...that the x-ray was discovered purely by accident? When German physicist Wilhelm Konrad von Roentgen was experimenting with cathode rays in 1895, he put an activated Crookes tube in a book and went out to lunch. When he returned, he discovered that a key that had also been placed in the book showed up as an image on the developed film!
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| Application No. | Application Title | Issue Date |
| 20120129693 | SEED HAVING INOCULATED WITH BACTERIAL BILFILM Disclosed are: a seed having resistance to diseases; and a method for inoculating a microorganism into a seed for the purpose of controlling diseases. As a result of intensive studies, it is found that diseases of a crop can be controlled by inoculating a biofilm of a <... | 05/24/2012 |
| 20120079764 | METHODS AND COMPOSITIONS USING FUNGAL LACCASES TO REDUCE TURF THATCH The present disclosure describes methods and compositions for reducing turf thatch and/or preventing turf thatch buildup.... | 04/05/2012 |
| 20120041076 | GEL FORMING SOLUTION AND METHOD FOR PRODUCING GEL A method for producing a gel includes a liquid droplet ejection step in which a first liquid is ejected in the form of a droplet to a second liquid to allow the first liquid and the second liquid to react with each other, thereby producing a gel. The first liquid is a g... | 02/16/2012 |
| 20120040011 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The re... | 02/16/2012 |
| 20120034670 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND PROCESS FOR PRODUCING SAME Disclosed is an organic-inorganic composite material obtained by chemically modifying a microorganism-derived ceramic material with an organic group, and a process for producing the organic-inorganic composite material. The process is characterized by reacting a microor... | 02/09/2012 |
| 20120028287 | Crystal Structure of Aldehyde Dehydrogenase and Methods of Use Thereof The present disclosure provides a crystal structure of aldehyde dehydrogenase (ALDH) with a modulator of ALDH bound thereto. The present disclosure provides a computer readable medium comprising atomic coordinates for an ALDH polypeptide and a modulator bound to a site ... | 02/02/2012 |
| 20120027837 | MULTILAYER COATING COMPOSITIONS, COATED SUBSTRATES AND METHODS THEREOF The present invention provides, among other things, multilayer film coating compositions, coated substrates and methods thereof In some embodiments, a structure, comprising a substrate and a multilayer film on the substrate, wherein the multilayer film comprises a first... | 02/02/2012 |
| 20120018377 | DIALYSATE REGENERATION SYSTEM FOR PORTABLE HUMAN DIALYSIS A dialysate regeneration chamber is provided. In one embodiment, the dialysate regeneration chamber may include a toxin trap configured to selectively trap toxins and repel select cations.... | 01/26/2012 |
| 20120014957 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided.... | 01/19/2012 |
| 20120009645 | CULTURE OF PLURIPOTENT AND MULTIPOTENT CELLS ON MICROCARRIERS A method is disclosed for culturing pluripotent or multipotent cells in vitro, the method comprising attaching pluripotent or multipotent cells to a plurality of microcarriers to form microcarrier-cell complexes, and culturing the microcarrier-cell complexes in suspensi... | 01/12/2012 |
| 20120009173 | CYTOTOXIC RIBONUCLEASE VARIANTS This invention relates to cytotoxic variants of human ribonuclease 1 (RNase 1) identified through analysis of the interaction between RNase 1 and the human ribonuclease inhibitor (hRI) as defined by the three dimensional (3-D) atomic structure of the RNase1 hRI complex.... | 01/12/2012 |
| 20120003711 | DEVICE FOR CAPTURING CIRCULATING CELLS The present invention provides devices and methods for capturing rare cells. The devices and methods described herein can be used to facilitate the diagnosis and monitoring of metastatic cancers.... | 01/05/2012 |
| 20110306110 | METHOD FOR THREE-DIMENSIONAL HIERARCHICAL CELL CO-CULTURE A method for preparing a biomaterial comprising a gel layer which forms a core region, and cells (cover cells) which cover around the gel layer, said method comprising the steps of: (a) bringing a biocompatible oil or a vegetable oil or a m... | 12/15/2011 |
