"That the automobile has practically reached the limit of its development is suggested by the fact that during the past year no improvements of a radical nature have been introduced."
Scientific American ; Jan. 2 edition, 1909
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| Application No. | Application Title | Issue Date |
| 20120107356 | COMPOSITION USEFUL AS ROTAVIRUS VACCINE AND A METHOD THEREFOR Compositions and methods related to live or live attenuated pre-conditioned and typical viruses such as rotaviruses are disclosed. The live attenuated rotaviruses exhibit better stability characteristics and are useful for the prevention of a rotavirus infection and/or ... | 05/03/2012 |
| 20110293723 | SYNTHETIC NANOCARRIER COMBINATION VACCINES Disclosed are dosage forms and related methods, that include a first population of synthetic nanocarriers that have one or more first antigens coupled to them, one or more second antigens that are not coupled to the synthetic nanocarriers, and a pharmaceutically accepta... | 12/01/2011 |
| 20110268762 | IMMUNIZATION OF AVIANS BY MUCOSAL ADMINISTRATION OF NON-REPLICATING VECTORED VACCINES The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the invention relates to mucosal administration via aerosol spray to avians of immunogenic and vaccine compositions, including those comprising recombinant hum... | 11/03/2011 |
| 20110243988 | Methods and Compositions for Stabilization of a Virus Vaccine This invention provides compositions and methods for stabilizing a live attenuated virus in dried formulations. In particular, compositions and methods of preparing a dried vaccine are provided that stabilize the viability of live vaccines such as measles and adenovirus... | 10/06/2011 |
| 20110236420 | BLUETONGUE VIRUS RECOMBINANT VACCINES AND USES THEREOF The present invention encompasses BTV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing BTV antigens. The invention also encompasses recombinant vectors encoding and expressing BTV antigens, epitopes or immunogens which can ... | 09/29/2011 |
| 20110223195 | COMPOSITION COMPRISING CHITOSAN FOR OCULAR ADMINISTRATION OF VACCINE(S) TO AVIANS The invention relates to vaccine compositions comprising chitosan and a vaccine which are administered to avian species via the ocular route, and methods or programs of vaccination including use of chitosan in order to increase or enhance cell-mediated immunity in avian... | 09/15/2011 |
| 20110212123 | Immunogenic Substances Comprising a Polyinosinic Acid - Polycytidilic Acid Based Adjuvant The present invention provides a polynucleotide adjuvant (PICKCa) composition and methods of use in eliciting an immune response, in particular a mucosal immune response. The polynucleotide adjuvant comprises of a polyriboinosinic-polyribocytidylic acid (PIC), at least ... | 09/01/2011 |
| 20110177116 | Methods of Immunizing Pregnant Heifers at Three Months of Gestation The present invention discloses methods for protecting newborn calves against neonatal diarrhea by vaccinating pregnant cows and/or pregnant heifers, while minimizing the number of separate occasions producers are required to assemble the cattle.... | 07/21/2011 |
| 20110171316 | EXPRESSION AND ASSEMBLY OF HUMAN GROUP C ROTAVIRUS-LIKE PARTICLES AND USES THEREOF Group C rotaviruses are a cause of acute gastroenteritis in children and adults that is distinct from group A RV. However, human group C rotaviruses cannot be grown in culture, resulting in a lack of tools for detection and treatment of GrpC RV disease. Consequently, th... | 07/14/2011 |
| 20110150928 | UNIQUE AVIAN REOVIRIDAE This invention relates to novel unique strains avian reoviridae that were isolated from severe cases of Runting Stunting Syndrome. The present invention also relates to the isolation and uses of novel unique avian reoviridae, diagnostic assays using nucleotide or amino ... | 06/23/2011 |
| 20110150940 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or... | 06/23/2011 |
| 20110110980 | HETERLOGOUS PRIME-BOOST IMMUNIZATION REGIMEN The invention provides methods of inducing an antigen-specific immune response in a subject by using a combination of immunogenic compositions. Generally, the method involves administering to the subject an effective amount of two different immunogenic compositions, bot... | 05/12/2011 |
