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| Application No. | Application Title | Issue Date |
| 20120130300 | Therapeutic Methods Using Controlled Delivery Devices Having Zero Order Kinetics An injectable or implantable medical device having orifice(s) on the surface that release an active agent with zero-order release kinetics is described herein. The device is a hollow matrix of any size or shape, which can be made from both metal and non-metal surfaces. ... | 05/24/2012 |
| 20120107404 | Crystalline Pharmaceutical and Methods of Preparation and Use Thereof Novel crystalline polymorphic forms, Forms A, B, C, D, and E of a compound of Formula I, which has been found to be a potent inhibitor of LFA-1, are disclosed. Methods of preparation and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed in this... | 05/03/2012 |
| 20120107394 | IMMUNO-COMPATIBLE HYDROGEL SYSTEM An immuno-compatible hydrogel system is provided that is resistant to protein binding. The hydrogel system is prepared by contacting a hydrogel solution with a cross-linking agent to form a gel, exposing the gel to an aqueous solution comprising a first polyelectrolyte ... | 05/03/2012 |
| 20120107383 | OSTEOCONDUCTIVE MATRICES COMPRISING CALCIUM PHOSPHATE PARTICLES AND STATINS AND METHODS OF USING THE SAME Osteoconductive matrices and methods are provided that have one or more statins disposed in calcium phosphate particles. The matrices may be injected into a fracture site. The osteoconductive matrices provided allow for sustained release of the statin and facilitate bon... | 05/03/2012 |
| 20120071967 | ONE-STEP PHOSPHORYLCHOLINE-LINKED POLYMER COATING AND DRUG LOADING OF STENT A one step method for drug coating an interventional device is disclosed by mixing a drug with a phosphorylcholine-linked methacrylate polymer in a liquid and applying the mixture to an interventional device, such as a stent, in a single step.... | 03/22/2012 |
| 20120052123 | SILYL ETHER-MODIFIED HYDROPHILIC POLYMERS AND USES FOR MEDICAL ARTICLES Silane-functionalized hydrophilic polymers and polymeric matrices are described. Hydrophilic matrices can be formed from the polymers, and can be used in association with the preparation of implantable and injectable medical devices. Exemplary devices include those havi... | 03/01/2012 |
| 20120045513 | POLYMER-BASED, SUSTAINED RELEASE DRUG DELIVERY SYSTEM Disclosed is a sustained release system that includes a polymer and a pharmaceutically active agent dispersed in the polymer. The agent is in granular or particulate form, and has a rate of release from the system that is limited primarily by the rate at which the agent... | 02/23/2012 |
| 20120039975 | NANOCOMPOSITE MATERIALS HAVING ELECTROMAGNETIC-RADIATION BARRIER PROPERTIES AND PROCESS FOR OBTAINMENT THEREOF Nanocomposite materials having electromagnetic-radiation barrier properties comprising layered nanoadditives with or without organic and/or inorganic surface modification; and a polymeric matrix, process for obtainment thereof and use of said nanocomposite materials in ... | 02/16/2012 |
| 20120040002 | RESORBABLE AND BIOCOMPATIBLE FIBRE GLASS COMPOSITIONS AND THEIR USES Biocompatible and resorbable melt derived glass compositions which include: SiO2 60-70 weight-%, Na2O 5-20 weight-%, CaO 5-25 weight-%, MgO 0-10 weight-%, P2O5 0.5-3.0 weight-%, B2O3 0-15 weight-%, Al 02/16/2012 | |
| 20120034306 | POLYMERIC DRUG DELIVERY SYSTEMS AND PROCESSES FOR PRODUCING SUCH SYSTEMS The subject invention relates to implants for delivery of therapeutic agents such as opioids, and the manufacture and uses of such implants.... | 02/09/2012 |
| 20120034305 | SOLID DISPERSING VACCINE COMPOSITION FOR ORAL DELIVERY The invention disclosed herein relate to an oral vaccine in which the vaccine composition and adjuvant(s) are carried on a solid fast-dispersing dosage form. The vaccines are targeted toward mucosal tissue and the adjuvant serves to ensure sufficient residence time for ... | 02/09/2012 |
| 20120021053 | CONTROLLED RELEASE AND TASTE-MASKING ORAL PHARMACEUTICAL COMPOSITION Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophili... | 01/26/2012 |
| 20120021052 | CONTROLLED RELEASE AND TASTE MASKING ORAL PHARMACEUTICAL COMPOSITION Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophili... | 01/26/2012 |
