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| Application No. | Application Title | Issue Date |
| 20120128774 | MAXILLOFACIAL BONE AUGMENTATION USING RHPDGF-BB AND A BIOCOMPATIBLE MATRIX The present invention provides effective new methods and materials for maxillofacial bone augmentation, particularly alveolar ridge augmentation, that are free of problems associated with prior art methods. In one embodiment, these materials include human recombinant pl... | 05/24/2012 |
| 20120130300 | Therapeutic Methods Using Controlled Delivery Devices Having Zero Order Kinetics An injectable or implantable medical device having orifice(s) on the surface that release an active agent with zero-order release kinetics is described herein. The device is a hollow matrix of any size or shape, which can be made from both metal and non-metal surfaces. ... | 05/24/2012 |
| 20120107402 | PROCESS FOR ANALYZING AND ESTABLISHING DOSAGE SIZE IN AN INGESTIBLE FILM The present invention is directed to a method of analyzing and establishing a proper dosage size in ingestible films for providing a more precise dosage delivery of an active ingredient.... | 05/03/2012 |
| 20120107403 | BLADDER RECONSTRUCTION The invention is directed to methods and devices for the reconstruction, repair, augmentation or replacement of laminarily organized luminal organs or tissue structures in a patient in need of such treatment. The device comprises a biocompatible synthetic or natural pol... | 05/03/2012 |
| 20120107401 | OSTEOCONDUCTIVE MATRICES COMPRISING STATINS AND METHODS OF USING THE SAME Osteoconductive matrices and methods are provided that have one or more statins disposed therein. The matrices may be injected into a fracture site. The osteoconductive matrices provided allow for sustain release of the statin and facilitate bone formation and repair of... | 05/03/2012 |
| 20120107383 | OSTEOCONDUCTIVE MATRICES COMPRISING CALCIUM PHOSPHATE PARTICLES AND STATINS AND METHODS OF USING THE SAME Osteoconductive matrices and methods are provided that have one or more statins disposed in calcium phosphate particles. The matrices may be injected into a fracture site. The osteoconductive matrices provided allow for sustained release of the statin and facilitate bon... | 05/03/2012 |
| 20120107404 | Crystalline Pharmaceutical and Methods of Preparation and Use Thereof Novel crystalline polymorphic forms, Forms A, B, C, D, and E of a compound of Formula I, which has been found to be a potent inhibitor of LFA-1, are disclosed. Methods of preparation and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed in this... | 05/03/2012 |
| 20120082724 | DRY MOULDABLE DRUG FORMULATION Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.... | 04/05/2012 |
| 20120082714 | TRANSDERMAL THERAPEUTIC SYSTEM WITH CRYSTALLIZATION-INHIBITING PROTECTIVE FILM (RELEASE LINER) The invention relates to pharmaceutical formulations, in particular to transdermal therapeutic systems, which are characterized in that little or no active ingredient crystallizes out at the interface between the removable protective film (release liner) and the active-... | 04/05/2012 |
| 20120071865 | FLOWABLE HYDROGELS FOR CONTROL OF CELL IN-MIGRATION Materials and methods of treating an eye with a hydrogel formed on the eye. Embodiments are provided that include post-keratectomy bandages.... | 03/22/2012 |
| 20120070483 | Multi-Functional Biocompatible Coatings for Intravascular Devices A polymeric coating is adapted to substantially eliminate thrombus formation when in contact with blood. The polymeric coating includes a first polymeric layer and a second polymeric layer. Interposed between the first and second polymeric layers is a polymeric matrix l... | 03/22/2012 |
| 20120070380 | Ingestible salt grabber Disclosed herein include embodiments related to compositions, devices, computer systems, computer-implemented methods, and computer program products associated with an ingestible salt grabber.... | 03/22/2012 |
| 20120053619 | HEMOSTATIC COMPOSITIONS AND METHODS OF MAKING AND USING SAME The disclosure pertains to hemostatic compositions comprising a plurality of nonwoven fibers disposed in a rapidly soluble solid matrix and methods of making and using the same. The compositions may also comprise one or more therapeutic agents.... | 03/01/2012 |
