Celebrity Inventors
Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
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| Application No. | Application Title | Issue Date |
| 20120129778 | LIGAND THAT BIND TGF-BETA RECEPTOR RII The disclosure provides an anti-TGFbetaRII immunoglobulin single variable domain. The disclosure also provides a polypeptide, ligand or pharmaceutical composition for treating a disease associated with TGFbeta signaling and a disease selected from the group of: tissue f... | 05/24/2012 |
| 20120129218 | COFILIN KNOCKDOWN HOST CELLS AND USES THEREOF The present invention relates to a host cell comprising a cofilin-specific small interfering RNA (siRNA) sequence. The host cell may further comprise a nucleic acid encoding a recombinant protein. The present invention also relates to a method for producing a recombinan... | 05/24/2012 |
| 20120131687 | AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT VOLTAGE-GATED POTASSIUM CHANNEL ACTIVITY The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect voltage-gated potassium channel; a method for assaying pesticidal activity of a test substance, which comprise... | 05/24/2012 |
| 20120129217 | POLYPEPTIDE EXPRESSION IN CILIATES This invention is directed to methods for recombinant polypeptide production and, in particular, methods and products for the production of recombinant polypeptides in ciliates.... | 05/24/2012 |
| 20120107355 | METHOD OF RAPIDLY PRODUCING IMPROVED VACCINES FOR ANIMALS A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on... | 05/03/2012 |
| 20120110685 | MODULAR DNA-BINDING DOMAINS AND METHODS OF USE The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specificall... | 05/03/2012 |
| 20120107873 | Method of Producing a Sweet Protein The present invention relates to a method of producing a recombinant sweet protein in a filamentous fungus. The invention also relates to isolated polynucleotides encoding the sweet protein and to nucleic acid constructs, vectors, and host cells comprising the polynucle... | 05/03/2012 |
| 20120107362 | NEUROTOXINS EXHIBITING SHORTENED BIOLOGICAL ACTIVITY The present invention relates to the pharmaceutical field. Specifically, it contemplates a polynucleotide encoding a neurotoxin polypeptide exhibiting a reduced duration of the biological effect in a subject, wherein the polypeptide comprises at least one degradation si... | 05/03/2012 |
| 20120107372 | RECOMBINANT GELATINS The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBEmonomersequence that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anc... | 05/03/2012 |
| 20120107872 | THERMOSTABLE TRICHODERMA CELLULASE Described are compositions and methods relating to the thermostable fungal cellulase enzyme, EGV, and Trichoderma host cells having a modification comprising or consisting essentially of disruption or deletion of nucleotide(s) for expression of this cellulose, wh... | 05/03/2012 |
| 20120110694 | PLANT MYB TRANSCRIPTION FACTOR HOMOLOGS This invention relates to an isolated nucleic acid fragment encoding a Myb-related transcription factor. The invention also relates to the construction of a chimeric gene encoding all or a portion of the Myb-related transcription factor, in sense or antisense orientatio... | 05/03/2012 |
| 20120107871 | METHOD OF PRODUCING HUMAN IGG ANTIBODIES WITH ENHANCED EFFECTOR FUNCTIONS A method for generating human IgG1 antibodies with enhanced Fc effector function is disclosed. In practicing the method, an IgG1 Fc look-through mutagenesis (LTM) coding library directed at four receptor-contact regions of the Fc CH2 por... | 05/03/2012 |
| 20120107874 | Modified Host Cells and Uses Thereof The present disclosure provides compositions and methods comprising cells producing glycoproteins with variant glycosylation patterns. The methods and compositions may be used in producing antibodies and proteins of therapeutic value.... | 05/03/2012 |
| 20120107856 | New Fungal Production System The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain... | 05/03/2012 |
