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| Application No. | Application Title | Issue Date |
| 20120128650 | EXTENDED ACTING OXYGEN GENERATING COMPOSITION FOR TREATING MICROBIAL INFECTIONS A medicament for the treatment or prevention of a microbial infection or an associated condition in a low oxygen environment characterised in that the medicament includes an extended acting oxygen generating system.... | 05/24/2012 |
| 20120130144 | TREATMENT OF LUNG CANCER WITH A NITROBENZAMIDE COMPOUND IN COMBINATION WITH A GROWTH FACTOR INHIBITOR In one aspect, the present invention provides a method of treating lung cancer, comprising administering to a subject at least one PARP inhibitor in combination with at least one growth factor inhibitor. In another aspect, the present invention provides a method of trea... | 05/24/2012 |
| 20120107230 | Treatment of Hyperproliferative Diseases with Vinca Alkaloid N-Oxide Analogs The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination ... | 05/03/2012 |
| 20120082632 | Topical drug delivery system with dual carriers A drug delivery system, formed as a tissue penetrating solution, comprising:
| 04/05/2012 |
| 20120082654 | Method For Preventing And Controlling Organisms That Infest Aqueous Systems Method for preventing and controlling organisms that infest aqueous systems in which one or more organic or inorganic compounds capable of releasing gas are present, comprising the step of dispersing on and/or in the aqueous mass a preparation comprising enzymes adapted... | 04/05/2012 |
| 20120082717 | COMPLEX, MULTILAYER USING THE SAME, AND DEVICE COATED WITH THE MULTILAYER Disclosed herein is a complex, wherein micelles and/or liposomes dispersed in hyaluronic acids and/or hyaluronic acid derivatives, with a drug and/or functional material loaded in the micelles and/or the liposomes. The complex can release the drug and/or functional mate... | 04/05/2012 |
| 20120083772 | CORNEAL TREATMENT SYSTEM AND METHOD A system for bilateral or monocular photochemical cross-linking of corneal collagen employs selectable light in a selected wavelength band as the excitation source and riboflavin as the photosensitizer. The system has an illumination source which may have multi-spectral... | 04/05/2012 |
| 20120052022 | COMPOSITION FOR ORAL HEALTH TREATMENT AND RELATED METHODS OF USE The present invention provides compositions and related methods for oral health treatment of a subject. Compositions of the invention include an anti-oxidant enzyme, an anti-inflammatory agent, and a pharmaceutically acceptable buffer. In certain embodiments, the compos... | 03/01/2012 |
| 20120039888 | Methods Of Inhibiting Inflammation-Associated Tissue Damage By Inhibiting Neutrophil Activity The present invention relates to compositions and methods for treating inflammation-associated tissue damage, and particularly transfusion-associated, disorders, by inhibiting or reducing E-selectin mediated signal transduction pathways, such as E-selectin mediated acti... | 02/16/2012 |
| 20120034203 | Methods for Killing or Inhibiting Growth of Mycobacteria The present invention provides a method for killing or inhibiting growth of Mycobacteria, by contacting the Mycobacteria with a haloperoxidase, hydrogen peroxide, chloride ions and/or bromide ions, and ammonium ions.... | 02/09/2012 |
| 20120034222 | Nitric Oxide Generating Medical Devices Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided.... | 02/09/2012 |
| 20120020946 | Methods for Inactivating Viruses The present invention provides a method for inactivating viruses, by contacting the viruses with a haloperoxidase, hydrogen peroxide, chloride ions, bromide ions, and ammonium ions.... | 01/26/2012 |
| 20120014879 | USE OF TUMOR NECROSIS FACTOR-alpha RECEPTOR p75 FOR TREATMENT OF ISCHEMIA-INDUCED NEOVASCULARIZATION Improvements on the basic method used for BEAMing increase sensitivity and increase the signal-to-noise ratio. The improvements have permitted the determination of intrinsic error rates of various DNA polymerases and have permitted the detection of rare and subtle mutat... | 01/19/2012 |
| 20120003300 | Composition Comprising Vascular Endothelial Growth Factor (VEGF) for the Treatment of Hair Loss A composition to treat hair loss and enhance hair growth and condition. The composition comprises: i) one or more of VEGF, a VEGF biomimetic peptide, and/or a VEGFR2 receptor agonist; ii) ciclopirox olamine; and iii) a pharmaceutically acceptable carrier.... | 01/05/2012 |
