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A hand wearable body squeegee comprising a glove portion, a concave squeegee band, and a linear squeegee band.
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| Application No. | Application Title | Issue Date |
| 20120128651 | ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) BIOMARKERS The present invention concerns the use of biomarkers for acute lymphoblastic leukemia (ALL) to prognose or evaluate a patient with ALL who is Ph+. Methods and compositions are provided that concern these ALL biomarkers. In specific embodiments, methods for determining w... | 05/24/2012 |
| 20120128657 | SYNTHETIC MACROCYCLIC COMPOUNDS AND METHODS FOR TREATING CANCER Disclosed herein are macrocyclic compounds that are effective to inhibit cell migration. In one embodiment, the compounds have the structure: or any pharmaceutically acceptable salt or solvate thereof, wherein: m is 0 or 1; R1, R2 and R3 05/24/2012 | |
| 20120128635 | METHODS AND COMPOSITIONS FOR TREATING HEMOPHILIA B Disclosed herein are methods and compositions for insertion of Factor IX (FIX) sequences into the genome of a cell for treating hemophilia B.... | 05/24/2012 |
| 20120107323 | KINASE PROTEIN BINDING INHIBITORS The invention provides compounds capable of treating a subject suffering from or being susceptible to a cell proliferative disorder (especially, cancer), methods of identifying and using the compounds, pharmaceutical compositions and kits thereof.... | 05/03/2012 |
| 20120107299 | PHOSPHORYLATION-INHIBITING AGENT OR DEPHOSPHORYLATING AGENT FOR PTEN Provided is a preventive, progression inhibitor or remedy for a disease one of the causes of which is the activation of the P13K/AKT signaling pathway or vice versa. A phosphorylation-inhibiting and/or dephosphorylating agent, which has an effect of inhibiting the phosp... | 05/03/2012 |
| 20120107230 | Treatment of Hyperproliferative Diseases with Vinca Alkaloid N-Oxide Analogs The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination ... | 05/03/2012 |
| 20120082656 | COMPOSITION COMPRISING THE PURIFIED EXTRACT OF BEE VENOM FOR PREVENTING AND TREATING DEGENERATIVE BRAIN DISEASE The present invention relates to a composition comprising the purified extract of bee venom for preventing and treating degenerative brain diseases and the use thereby. The purified extract of bee venom shows potent inhibitory effect on microglial cell activation and ab... | 04/05/2012 |
| 20120082654 | Method For Preventing And Controlling Organisms That Infest Aqueous Systems Method for preventing and controlling organisms that infest aqueous systems in which one or more organic or inorganic compounds capable of releasing gas are present, comprising the step of dispersing on and/or in the aqueous mass a preparation comprising enzymes adapted... | 04/05/2012 |
| 20120070504 | PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF THE SYMPTOMS OF ADDICTION AND METHOD OF DIAGNOSING SAME A therapeutic agent for the treatment of the symptoms of addiction and the method for preparing the therapeutic agent is disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive/pancreatic enzymes. The therapeutic... | 03/22/2012 |
| 20120070404 | Increasing cancer patient survival time by administration of dithio-containing compounds The present invention discloses and claims compositions, methods of treatment, and kits which cause an increase in the time of survival in cancer patients, wherein the cancer: (i) overexpresses thioredoxin or glutaredoxin and/or (ii) exhibits evidence of thioredoxin- or... | 03/22/2012 |
| 20120070416 | Macrocyclic Proline Derived HCV Serine Protease Inhibitors The present invention discloses compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus... | 03/22/2012 |
| 20120052052 | CONTROL OF BIOFILM FORMATION The invention relates to control of biofilm development. Specifically, some embodiments of the present invention relate to control of bacterial biofilm formation through addition or breakdown of signal(s) that induce biofilm formation. More specifically, some embodiment... | 03/01/2012 |
