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| Application No. | Application Title | Issue Date |
| 20120129190 | ENSEMBLE-DECISION ALIQUOT RANKING Provided herein, among other aspects, are methods and apparatuses for ranking aliquots from a suspension containing bioparticles. In certain embodiments, the bioparticles may be cells, organelles, proteins, DNAs, debris of biological origin, microbeads coated with biolo... | 05/24/2012 |
| 20120129714 | QUANTITATIVE MULTIPLEXED IDENTIFICATION OF NUCLEIC ACID TARGETS Methods and systems for detecting a target nucleic acid using the quantitative capabilities of real-time nucleic acid amplification systems and the multiplexing capabilities of hybridization systems, comprising: identifying a conservative sequence and a distinctive sequ... | 05/24/2012 |
| 20120129193 | DEVICE AND METHOD FOR ANALYSING CELLS There is provided a carrier substrate for nonspecific immobilization of living bacterial and/or eukaryotic cells, especially of animal cells, which can be present as single cells, cell agglomerates or tissue sections. The surface of the carrier substrate is provided at ... | 05/24/2012 |
| 20120129157 | Methods and Devices for Rapid Detection and Identification of Live Microorganisms by Aptamers and/or Antibodies Immobilized on Permeable Membranes The invention provides methods, devices and kits for rapid detection and identification of one or more live target microorganisms in a liquid sample or grown on plates containing nutrient media. The invention includes mixing one or more target microorganisms with one or... | 05/24/2012 |
| 20120129192 | Apparatus and Methods for Detection of Tumor Cells in Blood In one embodiment, the present invention provides the description of an inexpensive and disposable handheld device for detecting Circulating tumor cells (CTC) in blood called a handheld CTC detector (HCTCD). The HCTCD is capable of detecting less than 1 CTC per m... | 05/24/2012 |
| 20120107818 | DETECTION OF MULTIPLE NUCLEIC ACID SEQUENCES IN A REACTION CARTRIDGE The present invention relates to a method for amplifying and detecting nucleic acid sequences in a reaction cartridge comprising the following steps, (i) providing a sample comprising at least one nucleic acid molecule, (ii) in a first reaction chamber of the cartridge ... | 05/03/2012 |
| 20120107845 | Disrupting FCRN-Albumin Interactions Provided herein are, inter alia, methods for identifying a candidate compound for treating the toxic effects of compounds or molecules that bind to albumin in a subject. The methods include identifying test compounds that inhibit the binding between FcRn and albumin.... | 05/03/2012 |
| 20120107822 | METHOD OF DELIVERING PCR SOLUTION TO MICROFLUIDIC PCR CHAMBER The present invention relates to systems and methods of performing in-line mixing of assay components and delivery of such mixed components into microfluidic channels. In one aspect, a method of delivering mixed assay components is provided which comprises causing an un... | 05/03/2012 |
| 20120107811 | BURSTABLE LIQUID PACKAGING AND USES THEREOF The present invention relates to systems, devices, and methods for performing biological and chemical reactions. In particular, the present invention relates to the use of burstable liquid packaging for delivery of reagents to biological and chemical assays.... | 05/03/2012 |
| 20120082978 | Cell Analysis On Microfluidic Chips The present invention provides for a method of implementing fluorescent in situ hybridization (FISH) or other cellular analysis processes using intact cells within a microfluidic, chip-based, apparatus. The invention further provides for a method of cellular immobilizat... | 04/05/2012 |
| 20120083028 | DEVICE FOR FECAL OCCULT BLOOD TEST A devise for fecal occult blood test comprises a first and a second casings, a sampling portion extending from the first casing, a specimen processing portion, at least a testing portion and a packing cylindrical member. The packing cylindrical member is coupled between... | 04/05/2012 |
| 20120082977 | ARTICLES WITH MATRIX COMPRISING A CELL EXTRACTANT AND BIODETECTION METHODS THEREOF Articles are provided for the detection of cells in a sample. The articles include a release element. The release element comprises an encapsulating agent and a cell extractant. The release element controls the release of the cell extractant into a liquid mixture contai... | 04/05/2012 |
| 20120082361 | METHOD In one aspect the present invention provides a method for selecting a cell or cell colony which produces a polypeptide of interest, comprising a) providing a medium comprising cells and a detection agent, wherein the detection agent is associated with a detectable signa... | 04/05/2012 |
