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| Application No. | Application Title | Issue Date |
| 20120128726 | INFANT FEEDING FORMULAS COMPRISING PROBIOTIC MICRO-ORGANISMS The present invention relates to the field of infant nutrition. In particular, the present invention relates to infant feeding formulas comprising probiotic micro-organisms. These probiotic micro-organisms may be non-replicating probiotic micro-organisms such as bioacti... | 05/24/2012 |
| 20120130303 | RATE CONTROL DURING AF USING CELLULAR INTERVENTION TO MODULATE AV NODE A biologic intervention method and apparatus generates a persistent modification to an AV node that is physiologically stable after the agent has matured but is alterable with subsequent application of an agent. Specifically, the generic agent is used to modulate a node... | 05/24/2012 |
| 20120108425 | BIOSYNTHESIS OF GOLD AND SILVER NANOPARTICLES FOR STABILITY AND EXTENDED SHELF-LIFE OF ANTAGONISTIC ACTIVITIES The use of microbial nanoparticles to stabilize antifungal activity is described. The preferred silver and gold nanoparticles are formed from various categories of microbes like bacteria, fungi and actinomycetes. The silver and gold nanoparticles synthesized from microb... | 05/03/2012 |
| 20120107394 | IMMUNO-COMPATIBLE HYDROGEL SYSTEM An immuno-compatible hydrogel system is provided that is resistant to protein binding. The hydrogel system is prepared by contacting a hydrogel solution with a cross-linking agent to form a gel, exposing the gel to an aqueous solution comprising a first polyelectrolyte ... | 05/03/2012 |
| 20120083412 | Composition and Method for Delivery of Substances in a Dry Mode Having a Surface Layer The present invention generally relates to compositions and methods of delivering substances in a dry mode, wherein the compositions include a surface layer disposed on the outer surface of the composition that is permeable to carbon dioxide and oxygen. The compositions... | 04/05/2012 |
| 20120070427 | VORTEX-INDUCED SILK FIBROIN GELATION FOR ENCAPSULATION AND DELIVERY The present invention provided for a novel process of forming silk fibroin gels, and controlling the rate of β-sheet formation and resulting hydrogelation kinetics, by vortex treatment of silk fibroin solution. In addition, the vortex treatment of the present invention... | 03/22/2012 |
| 20120045416 | Nutritional therapy method and dietary supplement food to restore compromised, ileal lymphoid nodular hyperplasia in autistic children A nutritional therapy method to restore mesolimbic compromised, ileal lymphoid nodular hyperplasia in autistic children includes: dietary restriction of casein, gluten, opiatic peptides and branched chain amino acid and the herein described nutritional therapy solution ... | 02/23/2012 |
| 20120045394 | HUMAN AND MOUSE TARGETING PEPTIDES IDENTIFIED BY PHAGE DISPLAY The present invention concerns methods and compositions for in vivo and in vitro targeting. A large number of targeting peptides directed towards human organs, tissues or cell types are disclosed. The peptides are of use for targeted delivery of therapeutic agents, incl... | 02/23/2012 |
| 20120045458 | USE OF NOTCH REGULATORS FOR MODULATING THE IMMUNE RESPONSE BY INDUCTION/SUPPRESSION OF INTERLEUKIN-22 The invention relates to the use of notch regulators for modulating IL-22 production in T-cells, by influencing the activity or activation of the notch signal path. The invention further relates to the use of modulating the immune response, primarily in case of infectio... | 02/23/2012 |
| 20120039956 | DRY STORAGE STABILIZING COMPOSITION FOR BIOLOGICAL MATERIALS The present invention includes compositions and drying methods for preserving sensitive bioactive materials, such as peptides, proteins, hormones, nucleic acids, antibodies, drugs vaccines, yeast, bacteria (probiotic or otherwise), viruses and/or cell suspensions, in st... | 02/16/2012 |
| 20120039851 | USE OF ANDROGENS FOR VASCULAR REGENERATION AND ENDOTHELIAL REPAIR The present invention relates to the field of therapy and prophylaxis of vascular tissue damage and/or complications and/or disease of vascular tissue by vascular regeneration and endothelium repair. The inventors have found that administration of an androgen receptor a... | 02/16/2012 |
| 20120039944 | WHEY AND THYMUS FUNCTION The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that can be used to maintain or improve thymus health. One embodiment of the present invention is the use of whey or at least one pr... | 02/16/2012 |
