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Patent No. 5285430

Behavior Modification Wristwatch

A wristwatch including a watch band and a watch body having an octagon shaped perimeter and being red in color and having the word STOP thereon to resemble a stop sign.

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Class 424/212.1 - Measles virus or mumps virus


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the virus is a measles virus or a
No. of applications: 30
Last issue date: 02/23/2012


Application No.Application TitleIssue Date
20120045430DENDRIMER-LIKE MODULAR DELIVERY VECTOR
Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. The nucleic acids are used to form dendrimers that are useful as supports, vectors, ca...
02/23/2012
20120039935METHODS OF TREATING MEASLES INFECTIOUS DISEASE IN MAMMALS
The invention provides for a measles vaccine utilizing a human codon-optimized polynucleotide encoding a measles virus polypeptide, such as HA or F protein. Optionally, the vaccine is administered with an adjuvant and is especially useful for immunizing an infant mammal...
02/16/2012
20110293723SYNTHETIC NANOCARRIER COMBINATION VACCINES
Disclosed are dosage forms and related methods, that include a first population of synthetic nanocarriers that have one or more first antigens coupled to them, one or more second antigens that are not coupled to the synthetic nanocarriers, and a pharmaceutically accepta...
12/01/2011
20110243988Methods and Compositions for Stabilization of a Virus Vaccine
This invention provides compositions and methods for stabilizing a live attenuated virus in dried formulations. In particular, compositions and methods of preparing a dried vaccine are provided that stabilize the viability of live vaccines such as measles and adenovirus...
10/06/2011
20110217244COMPOSITIONS AND METHODS FOR ENHANCING IMMUNE RESPONSE
The use of oxidatively transformed carotenoid or a component thereof to enhance the immune response in a subject for the treatment of infection or to enhance the immune response to an antigen in a subject being immunized. Also disclosed are pharmaceutical compositions a...
09/08/2011
20110182857Delivery of Drugs to Mucosal Surfaces
Liquid pharmaceutical compositions for administration to a mucosal surface, including a therapeutic agent and a pectin with a low degree of esterification are described. Such compositions gel, or can be adapted to gel, at the site of application in the absence of an ext...
07/28/2011
20110177120MYCOBACTERIUM TUBERCULOSIS VACCINE
The present invention relates to the use of live mycobacterium of the M. tuberculosis complex for preparing a medicament, wherein the function of the zmp1-gene is inactivated, pharmaceutical compositions prepared from such mycobacteria as well as a method for the...
07/21/2011
20110150927Stabilisation of Viral Microparticles
A micro-particulate dry powder composition comprising a viral particle can be prepared by spray-drying a mixture of the viral particle and a stabilizing carbohydrate using an outlet temperature of no more than 60° C....
06/23/2011
20110142881TRANSCUTANEOUS DELIVERY OF THERAPEUTIC AGENTS
The present invention provides materials and methods to facilitate the transcutaneous delivery of therapeutic agents. In some embodiments, agonists of tight junctions are used in compositions to facilitate the uptake of therapeutic agents from the skin. In a particular ...
06/16/2011
20110135679COMPOSITIONS FOR INDUCING IMMUNE RESPONSES
The invention provides, inter alia, immunogenic compositions that comprise (a) a first antigen, (b) at least first and second adjuvants, wherein the first adjuvant comprises microparticles and wherein the second adjuvant comprises an imidazoquinoline compound, and (c) a...
06/09/2011
20110110979METHOD AND VACCINE FOR OPTIMIZING THE SPECIFIC IMMUNE RESPONSES
The present invention relates to a method for treating an infection or disease or lesion, in particular an HPV infection. Furthermore, it relates to a vaccine for treating a Human Papillomavirus (HPV) infection or an associated disease or lesion in a subject....
05/12/2011
20110014231ANTI-MEASLES CANCER IMMUNOTHERAPY
The present invention provides methods for treating specific populations of cancer patients by immunotherapy. The methods comprise administering an immunogenic composition eliciting an immune response to measles virus to patients having measles virus-immunoreactive canc...
01/20/2011
20100285135Nanoparticles For Use In Immunogenic Compositions
