...that it was melting ice cream that inspired the invention of the outboard motor? It was a lovely August day and Ole Evinrude was rowing his boat to his favorite island picnic spot. As he rowed, he watched his ice cream melt and wished he had a faster way to get to the island. At that moment the idea for the outboard motor was born!
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| Application No. | Application Title | Issue Date |
| 20120130300 | Therapeutic Methods Using Controlled Delivery Devices Having Zero Order Kinetics An injectable or implantable medical device having orifice(s) on the surface that release an active agent with zero-order release kinetics is described herein. The device is a hollow matrix of any size or shape, which can be made from both metal and non-metal surfaces. ... | 05/24/2012 |
| 20120107383 | OSTEOCONDUCTIVE MATRICES COMPRISING CALCIUM PHOSPHATE PARTICLES AND STATINS AND METHODS OF USING THE SAME Osteoconductive matrices and methods are provided that have one or more statins disposed in calcium phosphate particles. The matrices may be injected into a fracture site. The osteoconductive matrices provided allow for sustained release of the statin and facilitate bon... | 05/03/2012 |
| 20120067361 | PLANT FIBER PRODUCT AND METHOD FOR ITS MANUFACTURE The disclosure relates to a plant fiber product for oral use, the product containing a mixture of at least: plant fibers; and at least one added substance intended to be released from the product when the product is used. The product contains an alginate composition, di... | 03/22/2012 |
| 20120053619 | HEMOSTATIC COMPOSITIONS AND METHODS OF MAKING AND USING SAME The disclosure pertains to hemostatic compositions comprising a plurality of nonwoven fibers disposed in a rapidly soluble solid matrix and methods of making and using the same. The compositions may also comprise one or more therapeutic agents.... | 03/01/2012 |
| 20120034307 | Aqueous gel formulation and method for inducing topical anesthesia Disclosed is a stable aqueous gel formulation suitable for topical use comprising water, an anesthetic (e.g., lidocaine hydrochloride), a viscoelastic polymer, and a tonicity modifier, wherein the aqueous gel formulation is free of preservatives and phosphate buffer, is... | 02/09/2012 |
| 20120021052 | CONTROLLED RELEASE AND TASTE MASKING ORAL PHARMACEUTICAL COMPOSITION Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophili... | 01/26/2012 |
| 20120021053 | CONTROLLED RELEASE AND TASTE-MASKING ORAL PHARMACEUTICAL COMPOSITION Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophili... | 01/26/2012 |
| 20120009263 | GRANULAR DELIVERY SYSTEM A granular delivery system and a method of preparing the same by creating a melt emulsion having a continuous phase and a dispersed active, wherein the continuous phase includes trehalose and a hydrogenated starch hydrolysate having number average degree of polymerizati... | 01/12/2012 |
| 20120003316 | TRANSMUCOSAL DELIVERY SYSTEM This invention relates to a multi-configured, transmucosal pharmaceutical dosage form and, more particularly, to a pharmaceutical dosage form which has a single monolithic/heterogeneous layer or a plurality of such layers. The dosage form is suitable for the delivery of... | 01/05/2012 |
| 20110318413 | EXTENDED RELEASE FORMULATIONS CONTAINING DARIFENACIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF The present invention relates to an extended release formulation comprising darifenacin or pharmaceutically acceptable salts thereof and one or more release controlling hydrophobic materials optionally coated with combination of one or more release controlling hydrophob... | 12/29/2011 |
| 20110318416 | BIORESORBABLE POLYMER MATRICES AND METHODS OF MAKING AND USING THE SAME A bioerodible composition for delivery of a bioactive agent is the reaction product of a reaction mixture which includes an oxidized dextran solution, and a mixture of solids containing a dihydrazide, a bioactive agent, and optionally a pH adjusting agent in an amount s... | 12/29/2011 |
| 20110311632 | STABLE CHITOSAN HEMOSTATIC EXTERNAL PATCH AND METHODS OF MANUFACTURE Hemostatic products with improved stability are prepared from crosslinked chitosan hemostatic compositions. The crosslinked chitosan hemostatic compositions have improved stability and can be prepared into a variety of medical devices in various shapes and sizes so as t... | 12/22/2011 |
| 20110311608 | STABLE CHITOSAN HEMOSTATIC IMPLANT AND METHODS OF MANUFACTURE Implantable hemostatic products with improved stability are prepared from crosslinked chitosan hemostatic compositions. The crosslinked chitosan hemostatic compositions have improved stability and can be prepared into a variety of implantable medical devices in various ... | 12/22/2011 |
