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Patent No. 6205950

Pet Toilet-Like Water Disk and Food Storage

One pet-friendly inventor patented "a device for watering pets, e.g., a dog or cat." The device, he helpfully noted, "has the general shape of a toilet."

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Class 435/7.8 - Involving nonmembrane bound receptor binding or protein binding other than antigen-antibody binding


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter in which the measurement or test includes
No. of applications: 347
Last issue date: 05/24/2012


1                  
Application No.Application TitleIssue Date
20120129183METHODS AND KITS FOR ISOLATING PLACENTAL DERIVED MICROPARTICLES AND USE OF SAME FOR DIAGNOSIS OF FETAL DISORDERS
A prenatal method of analyzing a fetus is disclosed. The method comprising: (a) isolating placental derived microparticles; and (b) analyzing at least one component of the contents of the placental derived microparticles, wherein the at least one component is indicative...
05/24/2012
20120108662COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS
The present application relates to compositions and the treatment of skin disorders, dry skin, protection of skin in inflammatory events and neurological disorders. The present application more particularly discloses the identification of new genes and metabolic pathway...
05/03/2012
20120083006METHODS FOR THE IDENTIFICATION OF KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF KINASE PROTEINS
The present invention relates to immobilization compounds (I), immobilization products and preparations thereof as well as methods and uses for the identification of kinase interacting compounds or for the purification or identification of kinase proteins.