| 20120009262 | MEDICAL APPARATUS AND METHOD FOR PRODUCING SAME A medical device that includes at least one antibiotic in a macromolecular substance that swells upon contact with a solvent. Also, a method for preparing an antibiotic-containing medical device that involves contacting a medical device having at least a portion of the ... | 01/12/2012 |
| 20120003316 | TRANSMUCOSAL DELIVERY SYSTEM This invention relates to a multi-configured, transmucosal pharmaceutical dosage form and, more particularly, to a pharmaceutical dosage form which has a single monolithic/heterogeneous layer or a plurality of such layers. The dosage form is suitable for the delivery of... | 01/05/2012 |
| 20110318415 | Hollow Gold Nanospheres (HAuNSs) and HAuNSs-Loaded Microspheres Useful in Drug Delivery A near-infrared mediated drug delivery system comprising a plurality of microspheres made of polymeric material, each sphere containing a plurality of hollow gold nanospheres together with drug product, wherein upon NIR irradiation, the drug product is released from the... | 12/29/2011 |
| 20110311631 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION WITH RESISTANCE AGAINST THE INFLUENCE OF ETHANOL EMPLOYING A COATING COMPRISING A POLYMER MIXTURE AND EXCIPIENTS The invention relates to a controlled release pharmaceutical composition, comprising a core, comprising a pharmaceutical active ingredient, whereby the core is coated by an ethanol resistance conferring coating layer which has the effect of conferring the release profil... | 12/22/2011 |
| 20110311630 | Novel embedment particles for inhalation The invention relates to the preparation of inhalable powders which exhibit a delayed release of active substance and processes for preparing them as well as medicaments that can be produced using these inhalable powders.... | 12/22/2011 |
| 20110293720 | PROGESTIN-CONTAINING DRUG DELIVERY SYSTEM The present invention relates to drug delivery compositions in the form of thin water-soluble films (wafers), which contain small particles that comprise at least one progestin and at least one protective agent. The protective agent provides effective taste-masking of t... | 12/01/2011 |
| 20110293721 | PIROXICAM-CONTAINING MATRIX PATCHES AND METHODS FOR THE TOPICAL TREATMENT OF ACUTE AND CHRONIC PAIN AND INFLAMMATION THEREWITH This invention relates to matrix patches for the topical (i.e., transdermal) delivery of piroxicam and methods for the treatment of acute and chronic pain and inflammation therewith, particularly pain and inflammation caused by sports injuries or other muscle aches or i... | 12/01/2011 |
| 20110256201 | HYDROLYZED HYDROGELS The invention provides methods of making hydrolyzed cross-linked polyvinyl alcohol (PVA) hydrogels by polymerizing vinyl acetate (VAc) monomers to polyvinyl acetate (PVAc) polymer network by chemical-crosslinking and hydrolysis. The invention also provides methods for i... | 10/20/2011 |
| 20110250257 | FIBROUS TISSUE SEALANT AND METHOD OF USING SAME Disclosed herein is a fibrous tissue sealant in the form of an anhydrous fibrous sheet comprising a first component which is a fibrous polymer containing electrophilic or nucleophilic groups and a second component capable of crosslinking the first component when the she... | 10/13/2011 |
| 20110243848 | STAR POLYMERS, METHODS OF PREPARATION THEREOF, AND USES THEREOF A composition of matter comprising an amphiphilic star polymer, the star polymer comprising a crosslinked microgel core and 6 or more independent polymer arms covalently linked to the core, the 6 or more arms each comprising a hydrophilic polymer chain segment and a hyd... | 10/06/2011 |
| 20110244010 | Medical devices including medicaments and methods of making and using same The present invention recognizes that medical devices, such as but not limited to contact lenses, can be made having a coating made at least in part using printing technologies to provide drug storage and drug release structures. The coating preferably includes at least... | 10/06/2011 |
| 20110238036 | SUSTAINED RELEASE DELIVERY DEVICES An injectable drug delivery device includes a core containing one or more drugs and one or more polymers. The core may be surrounded by one or more polymer outer layers (referred to herein as “coatings,” “skins,” or “outer layers”). In certain embodiments, t... | 09/29/2011 |
| 20110236454 | INJECTABLE DRUG DELIVERY FORMULATION The invention provides an injectable formulation that includes an active agent; a biocompatible solvent system, crosslinkable polymers such as polysaccharides; and crosslinking agents; wherein the formulation is substantially free of water. The invention also provides a... | 09/29/2011 |
