Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Application No. | Application Title | Issue Date |
| 20130122106 | DOSAGE FORM, AND METHODS OF MAKING AND USING THE SAME, TO PRODUCE IMMUNIZATION IN ANIMALS AND HUMANS An embodiment of the present invention features a dosage form for administering antigen to cause an immune response in an animal or human subject in the nature of a vaccine. The dosage form comprises spheres having an effective amount of antigen to create an immune resp... | 05/16/2013 |
| 20130122046 | REGULATORY FACTOR OF FOXP3 AND REGULATORY T CELLS AND USE THEREOF Use of an ubiquitination pathway-related factor, its agonist or antagonist in the preparation of a composition for regulating FOXP3, IL-2, and/or IFN-γ activity, in which the ubiquitination pathway-related factor is selected from: Toll-like receptor, ubiquitin ligase, ... | 05/16/2013 |
| 20130121988 | Nucleic Acid of Formula (I): GlXmGn, or (II): ClXmCn, in Particular as an Immune-Stimulating Agent/Adjuvant The present invention relates to a nucleic acid of the general formula (I): GlXmGn, which may be modified by a lipid. The invention relates further to a pharmaceutical composition containing an immune-stimulating agent according to the i... | 05/16/2013 |
| 20130122041 | ATTENUATED EHRLICHIOSIS VACCINE The present invention relates to an attenuated strain of Ehrlichia canis and a vaccine comprising said attenuated strain for protection of mammals against ehrlichiosis. The invention further relates to methods of preventing ehrlichiosis and of attenuating the pat... | 05/16/2013 |
| 20130122044 | NOVEL INTERFERON-ALPHA-PRODUCING BONE MARROW DENDRITIC CELLS A novel dendritic cell type has been identified within bone marrow, termed myelos interferon dendritic cells (miDC). These novel cells possess the high IFN-alpha producing activity of pDC, but they also display a wide TLR responsiveness along with T-cell stimulation cap... | 05/16/2013 |
| 20130115241 | MICROVESICLES DERIVED FROM CELL PROTOPLAST AND USE THEREOF The present application relates to microvesicles derived from a protoplast which is a bacterial, arhaea, fungal or plant cell or the like from which a cell wall is removed. The microvesicles derived from a protoplast enables free loading of a material necessary for diag... | 05/09/2013 |
| 20130108663 | ENHANCING THE T-CELL STIMULATORY CAPACITY OF HUMAN ANTIGEN PRESENTING CELLS IN VITRO AND IN VIVO AND THEIR USE IN VACCINATION New methods of in vitro or in vivo enhancing the T-cell stimulatory capacity of human dendritic cells (DCs) and the use thereof in cancer vaccination are provided. The method includes introduction of different molecular adjuvants to human DCs by contacting or modifying ... | 05/02/2013 |
| 20130101622 | IMIDAZOQUINOXALINE COMPOUNDS AS IMMUNOMODULATORS The invention provides novel compositions comprising imidazoquinoxaline compounds of formula (I) and analogs thereof. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are nov... | 04/25/2013 |
| 20130101629 | HOMOGENOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF The present invention generally relates to homogeneous suspensions of small molecule immune potentiators (SMIPs) that are capable of stimulating or modulating an immune response in a subject in need thereof. The homogeneous suspensions may be used in combinations with v... | 04/25/2013 |
| 20130089570 | ORAL VACCINE COMPROMISING AN ANTIGEN AND A TOLL-LIKE RECEPTOR AGONIST The present invention provides an immunogenic composition comprising one or more antigens and a Toll-like receptor (TLR) agonist in an orally (e.g. sublingually) administered composition.... | 04/11/2013 |
| 20130084306 | VACCINES COMPRISING CHOLESTEROL AND CPG AS SOLE ADJUVANT-CARRIER MOLECULES Described are vaccines having one or more antigens cholesterol and CpG. Aspects of the invention relate to the use of the vaccines of the invention for the treatment and/or prevention of human and animal disorders.... | 04/04/2013 |
| 20130078278 | VACCINE FOR PROTECTION AGAINST SHIGELLA SONNEI DISEASE Compositions and methods for protecting a susceptable host against an infection of Shigella sonnei are disclosed. Such compositions and methods are useful for protecting the host against bacillary dysentery and shigellosis.... | 03/28/2013 |
| 20130071430 | MICRORNA-CONTROLLED RECOMBINANT VACCINIA VIRUS AND USE THEREOF It is intended to provide a vaccinia virus that specifically proliferates in a cancer cell and destroys the cancer cell and to provide use of the virus in cancer treatment. The present invention provides a microRNA-controlled vaccinia virus, in which a target sequence o... | 03/21/2013 |
