Bizarre Patents
Crispy Chip Sandwich and Process of Producing a Sandwich Product
A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.
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| Application No. | Application Title | Issue Date |
| 20120129192 | Apparatus and Methods for Detection of Tumor Cells in Blood In one embodiment, the present invention provides the description of an inexpensive and disposable handheld device for detecting Circulating tumor cells (CTC) in blood called a handheld CTC detector (HCTCD). The HCTCD is capable of detecting less than 1 CTC per m... | 05/24/2012 |
| 20120128665 | PRESELECTION OF SUBJECTS FOR THERAPEUTIC TREATMENT BASED ON HYPOXIC STATUS The present invention provides methods for the preselection of a subject for therapeutic treatment with an agent based on modulated levels of hypoxia in cancerous cells in the subject. In one embodiment, the invention provides methods for the preselection of a subject f... | 05/24/2012 |
| 20120129712 | ANTIBODIES DIRECTED TO TRA ANTIGENS, AND METHODS OF PRODUCTION, SCREENING AND ANALYSIS OF SAID ANTIBODIES, AS WELL AS METHODS OF ANALYSIS OF STEM CELLS AND CANCER CELL A complex of Tra-antibody bound to an isolated glycan comprising type I—N-acetyllactosamine comprising target structure, and methods and uses utilizing said complex.... | 05/24/2012 |
| 20120129190 | ENSEMBLE-DECISION ALIQUOT RANKING Provided herein, among other aspects, are methods and apparatuses for ranking aliquots from a suspension containing bioparticles. In certain embodiments, the bioparticles may be cells, organelles, proteins, DNAs, debris of biological origin, microbeads coated with biolo... | 05/24/2012 |
| 20120128681 | Anti-CK8 Antibodies To Be Used For Treating Colorectal Cancers And Identifying Metastatic And/Or Invasive Phenotypes The invention relates to antibodies specific to human CK8 and to pharmaceutical compositions for preventing and treating colorectal cancers. The invention also relates to methods for identifying colorectal cancers with an invasive and/or metastatic phenotype including d... | 05/24/2012 |
| 20120129711 | BIOMARKERS FOR THE PROGNOSIS AND HIGH-GRADE GLIOMA CLINICAL OUTCOME The present invention relates to the identification and use of biomarkers with clinical relevance to high grade gliomas (HGGs). In particular, the invention provides the identity of four genes, CHAF1B, PDLIM4, EDNRB and HJURP, whose expression, at the transcriptome and ... | 05/24/2012 |
| 20120129191 | COCKTAIL ANTIBODY, DETERMINATION KIT AND DETERMINATION METHOD FOR DETERMINING HISTOLOGICAL TYPE OF CARCINOMA The present invention provides a cocktail antibody useful for determining the histological type of cancer, and a determination method using the same cocktail antibody is disclosed. A determination kit is also provided. The cocktail antibody... | 05/24/2012 |
| 20120108455 | Methods for assessing and identifying or evolving conditionally active therapeutic proteins Methods for evolving or selecting or producing therapeutic proteins that exhibit reduced adverse side-effects and the resulting proteins are provided. For example, provided herein is an in vitro assay to identify conditionally active therapeutic proteins that exhibit be... | 05/03/2012 |
| 20120107837 | METHOD FOR SCREENING ANTICANCER SUBSTANCES, SET OR KIT FOR IMPLEMENTING SAID METHOD A method for screening anticancer substances including the following steps:
| 05/03/2012 |
| 20120107838 | Cancer Diagnostics The invention concerns kits and methods for the diagnosis, prognosis and monitoring of cancer. In one aspect, there is provided a method for identifying whether or not a mammal is suffering from cancer, wherein the method comprises the steps of: (a) measuring a signal d... | 05/03/2012 |
| 20120107839 | NMR DEVICE FOR DETECTION OF ANALYTES This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a tar... | 05/03/2012 |
| 20120107321 | Antibodies And Epitopes Specific To Misfolded Prion Protein The present invention relates to antibodies and immunogenic peptides specific to misfolded prion protein (PrP, e g, PrPSc), and uses thereof. The immunogenic peptides comprise the amino acid sequence tyrosine-methionine-leucine (YML). The antibodies or peptid... | 05/03/2012 |
| 20120082655 | Downregulation of SPY1 by p53 as an essential component of p53-mediated effects The present invention relates to a novel method of treating or preventing cancer as well as a novel method for diagnosing or monitoring cancer, wherein the cancer is caused by delayed entry to cellular senescence. More particularly, the present invention relates to a no... | 04/05/2012 |