| 20120082985 | Sensing And Identifying Biological Samples On Microfluidic Devices A method, system, and apparatus for analysis of a biological sample includes receiving the sample, wherein the sample includes deoxyribonucleic acid (DNA), lysing the sample to obtain access to the DNA included in the sample, purifying the DNA in the sample to isolate t... | 04/05/2012 |
| 20120070822 | METHOD FOR SIGNAL AMPLIFICATION DURING LATERAL-FLOW ANALYSIS Provided is a signal amplifying method in a lateral flow analysis with high sensitivity, in which gold ions and a reductant are added and react to a seed of gold nano particles to amplify a signal, and a lateral flow analysis device using the same.... | 03/22/2012 |
| 20120071346 | GENE-BASED ALGORITHMIC CANCER PROGNOSIS The present invention is related to the methods and systems for prognosis determination in tumor samples, by measuring gene expression in a tumor sample and applying a gene-expression grade index (GGI) or a relapse score (RS) to yield a number c risk score.... | 03/22/2012 |
| 20120070820 | Probes and Methods for Hepatitis C Virus Typing Using Multidimensional Probe Analysis This invention provides compositions and methods for HCV typing, e.g., genotyping and/or subtyping. The compositions and methods of the invention can be used to assign an HCV isolate to one of at least five HCV types (for example, selected from types 1, 2, 3, 4, 5 or 6)... | 03/22/2012 |
| 20120071342 | SYSTEM AND METHOD FOR DETECTING MULTIPLE MOLECULES IN ONE ASSAY A rapid diagnostic system that delivers a panel of serologic assay results using a small amount of blood, serum, or plasma is described. The system includes a disposable cartridge and a reader instrument, based on planar waveguide imaging technology. The cartridge incor... | 03/22/2012 |
| 20120070833 | LATERAL FLOW MICROFLUIDIC ASSAYING DEVICE AND RELATED METHOD Provided herein is a microfluidic device and related method for controlling flow of different fluid components of a fluid. The microfluidic device comprises an input channel, focusing channel and an assaying channel. The microfluidic device is adapted to separate a flui... | 03/22/2012 |
| 20120071327 | INDEXING OF NUCLEIC ACID POPULATIONS The invention relates to a method for acquisition of genetic information, in particular for personalized medicine.... | 03/22/2012 |
| 20120053088 | MICROFLUIDIC TEST MODULE FOR BIOCHEMICAL PROCESSING AND ANALYSIS A test module for biochemical processing and analysis, the test module having an outer casing dimensioned for hand-held portability, the outer casing having a receptacle for receiving biochemical liquid, and, a reagent reservoir containing a reagent for addition to the ... | 03/01/2012 |
| 20120052560 | SYSTEM AND METHOD FOR SERIAL PROCESSING OF MULTIPLE NUCLEIC ACID ASSAYS The present invention relates generally to systems and methods for the rapid serial processing of multiple nucleic acid assays. More particularly, the present invention provides for the real time processing of nucleic acid during polymerase chain reaction (PCR) and ther... | 03/01/2012 |
| 20120052562 | TEST MODULE WITH MICROFLUIDIC DEVICE HAVING LAMINAR STRUCTURE AND SAMPLE RECEPTACLE A test module having an outer casing for hand held portability, and, a microfluidic device for processing a biological sample mounted in the outer casing, the microfluidic device having a lab-on-a-chip (LOC) device with a cap, the LOC device having a supporting substrat... | 03/01/2012 |
| 20120052491 | CELL ANALYZER AND CELL ANALYZATION METHOD A cell analyzer includes: a measuring portion which measures cells that are nuclear stained; a displaying portion which displays a histogram of a fluorescence intensity by using a result of the measurement by the measuring portion; and a determining unit which obtains a... | 03/01/2012 |
| 20120052563 | OPTICAL SYSTEM FOR HIGH RESOLUTION THERMAL MELT DETECTION This invention relates to systems and methods for imaging sample materials within a microfluidic device during an assay reaction process. In accordance with certain aspects of the invention, images are formed with a pixel array and a region of interest (“ROI”) is de... | 03/01/2012 |
| 20120053078 | BIOMATERIAL CONSTRUCT, ITS PRODUCING METHOD, BIOMATERIAL SUPPORT, TARGET MATERIAL PURIFYING METHOD, AFFINITY CHROMATOGRAPHY CONTAINER, SEPARATION CHIP, ANALYZING METHOD AND ANALYZING SEPARATOR FOR TARGET MATERIAL, BIOMATERIAL COMPLEX, AND ITS SUPPORT, SENSOR CHIP, SOLID SUPPORT WITH BIOMATERIAL FIXED THEREON A biomaterial structure containing a larger amount of biomaterial than the conventional art with maintaining the reactivity of the biomaterial is provided by linking particulate lumps in which the biomaterial is bound with a compound capable of binding to the biomateria... | 03/01/2012 |