| 20120045412 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS The present invention provides a compound of general Formula (I) having histone deacetylase (HDAC) inhibitory activity, a pharmaceutical composition comprising the compound, and a method useful to treat diseases using the compound. ... | 02/23/2012 |
| 20120039861 | IDENTIFICATION OF EXTRACELLULAR FORM OF PTEN THAT CAN BE USED TO TREAT TUMORS An isolated human phosphatase and tensin homolog long polypeptide (PTEN-long) comprising SEQ ID NO:1, fragments and analogues thereof, nucleic acids encoding such and compositions comprising such are provided. Methods to inhibit angiogenesis in a solid tumor, treat a so... | 02/16/2012 |
| 20120041357 | METHOD OF CONTROLLED DRUG RELEASE FROM A LIPOSOME CARRIER Disclosed are methods and compositions for the controlled release of a drug or agent from a liposome using light or radiation. Also disclosed are compositions comprising liposomes having a lipid layer, wherein the liposomes contain an agent, an enzyme capable of releasi... | 02/16/2012 |
| 20120036599 | NOVEL FUNGAL ENZYMES This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and me... | 02/09/2012 |
| 20120034204 | FERTILIZATION MODULATION COMPOUNDS AND PROCESS FOR IMPLEMENTING THEM This invention relates to fertilization modulation compounds and process for implementing them.... | 02/09/2012 |
| 20120030838 | NOVEL FUNGAL ENZYMES This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and me... | 02/02/2012 |
| 20120027848 | Enzyme Delivery Systems and Methods of Preparation and Use This invention relates to coated digestive enzyme preparations and enzyme delivery systems and pharmaceutical compositions comprising the preparations. This invention further relates to methods of preparation and use of the systems, pharmaceutical compositions and prepa... | 02/02/2012 |
| 20120021036 | COMPOSITE NANOSTRUCTURES AND METHODS FOR MAKING AND USING THEM The invention provides nanostructures or products of manufacture for use as ex vivo or in vivo composition (e.g., a drug, or a therapeutic, diagnostic or imaging reagent) delivery vehicles. In one aspect, the invention provides nanoparticles comprising several compartme... | 01/26/2012 |
| 20120020878 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS The present invention comprises a method for delivering pharmaceutical and/or imaging agents within and/or through the dermal, mucosal and other cellular membranes, and across the blood-brain barrier, utilizing a fusogenic protein. The fusogenic protein is associated wi... | 01/26/2012 |
| 20120014964 | ALPHA SYNUCLEIN TOXICITY Present inventions demonstrates that alpha synuclein toxicity such as α-synuclein mediated cell death, alpha synuclein induced reactive oxygen species (ROS) in a cell requires the proapoptotic endonuclease G and that the deletion of the endonuclease G or suppressing of... | 01/19/2012 |
| 20120009172 | INTRAVENOUS AND ORAL DOSING OF A DIRECT-ACTING AND REVERSIBLE P2Y12 INHIBITOR The invention provides methods and compositions for rapid and reversible inhibition of platelet aggregation in human subjects in need thereof by administering compounds of the formula: alone or in combination... | 01/12/2012 |
| 20120009173 | CYTOTOXIC RIBONUCLEASE VARIANTS This invention relates to cytotoxic variants of human ribonuclease 1 (RNase 1) identified through analysis of the interaction between RNase 1 and the human ribonuclease inhibitor (hRI) as defined by the three dimensional (3-D) atomic structure of the RNase1 hRI complex.... | 01/12/2012 |
| 20120003202 | CNS DELIVERY OF THERAPEUTIC AGENTS The present invention provides an effective and less invasive approach for direct delivery of therapeutic agents to the central nervous system (CNS). In some embodiments, the present invention provides methods including a step of administering intrathecally to a subject... | 01/05/2012 |
| 20120003150 | THERAPEUTIC RIBONUCLEASES The present invention relates to the use of ribonucleases (RNases) in the treatment or prevention of disease.... | 01/05/2012 |
| 20110311445 | DIAGNOSIS AND TREATMENT OF MYELOID AND LYMPHOID CELL CANCERS Disclosed is a method of diagnosing and treating myeloproliferative or lymphoproliferative cell disorders, such as cancer, with chlorotoxin and/or derivatives, analogs or fragments thereof, which are effective to bind to an inhibit abnormal myeloid or lymphoid cell grow... | 12/22/2011 |