| 20120034291 | NANOIMPRINTING OF SILK FIBROIN STRUCTURES FOR BIOMEDICAL AND BIOPHOTONIC APPLICATIONS The present invention provides for photonic nanoimprinted silk fibroin-based materials and methods for making same, comprising embossing silk fibroin-based films with photonic nanometer scale patterns. In addition, the invention provides for processes by which the silk ... | 02/09/2012 |
| 20120027732 | THERMOREVERSIBLE COLLAGEN This invention relates to collagen formulations. More particularly, this invention relates to thermoreversible collagen formulations and methods of their use and preparation.... | 02/02/2012 |
| 20120027724 | METHODS OF TREATING IMPAIRED GLUCOSE METABOLISM VIA ADMINISTRATION OF ALGAL BIOMASS The invention is directed to methods of using Chlorella protothecoides microalgal biomass in the treatment of individuals having impaired glucose metabolism. In some cases, the patient has impaired fasting glucose, impaired glucose tolerance, or diabetes. In some... | 02/02/2012 |
| 20120027735 | SYMBIOTIC MAPLE PRODUCT COMPOSITIONS AND METHODS The present invention relates to novel maple product compositions. In particular, the present invention relates to new compositions comprising maple sap, maple concentrate, maple syrup or diluted maple syrup, and probiotics, prebiotics or combinations thereof. The prese... | 02/02/2012 |
| 20120009152 | NITRIC OXIDE DONORS FOR TREATMENT OF DISEASE AND INJURY A method of promoting neurogenesis by administering a therapeutic amount of a phosphodiesterase inhibitor compound to a patient in need of neurogenesis promotion. A compound for providing neurogenesis having an effective amount of a phosphodiesterase inhibitor sufficien... | 01/12/2012 |
| 20120009248 | Preservation of Bioactive Materials By Spray Drying This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stab... | 01/12/2012 |
| 20120010557 | Drug Delivery System for Use in the Treatment of Vascular and Vessel-Related Pathologies The present invention relates to a drug delivery system for use in the treatment of vascular and vessel-related pathologies, comprising a drug delivery platform that comprises at least one compound capable of exerting an effect on the formation and/or maintenance of a t... | 01/12/2012 |
| 20120003193 | Methods and Apparatus for Manufacturing Plasma Based Plastics and Bioplastics Produced Therefrom Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; m... | 01/05/2012 |
| 20110311486 | 1,2,4-OXADIAZOLE BENZOIC ACID COMPOSITIONS Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature t... | 12/22/2011 |
| 20110311591 | Antimicrobial Coating A substrate (100) comprising a sol-gel derived coating (101). The coating, is chemically bonded to the substrate (100) and is derived from a polysiloxane to form a network of silicon-carbon and silicon-oxygen bonds. An antimicrobial is releasably captured within the net... | 12/22/2011 |
| 20110305732 | METHODS AND USES FOR INHIBITING PLATELET COAGULATION The present disclosure provides methods and uses of Slit proteins and nucleic acids for inhibiting platelet coagulation and related disorders. Further provided is a vascular device coated with Slit protein or a cell expressing a Slit protein.... | 12/15/2011 |
| 20110300106 | THERAPEUTIC AMOEBA AND USES THEREOF The present invention relates to amoebae (slime molds) and uses thereof. In particular, the present invention relates to the use of amoebae or their environmentally stable spores to treat microbial infections and other uses.... | 12/08/2011 |
| 20110293562 | USE OF CARDIOTROPHIN-1 FOR THE TREATMENT OF METABOLIC DISEASES The invention is related to the use of cardiotrophin-1 (CT-1) for the treatment of obesity and associated disorders: hyperglycaemias, insulin resistance, development of type 2 diabetes and dyslipemias and given its anorexigenic role, fat oxidation stimulant, hypoglycaem... | 12/01/2011 |
| 20110293722 | HYDROGEL SPONGES, METHODS OF PRODUCING THEM AND USES THEREOF A macroporous hydrogel sponge is provided selected from: (i) a synthetic polymer hydrogel sponge, and (ii) a synthetic polymer-polypeptide conjugate hydrogel sponge, the macroporous hydrogel sponge being at least 20% porous and having a pore diameter of 50-1000 μm, whe... | 12/01/2011 |
| 20110286980 | METHODS FOR INDUCING SELECTIVE APOPTOSIS Provided herein are methods for cell therapy by modifying transfused cells to express an inducible caspase 9 protein, so that the cells may be selectively killed if the patient experiences dangerous side effects. Provided also within relates in part to methods for preve... | 11/24/2011 |
