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| Application No. | Application Title | Issue Date |
| 20120070851 | ANTIBODY SPECIFIC TO METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS, DETECTION METHOD AND KIT FOR METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS USING THE SAME The present invention relates to an antibody against a protein specifically expressed in methicillin-resistant strains of Staphylococcus aureus (MRSA), and a method and a kit for detecting MRSA. The present invention enables a fast and accurate detection of MRSA ... | 03/22/2012 |
| 20120034617 | ASSAYS FOR BACTERIAL DETECTION AND IDENTIFICATION The invention herein generally relates to kits and methods for detecting the presence of a bacterium in a subject, for example, methicillin resistant S. aureus. In certain embodiments, the invention provides a method of detecting presence of a bacterium in a samp... | 02/09/2012 |
| 20120003661 | METHODS AND DEVICES FOR THE SELECTIVE DETECTION OF MICROORGANISMS Methods and devices are provided for the rapid and specific detection of target microorganisms, cells, and the like. In one embodiment, the methods involve contacting a target microorganism (e.g., in a sample) with a permeabilization reagent that selectively permeabiliz... | 01/05/2012 |
| 20110294109 | METHODS FOR DETECTING AN ANALYTE Methods of decreasing non-specific binding in solid phase assays for an analyte are disclosed. In the methods, the solid phase apparatus (lateral flow solid phase apparatus or capillary flow solid phase apparatus) is subjected to elevated heat. The elevated heat can be ... | 12/01/2011 |
| 20110268739 | Human binding molecules having killing activity against enterococci and uses thereof Described are human binding molecules specifically binding to enterococci and having killing activity against enterococci, nucleic acid molecules encoding the human binding molecules, compositions comprising the human binding molecules and methods of identifying or prod... | 11/03/2011 |
| 20110201032 | Immunosensors: scFv-linker design for surface immobilization An apparatus and methods for binding an analyte of interest in a sample are provided. The apparatus comprises a substrate with an exposed surface with an compound, that is electrostatically charged or capable of forming hydrogen bonds, provided bound to the solid substr... | 08/18/2011 |
| 20110183316 | METHODS FOR DETECTING ORGANISMS AND ENZYMATIC REACTIONS USING RAMAN SPECTROSCOPY The present disclosure provides systems for the rapid and sensitive detection of organisms and molecules in samples. Reactants that produce Raman-active products are used in combination with Raman light scattering. The present disclosure can also be used to measure enzy... | 07/28/2011 |
| 20110020323 | GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.... | 01/27/2011 |
| 20110020240 | Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics Provided herein are imaging methods for detecting, diagnosing and imaging pathogenic bacteria or a pathophysiological condition associated therewith using fluorogenic substrates for bacterial enzymes. Fluorescent, luminescent or colorimetric signals emitted by substrate... | 01/27/2011 |
| 20100227810 | METHOD FOR DIAGNOSING STAPHYLOCOCCAL INFECTIONS The present invention relates to a method for determining if an individual is infected by a staphylococcus bacterium, comprising:
| 09/09/2010 |
| 20100216711 | Protease-Stable, Cell Wall-Lysing Enzymes The present invention relates to a modified polypeptide with a biological activity to lyse cell walls of bacteria, wherein the polypeptide has no caspase, clostripain, enterokinase, factor Xa, granzyme B, staphylococcus peptidase I (V8 Protease), plasmin, strepto... | 08/26/2010 |
| 20100209946 | USES OF WATER-DISPERSIBLE SILICA NANOPARTICLES FOR ATTACHING BIOMOLECULES Uses of silica nanoparticles functionalized with water-dispersible groups, shielding groups, and biomolecule-binding groups.... | 08/19/2010 |
| 20100183623 | MONOCLONAL ANTIBODIES RECOGNIZING A COAGULASE-NEGATIVE STAPHYLOCOCCAL PROTEIN Monoclonal antibodies which can bind to the SdrF protein of Staphylococcus epidermidis are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus epidermidis. The monoclonal antibo... | 07/22/2010 |
| 20100120073 | METHODS AND DEVICES FOR DETECTING ORGANISMS CAUSING URINARY TRACT INFECTIONS The invention provides for devices and methods for detecting an organism causing a urinary tract infection. In a preferred embodiment, detecting the organism causing a urinary tract infection follows a preliminary indication of a urinary tract infection by a urinary mon... | 05/13/2010 |
| 20100119477 | PSM PEPTIDES AS VACCINE TARGETS AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS This disclosure concerns compositions and methods for the treatment and inhibition of infectious disease, particularly methicillin-resistant Staphylococcus. In certain embodiments, the disclosure concerns immunogenic peptides, for instance PSM peptides, which can... | 05/13/2010 |
| 20100099088 | RELIABLE DETECTION OF VANCOMYCIN-INTERMEDIATE STAPHYLOCOCCUS AUREUS The present invention relates to a method for identifying a VISA strain in a sample comprising measuring SAV2095 expression levels, a kit and use of SAV2095 for same. The present invention also relates to a method for facilitating the development of an individualized tr... | 04/22/2010 |