| 20120107828 | METHOD FOR IDENTIFYING A SUBPOPULATION OF MAMMALIAN CELLS WITH DISTINCTIVE RIBOSOME TRANSLATION PROFILES The present invention generally relates to subpopulations of mammalian cells with distinctive ribosome translational profiles, i.e. translational activities. The present invention further relates to methods for identifying and isolating such cells, kits comprising the s... | 05/03/2012 |
| 20120108790 | Truncated Somatostatin Receptors The present invention is directed to fusion proteins that can be used to assay gene transfer and expression both in vitro and in vivo. The fusion proteins contain a reporter protein, e.g. a somatostatin receptor, fused to a second protein, which may be a protein fusion ... | 05/03/2012 |
| 20120107343 | PRODUCTION OF RECOMBINANT PROTEINS IN CILIATES AND USES THEREOF This invention is directed to methods for recombinant polypeptide production and, in particular, methods and products for the production and purification of recombinant proteins in ciliates.... | 05/03/2012 |
| 20120107244 | MONOMERIC VARIANTS OF THE TETRAMERIC eqFP611 Monomeric eqFP611 variants exhibit red fluorescent properties and DNA encoding monomeric eqFP611 variants.... | 05/03/2012 |
| 20120083014 | Nicotiana Benthamiana Plants Deficient in Xylosyltransferase Activity The invention provides Nicotiana benthamiana mutant plants which are incapable of forming xylosyl-structures on glycoproteins. In addition, the invention provides methods for the production of heterologous glycoproteins in said mutant plants.... | 04/05/2012 |
| 20120083442 | MYOSTATIN BINDING AGENTS The present invention provides binding agents comprising peptides capable of binding myostatin and inhibiting its activity. In one embodiment the binding agent comprises at least one myostatin-binding peptide attached directly or indirectly to at least one vehicle such ... | 04/05/2012 |
| 20120084871 | NPC1L1 ORTHOLOGUES The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.... | 04/05/2012 |
| 20120083013 | GLUCOSYLTRANSFERASE SPECIFIC TO POSITION-4 OF FUROFURAN-TYPE LIGNAN, AND POLYNUCLEOTIDE ENCODING SAME The invention provides a polynucleotide encoding a furofuran lignan 4-O-glucosyltransferase, and others. The polynucleotide in accordance with the present invention comprises a polynucleotide consisting of the nucleotide sequence represented by SEQ ID NO: 3 or SEQ ID NO... | 04/05/2012 |
| 20120082622 | Macaca fascicularis CCL17 Isolated polynucleotides encoding Macaca fascicularis CCL17 (CynoCCL17), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed.... | 04/05/2012 |
| 20120070859 | BACTERIAL CELLS, OPTIMIZED NUCLEOTIDE SEQUENCES AND METHODS FOR IMPROVED EXPRESSION OF RECOMBINANT CLOSTRIDIUM DIFFICILE TOXIN B In some embodiments, the present invention provides isolated nucleotide sequences that encode Clostridium difficile toxin B, wherein the isolated nucleotide sequences have been optimized for improved expression of the toxin B in a bacterial cell. Other embodiment... | 03/22/2012 |
| 20120070860 | COMBINATION STIRRER The present patent application describes a stirrer comprising a combination of at least one axially-conveying element and at least one radially-conveying element relative to the rotary shaft of the stirrer wherein the largest diameter of the at least one axially-conveyi... | 03/22/2012 |
| 20120071422 | Therapeutic application of isolated naturally-occuring soluble truncated forms of IL-23 receptor The present invention relates to an isolated naturally-occurring soluble truncated IL-23Rα protein, which is a translated protein resulting from a mRNA splice variant of IL-23Rα. The soluble IL-23Rα proteins (e.g., Δ9 and Δ8,9) represents a novel soluble IL-23Rα p... | 03/22/2012 |
| 20120071631 | Isolation and Characterization of Novel Green Fluorescent Proteins from Copepods The isolation and characterization of two protein isoforms collected green fluorescent copepods is described herein. The new Pontella mimocerami GFP-like isoforms pmimGFP1 and pmimGFP2 of the present invention are quick to mature and rapidly produce a fluorescent... | 03/22/2012 |
