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Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.

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Class 435/235.1 - VIRUS OR BACTERIOPHAGE, EXCEPT FOR VIRAL VECTOR OR BACTERIOPHAGE VECTOR; COMPOSITION THEREOF; PREPARATION OR PURIFICATION THEREOF; PRODUCTION OF VIRAL SUBUNITS; MEDIA FOR PROPAGATING


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter excluding viral and bacteria-phage vectors,
No. of applications: 1116
Last issue date: 05/24/2012


1                      
Application No.Application TitleIssue Date
20120129154METHODS AND COMPOSITIONS FOR THE DETECTION OF BACTERIAL BLIGHT
Methods and compositions relating to the detection of bacterial blight are provided. In one embodiment, a detection system is provided comprising a phage operable to infect a Pseudomonas cannabina and/or Pseudomonas syringae microorganism, the phage compri...
05/24/2012
20120128713Replication-Defective Flavivirus Vaccine Vectors Against Respiratory Syncytial Virus
Replication-defective vaccine vectors against respiratory syncytial virus (RSV) are disclosed. Corresponding compositions and methods employing the vaccine vectors are also disclosed....
05/24/2012
20120129710METHODS FOR PRODUCING MEMBERS OF SPECIFIC BINDING PAIRS
A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic d...
05/24/2012
20120107350VIRUS-LIKE PARTICLES OF CAPSID PROTEINS FROM HUMAN PAPILLOMAVIRUS TYPE 16/58/18/6/11 AND THE METHOD FOR PREPARATION AND THE USES THEREOF
Five optimized genes of capsid L1 protein from human papillomavirus type 16, 58, 18, 6 and 11, which are modified by using insect's preferred codons and so on. Method for modifying those genes to express more highly in insect cells. Virus-like particle's vaccine composi...
05/03/2012
20120107320ANTIBODIES SPECIFICALLY DIRECTED TO THE SOLUBLE FORM OF CTLA-4
The invention provides materials and methods relating to antibodies specific for the soluble form of CTLA-4 (sCT-LA-4). Such antibodies have been shown to have a strong boosting effect on antigen-specific human immune responses....
05/03/2012
20120107910RECOMBINANT ENVELOPE PROTEIN OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) AND VACCINE CONTAINING THE SAME
The present invention provides a recombinant HIV Env antigenic protein, a virus-like particle and a recombinant HIV virus. The present invention further provides a vaccine comprising the recombinant HIV Env antigenic protein, the virus-like particle or recombinant HIV v...
05/03/2012
20120107358SUBGENOMIC REPLICONS OF THE FLAVIVIRUS DENGUE
The present invention discloses the construction of dengue virus subgenomic replicons containing large deletions in the structural region (C-preM-E) of the genome, which replicons are useful as vaccines to protect against dengue virus infection....
05/03/2012
20120107911RECOMBINANT HEMAGGLUTININ PROTEIN OF INFLUENZA VIRUS AND VACCINE CONTAINING THE SAME
The present invention provides a recombinant hemagglutinin antigenic protein, a virus-like particle and a recombinant influenza virus. The present invention further provides a vaccine comprising the recombinant hemagglutinin antigenic protein, the virus-like particle or...
05/03/2012
20120107355METHOD OF RAPIDLY PRODUCING IMPROVED VACCINES FOR ANIMALS
A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on...
05/03/2012
20120107909NOVEL HIV-2 ISOLATE
The invention provides a novel strain of HIV-2 capable of causing immunodeficiency. The invention also provides compositions comprising the nucleic acids and polypeptides characteristic of this HIV-2 virus, antibodies specific for this HIV-2 virus, methods of using thes...
05/03/2012
20120107357NOVEL DIVERGENT PICORNAVIRUS: COSAVIRUS
Presented herein is the discovery of a new human picornavirus, Cosavirus (previously termed Dekavirus), methods of detecting the Cosavirus and diagnosing Cosavirus infection, methods of treating or preventing Cosavirus infection, and methods for identifying anti-Cosavir...