| 20110311478 | Combinatorial Methods For Treating Cellular Proliferative Disorders And Immune Deficiencies Using Salicinium The present invention provides novel immunotherapeutic compositions and methods useful for treating or preventing microbial infections, weakened immune systems, diseases in which cells have become obligately anerobic and cellular proliferative disorders including cancer... | 12/22/2011 |
| 20110311477 | Infusion Treatment Methods And Compositions Using Salicinium For Treating Cellular Proliferative Disorders And Immune Deficiencies The present invention provides novel immunotherapeutic compositions and methods useful for treating or preventing microbial infections, weakened immune systems, diseases in which cells have become obligately anaerobic and cellular proliferative disorders including cance... | 12/22/2011 |
| 20110311499 | Secretion System and Methods for its Use The present invention provides reagents and methods for inhibiting bacterial infection and abnormal cell growth, as well as for selection cloning of nucleic acid inserts.... | 12/22/2011 |
| 20110311601 | ANTIMICROBIAL MEDICAL DEVICES A medical device having a silane surface comprising an antimicrobial peptide exhibiting a complex tertiary structure, wherein the antimicrobial peptide is attached to the silane surface via reversible interaction.... | 12/22/2011 |
| 20110311507 | Methods for Diagnosing and Treating Autoimmune Disorders Provided herein are, inter alia, methods of identifying patients who are at risk of developing an autoimmune disorder, and treating patients suffering from autoimmune disorders.... | 12/22/2011 |
| 20110311609 | Wound healing device The invention is directed to a wound healing device. Such wound healing device utilizes novel wound healing compositions embedded onto or into a natural plant-derived cloth-based matrix.... | 12/22/2011 |
| 20110311508 | METHOD OF MODULATING HSF-1 The present invention is directed to methods of modulating HSF1 activity comprising modifying the acetylation of the DNA binding domain of the HSF1.... | 12/22/2011 |
| 20110305683 | Stabilization Of Perhydrolases Disclosed herein is a method for stabilization of the perhydrolase activity of the CE-7 esterase in a formulation with a carboxylic acid ester that employs the addition of a buffering agent, substantially undissolved, to the mixture of the CE-7 esterase and the carboxyl... | 12/15/2011 |
| 20110300109 | COMPOSITIONS AND METHODS FOR TREATING CANCER The present invention is based, in part, on our discovery of compositions and methods that can be used to systemically deplete arginine and thereby treat arginine-dependent cancers. Our studies indicate that administering a composition that depletes arginine directly to... | 12/08/2011 |
| 20110300201 | DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE The invention provides methods, compositions, systems, and kits that include an enzyme/substrate co-delivery system. The liquid delivery system includes at least one enzyme encapsulated in a water-soluble polymeric matrix and a substrate for the enzyme in a carrier liqu... | 12/08/2011 |
| 20110293595 | Prophylactic and therapeutic treatment of Alzheimer's Disease, neuro-degenerative diseases, protein aggregation diseases, Parkinson's Disease and amyloid diseases, using phytic acid and phytate A composition and method for the treatment of Alzheimer's Disease, and/or related protein aggregation diseases and/or amyloidoses and/or a neuro-degenerative disease, and/or Parkinson's Disease and/or Parkinsonism including an effective amount of a compound selected fro... | 12/01/2011 |
| 20110293594 | REMOVAL OF SERINE PROTEASES BY TREATMENT WITH FINELY DIVIDED SILICON DIOXIDE The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for manufacturing plasma-derived protein compositions having reduced serine protease a... | 12/01/2011 |
| 20110293596 | DISEASE CONTROL WITH TICK PHOSPHOLIPASE A2 The present invention relates to reagents and methods for the modulation of viability of bacteria. A process is provided wherein a protein sequence from A. americanum saliva effective in reducing the viability of gram positive, gram negative, or acid-fast bacteri... | 12/01/2011 |
