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| Application No. | Application Title | Issue Date |
| 20110159168 | Non-transgenic Tomato Varieties Having Increased Shelf Life Post-Harvest Due to Alterations in Beta-Galactosidase 4 The present invention provides a series of independent human-induced, non-transgenic mutations found in at least one tomato β-galactosidase 4 gene, tomato plants having these mutations in at least one of their tomato β-galactosidase 4 genes, and a method of creating a... | 06/30/2011 |
| 20110159481 | Solid-phase chelators and electronic biosensors Methods for sequencing nucleic acids are presented. Sequencing is accomplished through the chemical amplification of the products of DNA synthesis and the detection of the chemically amplified products. In embodiments of the invention, a substrate is provided having a p... | 06/30/2011 |
| 20110159483 | CYANINE COMPOUNDS, COMPOSITIONS INCLUDING THESE COMPOUNDS AND THEIR USE IN CELL ANALYSIS A compound having the general formula I or a conjugate thereof, wherein various groups are as defined in the specification. A composition includes: (i) a compound having the general formula I or a conjugate thereof; and (ii) at least one surfactant selected from cationi... | 06/30/2011 |
| 20110159478 | METHOD FOR SCREENING DRUG CANDIDATES BY USING DOMAIN PROTEIN The present invention relates to a method for screening and discovering bioactive materials using specifically selected protein domains interacting with specific intracellular proteins, and more particularly, to (1) a screening method including confirmation of changes i... | 06/30/2011 |
| 20110159480 | CELL-BASED SCREENING ASSAY TO IDENTIFY MOLECULES THAT STIMULATE IFN-ALPHA/BETA TARGET GENES A method using cells transformed with a construct containing a reporter gene operatively-linked to an interferon stimulated response element for identifying an agent, such as a chemical compound, peptide or polypeptide, which exhibits an interferon-like activity on the ... | 06/30/2011 |
| 20110159479 | GENETIC POLYMORPHISMS IN THE CYTOCHROME P450 GENE WITH CLOPIDOGREL RESISTANCE The present invention relates to a method for predicting the resistance of a human subject to clopidogrel, which comprises detecting the presence or absence of a A allele at position 636 of exon 4 in the CYP2C19 gene, wherein the presence of the A allele is indicative o... | 06/30/2011 |
| 20110159484 | APPARATUS AND METHOD OF AUTHENTICATING PRODUCT USING POLYNUCLEOTIDES A method of authenticating a product includes; hybridizing a target polynucleotide which is associated with the product and which includes a first target region and a second target region adjacent to the first target region with a probe polynucleotide that comprises a f... | 06/30/2011 |
| 20110159482 | METHOD FOR DETECTING MULTIPLE SMALL NUCLEIC ACIDS The present invention discloses a method for simultaneously detecting multiple small nucleic acids, which comprises steps: mixing a specimen, fluorescent probes, and bridge nucleic acids having different lengths to form a tested liquid; hybridizing the mixed short nucle... | 06/30/2011 |
| 20110151445 | ALLELIC DISORDERS CAUSED BY MUTATIONS IN TRPV4 The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4 (TRPV4). In particular, mutations are detected in TRPV4 to detect diseases such as scapuloperoneal spinal muscula... | 06/23/2011 |
| 20110151438 | Methods of Analysis of Methylation Methods for determining the methylation status of a plurality of cytosines are disclosed. In some aspects genomic DNA target sequences containing CpGs are targeted for analysis by multiplex amplification using target specific probes that can be specifically degraded pri... | 06/23/2011 |
| 20110151443 | MARKER FOR GASTRIC CANCER Methods for detecting and assessing the progress and prognosis of gastric cancer are presented. Primers and probes for use in the methods are also disclosed as are methods for suppressing gastric cancer and kits for implementing the methods.... | 06/23/2011 |
| 20110151442 | Direct Molecular Diagnosis of Fetal Aneuploidy Methods and materials for detection of aneuploidy and other chromosomal abnormalities using fetal tissue are disclosed. Results can be obtained rapidly, without cell culture. The method uses digital PCR for amplification and detection of single target sequences, allowin... | 06/23/2011 |
| 20110151441 | ENDPOINT TAQMAN METHODS FOR DETERMINING ZYGOSITY OF CORN COMPRISING TC1507 EVENTS A method for zygosity analysis of the maize Cry1F event TC1507 is provided. The method provides TC1507 event-specific and maize endogenous reference gene-specific primers and TaqMan probe combinations for use in an endpoint biplex TaqMan PCR assay capable of producing r... | 06/23/2011 |
