...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Application No. | Application Title | Issue Date |
| 20120128767 | THERAPEUTIC CALCIUM PHOSPHATE PARTICLES AND METHODS OF MAKING AND USING SAME The present invention provides novel calcium phosphate nanoparticles suitable for efficient encapsulation of biologically active molecules. The invention further provides pharmaceutical compositions comprising these nanoparticles, as well as methods of making such nanop... | 05/24/2012 |
| 20120128771 | TIMED, PULSATILE RELEASE SYSTEMS A unit multiparticulate dosage form for delivering one or more basic, active pharmaceutical ingredients into the body in need of such medications to achieve target PK (pharmacokinetics) profiles is described. The dosage form comprises one or more multicoated drug partic... | 05/24/2012 |
| 20120128764 | CONTROLLED-RELEASE COMPOSITIONS COMPRISING A PROTON PUMP INHIBITOR The present invention relates to pharmaceutical compositions, and methods of preparing such compositions, comprising one or more populations of controlled-release particles comprising one or more proton pump inhibitors. The present invention also relates to pharmaceutic... | 05/24/2012 |
| 20120128778 | COMPOSITIONS AND METHODS FOR ONCE-DAILY ADMINISTRATION OF A TRILAYER OSMOTIC TABLET A trilayer osmotic tablet is described. The tablet includes a core, a semi-permeable membrane disposed generally around the core, and an orifice in the semi-permeable membrane in fluid communication with the core. The core includes first, second, and third layers. The f... | 05/24/2012 |
| 20120128592 | SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) COMPOUNDS AND METHODS OF THEIR PREPARATION A compound for detecting an analyte using Surface Enhanced Raman Spectroscopy (SERS) and a method of forming the compound is provided. The compound has Formula I: wherein W is selected from the group consisti... | 05/24/2012 |
| 20120128782 | Multicomponent Degradable Cationic Polymers Degradable polymers were synthesized that self-assemble with DNA to form particles that are effective for gene delivery. Small changes to polymer synthesis conditions, particle formulation conditions, and polymer structure provides significant changes to efficacy in a c... | 05/24/2012 |
| 20120129916 | CELL-TARGETING NANOPARTICLES COMPRISING POLYNUCLEOTIDE AGENTS AND USES THEREOF A method of generating a particle is disclosed, the particle being for delivery of a polynucleotide to a target cell. The method comprises (a) contacting the polynucleotide with a composition comprising cationic molecules, wherein the cationic molecules condense the pol... | 05/24/2012 |
| 20120128780 | NANOPARTICULATE BISPHOSPHONATE COMPOSITIONS Nanoparticulate bisphosphonate compositions, having an effective average particle size of less than 2000 nm, are described. The compositions are useful in treating bone resorption in a mammal.... | 05/24/2012 |
| 20120128777 | COMPOSITIONS CONTAINING LIPID MICRO- OR NANOPARTICLES FOR THE ENHANCEMENT OF THE DERMAL ACTION OF SOLID PARTICLES The invention is related to compositions which can be used as dermal formulations for supporting the skin to restore normal conditions in case of e.g. irritated skin, or to support medical therapy of skin with atopic dermatitis symptoms, atopic dermatitis, psoriasis or ... | 05/24/2012 |
| 20120128773 | DESFESOTERODINE IN THE FORM OF A TARTARIC ACID SALT The invention concerns desfesoterodine in the form of a tartaric acid salt, in particular in the polymorphic “R form”, as well as a process for its production. In a second aspect, the invention concerns the desfesoterodine of the invention in a microencapsulated for... | 05/24/2012 |
| 20120107393 | Pellets for Delivery of Biologically Active Substances Pellets are made by combining a direct compression binder and a waxy spheronizing agent. The pellets may further contain additional pharmaceutical ingredients and/or a drug. The pellets may be compressed to form tablets or loaded into a capsule shell for oral administra... | 05/03/2012 |
| 20120109045 | Encapsulation of Microbubbles Within the Aqueous Core of Microcapsules The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsu... | 05/03/2012 |
| 20120107406 | Dry Powder Formulations A dry powder suitable for inhalation n a dry powder inhaler, the powder comprising a carrier, an active agent and at least 0.5% by weight of magnesium stearate, the powder being further characterized in that the less than 10% of the surface of the carrier material is co... | 05/03/2012 |
