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| Application No. | Application Title | Issue Date |
| 20110195425 | SYSTEMS AND METHODS FOR DIAGNOSING PARASITE INFECTIONS Systems and methods for diagnosing parasite infections. According to at least one embodiment of a stabilizing system of the present disclosure, a stabilizing system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation o... | 08/11/2011 |
| 20110117107 | COMPOSITIONS AND METHODS FOR DIAGNOSIS, PROGNOSIS AND MANAGEMENT OF MALARIA Biomarkers for predicting the severity of malaria and methods for their detection are disclosed. In one aspect, the present application discloses CXCL4, CXCL10, VEGF, PGDF, IL-1Ra, IL-8, MIP-1β, sFas, Fas-L, sTNF-R2, and sTNF-R1 as biomarkers for the severity of malari... | 05/19/2011 |
| 20110098326 | 2-FLUOROTHIAZOLE DERIVATIVES USEFUL AS IMAGING AGENTS; METHODS OF SYNTHESIS, AND METHODS OF USE Novel 18F-labeled thiazole derivatives useful for imaging of metabotropic glutamate subtype 5 receptors (mGluR5) in living mammalian brain are disclosed herein. Also disclosed herein is a synthetic method for making the claimed thiazole derivatives under ther... | 04/28/2011 |
| 20110081666 | ANTI-PSGL-1 INHIBITORS AND SCREENING METHODS The present invention is directed to antibodies and binding fragments thereof, which bind with high affinity and specificity to human P-selectin glycoprotein ligand 1 (PSGL-1) and which block both selectin and chemokine binding to PSGL-1 expressed on leukocytes, lymphoc... | 04/07/2011 |
| 20110039256 | DETECTION METHOD A method for detecting the presence of a diagnostic moiety indicative of exposure to an infectious organism in a biological sample taken from a human or animal, said method comprising; (a) adding to said sample a first fluorescently labelled reagent which binds said dia... | 02/17/2011 |
| 20100279319 | Detection of plasmodium falciparum histidine-rich protein II in saliva malaria patients The detection of PfHRP II in saliva offers a practical, cost-effective alternative to PfHRP II detection in blood as a means for diagnosis of malaria. Collection of saliva is non-invasive, simple, safe, stress free, painless and can be accomplished in primitive settings... | 11/04/2010 |
| 20100233731 | DETECTION AND MEASUREMENT OF BLOOD-FEEDING ACTIVITY This invention provides compositions and methods for detection of hematophagous ectoparasitic activity in an enclosure or area. The compositions comprise a reagent or reagents which are reactive against antigens or markers as they appear in the excrement or other ectopa... | 09/16/2010 |
| 20100151500 | Compositions, Devices, Kits and Methods for Detecting Hookworm Methods, devices, kits and compositions for detecting the presence or absence of hookworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of hookworm in a fecal s... | 06/17/2010 |
| 20100120017 | RAPID IMMUNE CHROMATOGRAPHIC DETECTION BY AMPLIFICATION OF THE COLLOIDAL GOLD SIGNAL The present invention relates to a rapid immunochromatographic test device suitable to detect more than one target in a single assay at the same time, uses of said device for detecting diseases in a sample, a method for the production of said device as well as a kit com... | 05/13/2010 |
| 20100120071 | DETECTION AND MEASUREMENT OF BLOOD-FEEDING ACTIVITY This invention provides compositions and methods for detection of hematophagous ectoparasitic activity in an enclosure or area. The compositions comprise a reagent or reagents which are reactive against antigens or markers as they appear in the excrement or other ectopa... | 05/13/2010 |
| 20100092520 | Recombinant Plasmodium Falciparum Merozoite Surface Proteins 4 and 5 and Their Use Accordingly, the invention provides constructs in which the nucleic acids encoding Plasmodium falciparum MSP4 and MSP5, and the resulting polypeptides, have been modified. More particularly, this invention provides constructs encoding recombinant MSP4 and MSP5 po... | 04/15/2010 |
| 20100068696 | UNIVERSAL BIOSENSOR AND METHODS OF USE The present invention relates to methods for detecting or quantifying an analyte in a test sample including providing at least one test mixture including a test sample, at least one marker complex, wherein each marker complex includes a particle, a marker, and one membe... | 03/18/2010 |