| 20110293720 | PROGESTIN-CONTAINING DRUG DELIVERY SYSTEM The present invention relates to drug delivery compositions in the form of thin water-soluble films (wafers), which contain small particles that comprise at least one progestin and at least one protective agent. The protective agent provides effective taste-masking of t... | 12/01/2011 |
| 20110293722 | HYDROGEL SPONGES, METHODS OF PRODUCING THEM AND USES THEREOF A macroporous hydrogel sponge is provided selected from: (i) a synthetic polymer hydrogel sponge, and (ii) a synthetic polymer-polypeptide conjugate hydrogel sponge, the macroporous hydrogel sponge being at least 20% porous and having a pore diameter of 50-1000 μm, whe... | 12/01/2011 |
| 20110274756 | METHOD AND MEMBRANE FOR TISSUE REGENERATION Tissue regeneration or grafting is promoted utilizing a structure including a multi-layer sheet of collagen membrane material which includes a purified collagen barrier sheet material derived from natural collagen-containing tissue, the barrier sheet material including ... | 11/10/2011 |
| 20110250257 | FIBROUS TISSUE SEALANT AND METHOD OF USING SAME Disclosed herein is a fibrous tissue sealant in the form of an anhydrous fibrous sheet comprising a first component which is a fibrous polymer containing electrophilic or nucleophilic groups and a second component capable of crosslinking the first component when the she... | 10/13/2011 |
| 20110250267 | USE OF DIINDOLYLMETHANE-RELATED INDOLES FOR THE TREATMENT AND PREVENTION OF RESPIRATORY SYNCYTIAL VIRUS ASSOCIATED CONDITIONS The present invention includes compositions and methods for the treatment and prevention of conditions associated with Respiratory Syncytial Virus (RSV) infection. RSV-associated conditions include acute infections in mammals, typically bronchiolitis and pneumonia, and ... | 10/13/2011 |
| 20110244032 | DISPERSIBLE PHOSPHOLIPID STABILIZED MICROPARTICLES Rapidly dispersing solid dry therapeutic dosage form comprised of a water insoluble compound existing as a nanometer or micrometer particulate solid which is surface stabilized by the presence of at least one phospholipid, the particulate solid being dispersed throughou... | 10/06/2011 |
| 20110244045 | CONTROLLED RELEASE OF N-ACETYLCYSTEINE (NAC) FOR REDUCTION OF SYSTEMIC AND/OR VASCULAR INFLAMMATION The present invention provides a controlled-release composition which provides a therapeutically effective plasma concentration of N-acetylcysteine over prolonged period of time. The present invention also includes the use of the controlled-release composition, either a... | 10/06/2011 |
| 20110236454 | INJECTABLE DRUG DELIVERY FORMULATION The invention provides an injectable formulation that includes an active agent; a biocompatible solvent system, crosslinkable polymers such as polysaccharides; and crosslinking agents; wherein the formulation is substantially free of water. The invention also provides a... | 09/29/2011 |
| 20110236486 | METHOD TO PRODUCE HYALURONIC ACID FUNCTIONALIZED DERIVATIVES AND FORMATION OF HYDROGELS THEREOF A system and method are provided for controlling an internal combustion engine driving a generator/welder or a stand-alone generator. Controlling the engine may include altering the engine speed based upon a detected demand on the generator and/or operating parameters o... | 09/29/2011 |
| 20110230816 | Gels for Transdermal Delivery The present disclosure provides hydrogels that are suitable for drug delivery. In embodiments, hydrogels of the present disclosure may be used for transdermal delivery of bioactive agents, including drugs. The hydrogels of the present disclosure may also be useful as co... | 09/22/2011 |
| 20110229574 | POLYSACCHARIDE AND PROTEIN-POLYSACCHARIDE CROSS-LINKED HYDROGELS FOR SOFT TISSUE AUGMENTATION Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and optionally including proteins. In one aspect, hyaluronic acid-based compositions described herein include zero-length cross-linked moieties and op... | 09/22/2011 |
| 20110229573 | PROCESS OF MANUFACTURING A LYOPHILIZED FAST DISSOLVING, MULTI-PHASIC DOSAGE FORM A multi-phasic, lyophilized, fast-dissolving dosage form (FDDF) for the delivery of a pharmaceutically active ingredient is prepared by sequential dosing of a formulation containing a non-gelling matrix forming agent and a formulation containing a gelling gelatin.... | 09/22/2011 |
| 20110223242 | NANOPARTICLES CONTAINING A PEPTIDE, VECTORS CONTAINING SAID NANOPARTICLES, AND PHARMACEUTICAL USES OF SAID NANOPARTICLES AND VECTORS The invention relates to nanoparticles comprising a matrix containing at least one polysaccharide as well as the peptide P140 having the sequence SEQ ID NO: 1 or an analog thereof, said polysaccharide preferably being a polysaccharide bearing one or more negatively-char... | 09/15/2011 |