04/05/2012

20120052516METHOD FOR DIAGNOSING A HEMOGLOBIN-RELATED DISORDER
The invention relates to a method for diagnosing, staging and/or monitoring a hemoglobin-related disorder such as β-thalassemia or a treatment against said hemoglobin-related disorder in a subject in need thereof based on the detection and/or quantification the presenc...
03/01/2012
20120029079PHARMACEUTICAL COMPOSITIONS CONTAINING FLUORINATED OR PERFLUORINATED CARBOXYLIC ACIDS
The molecules of formula (I) are useful in treating diabetes, obesity, hypercholesterolaemia, hyperlipidaemia, cancer, inflammation or other conditions in which modulation of lipis of eicosanoid status or functions may be desirable. Formula (I): Z1—Z1<...
02/02/2012
20120028901TFPI INHIBITORS AND METHODS OF USE
The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood ...
02/02/2012
20120028972BIOMARKER ASSAYS FOR DETECTING OR MEASURING INHIBITION OF TOR KINASE ACTIVITY
Provided herein are methods for detecting and/or measuring the inhibition of TOR kinase activity in a subject and uses associated therewith....
02/02/2012
20120021436Crystal structure of human alpha-N-acetylglucosaminidase
The present invention provides the three-dimensional structure of human α-N-acetylglucosaminidase (NAGLU) protein. This crystallographic information is useful in the identification and development of novel binding compounds of NAGLU, NAGLU mutants, for example, those a...
01/26/2012
20120003668HIGH RESOLUTION COMPLEX STRUCTURE AND ALLOSTERIC EFFECTS OF LOW MOLECULAR WEIGHT ACTIVATORS ON THE PROTEIN KINASE PDK1
The present invention provides a mutant form of a protein kinase its production and its use for identifying compounds that bind to the PIF-binding pocket allosteric site of the protein kinase....
01/05/2012
20110311508METHOD OF MODULATING HSF-1
The present invention is directed to methods of modulating HSF1 activity comprising modifying the acetylation of the DNA binding domain of the HSF1....
12/22/2011
20110301160Inhibitors of P38 and Methods of Using the Same
In general, the present invention relates to compounds capable of inhibiting p38 in vivo or in vitro, and methods for treating conditions associated with p38 activity or cytokine activity....
12/08/2011
20110300076METHODS FOR PREPARATION OF ZnTe NANOCRYSTALS
Nanocrystals having a ZnTe core and methods for making and using them to construct core-shell nanocrystals are described. These core-shell nanocrystals are highly stable and provide quantum yields and stability suitable for applications such as flow cytometry, cellular ...
12/08/2011
20110293746Modulation of Gsk-3Beta and Method of Treating Proliferative Disorders
There is provided methods and uses for promoting cell death, when combined with chemotherapeutic agents, in an abnormally proliferating cell, and for treating a proliferative disorder in a subject, which methods and uses involve contacting a cell with, or administering ...
12/01/2011
20110280808Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-Like Proteins
The present invention relates to novel compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and of diseases or conditions associated with amyloid-like proteins. The compou...
11/17/2011
20110275524METHODS AND SYSTEMS TO DETECT AN ACTIVE PROTEASE IN A SAMPLE
Provided herein are a method and system to detect an active protease in a sample, and related methods and systems to diagnose a condition in an individual, the condition being associated to abnormal protease activity in the individual....
11/10/2011
20110274692Screening Methods
The present invention provides polypeptide binding agents, e.g. antibodies, that exhibit the ability to kinetically modulate the binding and signaling of biological signaling complexes, e.g., receptor-ligand complexes; methods of identifying such polypeptide binding age...
11/10/2011
20110269674SYNTHETIC OR NATURAL PEPTIDES BINDING PROTEIN PHOSPHATASE 2A, IDENTIFICATION METHOD AND USES
The present invention relates to novel synthetic or natural peptides for use in treating viral or parasitic infections or in the treatment of tumors. The peptides of the present invention are less than 30 amino acids in size, preferably less than 20 amino acids, in part...
11/03/2011
20110262355COMPOSITIONS COMPRISING ENZYME-CLEAVABLE OPIOID PRODRUGS AND INHIBITORS THEREOF
Pharmaceutical compositions and their methods of use are provided, where the pharmaceutical compositions comprise an opioid prodrug that provides enzymatically-controlled release of an opioid, and an enzyme inhibitor that interacts with the enzyme(s) that mediates the e...
10/27/2011
20110262936METHOD OF DETERMINING A CONCENTRATION OF ANALYTES OF INTEREST IN A SAMPLE
A method of determining a concentration of analytes of interest in a sample reaction mixture is disclosed. The method can include measuring intensities of the polarized fluorescence of at least one comparative reaction mixture containing different, known amounts of the ...
10/27/2011
20110262360Compositions Comprising Enzyme-Cleavable Phenol-Modified Opioid Prodrugs and Inhibitors Thereof
Pharmaceutical compositions and their methods of use are provided, where the pharmaceutical compositions comprise a phenol-modified opioid prodrug that provides enzymatically-controlled release of a phenolic opioid, and an enzyme inhibitor that interacts with the enzyme...
10/27/2011
20110262359COMPOSITIONS COMPRISING ENZYME-CLEAVABLE PRODRUGS OF ACTIVE AGENTS AND INHIBITORS THEREOF
The present disclosure provides pharmaceutical compositions, and their methods of use, where the pharmaceutical compositions comprise a prodrug that provides enzymatically-controlled release of a drug and an enzyme inhibitor that interacts with the enzyme(s) that mediat...
10/27/2011
20110257028Method for selectively binding a substrate to sorbents by way of at least bivalent bonds
