Class 435/195 - Hydrolase (3. )

Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter wherein the enzyme catalyzes the followingreaction;
No. of applications: 267
Last issue date: 02/23/2012

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Application No.	Application Title	Issue Date
20120045813	GENE ENCODING A PROTEIN HAVING AN ABILITY TO ENHANCE A SELENATE REDUCTION ACTIVITY According to the present invention, a protein having an ability to enhance a selenate reduction activity, a gene encoding it, and a method for selenate reduction using them are provided...	02/23/2012
20120039861	IDENTIFICATION OF EXTRACELLULAR FORM OF PTEN THAT CAN BE USED TO TREAT TUMORS An isolated human phosphatase and tensin homolog long polypeptide (PTEN-long) comprising SEQ ID NO:1, fragments and analogues thereof, nucleic acids encoding such and compositions comprising such are provided. Methods to inhibit angiogenesis in a solid tumor, treat a so...	02/16/2012
20120021486	ENZYME-BASED NANOSCALE DECONTAMINATING COMPOSITES The invention relates to decontaminating composites, and methods, compositions, and kits comprising the same. In some aspects, the invention relates to a decontaminating composite, comprising a perhydrolase associated with a carbon nanotube, that is useful for producing...	01/26/2012
20120003713	Polymerase Enhancing Factor (PEF) Extracts PEF Protein Complexes Isolated PEF Proteins and Methods for Purifying and Identifying The invention provides novel extracts, proteins, and complexes that improve the polymerization activity of nucleic acid polymerases. Included within the aspects of the invention are methods for identifying compositions with a polymerase enhancing activity, methods for p...	01/05/2012
20110318803	PROCESS FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION FOR PRODUCTION OF ETHANOL Methods are disclosed for the production of high concentrations of ethanol from biomass using Zymomonas as the ethanologen. Zymomonas is grown under conditions of low impeller agitation with high concentration of insoluble solids in a saccharification-ferm...	12/29/2011
20110314564	ENZYMES AND METHODS FOR HYDROLYSING PHENYLUREAS, CARBAMATES AND ORGANOPHOSPHATES The present invention relates to enzymes which are able to hydrolyse phenylureas, carbamates, and/or organophosphates, as well as polynucleotides encoding these enzymes. The present invention also relates to methods of hydrolysing phenylureas, carbamates, and/or organop...	12/22/2011
20110306139	Mutant Cells Suitable For Recombinant Polypeptide Production A mutated bacterial cell producing at least one heterologous polypeptide of interest, wherein said cell has a reduced expression-level of a polypeptide comprising an amino acid sequence at least 70% identical to the sequence shown in SEQ ID NO: 2, when compared with an ...	12/15/2011
20110305667	USE OF A DEAD-BOX RNA HELICASE FOR INDUCING CYTOKINE PRODUCTION The invention relates to the use of a DEAD-box RNA helicase from a yeast, a mammal, Leishmania infantum, or fragments thereof for inducing the production of cytokines by a peripheral blood mononuclear cell (PBMC) of a mammal, and to the applications thereof....	12/15/2011
20110300575	CELL-FREE SYSTEM FOR SYNTHESIS OF PROTEINS DERIVED FROM CULTURED MAMMALIAN CELLS Prepared is an extract composition having an improved protein synthetic activity in a cell-free protein synthesis system using a mammalian cultured cell extract. An eukaryotic translation initiation factor and/or translational regulator are added to a cell-free protein ...	12/08/2011
20110294697	SYSTEM FOR DETECTNG PROTEASE Disclosed is a system for detecting a protease inside a cell. In one embodiment, the system includes a chimeric protein that comprises as covalently linked components: 1) at least one optionally masked signal protein; 2) at least one protease-specific cleavage site; and...	12/01/2011
20110287511	Novel Trichoderma Genes Described herein are novel gene sequences isolated from Trichoderma reesei. Two genes encoding proteins comprising a cellulose binding domain, one encoding an arabionfuranosidase and one encoding an acetylxylanesterase are described. The sequences, CIP1 and CIP2,...	11/24/2011