| 20110091500 | Inactivated Live-Attenuated Bluetongue Virus Vaccine The invention describes the preparation of an inactivated bluetongue virus (BTV) composition, and in particular a vaccine, using an attenuated live BTV vaccine strain as masterseed. The vaccine can be administered to an animal to prevent bluetongue disease by eliciting ... | 04/21/2011 |
| 20110027316 | BLUETONGUE VIRUS VACCINE AND IMMUNOGENIC COMPOSITIONS, METHODS OF USE AND METHODS OF PRODUCING SAME Provided are immunogenic and vaccine compositions and methods for their preparation and use, which compositions are effective in protecting against, minimizing the severity of, preventing, and/or ameliorating infection of ruminants with Bluetongue virus. Administration ... | 02/03/2011 |
| 20100322971 | METHOD FOR PRODUCING VACCINAL VIRAL STRAIN OF A VIRUS OF THE REOVIRIDAE FAMILY The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus genus.... | 12/23/2010 |
| 20100303859 | VECTORS AND METHOD FOR GENETIC IMMUNIZATION Improved DNA vaccine plasmids are disclosed that contain novel immunostimulatory RNA compositions. The improved plasmids eliminate all extraneous sequences, incorporate a novel antibiotic free short RNA based selectable marker, increase eukaryotic expression using a nov... | 12/02/2010 |
| 20100278857 | Dendritic Cell Binding Proteins and Uses Thereof The present invention provides novel peptides which specifically targets and binds to dendritic cells. Also provided are fusion compositions comprising these peptides and a non-dendritic protein of fragments thereof. Further provided are DNA sequences encoding these pep... | 11/04/2010 |
| 20100278863 | Reoviruses The present invention provides a reverse genetics system for viruses belonging to the Reoviridae (i.e. Reoviruses), various uses thereof, genetically modified Reoviruses, Reovirus selection/production and propagation systems, medicaments and vaccines.... | 11/04/2010 |
| 20100266628 | MACROCYCLIC LACTONE COMBINATION COMPOSITIONS, VACCINES AND METHODS FOR PRODUCING SAME An injectable composition, capable of preventing or controlling parasitic, viral, or bacterial infections or diseases, for example scours, in pregnant cows and viral infections or diseases in neonatal calves by parenterally administering to each cow in a herd of pregnan... | 10/21/2010 |
| 20100233208 | Methods of Treating and Preventing Neurological Symptoms Caused by Avian Reovirus and Novel Associated Characteristics Embodiments of the present invention generally relate to novel methods for the treatment and/or prevention of neurological symptoms caused by an avian reovirus, enteric reovirus strain (ERS), and associated characteristics. Other embodiments generally comprise and immun... | 09/16/2010 |
| 20100226939 | FORMULATIONS FOR PRESERVATION OF ROTAVIRUS This invention provides formulations and methods for stabilizing viruses in liquid and dried formulations. In particular, formulations are provided including Zn2+ cations that stabilize the viability of Rotaviruses. Methods of vaccination include neutralizati... | 09/09/2010 |
| 20100209455 | THERMAL INACTIVATION OF ROTAVIRUS Methods of thermally inactivating a rotavirus are provided according to the present invention which include exposing the rotavirus to a temperature in the range of about 50° C.-80° C., inclusive, for an incubation time sufficient to render the rotavirus incapable of r... | 08/19/2010 |
| 20100150958 | Methods and Compositions for Use of a Coccidiosis Vaccine The invention relates to new vaccine compositions for vaccinating birds.... | 06/17/2010 |
| 20100136043 | COMPOSITION COMPRISING IMMUNOGENIC MICROPARTICLES The invention provides an immunogenic composition comprising at least one antigen in association with micropar-tides, wherein the microparticles are in the same size range as viruses. In addition the invention also provides vaccine compositions and methods of eliciting ... | 06/03/2010 |
| 20100112078 | POLYMER PARTICLES BASED VACCINE The present invention provides a vaccine composition comprising an effective amount of antigen or a nucleic acid encoding antigen, encapsulated in polymeric particles, wherein said polymeric particles comprises nanoparticles, microparticles or combinations thereof, wher... | 05/06/2010 |