| 20100092487 | TOXIC DETECTION METHOD According to the present invention, an antibody against a Panton-Valentine leukocidin toxin contained in Staphylococcus aureus, a method and a kit for detecting the toxin with the use of the antibody, and a pharmaceutical composition containing an antibody agains... | 04/15/2010 |
| 20100081616 | EXTRACELLULAR MATRIX-BINDING PROTEINS FROM STAPHYLOCOCCUS AUREUS An isolated extracellular matrix-binding protein, designated as SdrD and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions thereof are useful for the prevention, inhibition, ... | 04/01/2010 |
| 20100075347 | METHODS OF DETECTION USING ACOUSTO-MECHANICAL DETECTION SYSTEMS Methods for detecting target biological analytes within sample material using acousto-mechanical energy generated by a sensor are disclosed. The acousto-mechanical energy may be provided using an acousto-mechanical sensor, e.g., a surface acoustic wave sensor such as, e... | 03/25/2010 |
| 20100055721 | Surface Enhanced Raman Scattering and Multiplexed Diagnostic Assays Multiplexed lateral flow assays, related methods, and devices are disclosed which are capable of simultaneously detecting multiple analytes. The assays are preferably immunoassays and can be multiplexed spatially, spectrally, and both spatially and spectrally. Multiplex... | 03/04/2010 |
| 20100035234 | VACCINE ASSAYS The present invention is directed to methods, assays and compositions for implementing such methods and assays for assessing efficacy of individual components in multi-component vaccines and for assessing efficacy of a vaccine against a pathogen. In one aspect, the meth... | 02/11/2010 |
| 20100008943 | EXTRACELLULAR MATRIX-BINDING PROTEINS FROM STAPHYLOCOCCUS AUREUS An isolated extracellular matrix-binding protein, designated as SdrC and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions thereof are useful for the prevention, inhibition, ... | 01/14/2010 |
| 20090239216 | Novel Tannase Gene And Protein Thereof A polynucleotide encoding a protein as defined in the following (a), (b) or (c):
| 09/24/2009 |
| 20090202578 | SURFACE PROTEINS FROM COAGULASE-NEGATIVE STAPHYLOCOCCI AND STAPHYLOCOCCUS AUREUS THAT GENERATE CROSS-REACTIVE MONOCLONAL AND POLYCLONAL ANTIBODIES Surface proteins are provided which generate polyclonal and monoclonal antibodies which are cross-reactive to both coagulase-positive staphylococcus bacteria, such as S. aureus and to coagulase-negative bacteria, such as S. epidermidis and S. hem... | 08/13/2009 |
| 20090169562 | Human Binding Molecules Having Killing Activity Against Enterococci and Uses Thereof The present invention provides human binding molecules specifically binding to enterococci and having killing activity against enterococci, nucleic acid molecules encoding the human binding molecules, compositions comprising the human binding molecules and methods of id... | 07/02/2009 |
| 20090162379 | Inhibitors of S. aureus SdrD protein attachment to cells and uses therefor Provided herein is a method for identifying small molecule inhibitors of S. aureus SdrD protein attachment to a host cell receptor using a structural model of SdrD protein-receptor interaction. Also provided are the small molecule inhibitors so identified and syn... | 06/25/2009 |
| 20090130115 | ANTIBODIES RECOGNIZING A HIGHLY EXPRESSED PUTATIVE ANTIGEN OF CA-MRSA AND METHODS OF USE The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus be utilized in methods of generati... | 05/21/2009 |
| 20080299127 | PROTECTIVE STAPHYLOCOCCUS AUREUS VACCINE BASED ON CELL WALL-ASSOCIATED PROTEINS The present invention relates to a pharmaceutical composition or a medicament, notably a protective Staphylococcus aureus vaccine, comprising at least one cell wall-associated Staphylococcus aureus protein or a fragment or derivative thereof causing an imm... | 12/04/2008 |
| 20080171346 | Immunosensors: scFv-linker design for surface immobilization An apparatus and methods for binding an analyte of interest in a sample are provided. The apparatus comprises a substrate with an exposed surface with an compound, that is electrostatically charged or capable of forming hydrogen bonds, provided bound to the solid substr... | 07/17/2008 |
| 20080118937 | ANTIBODY WITH PROTEIN A SELECTIVITY Monoclonal antibodies, and antigen binding fragments thereof, which bind to Protein A of Staphylococcus aureus are provided.... | 05/22/2008 |
| 20080038287 | Method For Identification, Isolation and Production of Antigens to a Specific Pathogen Described is a method for identification, isolation and production of hyperimmune serum-reactive antigens from a specific pathogen, a tumor, an allergen or a tissue or host prone to autoimmunity, said antigens being suited for use in a vaccine for a given type of animal... | 02/14/2008 |
| 20080020382 | Biological Microbeads for Various Flow Cytometric Applications The invention relates to biological microbeads, and in certain embodiments, to the use thereof in flow-cytometric applications. Biological microbeads are fixed cells that may be surface-modified with proteins or other molecules that have specific binding properties. The... | 01/24/2008 |