20110275135	Genetic elements, proteins, and associated methods including application of additional genetic information to gram (+) thermoacidophiles Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering recombination inside or outside of a cell using isolated and/or purif...	11/10/2011
20110250181	HUMAN LYSOSOMAL PROTEINS FROM PLANT CELL CULTURE A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or by-passing the Golgi. The invention further relates to vectors and methods...	10/13/2011
20110252509	Method for Producing a Transgenic Cell with Increased Gamma-Aminobutyric Acid (Gaba) Content This invention relates generally to a method for producing a transgenic cell with increased gamma-aminobutyric acid (GABA) content as compared to a corresponding non-transformed wild type cell....	10/13/2011
20110247098	Plants Having Enhanced Abiotic Stress Tolerance and/or Enhanced Yield-Related Traits and a Method for Making the Same The present invention relates generally to the field of molecular biology and concerns a method for enhancing abiotic stress tolerance in plants by modulating expression in a plant of a nucleic acid encoding a cytochrome c oxidase (COX) VIIa subunit polypeptide (COX VII...	10/06/2011
20110243915	ANTIMICROBIAL AGENTS The present invention relates to endolysin variants comprising an endolysin to which a peptide stretch with membrane or LPS disrupting activity is fused. Moreover, the present invention relates to nucleic acid molecules encoding said modified endolysin variant, vectors ...	10/06/2011
20110236397	LIMITED PROTEOLYSIS OF CD2AP AND PROGRESSION OF RENAL DISEASE Compositions which specifically block cathepsin L function in podocytes, compositions which protect cytoskeletal adaptor protein (CD2AP) for degradation, compositions which modulate expression or function of cytoskeletal adaptor protein (CD2AP), protect against renal di...	09/29/2011
20110236953	EMBRYONIC CEREBROSPINAL FLUID (e-CSF), PROTEINS FROM e-CSF, AND RELATED METHODS AND COMPOSITIONS We have performed a proteomic analysis of embryonic cerebrospinal fluid (e-CSF) in human and rats. Based on this discovery, the invention features methods and compositions for cell culture including components of e-CSF or fragments thereof. Also provided are methods for...	09/29/2011
20110229450	ENZYMES AND METHODS FOR DEGRADING S-TRIAZINES AND DIAZINES The present invention relates to polypeptides for degrading s-triazines such as atrazine, as well as diazines. Also provided are polynucleotides encoding these polypeptides. The present invention also relates to the use of these polynucleotides and polypeptides in the b...	09/22/2011
20110223616	HuR-Associated Biomarkers The present invention relates to methods of identifying gene targets, including methods of using ribonucleoprotein (RNP) immunoprecipitation-microarrays to identify cancer gene targets, such as subsets of RNP-associated mRNAs in breast cancer cell lines. Also presented,...	09/15/2011
20110217740	METHODS, MICROORGANISMS, AND COMPOSITIONS FOR PLANT BIOMASS PROCESSING Disclosed herein are methods of degrading plant biomass, and microorganisms and polypeptides used in such methods, hi certain embodiments, the methods include growing Anaerocellum thermophilum on a substrate that comprises plant biomass under conditions effective...	09/08/2011
20110217745	Enhancement of Enzymatic Hydrolysis of Pre-treated Biomass by Added Chitosan A process for producing a fermentation product from a lignocellulose-containing material includes pre-treating the lignocellulose-containing material; introducing chitosan or a chitosan-like polymer to the pre-treated lignocellulose-containing material; exposing the pre...	09/08/2011
20110212895	Treatment of Cognitive and Learning Impairment Constitutive activators of Rho GTPases are useful in treating learning an cognitive disorders....	09/01/2011
20110212898	CHIMERIC PEPTIDES FOR THE REGULATION OF GTPASES Chimeric peptides or fusion proteins are disclosed that include a RhoGAP activity domain and at least one specificity domain that targets a specific Rho protein. The fusion proteins can be used to inhibit any GTPase activity within a cell. The fusion proteins are partic...	09/01/2011
20110207182	Novel thermophilic cellobiohydrolase The present invention provides for a composition comprising a polypeptide comprising a first amino acid sequence having at least 70% identity with the amino acid sequence of Csac GH5 wherein said first amino acid sequence has a thermostable or thermophilic cellobiohydro...	08/25/2011