A method for the manufacture of at least one sorbent having at least two different groups, which are capable of binding, for the selective binding of a substrate, characterized in that it comprises the steps (i) to (ii):
  • 10/20/2011
20110256064Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins
The present invention relates to novel compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and of diseases or conditions associated with amyloid-like proteins. The compou...
10/20/2011
20110256553Methods
A method for assessing the effect of a test compound on LRRK2 in a cell-based system, the method comprising the steps of a) assessing the effect of exposing the cell-based system comprising LRRK2 to the test compound on the phosphorylation state of Ser910 and/or Ser935 ...
10/20/2011
20110251090PANCREATIC CANCER RELATED GENE TTLL4
The present invention relates to the roles played by TTLL4 genes in pancreatic cancer carcinogenesis and features a method for treating or preventing pancreatic cancer by administering a double-stranded molecule against one or more of the TTLL4 genes or a composition, v...
10/13/2011
20110244480 METHOD OF DIAGNOSIS AND KIT THEREFOR
The invention provides kits and methods for detecting or monitoring the number of cells in sample. The cell comprises a cell surface associated protein (CSAP) comprising a cytoplasmic (cytosolic) and an extracellular (ecto) domain. The kit comprises: (i) a chromatograph...
10/06/2011
20110244481COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES
Coelenterazine analogues with different luminescence properties from conventional ones and coelenteramide analogues with different fluorescence properties from conventional ones have been desired. The invention provides coelenterazine analogues modified at the 8-positio...
10/06/2011
20110243910 MAMMALIAN RNA DEPENDENT RNA POLYMERASE
The invention provides compositions comprising a TERT-RMRP or TERT-RNA complex and methods of treating subjects with genetic diseases in which gene silencing is either increased by administering the compositions of the invention or decreased by administering an inhibito...
10/06/2011
20110244487METHODS FOR TESTING BINDING OF A LIGAND TO A G PROTEIN-COUPLED RECEPTOR
The present invention relates to methods for testing for the binding of a ligand to a G Protein-Coupled Receptor. In particular, the methods of the invention are useful in high throughput screening for ligands which bind to G Protein-Coupled Receptors....
10/06/2011
20110217401Aging-Related Circulating Particle-Associated Lipoprotein B Oxidase (apoBNOX) and Inhibitors Thereof
Provided is an age-related apolipoprotein B oxidase (apoBNOX) found tightly associated with the low-density lipoprotein particles and believed to be responsible for oxidizing lipoprotein particles and initiating atherogenesis. It causes damage by directly oxidizing the ...
09/08/2011
20110212467INHIBITORS OF dUTPase
Evidence demonstrating that elevated expression of dUTPase protects breast cancer cells from the expansion of the intracellular uracil pool, translating to reduced growth inhibition following treatment with 5-FU is provided. The implementation of in silica drug developm...
09/01/2011
20110212466Thiol-Modified Surface Immobilization Article And Method
A method and article to immobilize a protein, including, for example, combining the protein and a mixture comprised of an activated spacer compound having a maleimide group in a buffer solution, to form a maleimide-modified protein; and contacting the maleimide-linker-m...
09/01/2011
20110207656MUC1, CASPASE-8, and DED-CONTAINING PROTEINS
The disclosure features a variety of compositions and methods for modulating an interaction between MUC1 and caspase-8 and/or an interaction between MUC1 and a DED-containing protein (e.g., an anti-apoptotic DED-containing protein or a pro-apoptotic DED-containing prote...
08/25/2011
20110201027BIOSENSOR FOR DETECTING A TRACE AMOUNT OF SAMPLE AND PRODUCTION METHOD THEREFOR
The present invention relates to a biosensor capable of a trace amount of sample and a fabrication method thereof. More specifically, the invention relates to a method for fabricating a biosensor, the method comprising: immobilizing a receptor molecule, which binds sele...
08/18/2011
20110201025Polymer-coupled peptidases
The present invention is directed to a simple process for the modification of the specificity of a peptidase of the hemostatic system by coupling polymers to the peptidase causing it to lose its reactivity in the hemostatic system, but enabling it to continue to react w...
08/18/2011
20110195425SYSTEMS AND METHODS FOR DIAGNOSING PARASITE INFECTIONS
Systems and methods for diagnosing parasite infections. According to at least one embodiment of a stabilizing system of the present disclosure, a stabilizing system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation o...
08/11/2011
20110195423SYSTEMS AND METHODS FOR DIAGNOSING BACTERIAL INFECTIONS
Systems and methods for diagnosing bacterial infections. According to at least one embodiment of a system of the present disclosure, the system a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a bac...
08/11/2011
20110195396CHEWABLE COMPOSITIONS FOR THE STABILIZATION OF DIAGNOSTIC BIOMARKERS
Chewable compositions for the stabilization of diagnostic biomarkers. In at least one embodiment of a chewing gum composition useful to stabilize a diagnostic marker, the a chewing gum composition comprises a stabilizing agent useful to completely or substantially preve...
08/11/2011
20110195401SYSTEMS AND METHODS FOR DETERMINING FOOD ALLERGIES
Systems and methods for determining food allergies. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a food all...
08/11/2011
20110195400SYSTEMS AND METHODS FOR DIAGNOSING CANCER
Systems and methods for diagnosing cancer. According to at least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker f...
08/11/2011
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