| 20110151444 | METHOD FOR DETECTION OF AN RNA MOLECULE, A KIT AND USE RELATED THEREFOR Described is a method for the detection of a RNA molecule, the method involving the steps of providing a sample containing the RNA molecule; hybridizing to the RNA molecule a first polynucleotide; extending the first polynucleotide to generate a first strand cDNA; hybri... | 06/23/2011 |
| 20110151440 | Screening for Arthrogryposis Multiplex in Bovines Provided are methods, materials and kits for analyzing DNA samples from bovine to determine whether the animal is a recessive carrier of a genetic mutation that is associated with arthrogryposis multiplex (AM). DNA-containing samples are analyzed by genetic testing to d... | 06/23/2011 |
| 20110154525 | Maize event DP-040416-8 and methods for detection thereof The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-040416-8 event based on the DNA sequence of the recombinant construct inserted into the maize genome and ... | 06/23/2011 |
| 20110154526 | Maize event DP-043A47-3 and methods for detection thereof The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-043A47-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and ... | 06/23/2011 |
| 20110151439 | SYSTEM AND METHOD FOR THE RAPID IDENTIFICATION OF BIOLOGICAL AND CHEMICAL ANALYTES A system and method for the rapid identification of biological and chemical analytes that includes an enzyme substrate compound; an aptamer recognizing an analyte; and a recognition probe that comprises a first terminus operatively coupled to an enzyme catalyzing the en... | 06/23/2011 |
| 20110154524 | Maize event DP-032316-8 and methods for detection thereof The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-032316-8 event based on the DNA sequence of the recombinant construct inserted into the maize genome and ... | 06/23/2011 |
| 20110142913 | COMPOSITION AND METHOD FOR TREATING ATHEROSCLEROSIS, METHOD FOR DETERMINING IF A SUBJECT HAS ATHEROSCLEROSIS AND METHOD OF SCREENING AN ANTI-ATHEROSCLEROTIC DRUG The invention provides a method for determining if a subject has atherosclerosis, including: determining an endogenous microRNA-195 expression level of a subject suspected of having atherosclerosis; and comparing the endogenous microRNA-195 expression level of the subje... | 06/16/2011 |
| 20110136104 | MULTIPLEXED QUANTITATIVE PCR END POINT ANALYSIS OF NUCLEIC ACID TARGETS Certain embodiments of the present invention are directed to one pot multiplexed quantitative PCR methods for end point analysis of a plurality of nucleic acid targets in a complex sample without user intervention, and to various encoded particles on which are immobiliz... | 06/09/2011 |
| 20110136103 | AUTOANTIBODY ENHANCED IMMUNOASSAYS AND KITS The present disclosure provides immunoassays and kits for detection or quantification of an analyte of interest in a test sample that potentially contains endogenously produced autoantibodies reactive with the analyte.... | 06/09/2011 |
| 20110136105 | METHODS OF QUANTIFYING NUCLEIC ACIDS The present invention provides a method of detecting or quantifying a target nucleic acid by using fluorescently labeled oligonucleotide probes that do not rely on secondary structure or enzymatic action. The present invention provides improved methods of detecting or q... | 06/09/2011 |
| 20110130337 | POLYMORPHISMS ASSOCIATED WITH PARKINSON'S DISEASE The invention provides human polymorphisms that are associated with Parkinson's disease (PD). Also disclosed are compositions and methods for use in diagnostics, prognostics, prevention, treatment and/or study of PD.... | 06/02/2011 |
| 20110129818 | ASSAY FOR CARDIAC TROPONIN-T (cTnT) The present disclosure describes immunoassays for detecting cardiac troponin-T (cTnT) in a test sample, and in particular immunoassays and kits for detecting cTnT in a test sample suspected of containing substances that may interfere with the determination of cTnT, such... | 06/02/2011 |
| 20110129817 | BLOOD TRANSCRIPTIONAL SIGNATURE OF ACTIVE VERSUS LATENT MYCOBACTERIUM TUBERCULOSIS INFECTION The present invention includes methods, systems and kits for distinguishing between active and latent mycobacterium tuberculosis infection in a patient suspected of being infected with Mycobacterium tuberculosis, the method including the steps of obtaining... | 06/02/2011 |
