"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Application No. | Application Title | Issue Date |
| 20120020877 | PROCESS AND INTRA-CERVICAL DEVICE FOR THE LOCAL RELEASE OF DRUGS IN THE LOCAL-REGIONAL TREATMENT OF CERVICAL CANCER An intrauterine device and more specifically an intracervical device (ICD) for the local release of drugs in the loco-regional treatment of tumours of the uterine cervix comprises an elongated stem (2) to be positioned in the cervical canal (15), this stem... | 01/26/2012 |
| 20110305744 | PREPARATION FOR VAGINAL AND RECTAL USE AND RELATIVE PRODUCTION METHOD A preparation for vaginal and rectal use comprising hyaluronic acid, with an average particle size comprised between about 50 micrometers and about 200 micrometers and a molecular weight comprised between about 1,000,000 Da and about 1,800,000 Da.... | 12/15/2011 |
| 20110293686 | Anti-viral compositions and methods for administration Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, articles of manufacture, systems, and devices. Certain embodiments relate to anti-viral compositions, methods, articles of manufacture, systems and devices.... | 12/01/2011 |
| 20110280922 | DEVICES AND METHODS FOR TREATING AND/OR PREVENTING DISEASES The invention relates to a therapeutic device for the delivery of therapeutic agents, e.g. a peptide such as leuprolide, via the vagina to a female mammal. In some embodiments, the invention also relates to methods for the treatment of obesity and eating disorders, diab... | 11/17/2011 |
| 20110274740 | METHODS OF REDUCING SYMPTOMS IN SUBJECTS USING SINGLE DOSAGE FORMS WITH TAPERING RELEASE RATES The present invention is directed to methods of reducing symptoms associated with an abrupt reduction in an endogenous or exogenous chemical in subjects, the methods comprising: (a) administering to the subject a single dosage form comprising an active agent, wherein th... | 11/10/2011 |
| 20110236462 | INTRAVAGINAL DRUG DELIVERY DEVICE Described herein is an intravaginal drug delivery system. In an embodiment the intravaginal drug delivery system includes a progestin and estrogen compound, and releases the active ingredients in a fixed physiological ratio over a prolonged period of time to produce a c... | 09/29/2011 |
| 20110189257 | NANOPARTICLE BASED THERAPY FOR AGGREGATING MUCIN There are provided compositions and methods to aggregate mucus using a plurality of positively charged nanoparticles. There are also provided compositions and methods for inducing contraception in the subject.... | 08/04/2011 |
| 20110098631 | MEDICAL DEVICES FOR TREATING UROLOGICAL AND UTERINE CONDITIONS The present invention relates to implantable or insertable medical devices that treat uterine and urological conditions that cause chronic pelvic pain and other symptoms. In another aspect, the present invention relates to methods of manufacturing such implantable or in... | 04/28/2011 |
| 20110059154 | CCR5 ANTAGONISTS AS PROPHYLACTICS FOR PREVENTING HIV INFECTION AND METHODS OF INHIBITING TRANSMISSION OF SAME Topical cream, ointment, lotion, gel, foam formulations and slow release formulations or devices are provided including certain CCR5 antagonists as prophylactics for the prevention, retardation or inhibition of transmission of Human Immunodeficiency Virus (HIV) infectio... | 03/10/2011 |
| 20110045049 | IMMUNOMODULATING COMPOSITIONS AND METHODS OF USE This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a ... | 02/24/2011 |
| 20110027341 | DEVICE FOR IN SITU PRODUCTION AND TOPICAL ADMINISTRATION OF ALLICIN The present invention relates to a drug delivery device that is useful for topical treatment of various infections such as skin and nail, or vaginal infections. More specifically, the invention provides a device for topical administration of allicin to an infection site... | 02/03/2011 |
| 20110008409 | PHARMACEUTICAL PREPARATION CONTAINING A GESTAGEN, AND KIT AND METHOD FOR TREATING ENDOMETRIOSIS USING THE PREPARATION The pharmaceutical preparation for treating endometriosis contains at least 28, preferably 30, daily dose units, each of which contain dienogest, cyproterone acetate, or chlormadinone acetate at a daily dose that is at most twice that required to inhibit ovulation toget... | 01/13/2011 |
| 20100330149 | Solid Drug Tablets for Implantable Drug Delivery Devices A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of an aminoamide, an aminoester, and a combination thereof. The drug tablet ... | 12/30/2010 |
