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| Application No. | Application Title | Issue Date |
| 20120107264 | NUCLEIC ACID DELIVERY COMPOUNDS Polymers including two or more different recurring units are disclosed herein. Also disclosed herein are methods of using such polymers to deliver nucleic acids to a cell.... | 05/03/2012 |
| 20120052006 | GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF The present disclosure is directed generally to gold/lanthanide nanoparticle conjugates, such as gold/gadolinium nanoparticle conjugates, nanoparticle conjugates including polymers, nanoparticle conjugates conjugated to targeting agents and therapeutic agents, and their... | 03/01/2012 |
| 20120003176 | HYDROGEL-FORMING COMPOSITION COMPRISING NATURAL AND SYNTHETIC SEGMENTS A hydrogel composition is formed from a natural polymer derivative having a plurality of cross-linkable units depending therefrom, and a synthetic polymer derivative having a plurality of cross-linkable units depending therefrom, said natural and synthetic polymer deriv... | 01/05/2012 |
| 20110293675 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.... | 12/01/2011 |
| 20110200655 | Systems and methods that kill infectious agents (bacteria) without the use of a systemic anti-biotic A medical product is provided that is selected from at least one of, nasal cannulas, oxygen masks, wound dressings, bandages, band aids, catheters, endotrachial tubes, condoms, surgical and other gloves, sheaths for endoscopy probes, and medical products that physically... | 08/18/2011 |
| 20110171167 | Isocyanate-Based Compositions and Their Use The present disclosure describes a method and a kit for bulking, augmenting or occluding a tissue comprising administering a sufficient amount of a composition containing a biocompatible, non-bioabsorbable isocyanate-based material onto or into tissue.... | 07/14/2011 |
| 20110165114 | DRUG DELIVERY COMPOSITION There is provided a non-water soluble drug delivery composition comprising a conjugate and a polymer matrix wherein exposure of the composition to electromagnetic radiation at a suitable pre-determined wavelength and intensity induces release of the active ingredient fr... | 07/07/2011 |
| 20110142764 | CONJUGATES OF A POLYMER, A BISPHOSPHONATE AND AN ANTI-ANGIOGENESIS AGENT AND USES THEREOF IN THE TREATMENT AND MONITORING OF BONE RELATED DISEASES Conjugates of polymers or copolymers having attached thereto an anti-angiogenesis agent and a bisphosphonate bone targeting agent, and processes of preparing same, are disclosed. Pharmaceutical compositions containing these conjugates and u... | 06/16/2011 |
| 20110135831 | BIOSTATIC POLYMER Methods and compositions effective for at least a week for prevention of microbial colony growth on a surface, for example an inanimate surface, where the surface is covered with a dry or substantially dry film formed from a composition comprising a polyvinyl alcohol an... | 06/09/2011 |
| 20110117164 | Use of Additive Sites to Control Nitric Oxide Release from Nitric Oxide Donors Contained within Polymers A method for increasing, prolonging, and/or controlling the release rates of nitric oxide (NO) from polymeric materials containing NO adducts. Such NO-containing polymeric materials may find use in devices such as blood contacting devices, and biocompatible devices util... | 05/19/2011 |
| 20110110882 | CROSS-LINKED COMPOSITIONS Improved compositions comprising a cross-linkable protein or polypeptide, and a non-toxic material which induces cross-linking of the cross-linkable protein. The compositions are optionally and preferably prepared in a non-phosphate buffer solvent. Optionally and prefer... | 05/12/2011 |
| 20110097376 | RADIOPAQUE INJECTABLE NUCLEUS HYDROGEL COMPOSITIONS A composition suitable for use as replacement material for all or part of a disc nucleus during percutaneous injection, the composition comprising:
| 04/28/2011 |
| 20110076246 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE Sulfur-containing ligands and methods of their utilization for binding metals and/or main group elements and removing them from fluids, solids, gases and/or tissues are disclosed. The ligands are of the general structure: 03/31/2011 | |
