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| Application No. | Application Title | Issue Date |
| 20120129788 | PHOSPHODIESTERASE 4D7 AS MARKER FOR MALIGNANT, HORMONE-SENSITIVE PROSTATE CANCER The present invention relates to phosphodiesterase 4D7 (PDE4D7) for use as a marker for malignant, hormone-sensitive prostate cancer, wherein the expression of the marker is increased when comparing the expression in malignant, hormone-sensitive prostate cancer tissue, ... | 05/24/2012 |
| 20120108493 | Polypeptide Fragments Comprising Endonuclease Activity and Their Use The present invention relates to polypeptide fragments comprising an amino-terminal fragment of the PA subunit of a viral RNA-dependent RNA polymerase or variants thereof possessing endonuclease activity, wherein said PA subunit is from a virus belonging to the Orthomyx... | 05/03/2012 |
| 20120070443 | PDE1 AS A TARGET THERAPEUTIC IN HEART DISEASE Disclosed are compositions and methods related to inhibition of PDE1.... | 03/22/2012 |
| 20120034614 | EARLY DETECTION OF PATHOGENS IN BLOOD The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent i... | 02/09/2012 |
| 20120034637 | DETECTION OF TRICHOMONAS AND CANDIDA The invention relates to a method and a kit for the detection of Trichomonas infection by detecting N-acetyl-β-D-hexosaminidase activity. The invention also relates to a method and a kit for selective detection of presence of Trichomonas or Candida | 02/09/2012 |
| 20120009613 | PHARMACEUTICAL COMPOSITION FOR MODULATING THE ACTIVITY OF A NOVEL TRIGLYCERIDE HYDROLASE Use of an inhibitor or activator of the triglyceride hydrolyse activity of a protein comprising a polypeptide strand encoded by the DNA sequence according to SEQ No. 1 for the preparation of a pharmaceutical composition for the treatment of medical disorders where it is... | 01/12/2012 |
| 20120003677 | IDENTIFICATION OF TISSUE FOR DEBRIDEMENT Provided are methods of determining whether a cell in a tissue site is viable or nonviable. Also provided are methods of debriding tissue from a tissue site. Further provided are kits comprising a compound that distinguishes between viable and nonviable cells and instru... | 01/05/2012 |
| 20120003243 | YEAST ECTOPICALLY EXPRESSING ABNORMALLY PROCESSED PROTEINS AND USES THEREFOR Disclosed are yeast ectopically expressing abnormally processed proteins and methods of screening to identify compounds that modulate the function of such abnormally processed proteins in yeast. Compounds identified by such screens can be used to treat or prevent diseas... | 01/05/2012 |
| 20120003661 | METHODS AND DEVICES FOR THE SELECTIVE DETECTION OF MICROORGANISMS Methods and devices are provided for the rapid and specific detection of target microorganisms, cells, and the like. In one embodiment, the methods involve contacting a target microorganism (e.g., in a sample) with a permeabilization reagent that selectively permeabiliz... | 01/05/2012 |
| 20110321197 | Plants with Increased Yield (NUE) A method for producing a plant with increased yield as compared to a corresponding wild type plant whereby the method comprises at least the following step: increasing or generating in a plant or a part thereof one or more activities selected from the group consisting o... | 12/29/2011 |
| 20110311505 | Photosensitive Aminoacid-Monomer Linkage and Bioconjugation Applications in Life Sciences and Biotechnology This invention is related to preparation of photosensitive ruthenium based aminoacid monomers and oligomers, aminoacid monomer-protein cross-linking using photo sensitat ion and conjugation on micro and nano-structures by ruthenium-chelate based monomers. Its vast range... | 12/22/2011 |
| 20110312008 | Enzymatic Assay for the Quantitative Determination of Phospholipase A1 or A2 Activity in a Sample The invention relates to a new method for measuring phospholipase A1 or A2 activity in a sample, using a solid phase coated with a fluorochrome-labelled phospholipase A1 or A2 substrate, wherein the molecular coverage is in the range from 8 to 30 fluorochrome-labelled p... | 12/22/2011 |
| 20110300282 | PRODUCTION OF MONATIN ENANTIOMERS Methods for preferentially hydrolyzing one stereoisomer of an isoxazoline diester over another, as well as an enzyme for facilitating the preferential hydrolysis are provided. Also provided are methods for providing mixtures of (RR) and (RS) monatin as well as (SS) and ... | 12/08/2011 |