| 20100330138 | BIOSTABLE, MULTIPURPOSE, MICROBICIDAL INTRAVAGINAL DEVICES Biostable, multipurpose, microbicidal intravaginal devices in the form of rings, ringed-meshes, sponges, or diaphragms for use by women and condoms for use by male partners are provided, wherein each of the devices contains a drug effective in treating a particular vagi... | 12/30/2010 |
| 20100316691 | BIODEGRADABLE INTRAVAGINAL MEDICAL DEVICE FOR DELIVERY OF THERAPEUTICS The present disclosure relates to biodegradable intravaginal rings for the delivery of therapeutic or prophylactic agent, inter alia, antiviral agents. The present disclosure further relates to biodegradable polyurethanes which will allow therapeutic/prophylactic agents... | 12/16/2010 |
| 20100285094 | POLYMERIC COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF Described herein are polymeric compositions that comprise at least one polymer residue and at least one crosslinking moiety, wherein the polymer residue is crosslinked by the crosslinking moiety and wherein the crosslinking moiety is formed from a reaction between a bor... | 11/11/2010 |
| 20100166826 | BIODEGRADABLE INTRAVAGINAL DEVICES FOR DELIVERY OF THERAPEUTICS The present disclosure relates to biodegradable intravaginal rings for the delivery of therapeutic or prophylactic agent, inter alia, antiviral agents. The present disclosure further relates to biodegradable polyurethanes which will allow therapeutic/prophylactic agents... | 07/01/2010 |
| 20100104619 | DELIVERY SYSTEM FOR A NON-STEROIDAL NON-IONIZED HYDROPHILIC DRUG This invention relates to an extended release formulation comprising a solid non-steroidal non-ionized hydrophilic drug, having a molecular weight below 500 Dalton and having a solubility of at least 0.1 wt % in ethylene vinyl acetate copolymer having a vinyl acetate co... | 04/29/2010 |
| 20100098745 | Methods for delivery of medication using dissolvable devices A method utilizing a dissolvable device for the internal delivery of medication and more particularly to the use of films, fibers or non-woven fabrics made of a safe polymer material incorporating a medication that is released by dissolution of the films, fibers or non-... | 04/22/2010 |
| 20090324692 | Polyurethane Elastomers A linear polymer is obtained by reacting together a polyethylene glycol or polypropylene glycol; a PEG-PPG-PEG or PPG-PEG-PPG block copolymer; a difunctional amine or diol; and a diisocyanate. A controlled release composition comprises the polymer together with an activ... | 12/31/2009 |
| 20090311305 | Vaginal therapeutic device including copper metal and method of treating the vaginal using the vaginal therapeutic device A vaginal therapeutic device made of copper metal has a shape to fit in the vagina and utilizes the copper metal as an antimicrobial agent to therapeutically treat abnormal biological conditions in the vagina.... | 12/17/2009 |
| 20090304776 | TRANSMUCOSAL DELIVERY OF THERAPEUTIC AGENTS AND METHODS OF USE THEREOF Described herein is a transmucosal delivery device and their use for delivering bioactive agents across a mucosal membrane. The delivery devices contain a pharmaceutically acceptable oxidizing and agents that facilitates the delivery of the blood stream across the mucos... | 12/10/2009 |
| 20090291117 | FEMALE BARRIER TO PREVENT INFECTIONS FROM HUMAN IMMUNODEFICIENCY VIRUS The Human Immunodeficiency Virus posses a significant threat to the world's population. Current strategies utilized to treat infectious agents have not been adequate to eradicate such deadly viral infections. HIV seeks out its host, a T-Helper cell, by having utilizing ... | 11/26/2009 |
| 20090291118 | UNIVERSAL BARRIER TO PREVENT INFECTIONS FROM HUMAN IMMUNODEFICIENCY VIRUS The Human Immunodeficiency Virus poses a significant threat to the world's population. Current strategies to treat infectious agents have not been adequate to eradicate such deadly viral infections. HIV seeks out its host, a T-Helper cell, by utilizing glycoprotein 120 ... | 11/26/2009 |
| 20090291119 | POLYMERIC IMPLANT AND A PROCESS FOR OBTAINING A POLYMERIC IMPLANT The polymeric implant is obtained from a renewable source, comprising a body formed by at least one biodegradable polymer selected from the group consisting of polyhydroxyalcanoates (PHAs) and copolymers thereof, said body incorporating, in its micro-structure, an activ... | 11/26/2009 |
| 20090274746 | METHODS AND COMPOSITIONS FOR CONTROLLED DELIVERY OF PHYTOCHEMICAL AGENTS The presently-disclosed subject matter provides compositions and methods for treating a cancer by providing a composition comprising a biocompatible polymeric matrix incorporating an effective amount of a phytochemical agent, a combination of phytochemical agents, or a ... | 11/05/2009 |