| 20120083005 | METHODS FOR IN VITRO CANCER CELL DETECTION, DIAGNOSIS AND THERAPY USING MULTIDOMAIN BIOTAGS In one embodiment, a biotag for targeting a cancer biomarker is provided. The biotag may include a cancer biomarker binding domain, an internalization domain, an endosomal escape domain, a lysosomal escape domain, a reporter binding domain, and a reporter, wherein the r... | 04/05/2012 |
| 20120083006 | METHODS FOR THE IDENTIFICATION OF KINASE INTERACTING MOLECULES AND FOR THE PURIFICATION OF KINASE PROTEINS The present invention relates to immobilization compounds (I), immobilization products and preparations thereof as well as methods and uses for the identification of kinase interacting compounds or for the purification or identification of kinase proteins. 04/05/2012 | |
| 20120070450 | LEUKEMIA STEM CELL MARKERS The invention provides a test method for predicting the initial onset or a recurrence of acute myeloid leukemia (AML) comprising (1) measuring the expression level of human leukemic stem cell (LSC) marker genes in a biological sample collected from a subject for a trans... | 03/22/2012 |
| 20120070849 | METHODS AND COMPOSITIONS FOR RISK STRATIFICATION The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, and the... | 03/22/2012 |
| 20120070819 | Determination of Interactions of Constant Parts of Antibodies with FC-Gamma Receptors The invention relates to a novel method for the exact determination of the binding of the Fc-part of IgG-antibodies to Fc-gamma receptors, and for the simultaneous examination of the antigen-specificity and the Fc-gamma-receptor activation, as well as specific materials... | 03/22/2012 |
| 20120071417 | METHODS OF INHIBITING CANCER CELL GROWTH WITH HDAC INHIBITORS AND METHODS OF SCREENING FOR HDAC10 INHIBITORS Methods of inhibiting cancer cell growth using HDAC10 inhibitors are provided. Methods of treating cancer in a subject using HDAC10 inhibitors are also provided. In certain embodiments, at least one second inhibitor selected from an autophagy inhibitor, an AMPK inhibito... | 03/22/2012 |
| 20120071418 | Inhibitors of Human EZH2 and Methods of Use Thereof The invention relates to inhibition of wild-type and certain mutant forms of human histone methyltransferase EZH2, the catalytic subunit of the PRC2 complex which catalyzes the mono- through tri-methylation of lysine 27 on histone H3 (H3-K27). In one embodiment the inhi... | 03/22/2012 |
| 20120070848 | TUMOR CELL-DERIVED MICROVESICLES The present invention relates to a method for diagnosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a sample of a subject by detecting oncogenic proteins in microvesicles, and to the use of an age... | 03/22/2012 |
| 20120071347 | COMPOSITIONS AND METHODS FOR MONITORING AND DETECTING CANCEROUS CONDITIONS A method for monitoring or detecting a prostate condition in a subject comprises determining Engrailed-2 (EN2) gene, Paired Box 2 (PAX2) gene, and/or β defensin-1 (DEFB1) gene expression levels in a biological sample from the subject. The expression levels of EN2, PAX2... | 03/22/2012 |
| 20120052009 | Imaging probes, methods of making imaging probes, and methods of imaging In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of detecting the over-expression of epidermal growth factor receptor (EGFR) in a subject or sam... | 03/01/2012 |
| 20120052071 | TUMOR MARKERS AND METHODS OF USE THEREOF The invention provides newly identified proteins as markers for the detection of tumors, or as targets for their treatment, particularly of tumors affecting lung, colon, breast, ovary; affinity ligands capable of selectively interacting with the newly identified markers... | 03/01/2012 |
| 20120052513 | GOLD SUB-NANOCLUSTERS AND USES THEREOF The present technology relates gold sub-nanoclusters comprising a gold core and one or more thiolates bound to the gold core, wherein the gold core consists essentially of 23 gold atoms. Methods of preparing and using such sub-nanoclusters are also provided.... | 03/01/2012 |
| 20120052076 | ANTI-TROP-2 MONOCLONAL ANTIBODIES AND USES THEREOF IN THE TREATMENT AND DIAGNOSIS OF TUMORS The present invention teaches anti-Trop-2 monoclonal antibodies with high affinity and able to recognize different regions of the Trop-2 molecule, and uses thereof in the treatment and diagnosis of tumors, such as for example endometrium, breast, head and neck, colon-re... | 03/01/2012 |
| 20120045766 | JARID1B FOR TARGET GENE OF CANCER THERAPY AND DIAGNOSIS The present invention relates to the roles played by the JARID1B genes in cancers and features a method for treating cancers by administering a composition comprising a double-stranded molecule against the JARID1B genes or a vector encoding them. The present invention a... | 02/23/2012 |