| 20120045512 | METHODS AND SUBSTRATES FOR DIFFERENTIATION OF NEURAL STEM CELLS The present invention is directed to methods and substrates for promoting the differentiation of neural stem cells to neurons.... | 02/23/2012 |
| 20120045511 | THERMOSENSITIVE HEPATITIS B VACCINE A thermosensitive hepatitis B vaccine is provided. The thermosensitive hepatitis B vaccine includes an aqueous phase solution comprising a biodegradable thermosensitive hydrogel copolymer; a surface antigen of hepatitis B virus (HBsAg); and a bioactive substance. The th... | 02/23/2012 |
| 20120045504 | ORAL DRUG DEVICES AND DRUG FORMULATIONS Compositions containing a drug to be delivered and at least one chemical permeation enhancer (CPE), and methods of making and using these compositions are described herein. In a preferred embodiment, the compositions contain two or more CPEs which behave in synergy to i... | 02/23/2012 |
| 20120040001 | DISINTEGRATING PARTICLE COMPOSITION AND RAPIDLY DISINTEGRATING COMPRESSION-MOLDED MATERIAL USED THE SAME [Subject Matter] A rapidly disintegrating compression-molded material has been demanded, which exhibits good taking feeling and taste in the oral cavity, has a sufficient hardness for prevent the material from causing problems such as crack... | 02/16/2012 |
| 20120040002 | RESORBABLE AND BIOCOMPATIBLE FIBRE GLASS COMPOSITIONS AND THEIR USES Biocompatible and resorbable melt derived glass compositions which include: SiO2 60-70 weight-%, Na2O 5-20 weight-%, CaO 5-25 weight-%, MgO 0-10 weight-%, P2O5 0.5-3.0 weight-%, B2O3 0-15 weight-%, Al 02/16/2012 | |
| 20120039796 | Novel method for creating, suspending and stabilizing electronically modified oxygen derivatives, along with creating, suspending and stabilizing electronically modified reaction intermediates, in a bio compatible fluorocarbon suspension, for the purpose of inducing a cascading immune response in mammalian patients A bio compatible free radical suspension, comprising of oxygen and electronically modified reaction intermediates, where a fluorocarbon is used as an inert medium for stabilization of reaction intermediates. A stabilized bio compatible electronically modified derivative... | 02/16/2012 |
| 20120034304 | Prolonged Release Pharmaceutical Composition Containing 3-(3-Dimethylamino-1-Ethyl-2-Methyl-Propyl)Phenol A pharmaceutical formulation for prolonged release of the active ingredient 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol or a pharmaceutically acceptable salt thereof in a matrix containing between 1 and 80 wt. % of at least one pharmaceutically acceptable hydrophil... | 02/09/2012 |
| 20120027858 | Methods and Compositions for Managing Cancer Cell Growth The invention relates to composition and a method of using the composition for modulating proliferation, invasiveness, the expression of a biomarker of an abnormal cell, of reducing the risk of a patient cell becoming abnormal, or of modulating proliferation of a carcin... | 02/02/2012 |
| 20120021052 | CONTROLLED RELEASE AND TASTE MASKING ORAL PHARMACEUTICAL COMPOSITION Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophili... | 01/26/2012 |
| 20120021053 | CONTROLLED RELEASE AND TASTE-MASKING ORAL PHARMACEUTICAL COMPOSITION Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophili... | 01/26/2012 |
| 20120009260 | NANOPARTICLE FILM DELIVERY SYSTEMS A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform a therapeutic or bioeffecting function.... | 01/12/2012 |
| 20120009261 | NOVEL GASTRO-RETENTIVE DOSAGE FORMS A gastro-retentive pharmaceutical dosage form of a therapeutically effective amount of at least one GABA Analog, at least one opioid, and at least one pharmaceutically acceptable excipient wherein the said dosage form is retained in the stomach for at least four hours a... | 01/12/2012 |
| 20120010599 | INORGANICALLY SURFACE-MODIFIED POLYMERS AND METHODS FOR MAKING AND USING THEM In alternative embodiments, the invention provides articles of manufacture comprising biocompatible nanostructures comprising PolyEther EtherKetone (PEEK) surface-modified (surface-nanopatterned) to exhibit nanostructured surfaces that promote osseointegration and bone-... | 01/12/2012 |