05/03/2012
20120107912CELL LYSIS DEVICE AND METHODS OF LYSING CELLS OR VIRUSES
A method of lysing at least one of a cell and a virus, the method including: contacting a sample, which includes at least one of a cell and a virus, with a plurality of beads which are disposed in a first chamber to obtain a combination of the sample and the beads; and ...
05/03/2012
20120108466IMMUNOGLOBULIN LIBRARIES
Methods and compositions for the screening and isolation of ligand-binding polypeptides, such as antibodies. In some aspects, methods of the invention enable the isolation of intact soluble antibodies comprising a constant domain. Screening methods that employ genetic p...
05/03/2012
20120082693USE OF PROTEINS AND PEPTIDES ENCODED BY THE GENOME OF A NOVEL SARS-ASSOCIATED CORONAVIRUS STRAIN
The invention relates to the use of proteins and peptides coded by the genome of the isolated or purified strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from sample reference number 031589 and, in particular, to the use of protein S...
04/05/2012
20120083412Composition and Method for Delivery of Substances in a Dry Mode Having a Surface Layer
The present invention generally relates to compositions and methods of delivering substances in a dry mode, wherein the compositions include a surface layer disposed on the outer surface of the composition that is permeable to carbon dioxide and oxygen. The compositions...
04/05/2012
20120052060Human Antibody Molecules For IL-13
Specific binding members, in particular human anti-IL-13 antibody molecules and especially those which neutralise IL-13 activity. Methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, including asthma, atopic dermatitis, a...
03/01/2012
20120052093COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING UTERINE DISEASE
The present invention relates to methods and compositions for preventing and treating uterine disease, and in particular to vaccines and bacteriophage compositions for treating or preventing puerperal metritis, clinical endometritis and/or subclinical endometritis....
03/01/2012
20120052048ANTIBACTERIAL PHAGE, PHAGE PEPTIDES AND METHODS OF USE THEREOF
The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophages F1245/05, F168/08, F170/08, F770/05, F197/08, F86/06, F87s/06 and F91a/06,...
03/01/2012
20120052554GENE DELIVERY SYSTEM AND METHOD OF USE
A recombinant replication competent retrovirus for gene deliver and gene therapy is provided. The recombinant retrovirus has a heterologous nucleic acid sequence, a sequence encoding a cell- or tissue-specific ligand or a sequence for transcriptional targeting, or a com...
03/01/2012
20120045394HUMAN AND MOUSE TARGETING PEPTIDES IDENTIFIED BY PHAGE DISPLAY
The present invention concerns methods and compositions for in vivo and in vitro targeting. A large number of targeting peptides directed towards human organs, tissues or cell types are disclosed. The peptides are of use for targeted delivery of therapeutic agents, incl...
02/23/2012
20120046340Down Regulation of the Gene Expression by Means of Nucleic Acid-Loaded Virus-Like Particles
The present invention relates to compositions of virus-like particles for the introduction of RNA-interference (RNAi-) inducing molecules into eukaryotic cells and methods for the cell type-specific transduction of a plurality of eukaryotic cells with RNAi-inducing mole...
02/23/2012
20120045819BINDING MOLECULES FOR HUMAN FACTOR VIII AND FACTOR VIII-LIKE PROTEINS
It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides b...
02/23/2012
20120039936INTERGENIC REGIONS AS INSERTION SITES IN THE GENOME OF MODIFIED VACCINIA VIRUS ANKARA (MVA)
The present invention relates to novel insertion sites useful for the integration of exogenous sequences into the Modified Vaccinia Ankara (MVA) virus genome. The present invention further provides plasmid vectors to insert exogenous DNA into the genome of MVA. Furtherm...
02/16/2012
20120040329Process For Continuous Production Of Bacteriophage
As bacteriophage use in industrial application grows there is a need for commercial quantities of identified bacteriophage. This invention discloses a continuous flow bacteriophage proliferation process that can provide commercial quantities of desired bacteriophage in ...