| 20120107380 | METHODS OF SAPONIFYING XANTHOPHYLL ESTERS AND ISOLATING XANTHOPHYLLS This invention relates to a practical and effective process for converting esterified xanthophylls, including zeaxanthin, to non-esterified xanthophylls through saponification. In addition, the invention provides a process for obtaining esterified zeaxanthin in high yie... | 05/03/2012 |
| 20120107407 | BONE GRAFT AND BIOCOMPOSITE FOR PROSTHETIC DENTISTRY A bone graft or biocomposite for treating osseous defects and neogenesis of bone which is a composite of a biodegradable polymer and granules of beta-tricalciumphosphate, further comprising as active ingredient and embedded in the biodegradable polymer a physiologically... | 05/03/2012 |
| 20120107405 | METHOD FOR THE DRY DISPERSION OF NANOPARTICLES AND THE PRODUCTION OF HIERARCHICAL STRUCTURES AND COATINGS The invention relates to a method for the dispersion of synthetic or natural nanoparticles and nanocomposite materials and to the use thereof in different sectors including those of ceramics, coatings, polymers, construction, paints, catalysis, pharmaceuticals and powde... | 05/03/2012 |
| 20120109044 | PREVENTION OF MYOCARDIAL INFRACTION INDUCED VENTRICULAR EXPANSION AND REMODELING A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart having a pathological condition. The method includes identifying a target region of the myocardium and applying material directly and substantially only to at least a portion... | 05/03/2012 |
| 20120082729 | QUICK DISSOLVE COMPOSITIONS AND TABLETS BASED THEREON The invention provides a composition useful for making oral dosage forms capable of dissolving in the mouth in less than 40 seconds without the need for a conventional super disintegrant and having a friability of less than 1%; wherein the composition includes liquiflas... | 04/05/2012 |
| 20120082718 | Morphine Formulations Described is a pellet composition comprising a core element comprising morphine sulfate, a filler and a binder, wherein the morphine sulfate, calculated as the anhydrous form, comprises about 50 wt % to about 85 wt % of the total weight of the core element; and a coatin... | 04/05/2012 |
| 20120082727 | USE OF MAGNESIUM STEARATE IN DRY POWDER FORMULATIONS FOR INHALATION Addition of magnesium stearate to a powder formulation for inhalation comprising carrier particles and an active ingredient bearing a group susceptible to hydrolysis is useful for inhibiting or reducing the chemical degradation of the active ingredient.... | 04/05/2012 |
| 20120070376 | YEAST CELL WALL PARTICLES FOR RECEPTOR-TARGETED NANOPARTICLE DELIVERY The present invention generally relates to yeast cell wall microparticles loaded with nanoparticles for receptor-targeted nanoparticle delivery. In particular, the present invention relates to trapping nanoparticles either on the surface or inside a yeast glucan particl... | 03/22/2012 |
| 20120070494 | Treatment for Attention-Deficit Hyperactivity Disorder A method for treating Attention Deficit/Hyperactivity Disorder (ADHD) in humans and the symptoms associated therewith, inattentiveness, and hyperactivity with impulsivity, using eltoprazine and related compounds is provided.... | 03/22/2012 |
| 20120070499 | DELAYED-RELEASE GLUCOCORTICOID TREATMENT OF RHEUMATOID DISEASE The present invention refers to the treatment of a rheumatic disease and/or osteoarthritis by administering a delayed-release dosage form of a glucocorticoid to a subject in need thereof.... | 03/22/2012 |
| 20120070503 | Nanoparticle-Based Targeted Drug Delivery For In Vivo Bone Loss Mitigation The present invention is directed to nanoparticle-based targeted drug delivery system for treatment of bone-loss. An enantiomeric phenothiazine is formulated into an in-vivo nanoparticle delivery system which may contain bone-targeting functionality. The nanoparticle fo... | 03/22/2012 |
| 20120070504 | PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF THE SYMPTOMS OF ADDICTION AND METHOD OF DIAGNOSING SAME A therapeutic agent for the treatment of the symptoms of addiction and the method for preparing the therapeutic agent is disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive/pancreatic enzymes. The therapeutic... | 03/22/2012 |
| 20120070501 | Method and Formulation for Treating Resistance to Antihypertensives and Related Conditions A method for the prevention or treatment of symptoms of hypertension in a patient who is resistant to antihypertensive effects of an antihypertensive compound administered in the absence of melatonin comprises administering to said patient melatonin in an amount effecti... | 03/22/2012 |
| 20120070500 | Nanoparticles Of Cerium Oxide Targeted To An Amyloid-Beta Antigen Of Alzheimer's Disease And Associated Methods Disclosed is a composition immunologically targeted to Alzheimer's disease (AD), the composition containing amine functionalized nanoparticles of Cerium oxide coated with polyethylene glycol and bearing an antibody specific for an amyloid-beta antigen associated with AD... | 03/22/2012 |
