Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Application No. | Application Title | Issue Date |
| 20120130350 | DETECTION AND TREATMENT OF AUTOIMMUNE DISORDERS Disclosed herein are methods of treatment of autoimmune diseases such as systemic lupus erythematosus (SLE) as well as clinical assays for detection of autoimmune disease activity in patients utilizing a PD1 ligand.... | 05/24/2012 |
| 20120128592 | SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) COMPOUNDS AND METHODS OF THEIR PREPARATION A compound for detecting an analyte using Surface Enhanced Raman Spectroscopy (SERS) and a method of forming the compound is provided. The compound has Formula I: wherein W is selected from the group consisti... | 05/24/2012 |
| 20120129189 | Methods of Controlling Cell Proliferation The present disclosure provides methods for increasing self-renewal/expansion of stem cells. The present disclosure provides methods of reducing uncontrolled cell proliferation. The present disclosure provides methods of identifying agents that modulate Notch1/-catenin ... | 05/24/2012 |
| 20120129193 | DEVICE AND METHOD FOR ANALYSING CELLS There is provided a carrier substrate for nonspecific immobilization of living bacterial and/or eukaryotic cells, especially of animal cells, which can be present as single cells, cell agglomerates or tissue sections. The surface of the carrier substrate is provided at ... | 05/24/2012 |
| 20120129721 | URINARY GM2 ACTIVATOR PROTEIN AS A MARKER OF ACUTE RENAL FAILURE OR THE RISK OF DEVELOPING ACUTE RENAL FAILURE The invention relates to a method of determining the risk of developing acute renal failure (ARF) in an individual, or of determining an ARF, and a method of predicting the progression of an ARF, by detecting and/or quantifying the protein Ganglioside GM2 Activator Prot... | 05/24/2012 |
| 20120129712 | ANTIBODIES DIRECTED TO TRA ANTIGENS, AND METHODS OF PRODUCTION, SCREENING AND ANALYSIS OF SAID ANTIBODIES, AS WELL AS METHODS OF ANALYSIS OF STEM CELLS AND CANCER CELL A complex of Tra-antibody bound to an isolated glycan comprising type I—N-acetyllactosamine comprising target structure, and methods and uses utilizing said complex.... | 05/24/2012 |
| 20120128632 | IDENTITY MARKERS Methods for identifying trichogenic dermal cells, including dermal papilla cells and dermal sheath cells, capable of inducing hair follicle formation when injected into skin are provided. It has been discovered that EGF latrophilin and seven transmembrane domain-contain... | 05/24/2012 |
| 20120128642 | POTENCY MARKERS Methods for identifying trichogenic dermal cells, including dermal papilla cells and dermal sheath cells, capable of inducing hair follicle formation when injected into skin are provided. Biomarkers have been discovered that can be used to detect, identify, and distingu... | 05/24/2012 |
| 20120128697 | NOTCH Inhibition in the Treatment or Prevention of Atherosclerosis The present invention is directed to methods of treating or preventing atherosclerosis and other cardiovascular diseases by administering agents that inhibit or modulate the NOTCH signaling pathway. In addition, the invention encompasses methods for assaying compounds f... | 05/24/2012 |
| 20120107840 | Methods for Label Free Testing of Cells The invention provides methods of detecting activation of an immune cell, methods for detecting blocking or enhancing properties of a test reagent or stimuli on activation of one or more immune cells or platelets, methods for selecting hybridomas producing antibodies to... | 05/03/2012 |
| 20120108662 | COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS The present application relates to compositions and the treatment of skin disorders, dry skin, protection of skin in inflammatory events and neurological disorders. The present application more particularly discloses the identification of new genes and metabolic pathway... | 05/03/2012 |
| 20120107318 | METHODS OF ADMINISTERING PIF AGONIST PEPTIDES AND USES THEREOF A novel class of embryo derived peptides are described (Preimplantation factor) that were generated synthetically and were tested on peripheral blood immune cells and shown to block activated but not basal immunity, inhibiting cell proliferation and creating a TH 05/03/2012 | |