| 20120003315 | Flowable Carrier Matrix A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These pieces are sized so that, when wet, they are capable of flowing through a c... | 01/05/2012 |
| 20110318414 | REGENERATIVE TISSUE GRAFTS AND METHODS OF MAKING SAME A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested fro... | 12/29/2011 |
| 20110318413 | EXTENDED RELEASE FORMULATIONS CONTAINING DARIFENACIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF The present invention relates to an extended release formulation comprising darifenacin or pharmaceutically acceptable salts thereof and one or more release controlling hydrophobic materials optionally coated with combination of one or more release controlling hydrophob... | 12/29/2011 |
| 20110311629 | NON-ADHESIVE ELASTIC GELATIN MATRICES The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s... | 12/22/2011 |
| 20110307054 | IMPLANT COATING WITH NUCLEIC ACIDS One example embodiment of the present invention relates to an implant with a coating or a cavity filling containing a nucleic acid, which i) can inhibit the expression of at least one representative of the Ras gene family by means of RNA interference; or ii) encodes for... | 12/15/2011 |
| 20110305760 | TISSUE REGENERATION SYSTEM A system for growing tissue based upon layers of an inorganic extracellular matrix, wherein each layer of the inorganic matrix is designed to dissolve at a separate rate and result in sequential growth factor delivery upon its dissolution.... | 12/15/2011 |
| 20110306500 | Method of Treating a Material Using a Sol-gel Derived Composition Disclosed is a method and system that includes treating a material by applying a sol-gel derived composition loaded with a first sorbate under conditions effective to treat the material with the first sorbate.... | 12/15/2011 |
| 20110293722 | HYDROGEL SPONGES, METHODS OF PRODUCING THEM AND USES THEREOF A macroporous hydrogel sponge is provided selected from: (i) a synthetic polymer hydrogel sponge, and (ii) a synthetic polymer-polypeptide conjugate hydrogel sponge, the macroporous hydrogel sponge being at least 20% porous and having a pore diameter of 50-1000 μm, whe... | 12/01/2011 |
| 20110293720 | PROGESTIN-CONTAINING DRUG DELIVERY SYSTEM The present invention relates to drug delivery compositions in the form of thin water-soluble films (wafers), which contain small particles that comprise at least one progestin and at least one protective agent. The protective agent provides effective taste-masking of t... | 12/01/2011 |
| 20110287078 | NOVEL POROUS BIOMATERIALS The invention provides porous biomaterials and methods for forming porous biomaterials. The porous biomaterials of the invention comprise a biocompatible polymer scaffold defining an array of pores, wherein substantially all the pores have a similar diameter, wherein th... | 11/24/2011 |
| 20110268792 | SURFACE ACTIVE PROTEINS AS EXCIPIENTS IN SOLID PHARMACEUTICAL FORMULATIONS The invention relates to a use of surface active hydrophobins for applications in pharmaceutical technology, in particular as excipients for galenic use. Provided is a method for either admixture of hydrophobins to galenic compositions or for treating the surface of pha... | 11/03/2011 |
| 20110262542 | Controlled Delivery of Tetracycline Compounds and Tetracycline Derivatives A composition is provided for delivering a tetracycline compound to a mammal. The composition includes an antibiotic tetracycline compound and a controlled-release agent having at least one controlled-release agent. The tetracycline compound is associated with the contr... | 10/27/2011 |
| 20110262541 | FOAM-FORMED COLLAGEN STRAND Foam-formed collagen strands and methods for forming strands involve depositing a dispersed solution of an isolated cleaned, de-fatted, enzymatically-treated (or non-enzyme treated) human-derived collagen product having a preserved amount of its natural constituents int... | 10/27/2011 |
| 20110262516 | AUTOLOGOUS CELLS ON A SUPPORT MATRIX FOR TISSUE REPAIR The present invention relates to a method for the effective treatment of tissue defects and for tissue regeneration. The method includes seeding autologous cells on a support matrix and implanting the cell-seeded support matrix into a site of transplantation. The presen... | 10/27/2011 |
