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Class 424/263.1 - Chlamydia (e.g., Chlamydia trachomatis, etc.)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the bacterium is of the genus Chlamydia.
No. of applications: 47
Last issue date: 02/02/2012


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Application No.Application TitleIssue Date
20120027793COMPOSITIONS COMPRISING CHLAMYDIA ANTIGENS
There is provided a composition for inducing an immune response to a Chlamydia species in a subject, the composition comprising one or more than one polypeptides selected from the group consisting of ribosomal peptide L/RplF, ribosomal protein L6 (RplF), PmpG pro...
02/02/2012
20120009220Low Antigen-dose Immunization for Maximizing T-helper Cell 1 (Th1) Immunity Against a Pathogen
Disclosed are compositions, kits, and methods for inducing an immune response against disease. The dosage of antigen contained or utilized in the presently disclosed compositions, kits, and methods is substantially lower than dosages conventionally used in the field. Th...
01/12/2012
20120003277NANOEMULSION VACCINES
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides nanoemulsion compositions harboring one or more immunogens within the oil phase of the nanoemulsion and methods of using the sam...
01/05/2012
20110300206VACCINES AGAINST CHLAMYDIAL INFECTION
The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention...
12/08/2011
20110300179Novel Compositions and Uses Thereof
The present invention provides a cellular vaccine for therapeutic or prophylactic treatment of a pathological condition, the vaccine comprising or consisting of a population of CD 4+ T cells modified such that they contain an antigenic component, and/or a nucleic acid m...
12/08/2011
20110293664CHLAMYDIA ANTIGENS AND USES THEREOF
Disclosed are novel chlamydia antigens, nucleic acids encoding the antigens, and immunogenic compositions including the antigens. Methods of using the antigens to elicit immune responses (e.g., T cell-mediated and/or B cell-mediated immune responses) comprising administ...
12/01/2011
20110293723SYNTHETIC NANOCARRIER COMBINATION VACCINES
Disclosed are dosage forms and related methods, that include a first population of synthetic nanocarriers that have one or more first antigens coupled to them, one or more second antigens that are not coupled to the synthetic nanocarriers, and a pharmaceutically accepta...
12/01/2011
20110287087MODIFIED CATIONIC LIPOSOME ADJUVANS
The present invention relates to the use of vaccines with adjuvants comprising cationic liposomes where neutral lipids has been incorporated into the liposomes to change the gel-liquid phase transition and thereby modifying the IgG sub-type response and enhancing the CD...
11/24/2011
20110268763POLYNUCLEOTIDES THAT STIMULATE NEUTROPHILS
The polynucleotides of the present invention are complementary to the Initiation Sites of microbes. Invading organisms, sensing the pH and nutrient deprivation of a physiologic environment quickly release these nucleotides triggering rapid growth and mutation—attribut...
11/03/2011
20110256094Methods and Compositions for Chlamydial Antigens for Diagnosis and Treatment of Chlamydial Infection and Disease
Disclosed are isolated Chlamydia trachomatis proteins, methods of fusion protein and associated antibody production, and methods of using isolated proteins and antibodies in diagnosis and detection. Also disclosed are compositions comprising isolated proteins, wh...
10/20/2011
20110159041Chlamydia Trachomatis Genomic Sequence and Polypeptides, Fragments Thereof and Uses Thereof, in Particular for the Diagnosis, Prevention and Treatment of Infection
The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia trachomatis, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication proce...
06/30/2011
20110142872COMPOUNDS AND METHODS FOR TREATMENT AND DIAGNOSIS OF CHLAMYDIAL INFECTION
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutica...
06/16/2011
20110123491METHODS AND COMPOSITIONS FOR IMMUNIZATION AGAINST CHLAMYDIAL INFECTION AND DISEASE
The present invention provides Chlamydia proteins and compositions and methods of use in the treatment/prevention of chlamydial infection in a subject, for eliciting an immune response in a subject and for reducing the likelihood of infertility and reducing the i...
05/26/2011
20110110979METHOD AND VACCINE FOR OPTIMIZING THE SPECIFIC IMMUNE RESPONSES
The present invention relates to a method for treating an infection or disease or lesion, in particular an HPV infection. Furthermore, it relates to a vaccine for treating a Human Papillomavirus (HPV) infection or an associated disease or lesion in a subject....
05/12/2011
20110104207GYRASE INHIBITORS AND USES THEREOF
The present invention relates to compounds which inhibit bacterial gyrase and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention al...
05/05/2011
20110070266IMMUNOGENIC COMPOSITIONS FOR CHLAMYDIA TRACHOMATIS
The invention relates to immunogenic compositions comprising combinations of Chlamydia trachomatis antigens and their use in vaccines. The composition may comprise at least two components, one component of which comprises Chlamydia trachomatis antigens for...
03/24/2011
20110027321Chlamydia Vaccine Comprising HtrA Polypeptides
The present invention provides vaccine compositions useful in prevention and treatment of Chlamydia sp. (e.g., C. trachomatis or C. pneumoniae) infection. Provided are polypeptide vaccine antigens comprising Chlamydia HtrA-derived sequences, ...
02/03/2011
20110014210CHLAMYDIA VACCINE
Compositions and methods for the treatment of Chlamydial infection are disclosed. The compositions provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compos...
01/20/2011
20100310585THE USE OF MONOMYCOLYL GLYCEROL (MMG) AS AN ADJUVANT
Here we identify MMG and its alpha- and ketomycolic acid derivatives as highly bioactive lipids derived from M. bovis BCG (Copenhagen) capable of stimulating and activating human DC's at exceedingly low doses. In addition to their direct role as immunostimulators...