| 20110212173 | Controlled Release Treatment of Depression There is described a pharmaceutical composition for controlled release of an active compound wherein the active compound is selected from the group comprising tramadol, resveratrol, acetaminophen, xorphanol, cinfenoac, furcloprofen, bismuth subsalicylate, enofelast, tri... | 09/01/2011 |
| 20110206769 | ORAL ANTIDEPRESSANT FORMULATION WITH REDUCED EXCIPIENT LOAD Provided are methods for reducing the excipient load of pharmaceutical formulations containing 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide as the active pharmaceutical ingredient, and compositions related thereto. In particular, provided is a pharmaceut... | 08/25/2011 |
| 20110200655 | Systems and methods that kill infectious agents (bacteria) without the use of a systemic anti-biotic A medical product is provided that is selected from at least one of, nasal cannulas, oxygen masks, wound dressings, bandages, band aids, catheters, endotrachial tubes, condoms, surgical and other gloves, sheaths for endoscopy probes, and medical products that physically... | 08/18/2011 |
| 20110200676 | CROSS-LINKED OXIDATED HYALURONIC ACID FOR USE AS A VITREOUS SUBSTITUTE A composition comprising a polymer that comprises oxidated hyaluronic acid cross-linked by a dihydrazide is disclosed. The polymer is a hydrogel exhibiting the following properties: a) transparent and colorless; and b) transforming from a liquid state into a gel-matrix ... | 08/18/2011 |
| 20110190688 | Permeant Delivery System and Methods for Use Thereof Disclosed are a patch, system, and method for delivery of a permeant composition into a subject via at least one formed pathway through a biological membrane of the subject. The patch comprises a matrix, at least one hydrophilic permeant disposed within the matrix, wher... | 08/04/2011 |
| 20110189292 | DERMAL FILLERS COMPRISING SILK FIBROIN HYDROGELS AND USES THEREOF The present specification provides compositions useful as dermal fillers and methods using such compositions to treat a condition of skin.... | 08/04/2011 |
| 20110171311 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES The present specification generally relates to hydrogel compositions and methods of treating a soft tissue condition using such hydrogel compositions.... | 07/14/2011 |
| 20110171308 | PH-SENSITIVE SOLID PHARMACEUTICAL COMPOSITION FOR ORAL PREPARATION AND PREPARATION METHOD THEREOF A pH-sensitive solid pharmaceutical composition for oral formulation and preparation method thereof is provided. The solid pharmaceutical composition contains a pharmaceutical active ingredient, a nano-matrix carrier and a pH-sensitive polymer material.... | 07/14/2011 |
| 20110171310 | HYDROGEL COMPOSITIONS COMPRISING VASOCONSTRICTING AND ANTI-HEMORRHAGIC AGENTS FOR DERMATOLOGICAL USE The present specification generally relates to hydrogel compositions and methods of treating a soft tissue condition using such hydrogel compositions.... | 07/14/2011 |
| 20110165249 | PHARMACEUTICAL SOLID PREPARATION An object of the present invention is to provide a gradual disintegration-type, sustained-release pharmaceutical solid preparation whose pharmacologically active substance release behavior is controlled. The solid pharmaceutical preparation of the present invention is a... | 07/07/2011 |
| 20110150993 | Fine Particle Croscarmellose and Uses Thereof The disclosure is directed to fine particle croscarmellose and its use in various compositions such as solid dosage forms. More specifically, the present disclosure relates to fine particle croscarmellose having a median particle size of 5 μm to 36 μm and a volume mea... | 06/23/2011 |
| 20110150994 | Modified Release Formulation The invention is directed to the use of an extended release tablet formulation for pramipexole.... | 06/23/2011 |
| 20110151005 | METHODS AND MEANS FOR SOFT TISSUE ENGINEERING Cellfree adipose tissue extracts, implants including the same and methods for the preparation thereof. The extracts and implants are capable of inducing adipogenesis and angiogenesis and are, thus, useful in applications including soft tissue repair and engineering and ... | 06/23/2011 |
| 20110142939 | Use of a Combination of an Opioid Agonist and an Opioid Antagonist for the Treatment of Crohn's Disease and the Symptoms Associated with Crohn's Disease The present invention is concerned with the use of combinations of opioid agonists and antagonists for treating Crohn's disease.... | 06/16/2011 |