| 20100035234 | VACCINE ASSAYS The present invention is directed to methods, assays and compositions for implementing such methods and assays for assessing efficacy of individual components in multi-component vaccines and for assessing efficacy of a vaccine against a pathogen. In one aspect, the meth... | 02/11/2010 |
| 20090324582 | PROCESS FOR IDENTIFICATION OF MOLECULAR MIMICRY AND THE USES THEREOF The present invention discloses a process for simple and rapid detection and identification of molecular mimicry or mimic antigens or molecules existing in/on humans, animals and plants. The molecular mimicry can be related to infections, autoimmune diseases, cancers, o... | 12/31/2009 |
| 20090298195 | SYNTHETIC IMMUNOGLOBULIN DOMAINS WITH BINDING PROPERTIES ENGINEERED IN REGIONS OF THE MOLECULE DIFFERENT FROM THE COMPLEMENTARITY DETERMINING REGIONS Method for engineering an immunoglobulin comprising at least one modification in a structural loop region of said immunoglobulin and determining the binding of said immunoglobulin to an epitope of an antigen, wherein the unmodified immunoglobulin does not significantly ... | 12/03/2009 |
| 20090286227 | Methods, Devices, Kits and Compositions for Detecting Whipworm Methods, devices, kits and compositions for detecting the presence or absence of whipworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of whipworm in a fecal s... | 11/19/2009 |
| 20090286231 | Methods, Devices, Kits and Compositions for Detecting Roundworm, Whipworm, and Hookworm Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of... | 11/19/2009 |
| 20090286228 | Methods, Devices, Kits and Compositions for Detecting Roundworm Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a f... | 11/19/2009 |
| 20090286230 | Methods, Devices, Kits and Compositions for Detecting Roundworm Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal... | 11/19/2009 |
| 20090226941 | Detection of Trichomonas The present invention is directed to diagnostic devices and methods for detecting Trichomonas infections.... | 09/10/2009 |
| 20090215696 | Toxoplasma gondii Oocyst Protein Recombinant proteins have been developed for the detection of Toxoplasma gondii oocyst proteins for example in biological fluids. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA m... | 08/27/2009 |
| 20090215086 | Biomarkers for Babesia The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying babesia status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as infected with babesia or not infected... | 08/27/2009 |
| 20090215087 | Toxoplasma gondii Oocyst Protein Recombinant proteins have been developed for the detection of Toxoplasma gondii oocyst proteins for example in biological fluids. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA m... | 08/27/2009 |
| 20090208501 | Anti-Pathogen Immunoadhesins Chimeric molecules that include a pathogen recognition module derived from a pathogen binding domain of a pathogen recognition protein, e.g., a toll-like receptor (TLR), CD14, BPI, MD-2, scavenger receptors (SRs), surfactant proteins (SP), C-reactive protein (CRP), Mann... | 08/20/2009 |
| 20090209470 | T24 ANTIGEN FOR IMMUNODIAGNOSIS OF TAENIA SOLIUM CYSTICERCOSIS The present disclosure relates to T24 nucleic acid sequences, amino acid sequences, and antibodies. Methods for detecting and diagnosing Taenia solium infection in a subject using the T24 sequences and specific binding agents are also disclosed. The T24 sequences... | 08/20/2009 |
| 20090196884 | Malaria Vaccines The present invention relates to a synthetic antigenic sequence which represents a combination of epitope-containing sequences from the highly polymorphic block 2 repeat region of K1-type Plasmodium falciparum merozite surface antigen (MSP1) and fusion proteins c... | 08/06/2009 |
| 20090196883 | Plasmodium vivax hybrid circumsporozoite protein and vaccine Described in this application is a synthetic P. vivax circumsporozoite protein useful as a diagnostic reagent, for antibody production, and as a vaccine protective against infection with any strain of P. vivax. ... | 08/06/2009 |
