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| Application No. | Application Title | Issue Date |
| 20120107340 | COMPOSITIONS FOR IMMUNISING AGAINST STAPHYLOCOCCUS AUREUS An effective Staphylococcus aureus vaccine may require several antigenic components, and so various combinations of S. aureus antigens are identified for use in immunisation. These polypeptides may optionally be used in combination with S. aureus sa... | 05/03/2012 |
| 20120107327 | IMMUNOGENIC COMPOSITIONS OF STAPHYLOCOCCUS AUREUS ANTIGENS The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conj... | 05/03/2012 |
| 20120034230 | Cna-B DOMAIN ANTIGENS IN VACCINES AGAINST GRAM POSITIVE BACTERIA The invention provides protective antigens which are useful in vaccine compositions to induce protection against gram positive bacteria, particularly against S. agalactiae, S. pyogenes, S. pneumoniae, S. aureus, S. suis, and S. equi. ... | 02/09/2012 |
| 20120003277 | NANOEMULSION VACCINES The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides nanoemulsion compositions harboring one or more immunogens within the oil phase of the nanoemulsion and methods of using the sam... | 01/05/2012 |
| 20110311588 | AGENTS AND TREATMENT FOR SNORING AND RESPIRATORY EFFORT RELATED AROUSALS IN SLEEP A method for prophylaxis or treatment of respiratory effort related arousals during sleep of a subject is provided. The method comprises administering to the subject an effective amount of an agent for reducing or inhibiting infection or colonisation of the nasal cavity... | 12/22/2011 |
| 20110293723 | SYNTHETIC NANOCARRIER COMBINATION VACCINES Disclosed are dosage forms and related methods, that include a first population of synthetic nanocarriers that have one or more first antigens coupled to them, one or more second antigens that are not coupled to the synthetic nanocarriers, and a pharmaceutically accepta... | 12/01/2011 |
| 20110274720 | CAPSULAR GRAM-POSITIVE BACTERIA BIOCONJUGATE VACCINES The present invention encompasses a novel S. aureus bioconjugate vaccine. More generally, the invention is directed to Gram-positive and other bioconjugate vaccines containing a protein carrier, at least one polysaccharide such as a capsular Gram-positive polysac... | 11/10/2011 |
| 20110268757 | USE OF PHENOL-SOLUBLE MODULINS FOR VACCINE DEVELOPMENT The invention relates to methods for increasing immunogenicity of an antigenic peptide by means of its covalent coupling to a modulin derived peptide (PSM, phenol soluble modulin). In particular, the binding of PSMα, PSMγ and PSMδ peptides to an antigen (from a patho... | 11/03/2011 |
| 20110268763 | POLYNUCLEOTIDES THAT STIMULATE NEUTROPHILS The polynucleotides of the present invention are complementary to the Initiation Sites of microbes. Invading organisms, sensing the pH and nutrient deprivation of a physiologic environment quickly release these nucleotides triggering rapid growth and mutation—attribut... | 11/03/2011 |
| 20110262477 | Compositions and Methods Related to Bacterial EAP, EMP, and/or ADSA Proteins The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria... | 10/27/2011 |
| 20110256179 | PHARMACEUTICAL PREPARATION COMPRISING A COMBINATION OF STREPTOCOCCUS STRAINS AND LACTOBACILLUS STRAINS A pharmaceutical preparation for prophylaxis against and treatment of Staphylococcus induced infections or conditions in humans and animals, is disclosed, wherein it comprises a combination of a) one or more viable α-Streptococcus strains chosen from the ... | 10/20/2011 |
| 20110206676 | COMPOSITIONS AND METHODS RELATED TO STAPHYLOCOCCAL BACTERIUM PROTEINS The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria... | 08/25/2011 |
| 20110195093 | Tissue Targeted Antigenic Activation of the Immune Response to Treat Cancers The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated.... | 08/11/2011 |
| 20110189223 | VACCINE The present invention provides an immunogenic composition comprising an antigen or antigen composition and an adjuvant composition comprising an oil in water emulsion.... | 08/04/2011 |