| 20120052529 | EPISOMAL EXPRESSION VECTOR FOR METAZOAN CELLS The invention relates to a vector comprising an origin of replication for episomal maintenance in a metazoan cell, a gene for episomal maintenance in the metazoan cell, and a telomeric polynucleotide sequence. The vector can be used for episomal expression of RNA and po... | 03/01/2012 |
| 20120052530 | Combinatorial DNA Library for Producing Modified N-Glycans in Lower Eukaryotes The present invention relates to eukaryotic host cells having modified oligosaccharides which may be modified further by heterologous expression of a set of glycosyltransferases, sugar transporters and mannosidases to become host-strains for the production of mammalian,... | 03/01/2012 |
| 20120054906 | Method for Preparation and Purification of Recombinant Proteins The present invention relates to a method for the production, isolation, and purification of a recombinant protein, more particularly, to a method for isolating and purifying a foreign protein stably using Anti-Freeze Protein (AFP), thereby producing the protein. The pr... | 03/01/2012 |
| 20120053232 | ISOLATED GENOMIC POLYNUCLEOTIDE FRAGMENTS FROM THE p15 REGION OF ISOLATED GENOMIC POLYNUCLEOTIDE FRAGMENTS FROM THE p15 REGION OF CHROMOSOME 11 ENCODING HUMAN TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 (TSSC4) Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human and tumor suppressing subtransferable candidate 4 (TSSC4) and methods of use.... | 03/01/2012 |
| 20120046184 | METHOD FOR THE SELECTIVE CONCENTRATION OF A SPECIFIC LOW ABUNDANCE BIOMOLECULE Provided herein is a method for the isolation or removal of a cellular component from a cell that comprises the steps of applying a pulse of nanoparticles to the cell, allowing the nanoparticles to traffic through the cell for a period of time sufficient to allow the na... | 02/23/2012 |
| 20120047605 | Novel Bacillus thuringiensis Gene with Lepidopteran Activity The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the invention provide... | 02/23/2012 |
| 20120047606 | Novel Bacillus thuringiensis Gene with Lepidopteran Activity The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the invention provide... | 02/23/2012 |
| 20120045447 | T CELL COSTIMULATING POLYPEPTIDES AND USES THEREOF A polypeptide (8F4 molecule) with a T-cell costimulating biological activity is disclosed, as well as monoclonal antibodies against the 8F4 molecule and hybridoma cells which produce the monoclonal antibodies, the use as medicaments of substances which inhibit the biolo... | 02/23/2012 |
| 20120045473 | Biomolecule Surface Display and Uses Thereof A vaccine for the treatment or prevention of a disease in a subject, wherein said disease is associated with an avian influenza virus, and wherein said vaccine comprises an expression vector comprising a nucleic acid encoding a hemagglutinin peptide, such that in use sa... | 02/23/2012 |
| 20120045777 | NOVEL GENES ENCODING PROTEINS HAVING PROGNOSTIC, DIAGNOSTIC, PREVENTIVE, THERAPEUTIC, AND OTHER USES The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The inv... | 02/23/2012 |
| 20120045793 | EXPRESSION CONSTRUCTS COMPRISING FUNGAL PROMOTERS The present invention provides promoters derived from a filamentous fungus. These promoters have application in the fields of molecular biology, microbiology, fungal genetics and production of biofuels and other products.... | 02/23/2012 |
| 20120047607 | Novel Bacillus thuringiensis Gene with Coleopteran Activity The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Coleoptera. Particular embodiments of the invention provide ... | 02/23/2012 |
| 20120045795 | METHOD FOR PRODUCING A CELL CAPABLE OF HIGH-YIELD PRODUCTION OF HETEROPROTEINS The present invention provides a cell capable of high-yield production of polypeptides and a method for producing the same. The present invention relates to a method for producing a cell capable of high-yield production of a desired polypep... | 02/23/2012 |