| 20130071434 | Campylobacter Polypeptides and Methods of Use The present invention provides isolated metal regulated polypeptides obtainable from a Campylobacter spp., and compositions including the polypeptides. The present invention also includes methods for using the compositions disclosed herein, including methods for ... | 03/21/2013 |
| 20130071433 | Interferon-ß Production Modulating Listeria Strains and Methods for Using Same Mutant Listeria bacteria that modulate interferon-B production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject... | 03/21/2013 |
| 20130071431 | Method for Preserving Polypeptides Using A Sugar and Polyethyleneimine The invention relates to the preservation of an active agent, such as a polypeptide, by contacting the active agent with a preservation mixture including a sugar and polyethyleneimine.... | 03/21/2013 |
| 20130064850 | Using Modified Plasmids to Suppress Antibiotic Resistant Pathogens Methods of suppressing at least one species of micro-organism that is pathological to an organism. A first embodiment includes a method of suppressing at least one species of micro-organism that is pathological to an organism. A second embodiment includes a method of su... | 03/14/2013 |
| 20130052227 | HYPERBLEBBING SHIGELLA STRAINS Hyperblebbing Shigella strains are generated by disrupting one or more components of the Tol-Pal system. The blebs from these strains are useful immunogens for vaccination. The individual proteins found in these blebs can also be used as immunogens.... | 02/28/2013 |
| 20130052228 | ATTENUATED FISH VACCINE FOLLOWING CULTURE IN IRON LIMITED MEDIA Protection of fish from bacterial disease by vaccination with a live attenuated strain of the causative bacterium is enhanced when the attenuated strain has been grown in an iron-limited medium.... | 02/28/2013 |
| 20130045228 | VACCINE FOR PROTECTION AGAINST LAWSONIA INTRACELLULARIS The present invention pertains to the use of a non-live carbohydrate containing composition, the carbohydrate being also found in live Lawsonia intracellularis cells in association with the outer cell membrane of these cells, for the manufacture of a vaccine for ... | 02/21/2013 |
| 20130039927 | ANTIGENIC MIMICS OF DISCONTINUOUS EPITOPES OF PATHOGEN RECOGNIZED BY BROADLY NEUTRALIZING ANTIBODIES The present invention relates to an anti-idiotypic polypeptide scaffold that includes two or more peptide sequences that mimic a discontinuous epitope of a pathogen that is recognized by or induces formation of a broadly neutralizing antibody. Using a fibronectin FNfn10... | 02/14/2013 |
| 20130039947 | NOVEL IMMUNOGENS AND METHODS FOR DISCOVERY AND SCREENING THEREOF The present application is generally directed to methods for identifying immunogens from organisms and pathogens, and in particular for identifying immunogens which when administered as vaccines elicit a cellular and/or humoral immune response. The present application i... | 02/14/2013 |
| 20130039958 | METHOD OF VACCINATION The present invention relates to improved methods for vaccination of a subject. Particularly, the present invention discloses the use of skin antigen application to amplify and improve a pre-existing immunity against a selected pathogen in a subject. The present inventi... | 02/14/2013 |
| 20130034556 | FREE HEXASACCHARIDE ISOLATED FROM SEVERAL CAMPYLOBACTER SPECIES An isolated or purified compound is provided, comprising A-GlcNAc[GlcNAc]-GalNAc-GalNAc-QuiNAc4NAc, wherein A is GlcNAc or Glc. There is further provided a vaccine based on such compound, having particular use to treat or prevent an infection caused by a Campylobacte... | 02/07/2013 |
| 20130017215 | SECRETED CAMPYLOBACTER FLAGELLA COREGULATED PROTEINS AS IMMUNOGENS The invention relates to an immunogenic composition composed of secreted polypeptides derived from Campylobacter jejuni non-flagellar proteins that are coordinately expressed with the flagellar regulon. The invention also relates to a method of inducing an immune... | 01/17/2013 |
| 20130017219 | PURIFICATION OF BACTERIAL VESICLES A two stage size filtration process is used to purify immunogenic bacterial vesicles. A first step separates the vesicles from intact bacteria based on their different sizes, with the smaller vesicles passing into the filtrate (permeate). A second step then uses a finer... | 01/17/2013 |