| 20120082672 | Botulinum Neurotoxin B Receptors and Use Thereof It is disclosed here that synaptotagmin I (syt I) and synaptotagmin II (syt II) are the cellular receptors for botulinum neurotoxin B (BoNT/B) that mediate the cellular entry and toxicity of BoNT/B. The BoNT/B binding domains of syt I and II are also disclosed. While sy... | 04/05/2012 |
| 20120082675 | INSULIN-LIKE GROWTH FACTOR SIGNALING AND INTEGRIN Interaction between insulin-like growth factor 1 (IGFI) and integrin is involved in integrin-mediated cellular signaling, such as enhanced proliferation of cells expressing integrins, especially integrin alpha v beta 3, alpha 6 beta. 1 and alpha 6. beta. 4. A method for... | 04/05/2012 |
| 20120083000 | Neuropeptide Release Assay For Sodium Channels Methods and compositions for using genetically modified non-human animals are provided, wherein the genetic modification comprises a humanization of the one or more extracellular pore loops of a NaV1.7 channel protein or a complete humanization of an endogeno... | 04/05/2012 |
| 20120083003 | PARKIN SUBSTRATE AND ASSAY The invention provides in vitro, ex vivo, and in vivo assays for Parkin activity, in which Parkin-mediated ubiquitination of a Sept4 protein is measured. The assays may be used to screen for agents that modulate Parkin protein ligase activity.... | 04/05/2012 |
| 20120083519 | Methods For Diagnosing And Treating A Renal Disease In An Individual A method for diagnosing a renal disease in an individual, comprising: a) measuring the level of expression of c-mip in a renal sample of the individual; b) comparing the level of expression of c-mip to a predetermined value; and c) determining therefrom whether the indi... | 04/05/2012 |
| 20120083004 | Diagnostic Method for Celiac Sprue Detection of toxic gluten oligopeptides refractory to digestion and antibodies and T cells responsive thereto can be used to diagnose Celiac Sprue.... | 04/05/2012 |
| 20120084871 | NPC1L1 ORTHOLOGUES The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.... | 04/05/2012 |
| 20120083001 | METHOD FOR TRANSPORTING POTASSIUM IONS FROM FRONT SIDE TO BACK SIDE OF LIPID BILAYER MEMBRANE An object of the present invention is to detect a specific chemical substance with high sensitivity and high precision. By using a specific lipid bilayer membrane, a chemical substance is detected with high sensitivity and high precision. Here, the specific lipid bilaye... | 04/05/2012 |
| 20120083442 | MYOSTATIN BINDING AGENTS The present invention provides binding agents comprising peptides capable of binding myostatin and inhibiting its activity. In one embodiment the binding agent comprises at least one myostatin-binding peptide attached directly or indirectly to at least one vehicle such ... | 04/05/2012 |
| 20120083002 | Methods For Modulating The Development Of Dopamine Neuron By The Dopamine D2 Receptor And Compositions Thereof The present invention relates to a composition for modulating the activation of Nurr1, the composition comprising an agonist or an antagonist of a dopamine D2 receptor, methods for modulating the activation of Nurr1 by the dopamine D2 receptor, a method and composition ... | 04/05/2012 |
| 20120070460 | DENDRITIC CELL MODULATORY MOLECULE The present invention provides a dendritic cell modulatory molecule which modulates, and preferable inhibits, the differentiation and maturation of mammalian dendritic cells. The invention also provides pharmaceutical compositions comprising the dendritic cell modulator... | 03/22/2012 |
| 20120071418 | Inhibitors of Human EZH2 and Methods of Use Thereof The invention relates to inhibition of wild-type and certain mutant forms of human histone methyltransferase EZH2, the catalytic subunit of the PRC2 complex which catalyzes the mono- through tri-methylation of lysine 27 on histone H3 (H3-K27). In one embodiment the inhi... | 03/22/2012 |
| 20120070846 | METHODS FOR DETECTING MOLECULE-MOLECULE INTERACTIONS WITH A SINGLE DETECTION CHANNEL A single molecule or molecule complex detection method is disclosed in certain aspects, comprising nano- or micro-fluidic channels.... | 03/22/2012 |
| 20120070847 | Method For Detecting And Purifying Pancreatic Beta Cells The invention is based, in part, on the discovery that a polypeptide, referred to herein as Betacam, is selectively expressed on the surface of pancreatic islet cells, Thus, in one aspect, the invention is directed to compositions comprising Betacam or that can be used ... | 03/22/2012 |