12/09/2010
20100297164Chlamydial Antigens
The invention is in the field of immunology and vaccinology. In particular, it relates to antigens derived from Chlamydia trachomatis that are expressed on the cell surface and so are ideal for use in immunisation as well as combinations of these antigens....
11/25/2010
20100284963GROWTH REGULATABLE RECOMBINANT BCG IMMUNOGENIC COMPOSITIONS
Immunogenic compositions comprising growth regulatable recombinant intracellular pathogens that have been transformed to express recombinant immunogenic antigens of the same or other intracellular pathogens are provided. Exemplary immunogenic compositions include, but a...
11/11/2010
20100285060ALPHA THYMOSIN PEPTIDES AS VACCINE ENHANCERS
The present invention provides methods of vaccination as well as pharmaceutical combinations and kits for enhancing vaccine effectiveness, including for immunodeficient or immunecompromised patients, including non-responders and low-responders to vaccination. As disclos...
11/11/2010
20100278854CHLAMYDIA ANTIGENS
Chlamydia antigens (e.g., polypeptides, polypeptide fragments, and fusion proteins) are provided. Also provided are vaccines and pharmaceutical compositions for treating or preventing a bacterial infection, such as Chlamydia, in a subject....
11/04/2010
20100272758Viable non-toxic gram-negative bacteria
The present invention provides non-toxic Gram-negative bacteria. In particular, the present invention provides viable Gram-negative bacteria (e.g., E. coli) substantially lacking lipopolysaccharide (LPS, endotoxin) within the outer membrane. The present invention...
10/28/2010
20100260791CHLAMYDIA ANTIGENS
Chlamydia antigens (e.g., polypeptides, polypeptide fragments, and fusion proteins) are provided. Also provided are vaccines and pharmaceutical compositions for treating or preventing a bacterial infection, such as Chlamydia, in a subject....
10/14/2010
20100255002Immunogenic compositions for chlamydia trachomatis
The invention relates to compositions comprising combinations of Chlamydia trachomatis antigens and their use in vaccines. Specific combinations may be selected from a first antigen group of PepA, LcrE, ArtJ, DnaK, and CT398, and a second antigen group of PepA, L...
10/07/2010
20100226975Compositions and Methods for Stabilizing Lipid Based Adjuvant Formulations Using Glycolipids
The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as a...
09/09/2010
20100136043COMPOSITION COMPRISING IMMUNOGENIC MICROPARTICLES
The invention provides an immunogenic composition comprising at least one antigen in association with micropar-tides, wherein the microparticles are in the same size range as viruses. In addition the invention also provides vaccine compositions and methods of eliciting ...
06/03/2010
20100119549CHLAMYDIAL ANTIGENS AS REAGENTS FOR DIAGNOSIS AND TREATMENT OF CHLAMYDIAL INFECTION AND DISEASE
The present invention provides Chlamydia proteins and methods of use in diagnostic and detection assays as well as in treatment and immunization protocols....
05/13/2010
20100098697Chlamydia trachomatis antigens
Proteins encoded by Chlamydia trachomatis which are immunogenic in humans as a consequence of infection have been identified using Western blots of two-dimensional electrophoretic maps. Several known immunogens were identified, as were proteins not previously kno...
04/22/2010
20100055130STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS
The invention provides proteins from Staphylococcus aureus, including amino acid sequences and corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies, and as targets for antibiotics....
03/04/2010
20090324642METHOD OF ELICTING OR INDUCING AN IMMUNE RESPONSE
A method for eliciting or inducing an immune response in a human or animal subject, comprises administering to said subject a composition comprising an antigen and an adjuvant, wherein the composition is administered to the subject by the intra-lung route....
12/31/2009
20090324639COMPOSITIONS AND METHODS FOR ACTIVATING INNATE AND ALLERGIC IMMUNITY
Methods for making and using therapeutic formulations of Proteosome-based immunoactive compositions are provided. The immunogenic compositions, which include Proteosomes and liposaccharides, may be used to elicit or enhance a nonspecific innate immune response to, for e...
12/31/2009
20090304751VAULT COMPOSITIONS FOR IMMUNIZATION AGAINST CHLAMYDIA GENITAL INFECTION
Methods and compositions are provided herein for immunizing a subject against Chlamydial genital infection by administering to the subject an effective amount of a Chlamydial immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-l...
12/10/2009
20090297551ADJUVANT
This invention relates to a novel adjuvant comprising a transfection reagent, and to uses of this adjuvant. In particular, the adjuvant may be used in compositions for eliciting an immune response and in vaccines....
12/03/2009
20090263421CELLULAR VACCINE
The present invention provides a cellular vaccine for therapeutic or prophylactic treatment of a pathological condition, the vaccine comprising or consisting of a population of CD 4+ T cells modified such that they contain an antigenic component, and/or a nuc...
10/22/2009
20090252765BACILLE CALMETTE-GUERIN (BCG)-BASED ANTI-ATHEROMA VACCINE AND METHODS OF USE THEREOF
The invention relates to a recombinant Mycobacterium bovis which expresses at least one Chlamydophila pneumoniae antigen....
10/08/2009
20090142376CHLAMYDIA POLYPEPTIDES AND CORRESPONDING DNA FRAGMENTS AND USES THEREOF
The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector containing a nucleotide sequence ...
06/04/2009
20090098165METHODS AND COMPOSITIONS FOR IMMUNIZATION AGAINST CHLAMYDIAL INFECTION AND DISEASE
The present invention provides Chlamydia proteins and compositions and methods of use in the treatment/prevention of chlamydial infection in a subject, for eliciting an immune response in a subject and for reducing the likelihood of infertility and reducing the i...
04/16/2009
20080311156VACCINES
The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an immunostimulatory oligonucleotide, optionally with a carrier. Also provided by ...
12/18/2008
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