| 20110294187 | CAPTURING PARTICLES Methods and systems capturing particles suspended in a fluid flowed through a micro-channel, can include flowing the fluid including the particles to be captured through a micro-channel and past a groove defined in a surface of a wall of the micro-channel such that flow... | 12/01/2011 |
| 20110294159 | Biocompatible Article for the Treatment of Water and Production of Energy A biocompatible article including (a) a biocompatible hydrogel; (b) an adhesive coating on at least a portion of the hydrogel; and (c) one or more organisms adhered to at least a portion of the adhesive coating is disclosed.... | 12/01/2011 |
| 20110294186 | DEVICES AND METHODS FOR ENRICHMENT AND ALTERATION OF CIRCULATING TUMOR CELLS AND OTHER PARTICLES The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.... | 12/01/2011 |
| 20110277046 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity... | 11/10/2011 |
| 20110275103 | EMISSION RATIOMETRIC REPORTERS OF MEMBRANE PDK1 ACTIVATION Phosphoinositide-dependent kinase 1 (PDK1) activity reporters can be used in high throughput assays for drug screening.... | 11/10/2011 |
| 20110269207 | CELL AND BIOFACTOR PRINTABLE BIOPAPERS Disclosed herein is a structure having: a porous polymeric film permeated by a first extracellular matrix material; and a topcoat layer comprising a second extracellular matrix gel disposed on the film. Also disclosed herein is a method of: providing a porous polymeric ... | 11/03/2011 |
| 20110262348 | Selective targeting of intratumoral cells The present invention relates to the field of tumor growth and biology. The invention relates to activities and characteristics of tumor-associated macrophages, and uses of such for the diagnosis and treatment of cancer and tumor growth.... | 10/27/2011 |
| 20110256552 | METHOD FOR PREPARING A SUBSTRATE FOR IMMOBILIZING A CELL, SAID SUBSTRATE AND USES THEREOF The present invention relates to a method of preparation of a solid substrate capable of immobilizing at least one cell and/or at least one part of a cell, said method comprising a step consisting of fixing, to said solid substrate, a fusogenic compound capable of being... | 10/20/2011 |
| 20110236884 | MICROBUBBLES FOR AFFINITY SEPARATION The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule. Particularly, the invention provides protein microbubbles coated with an affinity mol... | 09/29/2011 |
| 20110229579 | Support Having Nanostructured Titanium Dioxide Film And Uses Thereof The present invention relates to supports for bioassays and the use thereof in cell culturing and in cell-based methods and assays. More precisely, the invention provides solid materials coated with films of nanostructured titanium dioxide suitable for the immobilisatio... | 09/22/2011 |
| 20110217750 | Dendrimers and Dendrimer Applications An activatable functionalised Nth generation dendrimer having: a core comprising a first monomer having at least two carboxylic acid functional groups; and N successive generations, where N=0 to 10, wherein each generation comprises: a second monomer having a... | 09/08/2011 |
| 20110191875 | COMPOSITIONS AND METHODS FOR MAKING ANDROSTENEDIONES The invention provides compositions and methods for producing androstenedione (4-androstenedione), of improved purity and for modulating its production, for example by deletion or inactivation of ksdA, cxgA, cxgB, cxgC, or cxgD. The invention also provides methods and c... | 08/04/2011 |
| 20110159543 | SCALABLE PROCESS FOR CULTURING PER.C6 CELLS AND PRODUCING PRODUCTS THEREFROM The invention provides methods for culturing adherent PER.C6 cells and producing products therefrom.... | 06/30/2011 |
| 20110142804 | NANOFIBER SCAFFOLD The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber dia... | 06/16/2011 |
| 20110129893 | MONITORING TARGET ENDOGENOUS SPECIES An electrode comprising: a conducting substrate for detecting an electroactive agent; a catalytic agent held on the substrate for converting a non-electroactive agent to an electroactive agent by a catalytic process which consumes oxygen; and an oxygen reservoir, for re... | 06/02/2011 |