| 20110177111 | PROTECTIVE VACCINE AGAINST STAPHYLOCOCCUS AUREUS BIOFILMS COMPRISING CELL WALL-ASSOCIATED IMMUNOGENS Vaccine formulations effective against Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA) are disclosed, as well as methods of using the vaccine formulations in the treatment, prevention and prophylaxis of Staphylococcus... | 07/21/2011 |
| 20110171237 | PHEP, AN AMINO ACID PERMEASE OF STAPHYLOCOCCUS AUREUS The present invention relates to antigenic polypeptides expressed by pathogenic microbes, including antigenic polypeptides encoded by the nucleic acid sequence of FIG. 1, vaccines comprising the antigenic polypeptides and therapeutic antibodies directed to the an... | 07/14/2011 |
| 20110150918 | TREATMENT OF MICROBIAL INFECTIONS The present invention is directed to improved microbial antigen vaccines, pharmaceutical compositions, immunogenic compositions and antibodies and their use in the treatment of microbial infections, particularly those of bacterial origin, including Staphylococcal origin... | 06/23/2011 |
| 20110150931 | RAPID RESPONSES TO DELAYED BOOSTER IMMUNISATIONS Booster immunization can lead to rapid induction of protective immunity against pathogens (e.g. ≦7 days after the booster dose). This rapid response means that booster immunization can be used at short notice prior to an event that might require an activated immune re... | 06/23/2011 |
| 20110117099 | INHIBITING STAPHYLOCOCCUS EPIDERMIDIS INFECTIONS The invention relates to Staphylococcus epidermidis peptides, antibodies and nucleic acids that can inhibit Staphylococcus epidermidis infection of a mammalian subject and colonization of a medical device in the mammal.... | 05/19/2011 |
| 20110104207 | GYRASE INHIBITORS AND USES THEREOF The present invention relates to compounds which inhibit bacterial gyrase and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention al... | 05/05/2011 |
| 20110064723 | Formulation for room temperature stabilization of a live attenuated bacterial vaccine This invention provides methods and compositions for stabilizing proteins and vaccines in dried formulations. In particular, a cavitation method and compositions of preparing a dried vaccine are provided that stabilize the viability of live bacteria and live virus vacci... | 03/17/2011 |
| 20110020402 | Method For Identification, Isolation And Production Of Antigens To A Specific Pathogen Described is a method for identification, isolation and production of hyperimmune serum-reactive antigens from a specific pathogen, a tumor, an allergen or a tissue or host prone to autoimmunity, said antigens being suited for use in a vaccine for a given type of animal... | 01/27/2011 |
| 20110008385 | Immunogenic composition The present application relates to immunogenic compositions comprising staphylococcal PNAG and Type 5 and/or 8 capular polysaccharide or oligosaccharide from S. aureus. Vaccines, methods of treatment using and processes to make an immunogenic composition comprisi... | 01/13/2011 |
| 20100330124 | VACCINE COMPOSITIONS AND METHODS OF USE TO PROTECT AGAINST INFECTIOUS DISEASE The present invention provides a novel immunogenic composition, vaccine and methods for making and using the immunogenic composition and vaccine. The immunogenic composition is capable of providing an immune response and/or a protective immunity into subjects, preferabl... | 12/30/2010 |
| 20100285064 | ADJUVANT COMPOSITION FOR VACCINE The present invention provides a Withania somnifera fraction rich in withanolides and a vaccine comprising a “Withania somnifera fraction” as an adjuvant.... | 11/11/2010 |
| 20100260801 | Polysaccharide vaccine for staphylococcal infections The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. The invention... | 10/14/2010 |
| 20100196422 | NOVEL POLYPEPTIDES FOR ISOLATING IN VITRO AND PREVENTING STAPHYLOCCOCAL INFECTIONS ON JOINT PROSTHESES AND OTHER IMPLANTED FOREIGN MATERIALS The invention concerns novel polypeptides, or parts or variants of the novel polypeptides, the use of sequences encoding the polypeptides and the use of antibodies directed against the polypeptides in the field of in vitro diagnosis of a Staphylococcus epidermidis | 08/05/2010 |