| 20090169554 | Polypeptides of Leishmania Major and Polynucleotides Encoding Same and Vaccinal, Therapeutical and Diagnostic Applications Thereof The present invention relates to new proteins of Leishmania major and to therapeutical and diagnostic applications thereof. More particularly, the present invention relates to excreted/secreted polypeptides and polynucleotides encoding same, compositions comprisi... | 07/02/2009 |
| 20090081708 | Methods and Compositions for Detection of Ehrlichia chaffeensis (VLPT) The invention provides methods and compositions for the detection of Ehrlichia chaffeensis. ... | 03/26/2009 |
| 20080318798 | Antigen Detection The present invention relates to methods of detecting specific cell surface antigens present in a sample of cells being tested and in particular blood group antigens, which methods do not employ the addition of extrinsic labels to detect said cell surface antigens. Typi... | 12/25/2008 |
| 20080311557 | DEVICE, KIT AND METHOD FOR HOOKWORM ANTIGEN CAPTURE AND DETECTION A device, kit and method for detecting the presence or absence of hookworm antigens. The device, kit and method of the present invention may be used to confirm the presence or absence of hookworm in a fecal sample that may be infected with one or more of roundworm, whip... | 12/18/2008 |
| 20080248497 | Detection of Anaplasma platys The invention provides compositions and methods for the detection of Anaplasma platys polynucleotides and polypeptides.... | 10/09/2008 |
| 20080248498 | METHODS AND COMPOSITIONS TO DIAGNOSE TRICHOMONAS INFECTION The present invention provides methods and compositions for diagnosing Trichomonas infection by detecting an antibody that specifically binds a Trichomonas α-actinin protein in a sample from a subject.... | 10/09/2008 |
| 20080138358 | Ex vivo animal or challenge model as method to measure protective immunity directed against parasites and vaccines shown to be protective in the method The invention relates to an ex vivo animal or challenge model as a method to identify protective (recombinant) proteins and rapidly measure protective immunity in intestinal segments directed against parasites and vaccines directed against parasitic infections. The inve... | 06/12/2008 |
| 20080107660 | Binding Agents The invention relates to binding agents which can be induced to aggregate in response to a specific stimulus. In preferred embodiments the binding agents comprise at least a binding member for a binding partner and the binding partner. At least one of the binding member... | 05/08/2008 |
| 20080096232 | Methods for the detection and diagnosis of Trypanosoma cruzi infection The present invention relates to the diagnosis of Trypanosoma cruzi infection.... | 04/24/2008 |
| 20080031878 | Polypeptides for the Diagnosis and Therapy of Leishamaniasis The present invention provides compounds and methods for the detection of anti-leishmanial antibodies in individuals suspected of infection with the protozoan parasite of the genus Leishmania, where the infectious agent is an Indian strain and similar or c... | 02/07/2008 |
| 20080019995 | Diagnostic Assay For Trypanosoma Cruzi Infection A sensitive, multicomponent diagnostic test for infection with T. cruzi, the causative agent of Chagas disease, including methods of making and methods of use. Also provided is a method for screening T. cruzi polypeptides to identify antigenic polypeptides... | 01/24/2008 |
| 20070269795 | METHOD FOR DETECTING THE VIABILITY OF TRICHURIS SUIS EGGS A method for detecting the viability of Trichuris suis eggs by simulating in vitro a passage of the eggs through the gastrointestinal passage of a swine with regard to chronological sequence and medium. The method involves subjecting the eggs in vitro first to ga... | 11/22/2007 |
| 20070237794 | Compounds and Methods for Diagnosis and Treatment of Leishmaniasis Compounds and methods are provided for diagnosing, preventing, treating and detecting leishmaniasis infection and stimulating immune responses in patients are disclosed. The compounds disclosed are include polypeptides and fusion proteins that contain at least one immun... | 10/11/2007 |