| 20090220574 | SURAMIN AND DERIVATIVES THEREOF AS TOPICAL MICROBICIDE AND CONTRACEPTIVE The present invention is directed to methods of inhibiting STDs by topically administering suramin or a derivative thereof to actual or potential sites of infection, and methods of preventing pregnancy by topically applying suramin or a derivative thereof intravaginally... | 09/03/2009 |
| 20090208551 | Biological implantation material and method for preparing same The present invention relates to a biological implantation material and method of preparing the same, which comprises the steps of: (i) treating a tissue derived from animal or human with alcohol; (ii) contacti... | 08/20/2009 |
| 20090123512 | Quorum Sensing Modulators Compounds described herein are useful in modulating bacterial quorum sensing.... | 05/14/2009 |
| 20090098188 | Method for delivery of medication using a dissolvable device A method utilizing a dissolvable device for the internal delivery of medication and more particularly to the use of films made of a safe polymer material incorporating a medication that is released by dissolution of the film over time, and more particularly a treatment ... | 04/16/2009 |
| 20090081278 | Drug Delivery System The subject invention provides a drug delivery system comprising at least one compartment comprising (i) a drug-loaded thermoplastic polymer core layer, (ii) a drug-loaded thermoplastic polymer intermediate layer and (iii) a non-medicated thermoplastic polymer skin cove... | 03/26/2009 |
| 20090035352 | Drug Delivery Particle A drug delivery particle including a reservoir region having primarily large pores and a metering region. The particle can be highly spherical.... | 02/05/2009 |
| 20090004246 | INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE DELIVERY OF MACROMOLECULES AND WATER-SOLUBLE DRUGS An intravaginal drug delivery device comprises a device body comprising a hydrophobic carrier material having at least one channel defining at least one opening to the exterior of said device body, said at least one channel being adapted to receive at least one drug-con... | 01/01/2009 |
| 20080268022 | MEHTODS FOR TREATING AND PREVENTING AILMENTS CAUSED BY HUMAN PAPILLOMAVIRUS This application discusses methods and compositions for preventing and treating ailments and/or diseases, such as HPV, with carrageenan. Moreover, methods and systems for administering carrageenan are described herein. In some embodiments, carrageenan (i.e., carrageenan... | 10/30/2008 |
| 20080254097 | Method and Implant Material for Treatment of Urinary Incontinence Methods and implant materials are provided for treating urinary incontinence. The methods may include providing a composition that includes at least one pharmaceutically active formulation capable of retropubic fat dissolution; and introducing the composition into the r... | 10/16/2008 |
| 20080241446 | Composite material and methods of filament winding, pultrusion and open molding that material A composite material is provided. The composite material includes a continuous roving made from a material selected from a group consisting of natural fibers, mineral fibers, synthetic fibers, kenaf fibers, hemp fibers, carbon fibers, glass fibers, aramid fibers and mix... | 10/02/2008 |
| 20080124380 | Contraceptives Based on SP22 and SP22 Antibodies Oral, topical and injectable contraceptives, which are based on sperm protein 22 kDa (SP22) polypeptides and antibodies and infertility diagnostics are provided.... | 05/29/2008 |
| 20080124379 | Compositions and methods for making therapies delivered by viral vectors reversible for safety and allele-specificity The present invention is directed to compositions methods and kits for regulation of gene therapies, including, without limitation, reversible gene therapies and allele-specific therapies.... | 05/29/2008 |
| 20080075758 | Non-Antibiotic Intervention of Chlamydial Infection Methods for treating or reducing the risk of transmission of chlamydia to a recipient by topically applying a metalloprotease inhibitor to a site on the recipient which is likely to be exposed to Chlamydia. Topical compositions containing metalloprotease inhibitors are ... | 03/27/2008 |
| 20080057107 | COMPOSITIONS FOR VAGINAL TREATMENT The invention provides mannose phosphate and salts thereof for increasing vaginal cell growth, vaginal cell maturation and vaginal moisture, as well as compositions, articles and methods for treating and preventing vaginal conditions characterized by poor vaginal cell g... | 03/06/2008 |