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| Application No. | Application Title | Issue Date |
| 20120128743 | POLYMER PARTICLES The present invention relates to a method of forming polymer on the surface of polymer particles, the method comprising:
| 05/24/2012 |
| 20120128752 | MULTI-PHASE MICROPARTICLES AND METHOD OF MANUFACTURING MULTI-PHASE MICROPARTICLES The invention relates to a method of manufacturing multi-phase microparticles. The method comprises dissolving at least three different polymers in a volatile organic solvent to obtain a first solution. The first solution comprises at least two cloud points, wherein the... | 05/24/2012 |
| 20120128782 | Multicomponent Degradable Cationic Polymers Degradable polymers were synthesized that self-assemble with DNA to form particles that are effective for gene delivery. Small changes to polymer synthesis conditions, particle formulation conditions, and polymer structure provides significant changes to efficacy in a c... | 05/24/2012 |
| 20120128764 | CONTROLLED-RELEASE COMPOSITIONS COMPRISING A PROTON PUMP INHIBITOR The present invention relates to pharmaceutical compositions, and methods of preparing such compositions, comprising one or more populations of controlled-release particles comprising one or more proton pump inhibitors. The present invention also relates to pharmaceutic... | 05/24/2012 |
| 20120128771 | TIMED, PULSATILE RELEASE SYSTEMS A unit multiparticulate dosage form for delivering one or more basic, active pharmaceutical ingredients into the body in need of such medications to achieve target PK (pharmacokinetics) profiles is described. The dosage form comprises one or more multicoated drug partic... | 05/24/2012 |
| 20120128780 | NANOPARTICULATE BISPHOSPHONATE COMPOSITIONS Nanoparticulate bisphosphonate compositions, having an effective average particle size of less than 2000 nm, are described. The compositions are useful in treating bone resorption in a mammal.... | 05/24/2012 |
| 20120107407 | BONE GRAFT AND BIOCOMPOSITE FOR PROSTHETIC DENTISTRY A bone graft or biocomposite for treating osseous defects and neogenesis of bone which is a composite of a biodegradable polymer and granules of beta-tricalciumphosphate, further comprising as active ingredient and embedded in the biodegradable polymer a physiologically... | 05/03/2012 |
| 20120082729 | QUICK DISSOLVE COMPOSITIONS AND TABLETS BASED THEREON The invention provides a composition useful for making oral dosage forms capable of dissolving in the mouth in less than 40 seconds without the need for a conventional super disintegrant and having a friability of less than 1%; wherein the composition includes liquiflas... | 04/05/2012 |
| 20120082728 | MULTIFUNCTIONAL STEALTH NANOPARTICULES FOR BIOMEDICAL USE The present invention relates to the field of drug delivery nanosystems. More precisely, the present invention concerns a copolymer with advantageous properties for the outer coating of various nanoparticles. Said copolymer comprises at least three types of monomers wit... | 04/05/2012 |
| 20120082721 | Enteric coating The present invention refers to a dosage form comprising an enteric coating in a specific amount, and to the use of enteric coating compositions for preparing a dosage form. Furthermore, the present invention also relates to a process for the preparation of a solid oral... | 04/05/2012 |
| 20120082718 | Morphine Formulations Described is a pellet composition comprising a core element comprising morphine sulfate, a filler and a binder, wherein the morphine sulfate, calculated as the anhydrous form, comprises about 50 wt % to about 85 wt % of the total weight of the core element; and a coatin... | 04/05/2012 |
| 20120070503 | Nanoparticle-Based Targeted Drug Delivery For In Vivo Bone Loss Mitigation The present invention is directed to nanoparticle-based targeted drug delivery system for treatment of bone-loss. An enantiomeric phenothiazine is formulated into an in-vivo nanoparticle delivery system which may contain bone-targeting functionality. The nanoparticle fo... | 03/22/2012 |
| 20120052127 | EXPANDED POLYSTYRENE PARTICLES HAVING SKIN LAYER WITH SUPERIOR MOLDABILITY, METHOD FOR PREPARING THE SAME AND EXPANDED POLYSTYRENE MOLDED ARTICLE USING THE SAME Disclosed are an expanded polystyrene particle having a skin layer with superior moldability, a method for preparing the same, and an expanded polystyrene molded article using the same. Provided is an expanded polystyrene particle provided on the surface thereof with a ... | 03/01/2012 |