| 20110288651 | Supercritical Carbon-Dioxide Processed Biodegradable Polymer Nanocomposites A biodegradable nanocomposite and a method of forming a biodegradable nanocomposite are provided. In one aspect, the biodegradable nanocomposite includes a biodegradable polymer and a reinforcing agent substantially dispersed throughout the biodegradable polymer by rapi... | 11/24/2011 |
| 20110280944 | FIBROUS MICROCAPSULES AND METHODS OF ASSEMBLY AND USE THEREOF The present invention relates to assembly of peptide amphiphiles and biopolymers into fibrous microcapsules, and uses thereof. In particular, the present invention provides devices, compositions, and methods for interfacial self-assembly of peptide amphiphiles and biopo... | 11/17/2011 |
| 20110280834 | METHODS AND COMPOSITIONS FOR CARDIAC TISSUE REGENERATION Methods for treating an injured cardiac tissue in a subject are provided herein. Methods for improving survival, engraftment and proliferation of stem cells in a cardiac tissue are provided. Also provided are methods for generating cardiac cells. Further provided are co... | 11/17/2011 |
| 20110280915 | ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.... | 11/17/2011 |
| 20110262541 | FOAM-FORMED COLLAGEN STRAND Foam-formed collagen strands and methods for forming strands involve depositing a dispersed solution of an isolated cleaned, de-fatted, enzymatically-treated (or non-enzyme treated) human-derived collagen product having a preserved amount of its natural constituents int... | 10/27/2011 |
| 20110262447 | HUMAN SYNTHETIC SINGLE-CHAIN ANTIBODIES DIRECTED AGAINST THE COMMON EPITOPE OF MUTANT P53 AND THEIR USES Isolated polypeptides, isolated polynucleotides or expression vectors encoding same, viral display vehicles which can be specifically bind an exposed epitope shared by mutant, but not wild type, p53 protein are provided. Also provided are methods of inducing apoptosis a... | 10/27/2011 |
| 20110256100 | SECRETED MODULAR CALCIUM BINDING PROTEIN FOR INTRACELLULAR MODULATION OF BONE MORPHOGENETIC PROTEIN SIGNALING A method for modulating Bone Morphogenetic Protein (BMP) signaling activity in a cell or tissue of a vertebrate subject is provided which comprises administering a polynucleotide or polypeptide encoding a Secreted Modular Calcium Binding Protein (SMOC) polypeptide, or a... | 10/20/2011 |
| 20110257504 | BIOLOGICALLY INTEGRATED ELECTRODE DEVICES Bioelectrodes having enhanced biocompatible and biomimetic features are provided. Methods of making and using the bioelectrodes are further provided. A biologically integrated bioelectrode device and method for detecting electronic signals using a bioelectrode comprisin... | 10/20/2011 |
| 20110256222 | Recombinant Protein Enriched in a Heparin Binding Site and/or in a Heparan Sulfate Binding Site The invention relates to a recombinant protein enriched in a heparin binding site and/or a heparan sulfate binding site. Such recombinant protein is used as an in vivo controlled release system of a protein of interest.... | 10/20/2011 |
| 20110250178 | COSMETIC COMPOSITIONS COMPRISING MICROALGAL COMPONENTS The invention provides cosmetic compositions comprising microalgal biomass, whole microalgal cells, and/or microalgal oil in combination with one or more other cosmetic ingredients, and methods of making such compositions. In preferred embodiments, the microalgal compon... | 10/13/2011 |
| 20110240512 | Antibiotic Formulations Providing Reduced Gastrointestinal Side Effects and Clostridium difficile Infection Relapse, and Related Methods The invention includes a formulation comprising: (i) a therapeutically effective amount of at least one antibiotic; and (ii) a therapeutically effective amount of at least one probiotic material. The formulation is prepared in a dosage form for delivery to the gastroint... | 10/06/2011 |
| 20110236457 | Micronized Device for the Delivery of Biologically Active Molecules and Methods of Use Thereof The invention provides micronized encapsulated cell therapy devices that are capable of delivering a biologically active molecule to the eye. Also provided are methods of using the same to deliver biologically active molecules to the eye and to treat ophthalmic disorder... | 09/29/2011 |
| 20110229549 | Methods and Compositions for Enhancing Vascular Access Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arterioveno... | 09/22/2011 |