| 20120003291 | NANOBEAD RELEASING MEDICAL DEVICES Medical devices comprising nanobeads encapsulating one or more bioactive agents and methods of use thereof are provided.... | 01/05/2012 |
| 20120003207 | METHODS AND COMPOSITIONS FOR MODULATING PROLINE LEVELS Methods and compositions for modulating amino acid levels in a subject are provided herein.... | 01/05/2012 |
| 20110300201 | DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE The invention provides methods, compositions, systems, and kits that include an enzyme/substrate co-delivery system. The liquid delivery system includes at least one enzyme encapsulated in a water-soluble polymeric matrix and a substrate for the enzyme in a carrier liqu... | 12/08/2011 |
| 20110300109 | COMPOSITIONS AND METHODS FOR TREATING CANCER The present invention is based, in part, on our discovery of compositions and methods that can be used to systemically deplete arginine and thereby treat arginine-dependent cancers. Our studies indicate that administering a composition that depletes arginine directly to... | 12/08/2011 |
| 20110293592 | METHOD OF TREATING CORONARY ARTERIES WITH PERIVASCULAR DELIVERY OF THERAPEUTIC AGENTS A method of treating the intraluminal disease in a coronary artery by injecting therapeutic agents perivascularly into the myocardium near the site of disease.... | 12/01/2011 |
| 20110286990 | METHODS OF DIAGNOSING AND TREATING FIBROSIS The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Ag... | 11/24/2011 |
| 20110286991 | PEPTIDES DERIVED FROM HMG-COA REDUCTASE AND COSMETIC AND/OR PHARMACEUTICAL COMPOSITION CONTAINING SAME The present invention relates to peptides derived from human HMG-CoA reductase of general formula (I):
| 11/24/2011 |
| 20110286992 | PERSONAL CARE COMPOSITION CONTAINING LEGHEMOGLOBIN A personal care composition comprising leghemoglobin and at least one preservative selected from the group consisting of alcohols, glycols, parabens, hydantoins, quaternary nitrogen-containing compounds, isothiazolinones, aldehyde-releasing agents, and halogenated compo... | 11/24/2011 |
| 20110287061 | Dietary composition and method for promoting healthy hair growth and melanogenesis A dietary composition for promoting melanogenesis in hair of a user comprising approximately 5,000 IU per day of catalase, a synergistic core component, 5-α-reductase inhibitors, an antioxidant component, and approximately 200 mg per day of L-tyrosine. Preferably, the ... | 11/24/2011 |
| 20110280855 | VITAMIN C COMPOSITIONS The field of invention relates to Vitamin C compositions, and in particular to Vitamin C compositions containing ascorbate-glucose transport enhancers. In at least one aspect, a composition is provided herein that includes ascorbate in an amount from about 0.1% by weigh... | 11/17/2011 |
| 20110274680 | Chemical composition and its delivery for lowering the risks of alzheimer's, cardiov ascular and type-2 diabetes diseases Synergistic chemical compositions of bioactive compounds in a dietary supplement for lowering the risks of Alzheimer's, Cardiovascular and Diabetes diseases; chemical compositions of a sugar free super sweetener for people with Type-2 Diabetes disease and a targeted nan... | 11/10/2011 |
| 20110274738 | FUNCTIONALIZED CHEMICALLY INERT POLYMERS FOR COATINGS Provided herein are methods for functionalizing a polymer for forming a coating and coatings and devices formed thereof or for functionalizing a coating or device surface including an polymer.... | 11/10/2011 |
| 20110268719 | Annatto Extract Compositions, Including Geranyl Geraniols And Methods Of Use Annatto extract composition (AEC), including cis and trans geranyl geraniols (GG) and tocopherol-free C-5 unsubstituted tocotrienols (T3), increases the de novo synthesis of intermediate isoprenoid and distal protein products, including endogenous coenzyme Q10 (CoQ10), ... | 11/03/2011 |
| 20110268713 | Variants of Ancestral Uricases and Uses Thereof The present invention provides uricases and methods of their production and use in reducing the amount of uric acid in a subject. The present invention further provides methods employing a uricase of this invention in the treatment and/or prevention of hyperuricemia, go... | 11/03/2011 |