| 20110126315 | NOVEL SELECTION MARKER GENE AND USE THEREOF A DNA construct including a gene which is operably linked to a seed-specific promoter and which encodes a fusion protein of a seed protein and a fluorescent protein is used. This provides a technique for obtaining a target transformant in a relatively short time without... | 05/26/2011 |
| 20110124700 | SYSTEMS AND METHODS OF CANCER STAGING AND TREATMENT Methods of assessing the sensitivity of a cancer cell to a tyrosine kinase inhibitor are disclosed. Such methods include assessing the expression of miR-497 and correlating reduced expression with sensitivity to the tyrosine kinase inhibitor. Also disclosed are methods ... | 05/26/2011 |
| 20110126318 | SUCROSE TRANSPORTER GENES FOR INCREASING PLANT SEED LIPIDS This invention relates to polynucleotide sequences encoding SUT2 or SUT4 sucrose transporter genes. Methods for increasing seed oil content and evaluating increased oil content in a plant seed are described. The compositions and methods disclosed herein employ a variety... | 05/26/2011 |
| 20110124518 | METHODS AND COMPOSITIONS FOR THE ANALYSIS OF BIOLOGICAL MOLECULES Provided herein are compositions and methods for analysis of nucleic acids, including, methods and compositions for genotyping, haplotyping, sequencing and performing other genetic and epigenetic analyses on nucleic acids, for example. In some embodiments, methods and c... | 05/26/2011 |
| 20110124517 | Process for Determining the Genotype from a Biological Sample Containing Nucleic Acids of Different Individuals The present Invention relates to a process for determining the genotype of one or more individuals from a biological sample which contains nucleic acids from different individuals, in particular a process for determining the number of copies of a predetermined sequence,... | 05/26/2011 |
| 20110124554 | Fibrosuppressant Biotherapeutics The invention relates to IHG-1 (induced by high glucose-1) a novel gene which encodes a protein that amplifies fibrotic responses in in vitro and in vivo models of fibrotic disorders and in human diabetic nephropathy. In particular the invention relates to modifications... | 05/26/2011 |
| 20110126325 | RECOMBINANT CELLS AND METHODS FOR HYDROXYLATING FATTY ACIDS The present invention relates to enzymes which possess hydroxylase activity, in particular 42 hydroxylase activity, that can be used in methods of synthesizing modified fatty acids.... | 05/26/2011 |
| 20110123989 | METHOD FOR THE DETECTION OF SCHIZOPHRENIA RELATED GENE TRANSCRIPTS IN BLOOD The present invention is directed to detection and measurement of gene transcripts and their equivalent nucleic acid products in blood. Specifically provided is analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using gene-specific a... | 05/26/2011 |
| 20110123991 | ISOTHERMAL NUCLEIC ACID AMPLIFICATION An isothermal process for amplifying a nucleic acid target molecule that relies on an upstream primer, a downstream primer, a strand invasion system and an oligonucleotide, wherein the upstream and downstream primers are not substrates for the strand invasion system dur... | 05/26/2011 |
| 20110123987 | METHODS FOR THE DIAGNOSIS OF ONCOLOGICAL DISORDERS USING EPIMETABOLIC SHIFTERS, MULTIDIMENSIONAL INTRACELLULAR MOLECULES, OR ENVIRONMENTAL INFLUENCERS Methods and formulations for diagnosing onocological disorders in humans using epimetabolic shifters, multidimensional intracellular molecules or environmental influencers are described.... | 05/26/2011 |
| 20110123986 | METHODS FOR THE DIAGNOSIS OF METABOLIC DISORDERS USING EPIMETABOLIC SHIFTERS, MULTIDIMENSIONAL INTRACELLULAR MOLECULES, OR ENVIRONMENTAL INFLUENCERS Methods and formulations for diagnosing metabolic disorders in humans using epimetabolic shifters, multidimensional intracellular molecules or environmental influencers are described.... | 05/26/2011 |
| 20110123990 | Methods To Predict Clinical Outcome Of Cancer The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers. More particularly, the invention relates to the identification of genes, or sets of ... | 05/26/2011 |
| 20110123988 | ANTISENSE COMPOUNDS AND METHODS FOR DIAGNOSTIC IMAGING Compounds comprising a diagnostic or therapeutic moiety can be retained inside a cell by conjugating the moiety to at least one PNA that is targeted to the transcripts from a gene of interest. The diagnostic or therapeutic moiety is also conjugated to at least one targe... | 05/26/2011 |
| 20110123992 | PROBE, PROBE SET, PROBE CARRIER, AND TESTING METHOD A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly d... | 05/26/2011 |