| 20120073001 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS The invention features therapeutic compositions comprising agents useful for the treatment or prevention of pruritis, and methods useful for identifying such agents.... | 03/22/2012 |
| 20120053185 | METHOD TO TREAT MELANOMA IN BRAF INHIBITOR-RESISTANT SUBJECTS Methods to treat cancer patients, especially melanoma patients, who have BRAF mutations and have become resistant to BRAF mutant kinase inhibitors employ inhibitors of multiple receptor tyrosine kinases. In addition, methods are described for identifying pharmaceutical ... | 03/01/2012 |
| 20120053117 | PHARMACEUTICAL COMPOSITION, DRUG SCREENING METHOD AND METHOD FOR TREATING MALARIA The present invention relates to the use of serpentine receptors existent in parasites of genus Plasmodium for treating malaria.... | 03/01/2012 |
| 20120045391 | Formulations Targeting IGFBP7 for Diagnosis and Therapy of Cancer The invention relates to antibodies or fragments thereof specific for insulin-like growth factor binding protein-7 (IGFBP7). A method of raising anti-IGFBP7 single domain antibodies is also disclosed and specific antibody clones are described, along with their binding c... | 02/23/2012 |
| 20120045394 | HUMAN AND MOUSE TARGETING PEPTIDES IDENTIFIED BY PHAGE DISPLAY The present invention concerns methods and compositions for in vivo and in vitro targeting. A large number of targeting peptides directed towards human organs, tissues or cell types are disclosed. The peptides are of use for targeted delivery of therapeutic agents, incl... | 02/23/2012 |
| 20120045446 | THERAPEUTIC AGENT FOR DISEASES IN WHICH NEOPLASTIC PROLIFERATION OF PLASMA CELLS OCCURS The present invention provides a therapeutic agent, for diseases in which neoplastic proliferation of plasma cells occurs, which is characterized by containing an anti-human CD48 monoclonal antibody and having cellular cytotoxicity to cells expressing human CD48; and th... | 02/23/2012 |
| 20120045777 | NOVEL GENES ENCODING PROTEINS HAVING PROGNOSTIC, DIAGNOSTIC, PREVENTIVE, THERAPEUTIC, AND OTHER USES The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The inv... | 02/23/2012 |
| 20120045459 | Methods for Treating Autophagy-Related Disorders Methods for treating autophagy-related disorders with agents which modulate expression of the gene encoding tyrosine phosphatase receptor type sigma (PTPRS) or which modulate the biological activity of the PTPRS gene product (PTPsigma). Methods for modulating autophagy ... | 02/23/2012 |
| 20120046217 | TNF-alpha Antagonists Containing IGFBP5 The present invention relates to: TNF-α antagonists containing IGFBP5 protein, variants thereof, or fragments thereof; and the use of the TNF-α antagonists. More specifically, the present invention relates to: a polynucleotide encoding the protein, variants thereof, o... | 02/23/2012 |
| 20120045763 | Antibodies Against Cells of Fetal Origin This invention relates to antibodies that specific bind to fetal CD36+ cells in preference to binding to maternal CD36+ cells and methods for using these antibodies to detect and separate fetal cells from adult biological fluids including maternal peripheral blood.... | 02/23/2012 |
| 20120046233 | MUTATIONS IN THE LNK GENE IN PATIENTS WITH MYELOPROLIFERATIVE NEOPLASMS AND OTHER HEMATOLYMPHOID MALIGNANCIES Aspects of the present invention include methods, compositions and kits for classifying a subject as having or being predisposed to a hematolymphoid neoplasm or malignancy if they harbor a mutation in the LNK gene. Aspects of the present invention also include screening... | 02/23/2012 |
| 20120040374 | METHOD FOR DETECTING RENAL DISEASE COMPRISING MEASURING HUMAN MEGALIN IN URINE This invention provides a diagnostic kit and a diagnostic marker used for diagnosing a renal disease. This invention also provides a method for detecting a renal disease comprising measuring at least one type of human megalin existing in urine selected from among full-l... | 02/16/2012 |
| 20120040858 | BIOMARKERS FOR STROKE Biomarkers for stroke and methods for their detection are disclosed. In one aspect, the present application discloses biomarkers for the diagnosis of stroke in a subject. In another aspect, the application discloses a method for the diagnosis of stroke in a subject. The... | 02/16/2012 |
| 20120040894 | Mini-Hepcidin Peptides and Methods of Using thereof Disclosed herein are peptides which exhibit hepcidin activity and methods of making and using thereof.... | 02/16/2012 |