| 20110262505 | SEAWEED-DERIVED COSMETIC COMPOSITIONS A cosmetic composition is disclosed for applying to skin. The composition includes a liquid and dispersed in the liquid: any amount or form of fucoidan, any amount or form of beta glucan; and any amount of a marine extract. When the cosmetic composition is applied to th... | 10/27/2011 |
| 20110262420 | INHALANT COMPRISING MODIFIED SUPEROXIDE DISMUTASE An inhalant containing a lecithinized superoxide dismutase (hereinafter referred to as PC-SOD) which effectively exerts the effect of superoxide dismutase (SOD) as an active ingredient, particularly for treatment of idiopathic (acute) or chronic interstitial pneumonia, ... | 10/27/2011 |
| 20110262421 | PHARMACEUTICAL COMPOSITION, FOOD OR DRINK, OR FEED FOR INTESTINAL DISEASE It is intended to provide a pharmaceutical composition, a food or drink, or a feed which has an effect on the prevention and/or treatment of an intestinal disease such as ulcerative colitis, Crohn's disease or irritable bowel syndrome. A preferred embodiment is the phar... | 10/27/2011 |
| 20110265198 | Genome editing of a Rosa locus using nucleases Disclosed herein are methods and compositions for genome editing of a Rosa locus, using fusion proteins comprising a DNA binding domain and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprisin... | 10/27/2011 |
| 20110243911 | USE OF A COMPOUND CAPABLE OF REDUCING THE URIC ACID LEVEL FOR THE PREVENTION AND/OR THE TREATMENT OF LUNG INFLAMMATION AND FIBROSIS The present invention is directed to the use of a compound capable of reducing the uric acid level in a mammal for the prevention and/or the treatment of IL-1β driven lung pathology, particularly to treat lung inflammation such as chronic fibrosis, COPD and interstitia... | 10/06/2011 |
| 20110244017 | Absorbable Coating For Implantable Device The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.... | 10/06/2011 |
| 20110236394 | METHODS FOR THE REGULATION OF THE PROSTAGLANDIN F SYNTHASE (PGFS) ACTIVITY OF AKR1B1 AND USES THEREOF AKR1B1 (EC 1.1.1.21) is an aldose reductase that has mainly been associated with the polyol pathway, and more recently with lipid deperoxidation. We have discovered that the primary activity of this enzyme is rather a PGFS activity, catalyzing the transformation of PGH<... | 09/29/2011 |
| 20110236365 | METHOD FOR PROTECTING AND TREATING AT LEAST ONE MUSCARINIC RECEPTOR FROM DYSFUNCTION RESULTING FROM FREE RADICAL DAMAGE Methods and compositions for enhancing cellular function through protection of a tissue components such receptors, proteins, lipids, nucleic acids, carbohydrates, hormones, vitamins, and cofactors, by administering pyrophosphate analogs or related compounds.... | 09/29/2011 |
| 20110229598 | Enhanced lactoperoxidase system for treatment of milk products The present invention relates to treatment of milk and milk products such as waste-milk with an enhanced lactoperoxidase system. The enhanced lactoperoxidase system is activated by the addition of a hydrogen peroxide source and an oxidizable agent, such as a halide to t... | 09/22/2011 |
| 20110229449 | PROPHYLAXIS AND TREATMENT OF MACULAR DEGENERATION AND RETINOPATHY USING A PRDX PROTEIN The present invention provides an agent for the prophylaxis or treatment of retinopathy or AMD containing PRDX 5 or PRDX 6, as well as an agent for the prophylaxis or treatment of retinopathy or AMD containing a polynucleotide encoding PRDX 5 or PRDX 6. The present inve... | 09/22/2011 |
| 20110223230 | HYDROGEL FORMULATIONS A polymeric prodrug composition including a hydrogel, a biologically active moiety and a reversible prodrug linker. The prodrug linker covalently links the hydrogel and the biologically active moiety at a position and the hydrogel has a plurality of pores with openings ... | 09/15/2011 |
| 20110217279 | USE OF HUMAN BILIVERDIN REDUCTASE AND FRAGMENTS THEREOF FOR THE TREATMENT OF PROTEIN KINASE C-DELTA AND ERK RELATED CONDITIONS The present invention is directed to methods of modulating PKC-δ activity and PKC-δ/ERK complex activity in cells via biliverdin reductase. Methods and compositions for diagnosing and treating a PKC-δ and PKC-δ/ERK complex related condition are also disclosed.... | 09/08/2011 |