| 20110296554 | SPECIFIC GENETIC MODIFICATION OF THE ACTIVITY OF TREHALOSE-6-PHOSPHATE SYNTHASE AND EXPRESSION IN A HOMOLOGOUS OR HETEROLOGOUS ENVIRONMENT A method for the preparation of a eukaryotic organism, for example selected from plants, animals and fungi, showing constitutive, inducible and/or organ specific expression of a specifically modified TPS gene, which comprises the steps of providing a TPS gene; designing... | 12/01/2011 |
| 20110294134 | METHODS AND KITS FOR DETERMINING A RISK TO DEVELOP CANCER, FOR EVALUATING AN EFFECTIVENESS AND DOSAGE OF CANCER THERAPY AND FOR CORRELATING BETWEEN AN ACTIVITY OF A DNA REPAIR ENZYME AND A CANCER Methods and kits for (i) determining a risk of a subject to develop cancer; (ii) evaluating an effectiveness and dosage of cancer therapy administered to a cancer patient; and (iii) determining a presence of correlation or non-correlation between an activity of at least... | 12/01/2011 |
| 20110277046 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity... | 11/10/2011 |
| 20110270054 | ASSAY FOR POSITIONING A FEEDING TUBE AND METHOD THEREOF The present invention discloses a bedside or point of care assay for properly positioning a feeding tube in the stomach of a patient based on detecting the presence of a hydrolytic enzyme found in the stomach by an ester substrate which can be impregnated on a pH strip.... | 11/03/2011 |
| 20110262450 | MODULATORS OF MONOGLYCERIDE LIPASE IN THE TREATMENT OF ACNE, OF SEBORRHOEIC DERMATITIS OR OF HYPERSEBORRHOEA An in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea, includes determining the ability of a compound to modulate the expressio... | 10/27/2011 |
| 20110256566 | Determination of biological material ingredients The invention relates to a method for analysing ingredients, in particular lipids and/or vitamins and biological materials with a concentration of the biological material ingredients, to uses of relevant organic solvents or organic solvent mixtures, and to a spectrophot... | 10/20/2011 |
| 20110251094 | BIOMARKERS FOR HYPERTENSIVE DISORDERS OF PREGNANCY The application discloses new biomarkers for hypertensive disorders of pregnancy and particularly preeclampsia; methods for the diagnosis, prediction, prognosis and/or monitoring said disorders based on measuring said biomarkers; and kits and devices for measuring said ... | 10/13/2011 |
| 20110243854 | Methods and systems for identifying modulators of longevity Methods of treating disorders such as neurofibromatosis-1 are provided, including methods in which catalytic antioxidants such as metalloporphyrins are administered. Methods of regulating longevity, and methods and systems for screening for modulators of aging or longev... | 10/06/2011 |
| 20110236913 | COMPOSTION AND KIT FOR DIAGNOSING IMMUNOGLOBULIN A NEPHROPATHY AND TGBM NEPHROPATHY Disclosed is the development of a protein used as a biomarker for diagnosing IgA nephropathy and TGBM (thin-glomerular-basement-membrane) using urine through a target proteomics method. The disclosed development relates to a diagnosis biomarker protein and a kit for dia... | 09/29/2011 |
| 20110229919 | COMBINATION OF SPLA2 ACTIVITY AND OXPL/APOB CARDIOVASCULAR RISK FACTORS FOR THE DIAGNOSIS/PROGNOSIS OF A CARDIOVASCULAR DISEASE/EVENT. A method of identifying a subject having or at risk of having or developing a cardiovascular disease and/or a cardiovascular event, includes:
| |
| 20110229917 | MULTIPLEX LIQUID TISSUE™ METHOD FOR INCREASED PROTEOMIC COVERAGE FROM HISTOPATHOLOGICALLY PROCESSED BIOLOGICAL SAMPLES, TISSUES AND CELLS The invention provides methods for multiplex analysis of biological samples of formalin-fixed tissue samples. The invention provides for a method to achieve a multiplexed, multi-staged plurality of Liquid Tissue preparations simultaneously from a single histopathologica... | 09/22/2011 |
| 20110230372 | GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUTCOME PREDICTION IN PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high risk B-precursor acute lymphoblastic leukemia (B-ALL) and associated methods ... | 09/22/2011 |
| 20110212477 | LIPOPROTEIN-ASSOCIATED MARKERS FOR CARDIOVASCULAR DISEASE The invention provides methods of screening a mammalian subject to determine if the subject is at risk to develop, or is suffering from, cardiovascular disease. The methods comprise detecting an amount of at least one biomarker in a biological sample, or HDL subfraction... | 09/01/2011 |
| 20110214195 | Methods For Treating Clinical Conditions Associated With Lipoprotein Lipase Activity The present invention provides methods for treating a clinical condition associated with lipoprotein lipase activity in the brain of a subject.... | 09/01/2011 |