20110207775	AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT VESICLE-FUSING ATPASE ACTIVITY The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect vesicle-fusing ATPase; a method for assaying pesticidal activity of a test substance, which comprises measurin...	08/25/2011
20110201069	Method for Producing Oligomer and/or Monomer by Degrading Biodegradable Resin An object of the present invention is to provide a method for efficiently producing an oligomer or a monomer by degrading a biodegradable resin using an enzyme, so that the oligomer or the monomer can be recovered. The present invention pro...	08/18/2011
20110196180	METHODS AND COMPOSITIONS FOR PRODUCING OLEFINS Compositions and methods for producing olefins are described herein. The olefins can be used to produced biofuels....	08/11/2011
20110189711	PAAD DOMAIN-CONTAINING POLYPEPTIDES, ENCODING NUCLEIC ACIDS, AND METHODS OF USE The invention provides isolated nucleic acid molecules encoding PAAD-domain containing polypeptides and functional fragments thereof, including fragments containing PAAD domains, NACHT domains and ARED domains, encoded polypeptides, and antibodies. Also provided are met...	08/04/2011
20110191902	Methods and Compositions for Increasing Storage-Life of Fruit The invention provides methods and compositions for producing plants with fruit having increased post-harvest storage life, the method comprising reducing the expression or activity in the plant, of a polypeptide with the amino acid sequence of SEQ ID NO: 1, or a varian...	08/04/2011
20110177154	Tubular nanostructure targeted to cell membrane Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. ...	07/21/2011
20110171244	RECOMBINANT PROTEIN CARRYING HUMAN PAPILLOMAVIRUS EPITOPES INSERTED IN AN ADENYLATE CYCLASE PROTEIN OR FRAGMENT THEREOF THERAPEUTIC USES THEREOF The invention relates to a recombinant protein comprising one or several polypeptides bearing one or several epitopes of one or several HPV antigens, said polypeptides being inserted in the same or different permissive sites of an adenylate cyclase (CyaA) protein or of ...	07/14/2011
20110154519	HAFNIA PHYTASE The present invention relates to isolated polypeptides having phytase activity and isolated polynucleotides encoding the polypeptides. The polypeptides are related to a phytase derived from Hafnia alvei, the amino acid sequence of which is shown in the appended sequence...	06/23/2011
20110136907	PERHYDROLASE PROVIDING IMPROVED PERACID STABILITY An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-pro...	06/09/2011
20110111442	Intein-modified enzymes, their production and industrial applications A method of predicting an intein insertion site in a protein that will lead to a switching phenotype is provided. The method includes identifying a plurality of C/T/S sites within the protein; selecting from the plurality of C/T/S/ sites those that are ranked 0.75 or hi...	05/12/2011
20110104108	METHODS OF TREATING CANCER AND OTHER CONDITIONS OR DISEASE STATES USING LFMAU AND LDT The present invention relates to the use of the compound according to formula (I), below for the treatment of tumors, cancer and hyperproliferative diseases, among other conditions or disease states: Where X is H or F; R¹and R²are independently H...	05/05/2011
20110104682	RNA DETECTION ASSAYS The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic ...	05/05/2011
20110091889	CENTROSOME-ASSAY The present invention provides a centrosome assay for the identification of preferably, Eg5 inhibitors....	04/21/2011
20110092397	Thermophilic Mannanohydrolase and Fracturing Fluids Containing the Same A thermophilic mannanohydrolase enzyme may be used as an enzyme breaker for fracturing fluids containing hydratable polymers of guar and underivatized guar. The enzyme is effective in downhole temperatures exceeding 160° F....	04/21/2011
20110059869	Method for Increasing Enzymatic Reactivity An object of the invention is to provide a method for increasing enzymatic reactivity to a target substance immobilized on a support; and a method for reducing or suppressing an inhibitory effect of a support on enzymatic reaction. The above object is achieved by a meth...	03/10/2011

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Class 435/195 - Hydrolase (3. )