| 20110236485 | SHELL AND CORE DOSAGE FORM APPROACHING ZERO-ORDER DRUG RELEASE Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gas... | 09/29/2011 |
| 20110230816 | Gels for Transdermal Delivery The present disclosure provides hydrogels that are suitable for drug delivery. In embodiments, hydrogels of the present disclosure may be used for transdermal delivery of bioactive agents, including drugs. The hydrogels of the present disclosure may also be useful as co... | 09/22/2011 |
| 20110229572 | DELIVERY OF DRUG COMBINATIONS A composition comprising microspheres of a polymer matrix, having two different pharmaceutical actives having complementary, usually synergistic, activity in killing cells. The compositions have particular utility for treating tumours. Useful combinations are doxorubici... | 09/22/2011 |
| 20110223254 | FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM The present invention relates to dephenolic compounds, an example of which is shown below, which are functionalized, and polymers formed from the same. Polymers formed from the functionalized diphenolics are ... | 09/15/2011 |
| 20110217379 | MAGNETIC NANOMATERIALS AND METHODS FOR CHEMOEMBOLISATION There are disclosed magnetic nanoparticles and embolisation compositions comprising the nanoparticles. There are also disclosed methods to make the nanoparticles and embolisation compositions and methods to deliver therapeutic agents to a subject.... | 09/08/2011 |
| 20110217371 | CONTROLLED-RELEASE MICROPARTICLES AND METHOD OF PREPARING SAME Disclosed is a controlled-release microparticle: including a matrix comprising a pharmacologically active component; and a controlled-release layer comprising a substance which forms a controlled-release stratum on the matrix. The disclosed controlled-release microparti... | 09/08/2011 |
| 20110212178 | Injectable Hydrogel Filaments For Biomedical Uses Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations with radiopaque hydrogel filaments with delayed controlled rates of expansion permitting the repositioning of the device once inside the structure or mal... | 09/01/2011 |
| 20110200675 | DRUG DELIVERY VEHICLES, METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF Drug delivery vehicles that release one or more drugs, e.g., an opioid antagonist and/or an opioid, in response to changes in the chemistry of body fluids, specifically in response to changes in the partial pressure of CO2 in the environment of the hydrogel a... | 08/18/2011 |
| 20110200674 | ANTIMICROBIAL FOAM AND METHOD OF MANUFACTURE An antimicrobial foam includes an open-cell foam in a foam matrix defining a plurality of interconnected bubbles therein. Silver nanoparticles are suspended within the foam matrix. The foam matrix may be made from polyether polyurethane, polyester polyurethane, polycarb... | 08/18/2011 |
| 20110196502 | Methods of Using Water-Soluble Inorganic Compounds for Implants A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-s... | 08/11/2011 |
| 20110195124 | PHASE-TRANSITION POLYMERIC MICRONEEDLES This invention discloses a novel microneedle system, phase-transition microneedle patch, which overcomes all the limitations that existing microneedles encountered. The microneedle patch is formed of an integrated polymeric piece consisting of a microneedle array and a ... | 08/11/2011 |
| 20110189291 | DENDRIMER HYDROGELS Photoactivatable dendrimers and hydrogels formed therefrom include dendrimers to which polymer chains (e.g. polyethylene glycol, PEG) have been conjugated; and reactive photoactivatable groups attached to terminal functional groups of the polymer chains (e.g. hydroxyls ... | 08/04/2011 |
| 20110165248 | PHARMACEUTICAL DOSAGE FORMS COMPRISING POLY(E-CAPROLACTONE) The present invention relates to pharmaceutical dosage forms, for example to pharmaceutical dosage forms comprising poly(ε-caprolactone), and processes of manufacture, uses, and methods of treatment thereof.... | 07/07/2011 |
| 20110165246 | SILICONE ELASTOMER PRODUCT EXHIBITING A BIOCIDAL ACTIVITY The present invention relates to an antimicrobial product obtained from a silicone-based system exhibiting a biocidal activity on its surface, said system comprising a silicone elastomer matrix and a mineral filler of particles chosen from the group of the silicas or al... | 07/07/2011 |
