEIN SATB2 AS A MARKER FOR COLORECTAL CANCER
The invention provides new methods, means and uses in connection with detection, characterization and prognosis of colo-rectal cancer, via the identification of the SATB2 protein as a marker for this cancer type....
02/02/2012
20120021416BIOLAYER INTERFEROMETRY MEASUREMENT OF BIOLOGICAL TARGETS
Disclosed are methods and compositions for the ultrasensitive detection of oligonucleotides, proteins, protein complexes, biomolecules, and infectious agents using a peroxidase driven deposition of substrates onto interferometry capable biosensors, coupled to the specif...
01/26/2012
20120022500Compositions and Methods for Induced Brown Fat Differentiation
The invention provides methods and compositions for inducing brown fat cell differentiation through modulation of both Prdm1β and C/EBPβ activity and/or expression. Also provided are methods for preventing or treating obesity or an obesity related disorder in a subjec...
01/26/2012
20120021439SERIAL MULTIPLE ANTIGEN COLOCALIZATION IN PARAFFIN-EMBEDDED TISSUE
The present invention provides a novel method called Sequential IMmunoPeroxidase Labeling and Erasing (SIMPLE) that enables the simultaneous visualization of at least five markers within a single tissue section. Utilizing the alcohol-soluble peroxidase substrate 3-amino...
01/26/2012
20120021925DIAGNOSTIC ASSAYS FOR PROSTATE CANCER USING PSP94 AND PSA BIOMARKERS
The application refers to a method for diagnosing prostate cancer through the measurement of the combination of PSP94 (β-microseminoprotein) and F/T PSA biomarkers, the method using urine samples to measure PSP94 and serum samples to analyse F/T PSA. In one embodiment,...
01/26/2012
20120021438Method of Detecting Target, Method of Suppressing Increase in Background and Detection Apparatus
Provided are a method of detecting a target with high accuracy, a method of suppressing an increase in background, and a detection apparatus.

A first target-binding substance that is immobilized at a carrier and is capable of binding to a t...

01/26/2012
20120020972ANTIBODIES RELATING TO PIVKA-II AND USES THEREOF
The present disclosure relates to antibodies and immunoassay methods for use in the diagnosis, treatment and prevention of hepatocellular carcinoma (HCC), liver cancer and related conditions....
01/26/2012
20120021437TETRANOR-PGDM/PGJM SPECIFIC IMMUNOGENS, ANTIBODIES, TRACERS, ASSAY KITS AND METHODS FOR MAKING SAME
Tetranor-PGDM/tetranor-PGJM-specific antibodies, immunogens used to generate them, the processes of their manufacture, and their uses in assay kits for detecting and quantifying tetranor-PGDM and tetranor-PGJM in biological fluids for determining biosynthesis of PGD
01/26/2012
20120003209METHODS AND KITS USED IN IDENTIFYING GLIOBLASTOMA
The invention encompasses methods and kits used in the identification of invasive glioblastoma based upon the expression of Akt1, Akt2, and Akt3. The methods and kits also allow prediction of disease outcome and staging of patients with regard to therapy....
01/05/2012
20120003669Immunohistochemical staining method and immunohistochemical staining apparatus
An immunohistochemical staining apparatus for carrying out immunohistochemical staining includes a sample chamber (1) in which a primary sample (s1) comprised of a tissue specimen (t) to which a primary antibody (Ig1) is applied is disposed between ...
01/05/2012
20120003660DIAGNOSIS OR PROGNOSIS OF BREAST CANCER BASED ON EXPRESSION LEVEL OF THIOREDOXIN-1
The present disclosure relates to a diagnostic marker for breast cancer, having thioredoxin-1 as an active ingredient, and to a diagnostic kit for breast cancer using same. The thioredoxin-1 is overexpressed in human breast cancer tissue so as to enable the early diagno...
01/05/2012
20120004190HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediate...
01/05/2012
20110319280ECT2 ONCOGENE AS A THERAPEUTIC TARGET AND PROGNOSTIC INDICATOR FOR LUNG AND ESOPHAGEAL CANCER
The invention features methods for detecting lung cancer or esophageal cancer, by detecting over-expression of ECT2 compared the normal organs. Also disclosed are methods of identifying compounds for treating and preventing lung cancer or esophageal cancer, based on the...
12/29/2011
20110319333METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A k...
12/29/2011
20110318747Nonseparation Assay Methods
Assay methods are disclosed involving specific binding reactions which are simplified compared to known methods. A compound capable of producing chemiluminescence is immobilized on a solid support as is a member of a specific binding pair for capturing an analyte from a...
12/29/2011
20110318729Rapid Bioluminescence Detection Assay
An assay is provided for detecting the activity of a reporter kinase comprising (i) adding said reporter kinase to an assay mixture wherein said reporter kinase is contacted with bioluminescent reagent no more than minutes after being contacted with ADP, and wherein, pr...
12/29/2011
20110318754Reduction in False Results in Assay Measurements
Methods and reagents are disclosed for detecting a false result in an assay measurement for determining a concentration of an analyte in a sample suspected of containing the analyte. The method comprises measuring assay signal resulting from background only and measurin...
12/29/2011
20110318755Universal Testing Platform for Medical Diagnostics
The invention relates to analysis of samples (for example, blood, urine, saliva, or swab). Some embodiments include a diagnostic testing platform. The platform may permit the analysis of a plurality of different samples with no or only minor modifications made to the pl...
12/29/2011
20110318764METHOD FOR DETECTING MUSCLE DEGENERATIVE DISEASES, AND METHOD FOR DETERMINING THERAPEUTIC EFFICACY ON THE DISEASES
Muscle degenerative diseases can be detected in the early stage and the therapeutic efficacy of a therapeutic agent and/or a therapy method for the diseases can be determined by measuring 11,15-dioxo-9α-hydroxy-2,3,4,5-tetranorprostan-1,20-dioic acid (referred to as â€...
12/29/2011
20110311572NUCLEOTIDE AND AMINO ACID SEQUENCES ENCODING AN EXPORTED PROTEIN 1 DERIVED FROM PLASMODIUM VIVAX AND USES THEREOF
The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of Plasmodium vivax, and methods of using these polynucleotides and polypeptides in the detection of P. vivax antibodies or anti-P. vivax antibodies in a su...
12/22/2011
20110311990TETRANOR-PGEM/PGAM SPECIFIC IMMUNOGENS, ANTIBODIES, TRACERS, ASSAY KITS AND METHODS FOR MAKING SAME
Tetranor-PGEM/tetranor-PGAM-specific antibodies, immunogens used to generate them, the processes of their manufacture, and their uses for detecting and quantifying tetranor-PGEM in biological fluids for determining biosynthesis of PGE2 in a subject or patient...
12/22/2011
20110305715ANTIBODIES TO 3-HYDROXYCOTININE AND METHODS OF USE THEREOF
The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to 3-hydroxycotinine (3HC). The invention also provides compositions containing these antibodies and fragments thereof, and to their use in diagnostic and therapeutic applic...
12/15/2011
20110306062Babesia microti genomic clones containing novel antigens useful in the diagnosis of babesios
Disclosed are the cloning and expression of novel antigens in Babesia microti. The recombinant polypeptides are highly immunogenic. The polypeptides of the present invention provide the basis of a diagnostic assay that is sensitive, rapid and accurate using patie...
12/15/2011
20110300557METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY hCG ASSAY
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early preg...
12/08/2011
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