| 20110014292 | METHOD OF PROPHYLAXIS AND AGENTS FOR USE THEREIN The present invention relates generally to a method of prophylactically or therapeutically treating antigen-induced airway tissue inflammation and agents for use therein. More particularly, the present invention provides a method of prophylactically or therapeutically t... | 01/20/2011 |
| 20100330143 | MODIFIED MACROMOLECULES AND METHODS OF MAKING AND USING THEREOF Described herein are composites produced by reacting a first thiolated macromolecule with at least one compound having at least one thiol-reactive electrophilic functional group. The methods described herein permit the cross-linking of a variety of different thiolated m... | 12/30/2010 |
| 20100136077 | BIOCIDIC HOUSEHOLD CLEANSING MATERIALS The present invention discloses household cleaning materials comprising at least one insoluble proton sink or source (PSS) and to method for utilizing the PSS as a biocidic agent. The household cleaning materials are provided useful for killing living target cells (LTCs... | 06/03/2010 |
| 20100062968 | Novel strategies for delivery of active agents using micelles and particles The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles... | 03/11/2010 |
| 20100003212 | POLYMERS WITH ANTIMICROBIAL ACTIVITY CONTAINING QUATERNARY AMMONIUM GROUPS The present invention relates to novel articles and the like, typically exhibiting antimicrobial efficacy which articles contain for example a carrier, a spacer attached to the carrier and one or more quaternary ammonium groups attached directly or indirectly to said sp... | 01/07/2010 |
| 20090136443 | Drug Carrier The present invention has an object of providing a drug carrier capable of controlling in vivo pharmacokinetics. The present invention is directed to a drug carrier comprising a molecular assembly having a drug incorporated therein, and the above object can be achieved ... | 05/28/2009 |
| 20090098083 | CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.... | 04/16/2009 |
| 20090011004 | IMPROVED CARRIERS FOR DELIVERY OF NUCLEIC ACID AGENTS TO CELLS AND TISSUES This invention relates to drug delivery and specifically to the preparation and use of functionalized carriers such as nanopolymers and nanovesicles for improved delivery of nucleic acid agents (NAA) to tissues and cells. These compounds have broad applicability for tre... | 01/08/2009 |
| 20080226583 | THERAPEUTIC POLYESTERS AND POLYAMIDES Polymers (i.e. polyesters, polyamides, and polythioesters or a mixture thereof) which degrade hydrolytically into biologically active compounds are provided. Methods of producing these polymers, intermediates useful for preparing these polymers, and methods of using the... | 09/18/2008 |
| 20080152616 | Amphiphilic block copolymer and polymeric compostition comprising the same for drug delivery The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relat... | 06/26/2008 |
| 20080124299 | METHODS FOR TREATING VIRAL INFECTION USING IL-28 AND IL-29 IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on viruses that infect liver, such as hepatitis B virus and hepatitis C virus. In ... | 05/29/2008 |
| 20080118460 | Conjugates of polymer and pharmacologically active agents and a novel polymer blend The instant invention provides a novel conjugate of a synthetic, biodegradable, exceedingly hydrophilic and non-proteinaceous polymer, whereby each of the above attributes is defined in the specification, and various pharmacologically active agents. The instant inventio... | 05/22/2008 |
| 20080112918 | Method for treating gout and binding uric acid A method for treating gout and/or reducing serum uric acid levels in a patient is disclosed that includes administering to the patient a therapeutically effective amount of an amine polymer, for example, an aliphatic amine polymer. In one embodiment, the polymer binds t... | 05/15/2008 |
| 20080112919 | TNP-470 POLYMER CONJUGATES AND USE THEREOF The present invention relates to conjugates of water-soluble polymers and o-(chloracetyl-carbamoyl) fumagillol (TNP-470) and use of those conjugates as specific intracellular carriers of the TNP-470 into tumor vessels. The present invention further relates to use of tho... | 05/15/2008 |