02/16/2012
20120040438Novel Porcine Circovirus Type 2B Isolate and Uses Thereof
The present invention relates to the novel Porcine Circovirus type 2 subtype B (PCV2B-Rm) isolate which comprises a short duplication of sequence and is adapted to grow in cell culture and may be propagated at high titres constantly up to 106 TCID50
02/16/2012
20120039921POULTRY VIRAL MATERIALS AND METHODS RELATED THERETO
The present invention provides materials and methods for researching poultry viruses, particularly for researching infectious bronchitis viruses in poultry. Also provided are materials and methods useful for reducing the economic impact that infectious bronchitis diseas...
02/16/2012
20120040439Use of Prokaryote Viruses to Remediate Bio-Fouling
This invention provides a process for control in oil and gas wells and related facilities of prokaryote caused souring, fouling and corrosion by reduction of problematic prokaryotes with naturally occurring lysing organisms, particularly sulfate-reducing prokaryotes by ...
02/16/2012
20120039877E1-MINUS ADENOVIRUSES AND USE THEREOF
The present invention is related to a virus, preferably an adenovirus, characterised in that the virus comprises:
    • a lac...
02/16/2012
20120034262Bovine Herpes Virus-1 Compositions, Vaccines and Methods
The disclosure relates generally to the treatment or prevention of disease in cattle. More particularly, the invention is directed to the production and use of modified bovine herpesvirus 1 (BHV-1) and their use in compositions and vaccines that protect cattle from BHV-...
02/09/2012
20120034676SENECA VALLEY VIRUS BASED COMPOSITIONS AND METHODS FOR TREATING DISEASE
The present invention relates to a novel RNA picornavirus that is called Seneca Valley virus (“SVV”). The invention provides isolated SVV nucleic acids and proteins encoded by these nucleic acids. Further, the invention provides antibodies that are raised aga...
02/09/2012
20120034677MICROORGANISM CULTURE DEVICE AND METHOD OF OPERATION THEREOF
The invention is directed to a microorganism culture device (100), such as a micro fluidic cell culture device. The device comprises an open chamber (10), wherein microorganisms are likely to be deposited within a liquid for subsequent study. The open cham...
02/09/2012
20120034264INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising (avian pandemic) influenza hemagglutinin and neuraminidase variants are provided....
02/09/2012
20120034265INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided....
02/09/2012
20120028357AAV VECTORS PRODUCED IN INSECT CELLS
The present invention relates to the production of adeno-associated viral vectors in insect cells. The insect cells therefore comprise a first nucleotide sequence encoding the adeno-associated virus (AAV) capsid proteins, whereby the initiation codon for translation of ...
02/02/2012
20120028880VEGFR-1/NRP-1 TARGETING PEPTIDES
The present invention concerns the fields of molecular medicine and targeted delivery of therapeutic agents. More specifically, the present invention relates to the identification of novel peptide sequences that incorporate the amino acids Leu-Pro-Arg (LPR), and particu...
02/02/2012
20120027797Preservation of Bioactive Materials by Freeze Dried Foam
This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes....
02/02/2012
20120027788SIMIAN ADENOVIRUS NUCLEIC ACID- AND AMINO ACID-SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREOF
The present invention relates to novel adenovirus strains with an improved sero-prevalence. In one aspect, the present invention relates to isolated polypeptides of adenoviral capsid proteins such as hexon, penton and fiber protein and fragments thereof and polynucleoti...
02/02/2012
20120027789ANTIGENIC PEPTIDE OF HSV-2 AND METHODS FOR USING SAME
The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are epitopes confirmed to be recognized by T-cells derived from herpetic lesions. T-cells having specificity for antigens of the invention have demons...
02/02/2012
20120028335ANTI-VIRAL AZIDE-CONTAINING COMPOUNDS
Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of la...
02/02/2012
20120027790IMMUNOLOGICAL HERPES SIMPLEX VIRUS ANTIGENS AND METHODS FOR USE THEREOF
The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are antigens and/or their constituent epitopes confirmed to be recognized by T-cells derived from herpetic lesions or from uterine cervix. T-cells hav...
02/02/2012
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