| 20130011437 | Immune compositions for treating H. pylori infection An immune composition for use, via topical administration, in eliciting Th2 or regulatory T cell-mediated immune responses specific to H. pylori. The immune composition, free of both liposaccharides and mammalian proteins, contains a whole-cell H. pylori l... | 01/10/2013 |
| 20120328655 | IMMUNOGENIC COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR INDUCING HUMORAL AND CELLULAR IMMUNE RESPONSES Compositions and methods are provided herein for improved dual immunization strategies that induce in a subject an immune response that includes a humoral immune response and cellular immune response, both CD4 and CD8 T lymphocyte immune responses, thereby providing a c... | 12/27/2012 |
| 20120315264 | ZWITTERIONIC IMMUNOMODULATORS FOR THE TEATMENT OF ASTHMA AND ALLERGY Methods and products for treating and protecting against asthma and allergic conditions are provided. The methods and products are related to certain naturally occurring and synthetic zwitterionic polymers which are found to induce certain T regulatory (Treg) cells and ... | 12/13/2012 |
| 20120308618 | IC31 NANOPARTICLES The invention discloses pharmaceutical compositions in liquid form comprising a peptide with the amino acid sequence KLKL5KLK and an oligodeoxynucleotide with the nucleic acid sequence (dIdC)13 and wherein the peptide and the oligodeoxynucleotide a... | 12/06/2012 |
| 20120301474 | COMPOSITIONS AND METHODS FOR IMMUNIZATION AGAINST DRUG RESISTANT ACINETOBACTER BAUMANNII The present invention provides vaccine compositions comprising OmpA, or antigenic fragments thereof, and related methods of active immunization against A. baumannii infection. The invention also provides antibodies and antigen-binding parts thereof that specifica... | 11/29/2012 |
| 20120294830 | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally activ... | 11/22/2012 |
| 20120288523 | ADMINISTRATION ROUTE FOR A COMPOSITION TO PROTECT AN ANIMAL AGAINST RHODOCOCCUS EQUI The present invention pertains to the use of Rhodococcus equi antigens to manufacture a composition for administration to an animal, to elicit in the animal an immune response directed against Rhodococcus equi bacteria, which composition is in a form suita... | 11/15/2012 |
| 20120282268 | Novel Cell Wall Components of Enterococci and Uses Thereof The present invention relates to enterococcal cell wall components and their uses in the prevention and therapy of bacterial infection.... | 11/08/2012 |
| 20120276140 | COMPOSITIONS AND METHODS FOR ACTIVATING INNATE AND ALLERGIC IMMUNITY Methods for making and using therapeutic formulations of Proteosome-based immunoactive compositions are provided. The immunogenic compositions, which include Proteosomes and liposaccharides, may be used to elicit or enhance a nonspecific innate immune response to, for e... | 11/01/2012 |
| 20120276143 | PROBIOTIC BIFIDOBACTERIUM STRAIN Probiotic Bifidobacterium strain AH1714 is significantly immunomodulatory following oral consumption. The strain is useful as an immunomodulatory biotherapeutic agent.... | 11/01/2012 |
| 20120276136 | CHEMICALLY PROGRAMMABLE IMMUNITY The present invention is related to methods and compositions that are capable of immediately immunizing a human or animal against any molecule or compound. The present invention comprises an immunity linker molecule with at least two sites; (1) a first binding site that... | 11/01/2012 |
| 20120269855 | TOLL-LIKE RECEPTOR 5 LIGANDS AND METHODS OF USE The invention provides methods to elicit an immune response with an immunomodulatory flagellin polypeptide having toll-like receptor 5 (TLR5) binding, and further comprising an ADCC targeting molecule.... | 10/25/2012 |
| 20120263753 | BENZONAPHTHYRIDINE-CONTAINING VACCINES The invention provides, inter alia, immunogenic compositions that comprise (a) a first antigen, (b) polymeric particles and (c) a benzonaphthyridine compound, which compositions elicits an immune response when administered to a vertebrate subject. The invention also pro... | 10/18/2012 |
| 20120263754 | Methods for Enhancing Immunogen Specific Immune Responses by Vectored Vaccines Provided herein are methods for inducing a specific immune response in a subject by administering to the subject an immunogenic composition comprising a recombinant expression vector, or a vector particle comprising the recombinant expression vector, which vector compri... | 10/18/2012 |