| 20110212047 | Polymer Therapy for the Treatment of Chronic Microvascular Diseases Methods are provided for the treatment of chronic microvascular diseases characterized by inflammation, such as age-related macular degeneration, by administering a polyoxyethylene/polyoxypropylene copolymer. Although a single dose can be effective, multiple treatments ... | 09/01/2011 |
| 20110207159 | SCREENING METHOD FOR EFFICIENTLY OBTAINING USEFUL MICROBIAL STRAINS FROM MICROBIAL SAMPLE OBTAINED FROM NATURAL ENVIRONMENT AND REAGENT AND SCREENING KIT TO BE USED THEREFOR A screening method for efficiently obtaining useful microbial strains from a sample comprises a first step of inoculating a culture medium with the sample potentially containing multiple microbial cells to culture the sample in the presence of a cell enlarger; a second ... | 08/25/2011 |
| 20110207158 | Method for the non-invasive detection of microorganisms in a closed container The present invention relates to a method for detecting a contamination with a microorganism in a closed container, in which an extracellular enzyme of the microorganism is detected. The method can very suitably be carried out by providing a substrate for this enzyme to... | 08/25/2011 |
| 20110207160 | METHOD FOR MEASURING LOW DENSITY LIPOPROTEIN CHOLESTEROL It is an object of the present invention to provide a method capable of measuring low density lipoprotein cholesterol (LDL) in a body fluid with high selectivity. The present invention provides a method for measuring low density lipoprotein cholesterol (LDL-C) in a body... | 08/25/2011 |
| 20110201947 | OXIDIZED PARAOXONASE 1 AND PARAOXONASE 1/HDL PARTICLE NUMBER RATIO AS RISK MARKERS FOR CARDIOVASCULAR DISEASE The present invention provides methods and markers for characterizing a subject's, particularly a human subject risk of having cardiovascular disease. The present invention also provides methods of characterizing a subject's risk of developing cardiovascular disease. In... | 08/18/2011 |
| 20110195915 | Method of inhibiting prostate cancer cell proliferation The present invention relates to a method of inhibiting or reducing the proliferation of prostate cancer cells, such as androgen independent prostate cancer (AIPC) cells, the method comprising administering to the cells a PLA2 inhibitor. In one embodiment the... | 08/11/2011 |
| 20110195427 | SYSTEMS AND METHODS FOR DETECTING PREGNANCY Systems and methods for detecting pregnancy. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for pregnancy in a bo... | 08/11/2011 |
| 20110195849 | METHODS AND COMPOSITIONS FOR IDENTIFYING INHIBITORS OF MUTS-alpha OR MUTS-beta INTERACTION WITH MUTL-alpha Disclosed are methods and kits for screening potential inhibitors of MutSβ by screening agents for the ability to selectively inhibit interaction between MutSβ and MutLα. Also disclosed are kits for performing the methods of the invention.... | 08/11/2011 |
| 20110195440 | SYSTEMS AND METHODS FOR IDENTIFYING ALLERGIES Systems and methods for identifying allergies. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a non-food alle... | 08/11/2011 |
| 20110195422 | METHODS FOR DETERMINING THE EFFICIENCY OF A THERAPEUTIC Methods for determining the efficiency of a therapeutic. In at least one embodiment of a method of determining the efficacy of a therapeutic compound, the method comprises the steps of treating a subject having a disease state with an effective amount of therapeutic com... | 08/11/2011 |
| 20110189199 | METHODS FOR P2RY5 MEDIATED REGULATION OF HAIR GROWTH AND MUTANTS THEREOF The invention provides for a method for screening compounds that bind to and modulate the hair-specific G-protein coupled receptor, P2RY5. The invention further provides for methods for controlling hair growth by administering a P2RY5 modulating compound to a subject.... | 08/04/2011 |
| 20110183318 | METHOD FOR SCREENING OF SUBSTANCE EFFECTIVE ON DISEASE USING GPR120 AND PHOSPHOLIPASE The present invention provides a screening method for determining whether a substance of interest is a substance which alters GPR120 mediated cell stimulating activities, comprising using a substance of interest, a biomembrane containing GPR120, or cells containing said... | 07/28/2011 |
| 20110175982 | METHOD OF FLUORESCENT NANOSCOPY An analysis of an object dyed with fluorescent coloring agents carried out with the aid of a fluorescent microscope which is modified for improved resolving power and called a nanoscope. The method is carried out with a microscope having an optical system for visualizin... | 07/21/2011 |