| 20100189748 | INACTIVATED STAPHYLOCOCCAL WHOLE-CELL VACCINE A vaccine is disclosed that is protective against pathogenic bacterial species, typically staphylococcal species, and includes methods to prepare said vaccine and to culture pathogenic bacteria.... | 07/29/2010 |
| 20100158952 | MICROORGANISMS OR FRACTIONS THEREOF CAPABLE OF ACTIVATING CELLULAR IMMUNITY AGAINST CARBOHYDRATES The present invention relates to the field of prevention and treatment of tumors and gastrointestinal disorders. The present invention relates to the prevention and treatment of Core-1-positive carcinomas. The invention relates to coreotics and a method of producing the... | 06/24/2010 |
| 20100158941 | Compositions and Methods for Treating Microbial Infections The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an effective amount of bacterial lysate compositions for the treatment of pathol... | 06/24/2010 |
| 20100150929 | Peptide Associated with Rheumatic Fever (PARF) and Its Use as a Diagnostic Marker The present invention relates to a streptococcal octapeptide AXYLXXLN, and preferably to the octapeptide AXYLZZLN, designated as peptide associated with rheumatic fever (PARF) that, through its interaction with human collagen, plays a crucial role in the pathogenesis of... | 06/17/2010 |
| 20100150956 | MULTICOMPONENT VACCINES Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful selec... | 06/17/2010 |
| 20100143400 | Immunostimulatory Oligonucleotides The invention relates to immunostimulatory oligonucleotides and methods of using immunostimulatory oligonucleotides to induce an antigen-specific immune response. The invention further relates to a vaccine that comprises an immunostimulatory oligonucleotide and an antig... | 06/10/2010 |
| 20100136043 | COMPOSITION COMPRISING IMMUNOGENIC MICROPARTICLES The invention provides an immunogenic composition comprising at least one antigen in association with micropar-tides, wherein the microparticles are in the same size range as viruses. In addition the invention also provides vaccine compositions and methods of eliciting ... | 06/03/2010 |
| 20100136050 | Extracellular Matrix Materials as Vaccine Adjuvants for Diseases Associated with Infectious Pathogens or Toxins Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases associated with biological toxins. Also provided are methods of preparing an adjuv... | 06/03/2010 |
| 20100104603 | USE OF STAPHYLOCOCCAL SUPERANTIGEN-LIKE PROTEIN 5 (SSL5) IN MEDICINE The present invention relates to Staphylococcal superantigen-like protein 5 (SSL5) or homologues or derivatives thereof for use in medicine, in particular for use in the treatment of indications involving an excessive recruitment of leukocytes, such as stroke, perfusion... | 04/29/2010 |
| 20100055130 | STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS The invention provides proteins from Staphylococcus aureus, including amino acid sequences and corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies, and as targets for antibiotics.... | 03/04/2010 |
| 20100047267 | Staphylococcus aureus proteins and nucleic acids The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotic... | 02/25/2010 |
| 20100021503 | IMMUNOGENIC COMPOSITION The present application relates to immunogenic compositions comprising Type 5 and Type 8 capsular polysaccharide or oligosaccharide from S. aureus. Methods of using and processes to make an immunogenic composition are also described.... | 01/28/2010 |
| 20090285851 | VACCINE COMPRISING MONOCYTE OR IMMATURE MYELOID CELLS (IMC) WHICH WERE LOADED WITH THE LIGAND OF NATURAL KILLER T CELL AND ANTIGEN The present invention relates to an immuno-therapeutic and prophylactic vaccine comprising monocytes or immature myeloid cells (IMCs) loaded with the ligand of natural killer T cell and an antigen for the prevention and treatment of infectious disease or cancer, more pr... | 11/19/2009 |