| 20110126457 | METHOD FOR PRODUCING CARRIER ON WHICH MICROORGANISMS CAPABLE OF CONDUCTING MULTIPLE PARALLEL MINERALIZATION ARE IMMOBILIZED, COLUMN REACTOR AND SOLID MEDIUM FOR CULTIVATING PLANTS An object of the present invention is to provide a method of efficiently producing nitrate nitrogen as inorganic nutrients from an organic material without performing any operation using constant electrical power such as aeration. Another object of the present invention... | 06/02/2011 |
| 20110124079 | Sorption reinforced catalytic coating system and method for the degradation of threat agents Sorption reinforced catalytic coating system for the degradation of threat agents including a synzyme coating about a material configured for the degradation of the threat agents, the synzyme coating including bucket-shaped molecules configured for the sorption of the t... | 05/26/2011 |
| 20110111008 | Use of PEDF in an Encapsulated Cell-Based Delivery System The invention relates to a device for delivery of pigment epithelium derived factor (PEDF) to the eye utilizing encapsulated PEDF-secreting cells and related methods for the treatment and prevention of ophthalmic diseases and disorders.... | 05/12/2011 |
| 20110091956 | BIOMOLECULE-IMMOBILIZED CARRIER AND METHOD FOR IMMOBILIZING BIOMOLECULE ON CARRIER Provided are a biomolecule-immobilized carrier obtained by immobilizing a biomolecule having a membrane-binding peptide containing a C terminal polypeptide of fucosyltransferase derived from Helicobacter pylori or a membrane-binding molecule having the membrane-b... | 04/21/2011 |
| 20110091955 | METHODS AND SYSTEMS FOR TREATING INDUSTRIAL WASTE GASES Systems and methods for lowering levels of carbon dioxide and other atmospheric pollutants are provided. Economically viable systems and methods capable of removing vast quantities of carbon dioxide and other atmospheric pollutants from gaseous waste streams and sequest... | 04/21/2011 |
| 20110081701 | SURGICAL COMPOSITIONS The present disclosure relates to methods of cell encapsulation using multi-component hydrogels. The hydrogels may include a natural component having nucleophilic functional groups as well as an electrophilic component. In embodiments, at least one of the components may... | 04/07/2011 |
| 20110076736 | FUEL CELL, METHOD FOR MANUFACTURING FUEL CELL, ELECTRONIC APPARATUS, ENZYME IMMOBILIZATION ELECTRODE, BIOSENSOR, BIOREACTOR, ENERGY CONVERSION ELEMENT, AND ENZYME REACTION-UTILIZING APPARATUS A fuel cell and a method for manufacturing the same are provided, wherein at least one type of enzyme and coenzyme are confined in a minute space, an enzyme reaction is effected while this space serves as a reaction field. Thereby, electrons can be taken out of the fuel... | 03/31/2011 |
| 20110071087 | POLYPEPTIDES HAVING MODULATORY EFFECTS ON CELLS The present invention relates to peptides and polypeptides having the sequence SAVTFAVCAL or variants thereof, capable of binding to Calcineurin and/or to NS5A-TP2 and to their use in therapy, as well as to nucleic acid sequences and vectors encoding these peptides and ... | 03/24/2011 |
| 20110052680 | ENCAPSULATION OF OXIDATIVELY UNSTABLE COMPOUNDS An encapsulated material containing an oxidation-sensitive core is covered by at least a dried phospholipid layer, and contains at least one phytosterol in the core, the phospholipid layer or in a further layer or layers. By using microencapsulation, oxidatively unstabl... | 03/03/2011 |
| 20110020519 | ENCAPSULATION OF OXIDATIVELY UNSTABLE COMPOUNDS An encapsulated material is formed by congealing droplets of a molten blend of oxidatively unstable material and phytosterol in a chilling gas stream to form prilled cores containing oxidatively unstable material and phytosterol, and encapsulating the prilled cores in o... | 01/27/2011 |
| 20110014125 | PROTEASE ASSAY The present invention provides a diagnostic reagent or assay for assessing the activity of a protease in vivo or in vitro and methods of detecting the presence of a cancerous or precancerous cell. The assays are comprised of two particles linked via an oligopeptide link... | 01/20/2011 |
| 20100317024 | DERIVATIVES, REAGENTS, AND IMMUNOASSAY FOR DETECTING LEVETIRACETAM Levetiracetam (LEV) derivatives, methods for synthesizing LEV derivatives, and immunodiagnostic assays for LEV. The synthesis methods described herein include chirally-selective, liquid-phase synthesis steps to produce selected LEV derivatives in high-yield. LEV derivat... | 12/16/2010 |