| 20120052120 | NANOTECHNOLOGY FORMULATION OF POORLY SOLUBLE COMPOUNDS Embodiments of the present invention are directed to articles of manufacture, spheres having a diameter of 50 to 500 nanometers which contain poorly soluble drugs and methods of making such spheres. Embodiments of the present invention have particular application for th... | 03/01/2012 |
| 20120045516 | COMPOSITION FOR PHOTODYNAMIC THERAPY COMPRISING A MACROMOLECULAR CAPSULE A composition for photodynamic therapy including a polymer capsule having a diameter of about 10 nm to about 2000 nm synthesized by copolymerization of a flat aromatic compound represented by Formula 1 (see the specification) and an organic compound represented by Formu... | 02/23/2012 |
| 20120040008 | PHARMACEUTICAL COMPOSITIONS OF METABOTROPIC GLUTAMATE 5 RECEPTOR (MGLU5) ANTAGONISTS Pharmaceutical compositions of metabotropic glutamate 5 receptor (mGlu5) antagonists or a pharmacologically acceptable salt thereof are disclosed. The compositions contain the therapeutic active compound with non-ionic polymer and ionic polymer, binder and fillers in ei... | 02/16/2012 |
| 20120040009 | PARTICULATE PHARMACEUTICAL COMPOSITION WITH AN OPIOID AND AN OPIOID ANTAGONIST The invention relates to a pharmaceutical composition comprising first particles and second particles, the first particles comprising at least one opioid or a pharmaceutically acceptable salt thereof, and the second particles comprising at least one opioid antagonist or... | 02/16/2012 |
| 20120027864 | COATED DRUG DELIVERY FORMULATIONS The invention relates generally to methods of making formulations for delivering biological agents to a patient. In one aspect, proliposomal drug-delivery systems for medicaments are provided. In another aspect, coated proliposomal formulations for poorly water soluble ... | 02/02/2012 |
| 20120027856 | PHARMACEUTICAL PRODUCT COMPRISING YEAST A pharmaceutical product containing an active pharmaceutical ingredient and having a controllable release of the active pharmaceutical ingredient. The pharmaceutical product comprises yeast that is capable of fermentation. The carbon dioxide production of the fermentati... | 02/02/2012 |
| 20120021059 | SOLID PREPARATION A solid preparation 1 comprises a drug-containing unit 2 containing a cationic drug, and a gel-forming layer 4, containing an anionic polymer, for covering the drug-containing unit 2 and forming a gel with absorbing water, and optionally an i... | 01/26/2012 |
| 20120015010 | Compositions Comprising Pigment Particles Entrapped In Collapsed Polymeric Microspheres, And Methods Of Making The Same Topical compositions containing pigment particles entrapped in microspheres are provided. Each of the microspheres contains a collapsed polymeric shell that has entrapped therein one or more pigment particles. The microsphere-entrapped pigment particles are characterize... | 01/19/2012 |
| 20120015037 | FUNCTIONALIZED NANOPARTICLE, METHOD FOR PREPARING THE SAME AND APPLICATION THEREOF The present invention relates to a new type of functionalized nanoparticles for drug delivery, comprising a type of polymer nanoparticles, a polymer stabilizer coating, and a drug, wherein said polymer stabilizer coating is coated on the surface of said type of polymer ... | 01/19/2012 |
| 20120015038 | ENTERICALLY COATED CYSTEAMINE, CYSTAMINE AND DERIVATIVES THEREOF The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects.... | 01/19/2012 |
| 20120009267 | NANOPARTICLE COMPOSITIONS AND METHODS FOR IMPROVED ORAL DELIVERY OF ACTIVE AGENTS Nanoparticles, compositions, and methods for the improved uptake of active agents are disclosed herein. The compositions contain a monodisperse population of nanoparticles, preferably including an active agent, where the nanoparticles are formed from a polymeric materia... | 01/12/2012 |
| 20120009254 | Respiratory Syncytial Virus Antigenic Compositions and Methods Multilayer films comprise polypeptide epitopes from RSV. The multilayer films are capable of eliciting an immune response in a host upon administration to the host. The multilayer films include at least one designed peptide that includes one or more polypeptide epitopes... | 01/12/2012 |
| 20110311639 | Facile Route to the Synthesis of Resorcinarene Nanocapsules Described is a direct method for the fabrication of resorcinarene nanocapsules by photopolymerization of compounds of formula (I), such as resorcinarene tetraalkene tetrathiol (RTATT), in the absence of any template or preorganization. Further, by varying the polymeriza... | 12/22/2011 |