| 20080112891 | Encapsulated (Chelate or Ligand) Dendritic Polymers An encapsulated chelate dendritic polymer and an encapsulated ligand dendritic polymer are disclosed which have unique properties. These encapsulated chelate dendritic polymers may have associated with its dendritic polymer surface target directors, proteins, DNA, RNA (... | 05/15/2008 |
| 20080112917 | Sphingolipids' Polyalkylamines Conjugates The present invention concerns novel sphingolipid-polyalkylamines conjugates, a process for their preparation and pharmaceutical compositions comprising the same. In particular, the present invention concerns ceramide based polyalkylamine c... | 05/15/2008 |
| 20080107618 | USE OF FULLERENES FOR THE TREATMENT OF MAST CELL AND BASOPHIL-MEDIATED DISEASE Mast cell (MC) and peripheral blood basophil (PBB)-associated diseases are treated or prevented, or their symptoms are alleviated by the administration of water soluble fullerenes (buckeyballs) to the individual under conditions sufficient to inhibit MC and PBB response... | 05/08/2008 |
| 20080075689 | Aqueous Preparations Comprising at Least One Water-Soluble or Water-Dispersible Copolymer with Cationgenic Groups The present invention relates to aqueous preparations comprising at least one water-soluble or water-dispersible copolymer with cationogenic groups which comprises at least one monomer with at least one protonatable nitrogen atom and at least one further monomer copolym... | 03/27/2008 |
| 20080057025 | Method for promoting bone formation Amine polymers, particularly aliphatic amine polymers, are useful in the treatment and prevention of bone disease and in methods for promoting bone formation. Sevelemer, polyallylamine crosslinked with epichlorohydrin, which is sold under the tradename Renagel®, is the... | 03/06/2008 |
| 20080057024 | STIMULI RESPONSIVE POLYESTER AMIDE PARTICLES A composition including a solution suitable for introduction into a blood vessel comprising particles including a treatment agent and a tunable stimuli-responsive polymer. A method including introducing a delivery device into a blood vessel; and introducing a solution i... | 03/06/2008 |
| 20080025943 | Modified two-component gelation systems, methods of use and methods of manufacture Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and ... | 01/31/2008 |
| 20080003253 | Block copolymers including a methoxyethyl methacrylate midblock A block copolymer comprising a methoxyethyl methacrylate (MOEMA) midblock is provided for forming a coating a medical device for controlled release of a bioactive agent.... | 01/03/2008 |
| 20070292384 | Water soluble micelle-forming and biodegradable cyclotriphosphazene-taxol conjugate anticancer agent and preparation method thereof A water-soluble micelle-forming cyclotriphosphazene-taxol conjugate anticancer agent, which is biodegradable, and thus, slowly release taxol, represented by the following Formula 1: wherein R is selected from the group consisting of H,... | 12/20/2007 |
| 20070292469 | Antimicrobial composition A stabilized antimicrobial composition comprising (a) polymeric polyquaternary ammonium compounds and (b) an antimicrobial metal, such as elemental silver, alloys thereof or silver compounds. The antimicrobial composition may be used as a stand-alone composition, in an ... | 12/20/2007 |
| 20070286885 | Elastin-based copolymers A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.... | 12/13/2007 |
| 20070280987 | Bioactive polymers for imparting bioactive character to hydrophobic medical article surfaces According to an aspect of the present invention, bioactive polymers are provided which have (a) a hydrophilic bioactive portion and (b) at least one hydrophobic polymer group that is linked to the hydrophilic bioactive portion by a covalent linkage that contains a chain... | 12/06/2007 |
| 20070274945 | High molecular weight chelation structure A chelation structure and method of forming and using the chelation structure. The chelation structure has a backbone that includes a linear sequence of monomeric backbone units, at least one polymer side chain, and at least one chelator side chain. The side chains are ... | 11/29/2007 |