| 20120046195 | DETECTING BCL-B EXPRESSION IN CANCER AND USES THEREOF Provided herein are compositions and methods of detecting Bcl-B expression in cancer cells to prognose, monitor, or select therapies for cancers such as breast cancer, prostate cancer, lung cancer, or gastric cancer.... | 02/23/2012 |
| 20120045501 | CONNEXIN ENHANCES CHEMOTHERAPY-INCLUDED APOPTOSIS IN HUMAN CANCER CELLS INHIBITING TUMOR CELL PROLIFERATION The present invention provides methods and compositions for the inhibition of proliferation rate of target cells, for example tumor cells. In particular, a nucleic acid encoding a connexin protein, fragment, derivative or analog thereof can be incorporated into a target... | 02/23/2012 |
| 20120040366 | COMPOSITIONS, METHODS AND USES FOR DISEASE DIAGNOSIS Embodiments of the present invention generally related to methods and compositions for diagnosing or predicting a genetic disorder. In certain embodiments, the methods may include use of rapid and inexpensive assay systems. Other embodiments concern novel mutation speci... | 02/16/2012 |
| 20120040375 | ANTI-MUC1 ANTIBODY An object of the present invention is to provide an antibody which does not bind to a normal cell, and is specific for a cancer cell. The object was solved by the finding by the present inventors that an antibody obtained by immunizing an animal using a 2,3ST glycopepti... | 02/16/2012 |
| 20120041017 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF Pyridocarbazole-type compounds of formula (I): are provided as a medicament, and more particularly for application in anticancer chemotherapy. Also provided is a pharmaceutical composition with the compound a... | 02/16/2012 |
| 20120039805 | Therapeutics And Methods For Treating Neoplastic Diseases Comprising Determining The Level Of Caveolin-1 And/Or Caveolin-2 In A Stromal Cell Sample The invention provides diagnostic and therapeutic methods for neoplastic disease patients with neoplasms of for example, the breast, skin, kidney, lung, pancreas, rectum and colon, prostate, bladder, epithelial, non-epithelial; lymphomas, sarcomas, melanomas, and the li... | 02/16/2012 |
| 20120039915 | GLIOBLASTOMA MULTIFORME-REACTIVE ANTIBODIES AND METHODS OF USE THEREOF The present disclosure is generally related to antibodies that bind specifically to glioblastoma multiforme (GBM) cells. In particular, the present disclosure provides compositions comprising human single chain or full-length antibodies that bind tumor cells. Additional... | 02/16/2012 |
| 20120034317 | Prediction of Response to Platinum-Based Therapy Method for determining whether a mammalian subject having a cancer belongs to a first or a second group, wherein subjects of the first group are more likely to respond to a platinum-based therapy than subjects of the second group, comprising the steps of: evaluating the... | 02/09/2012 |
| 20120034167 | TYROSINE KINASE RECEPTOR TYRO3 AS A THERAPEUTIC TARGET IN THE TREATMENT OF CANCER The present invention concerns new methods for treating cancer by using TYRO3 inhibitors and methods for identifying new molecules of interest for treating cancer.... | 02/09/2012 |
| 20120034168 | Isolated Monoclonal Antibody or Fragment Thereof Binding Prostate Specific Membrane Antigen, Conjugates and Uses Thereof An isolated monoclonal antibody or fragment thereof binding prostate specific membrane antigen (PSMA) preferably in its native form on the surface of tumour cells. A conjugate of the antibody with an active ingredient and modified forms of the antigen-binding antibody f... | 02/09/2012 |
| 20120034210 | COMPOSITIONS FOR POTENTIATING APOPOSIS SIGNALS IN TUMOUR CELLS The present invention concerns a composition for potentiating formation of DISC (Death Inducing Signaling Complex) macro-complex and for inducing apoptotic signal mediated by death receptors in tumour cells comprising a therapeutically effective amount of an active agen... | 02/09/2012 |
| 20120034628 | STANDARDIZED EVALUATION OF THERAPEUTIC EFFICACY BASED ON CELLULAR BIOMARKERS The present invention provides materials and methods for predicting the response of a disease state to a therapeutic agent. A targeting moiety specific for a biological marker is labeled with a reporter moiety and used to analyze cells characteristic of the disease stat... | 02/09/2012 |
| 20120034218 | RBM3 in Colorectal Cancer Prognostics The present invention provides means, such as a method, for determining whether a mammalian subject having a colorectal cancer belongs to a first or a second group, wherein the prognosis of subjects of the first group is better than the prognosis of subjects of the seco... | 02/09/2012 |