| 20110311631 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION WITH RESISTANCE AGAINST THE INFLUENCE OF ETHANOL EMPLOYING A COATING COMPRISING A POLYMER MIXTURE AND EXCIPIENTS The invention relates to a controlled release pharmaceutical composition, comprising a core, comprising a pharmaceutical active ingredient, whereby the core is coated by an ethanol resistance conferring coating layer which has the effect of conferring the release profil... | 12/22/2011 |
| 20110311620 | NOVEL MODIFIED RELEASE DOSAGE FORMS OF XANTHINE OXIDOREDUCTASE INHIBITOR OR XANTHINE OXIDASE INHIBITORS The present disclosure relates to novel dosage forms of xanthine oxidoreductase inhibitors.... | 12/22/2011 |
| 20110305766 | Method for Controlled Release of Parathyroid Hormone from Encapsulated Poly(Lactic-Glycolic)Acid Microspheres The present invention provides a method for producing a controlled release microsphere with mean average size greater than 50 μm, comprising preparing a water-in-oil (w/o) emulsion comprising an inner aqueous layer containing a pharmaceutically effective amount of a bi... | 12/15/2011 |
| 20110305767 | Polymer Particles Prepared From Polymerisable Alkylene Glycol (Meth) Acrylate Monomers The invention provides polymer particles that are obtainable by a method selected from emulsion methods, diffusion methods and evaporation methods carried out in the presence of surface-engineering surfactant which is one or more polymer that displays a lower critical s... | 12/15/2011 |
| 20110300209 | MODIFIED RELEASE SOLID PHARMACEUTICAL COMPOSITIONS OF TRIMETAZIDINE AND PROCESS THEREOF There is provided a modified release solid pharmaceutical composition comprising Trimetazidine and polyethylene oxide, wherein the composition does not include any lubricant.... | 12/08/2011 |
| 20110300224 | TASTE MASKED DOSAGE FORM OF PHARMACEUTICALLY ACCEPTABLE SALT OF ESCITALOPRAM A taste masked dosage form of pharmaceutical acceptable salt of escitalopram comprising (a) resin complex of pharmaceutical acceptable salt of escitalopram and cationic exchange resin or adsorbing or coating non-pareil seeds or inert particles with a mixture of pharmace... | 12/08/2011 |
| 20110293731 | LOADING OF HYDROPHOBIC DRUGS INTO HYDROPHILIC POLYMER DELIVERY SYSTEMS A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst eff... | 12/01/2011 |
| 20110293729 | NOVEL COMPOSITION BASED ON GAMMA-HYDROXYBUTYRIC ACID The present invention relates to a granule of gamma-hydroxybutyric acid or of one of its pharmaceutically acceptable salts, characterized in that it comprises a solid core on which the gamma-hydroxybutyric acid or one of its salts is supported.... | 12/01/2011 |
| 20110293730 | Polylactide nanoparticles A drug targeting system for administering a pharmacologically active substance to the central nervous system of a mammal across the animal's blood brain barrier. The drug targeting system comprises nanoparticles made of poly(DL-lactide) and/or poly(DL-lactide-co-glycoli... | 12/01/2011 |
| 20110287099 | Sustained-release formulations of topiramate Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to releas... | 11/24/2011 |
| 20110280945 | NOVEL METHOD FOR THE PREPARATION OF GRANULATES OF ACTIVE CONSTITUENTS, AND GRANULATES AS OBTAINED The present invention relates to a method for preparing a granulate of at least two active principles, including a step of applying said active principles to a solid particulate medium by dusting, said active principles not being plant extracts.... | 11/17/2011 |
| 20110280946 | Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same To provide surface-treating agents that can provide excellent hydrophobicity to powder and can improve its rinsability, to provide surface-treated powders that are treated with the surface-treating agent, and to provide cosmetics that comprise the surface-treated powder... | 11/17/2011 |
| 20110274619 | BRAIN TUMOR TARGETING PEPTIDES AND METHODS A method of diagnosing and treating a human glioblastoma multiforme (GBM) brain tumor in a subject is disclosed. The method includes administering to the subject, an effective amount of composition having a peptide 12-20 amino acid residues in length and selected for it... | 11/10/2011 |
| 20110274755 | SUPPORTIVE TREATMENT OF LIVER DISEASE The invention provides a composition and method for treatment of a subject suffering from liver disease comprising the oral administration of a slow release formulation of diltiazem and thiamine.... | 11/10/2011 |