| 20120052127 | EXPANDED POLYSTYRENE PARTICLES HAVING SKIN LAYER WITH SUPERIOR MOLDABILITY, METHOD FOR PREPARING THE SAME AND EXPANDED POLYSTYRENE MOLDED ARTICLE USING THE SAME Disclosed are an expanded polystyrene particle having a skin layer with superior moldability, a method for preparing the same, and an expanded polystyrene molded article using the same. Provided is an expanded polystyrene particle provided on the surface thereof with a ... | 03/01/2012 |
| 20120053051 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A1, A2 and A3 are independently selected from the group consisting of CR3 and N; B1 B2 03/01/2012 | |
| 20120052125 | Cholesteryl Sulfate-Containing Composition As A Haemostatic The present invention relates to a composition comprising a wound dressing device and cholesteryl sulfate and especially to a composition containing cholesteryl sulfate and at least one carrier material for use as a haemostatic agent, as well as to a method for its prep... | 03/01/2012 |
| 20120052006 | GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF The present disclosure is directed generally to gold/lanthanide nanoparticle conjugates, such as gold/gadolinium nanoparticle conjugates, nanoparticle conjugates including polymers, nanoparticle conjugates conjugated to targeting agents and therapeutic agents, and their... | 03/01/2012 |
| 20120052126 | Nanoemulsions Containing Antioxidants And Other Health-Promoting Compounds Nanoemulsions contain particles that comprise an outer shell layer containing at least one oil and a core portion containing at least one antioxidant and, optionally, other health-promoting compounds, wherein the nanoemulsions are relatively stable for prolonged periods... | 03/01/2012 |
| 20120040008 | PHARMACEUTICAL COMPOSITIONS OF METABOTROPIC GLUTAMATE 5 RECEPTOR (MGLU5) ANTAGONISTS Pharmaceutical compositions of metabotropic glutamate 5 receptor (mGlu5) antagonists or a pharmacologically acceptable salt thereof are disclosed. The compositions contain the therapeutic active compound with non-ionic polymer and ionic polymer, binder and fillers in ei... | 02/16/2012 |
| 20120040009 | PARTICULATE PHARMACEUTICAL COMPOSITION WITH AN OPIOID AND AN OPIOID ANTAGONIST The invention relates to a pharmaceutical composition comprising first particles and second particles, the first particles comprising at least one opioid or a pharmaceutically acceptable salt thereof, and the second particles comprising at least one opioid antagonist or... | 02/16/2012 |
| 20120040000 | PEPTIDE PHARMACEUTICAL FOR ORAL DELIVERY Acid-containing oral pharmaceutical compositions are provided wherein the pharmaceutical active agents are peptide compounds (i.e., those that include a plurality of amino acids and at least one peptide bond in their molecular structures). Certain barrier layers and/or ... | 02/16/2012 |
| 20120040005 | NANOSTRUCTURED CALCIUM-SILVER PHOSPHATE COMPOSITE POWDERS, PROCESS FOR OBTAINING THE POWDERS, AND BACTERICIDAL AND FUNGICIDAL APPLICATIONS THEREOF Described in example embodiments are nanocomposite powders including calcium phosphate and silver nanoparticles on the surface of the calcium phosphate. Other example embodiments, describe methods of forming nanocomposite powders comprising a) preparing a nanometric cal... | 02/16/2012 |
| 20120039978 | Novel Anti-Viral Method The invention provides a method of reducing viral infectivity in a sample compnsing contacting the sample with a earner matrix wherein lipids are attached to the carrier matrix, and wherein at least one virus-specific agent is attached to the lipids The virus-specific a... | 02/16/2012 |
| 20120040007 | SERINE PALMITOYLTRANSFERASE INHIBITORS FOR PREVENTING AND DELAYING RETINITIS PIGMENTOSA The method for preventing and delaying inherited retinal degenerations using serine palmitoyltransferase inhibitors, and compositions which contain them.... | 02/16/2012 |
| 20120040006 | Pharmaceutical Compositions Comprising Brivaracetam The present invention relates to a pharmaceutical composition comprising brivaracetam as active ingredient, the invention relates specifically to a prolonged release formulation.... | 02/16/2012 |
| 20120034300 | STABILIZED ZOLPIDEM PHARMACEUTICAL COMPOSITIONS Methods of inducing antinociception in a human are described. The method includes the step of administering an effective dose of a polypeptide comprising L-neo-tryptophan to the human extracranially. The polypeptide containing L-neo-tryptophan could be, but is not limit... | 02/09/2012 |