| 20120052522 | Apparatus And Method For The Study Of Metabolism Embodiments of the present invention feature methods and apparatus in which fluids circulating between a plurality of vessels containing different cell types or tissues are monitored for metabolites following the introduction of a sample.... | 03/01/2012 |
| 20120045757 | APPARATUS AND METHODS FOR ANALYSING FLUORESCENT PARTICLES According to an embodiment of the invention, an apparatus to detect fluorescence from a sample is disclosed. The apparatus comprises a sample plane onto which the sample is arranged, an excitation light unit including at least a light source to illuminate the sample, an... | 02/23/2012 |
| 20120045786 | OPTO-FLUIDIC MICROSCOPE DIAGNOSTIC SYSTEM An image sensor integrated circuit may contain image sensor pixels. Channels containing a fluid with cells or other material may be formed on top of the image sensor. The image sensor pixels may form imagers. Each imager may be located in a respective one of the channel... | 02/23/2012 |
| 20120041274 | CANCER BIOMARKERS Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.... | 02/16/2012 |
| 20120040358 | Biomarker Panel for Diagnosis and Prediction of Graft Rejection Methods are provided for monitoring a subject having a graft for an acute rejection (AR) response, e.g., to predict, to diagnose, and/or to characterize an AR response. In practicing the subject methods, the expression level of at least one gene in a sample from the sub... | 02/16/2012 |
| 20120040445 | GAS-FREE FLUID CHAMBER A Gas-free Fluid chamber for PCR. The present invention relates to a device with a fluid chamber suitable for performing a polymerized chain reaction for gas-free filling. Such devices may be used in the field of e.g. molecular diagnostics.... | 02/16/2012 |
| 20120040446 | PARTICLE AGGLUTINATION IN A TIP An apparatus and a related method for performing particle agglutination reactions in at least one disposable probe tip are disclosed. The at least one probe tip includes a sample cavity for sample acquisition, at least one flanking cavity for the capture of particles by... | 02/16/2012 |
| 20120040334 | Diagnostic Transcript and Splice Patterns of HPV16 in Different Cervical Lesions The present invention relates to a method for differentiating in a subject with HPV16 between (i) a severe form of HPV16 infection and (ii) a mild form of HPV16 infection based on determining the amount of a first gene product and a second gene product in a sample of a ... | 02/16/2012 |
| 20120040354 | METHODS OF CLASSIFYING THE SEVERITY OF DISEASES OR DISORDERS The present invention relates to methods of classifying the severity of a non-specific disease or disorder in a subject, wherein a determined level of YKL-40 is compared to one or more reference levels of YKL-40, and the severity of said non-specific disease or disorder... | 02/16/2012 |
| 20120040447 | MAGNETIC IMMUNODIAGNOSTIC METHOD FOR THE DEMONSTRATION OF ANTIBODY/ANTIGEN COMPLEXES ESPECIALLY OF BLOOD GROUPS The invention relates to a magnetic immunodiagnostic method for the demonstration of antibody-antigen complexes. One such method involves the research and/or identification of antibodies or antigens, preferably anti-antigen antibodies or antigens of a blood group, and c... | 02/16/2012 |
| 20120034685 | ASSAY SYSTEMS FOR DETERMINATION OF SOURCE CONTRIBUTION IN A SAMPLE The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual.... | 02/09/2012 |
| 20120034686 | DEVICES AND METHODS FOR DUAL EXCITATION RAMAN SPECTROSCOPY Spectroscopic analysis systems and methods for analyzing samples are disclosed. An analysis system may contain an electromagnetic radiation source to provide radiation, a spectroscopic analysis chamber to perform a coherent Raman spectroscopy (e.g., stimulated Raman or ... | 02/09/2012 |
| 20120035279 | PROTOCOL FOR SCREENING TRAVELERS Methods for screening a traveler for an evaluation of the traveler's physical condition or health status by obtaining at least one specimen from the traveler and subjecting the specimen to at least one test that is diagnostic for at least one parameter of the physical c... | 02/09/2012 |
| 20120034633 | MAGNETIC IMMUNOSENSOR AND METHOD OF USE The present invention provides apparatus and methods for the rapid determination of analytes in liquid samples by immunoassays incorporating magnetic capture of beads on a sensor capable of being used in the point-of-care diagnostic field.... | 02/09/2012 |