| 20100068227 | Composition Useful as a Vaccine The present invention relates to a composition comprising a viral antigen, a first protein and a second protein. Optionally, the composition also comprises three different disaccharaides, or, optionally, the composition comprises a primary sugar and at least one, prefer... | 03/18/2010 |
| 20100055131 | REOVIRUS COMPOSITIONS AND METHODS OF USE The present invention relates to novel strains of avian reovirus that were isolated from severe cases of Runting Stunting Syndrome in young broiler chickens in southeast United States. The invention is directed to avian reoviruses that impair digestion in poultry, diagn... | 03/04/2010 |
| 20100055129 | MODULATORS OF MYC, METHODS OF USING THE SAME, AND METHODS OF INDENTIFIYING AGENTS THAT MODULATE MYC Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune respons... | 03/04/2010 |
| 20100047278 | Human Rotavirus and Vaccine Composition Comprising Same Provided are G12 human rotaviruses having VP7 gene of SEQ ID NO: 1 or 2 and VP4 gene of SEQ ID NO: 3 or 4; antibodies specific for said rotaviruses; and a vaccine composition containing the same. The antibodies and the vaccine composition are effective for diagnosing ro... | 02/25/2010 |
| 20100047279 | IMMUNOLOGICAL COMPOSITION The present invention relates to immunological compositions comprising sulpholipo-cyclodextrin (SL-CD) and, saponin or Quil A, and optionally at least one antigen. The invention relates to methods and immunological compositions comprising at least one antigen, which may... | 02/25/2010 |
| 20100003279 | VACCINE FOR IN OVO INOCULATION A purpose of the present invention is to provide a vaccine for in ovo inoculation effective for prevention of any fowl viral diseases. A fowl vaccine for in ovo inoculation with high efficacy in view of safety as well wherein, by holding such live viruses on a virus-ads... | 01/07/2010 |
| 20090280142 | METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOPOROSIS A method of detecting osteoporosis in a mammalian is disclosed herein which includes:
| 11/12/2009 |
| 20090226487 | AVIAN EMBRYO PARTICULATE BIOMASS FOR THE PRODUCTION OF VIRUS ANTIGENS The present invention provides a biomass which comprises avian embryonic particles having a particle size of about 0.5 mm to 10.0 mm and the use thereof in a method for the production of virus antigens. Also provided is a method for the preparation of a vaccine useful f... | 09/10/2009 |
| 20090136545 | PORCINE ROTAVIRUS REASSORTANT COMPOSITIONS The present invention provides rotavirus reassortant immunogenic compositions based on a porcine rotavirus. In particular, porcine rotavirus Gottfried strain-based single VP7 or VP4 gene substitutions which can provide (i) an attenuation phenotype of a porcine rotavirus... | 05/28/2009 |
| 20090130145 | VACCINE The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly prov... | 05/21/2009 |
| 20090041852 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or... | 02/12/2009 |
| 20080292660 | Hexavalent Bovine Rotavirus Reassortant Composition Designed for Use in Developing Countries The present invention provides vaccine compositions for protection against human rotaviral disease designed for use in particular areas of the world. Human×bovine reassortant rotavirus comprising each of the four clinically most important VP7 serotypes of human rotavir... | 11/27/2008 |
| 20080213304 | Methods of Treating and Preventing Neurological Symptons Caused by Avian Reovirus and Novel Associated Characteristics Embodiments of the present invention generally relate to novel methods for the treatment and/or prevention of neurological symptoms caused by an avian reovirus, enteric reovirus strain (ERS), and associated characteristics. Other embodiments generally comprise and immun... | 09/04/2008 |
| 20080166372 | Live Attenuated Rotavirus Vaccine for Oral Administration This invention provides liquid rotavirus formulations that are suitable for oral administration to human infants. In particular, the invention provides pharmaceutical compositions and vaccines, comprising a rotavirus antigen, a sugar and a carboxylate, wherein said form... | 07/10/2008 |