Disclosed herein are sterile-filtered lyophilized nanoparticle compositions which contain at least one biodegradable polymer, at least one surfactant, at least one cryoprotective agent and at least one antigen. Also disclosed are methods of making and using such composi...
11/11/2010
20100247537ADJUVANT COMBINATIONS OF NKT ACTIVATOR, CD40 AGONIST, AND OPTIONAL ANTIGEN, THE USE THROUGH INDUCING SYNERGISTIC CELLULAR IMMUNITY
Adjuvant combinations comprising at least one NKT activator, such as alpha-galactosylceramide (α-Gal-Cer) or iGb3, a CD40 agonist and optionally an antigen are disclosed. The use of these immune adjuvants for treatment of various chronic diseases such as cancers is als...
09/30/2010
20100119548METHOD FOR LIMITING THE GROWTH OF CANCER CELLS USING AN ATTENUATED MEASLES VIRUS
A method for treating cancer cells is provided comprising directly or systemically administering a therapeutically effective dose of an attenuated measles virus. In one embodiment, the therapeutically effective dose is from about 103 pfus to about 1012 <...
05/13/2010
20100112078POLYMER PARTICLES BASED VACCINE
The present invention provides a vaccine composition comprising an effective amount of antigen or a nucleic acid encoding antigen, encapsulated in polymeric particles, wherein said polymeric particles comprises nanoparticles, microparticles or combinations thereof, wher...
05/06/2010
20100055129MODULATORS OF MYC, METHODS OF USING THE SAME, AND METHODS OF INDENTIFIYING AGENTS THAT MODULATE MYC
Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune respons...
03/04/2010
20100040650Virus-Like paramyxovirus particles and vaccines
The present invention is directed to alphavirus virus-like particles produced by synthesizing in cell, including in vivo, structural proteins in the absence of other alphavirus proteins. In particular, these virus-like particules vaccines induce cellular and humoral imm...
02/18/2010
20090297559USE OF TIGHT JUNCTION AGONISTS TO FACILITATE PULMONARY DELIVERY OF THERAPEUTIC AGENTS
The present invention provides materials and methods to facilitate the pulmonary delivery of therapeutic agents. In some embodiments, agonists of tight junctions (e.g., zonulin agonists) are used in compositions to facilitate the uptake of therapeutic agents from the pu...
12/03/2009
20090280142METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOPOROSIS
A method of detecting osteoporosis in a mammalian is disclosed herein which includes:
    • a) obtaining a sample of a bone r...
11/12/2009
20090263470Vaccine Compositions Comprising Virosomes and a Saponin Adjuvant
This invention provides virosome preparations from an enveloped virus, in particular from influenza virus, containing from said virus, and a saponin adjuvant. In particular the invention provides a virosome preparation from influenza virus an influenza antigen a QS21, o...
10/22/2009
20090214537Serum Resistance Factors of Gram Positive Bacteria
A newly identified serum resistance factor of gram positive bacteria can be used to treat or prevent bacterial infection....
08/27/2009
20090175903MEASLES SUBUNIT VACCINE
Compositions and methods for making and using therapeutic formulations of measles virus antigens with a Proteosome-based adjuvant are provided. The measles virus antigens may be derived from a variety of sources, such as from recombinant production or from a split antig...
07/09/2009
20090142362Peptide-based vaccine compositions to endogenous cholesteryl ester transfer protein (CETP)
Improved vaccine compositions and methods of use thereof are described that elicit production of antibodies in an individual to the individual's own endogenous cholesteryl ester transfer protein (CETP)....
06/04/2009
20090123367Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally activ...
05/14/2009
20090074816TISSUE TARGETED ANTIGENIC ACTIVATION OF THE IMMUNE RESPONSE TO CANCERS
The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formu...
03/19/2009
20090010964Lipid and Nitrous Oxide Combination as Adjuvant for the Enhancement of the Efficacy of Vaccines
The invention provides for a method of enhancing immunological responses to an antigen in a vaccine formulation, and for a vaccine formulation that provides for an enhanced immunological response to an antigen. In the method and formulation the antigen is administered w...
01/08/2009
20090004203METHODS OF TREATING MEASLES INFECTIOUS DISEASE IN MAMMALS
The invention provides for a measles vaccine utilizing a human codon-optimized polynucleotide encoding a measles virus polypeptide, such as HA or F protein. Optionally, the vaccine is administered with an adjuvant and is especially useful for immunizing an infant mammal...
01/01/2009
20080233149Use of Erythropoietin for Enhancing Immune Responses and for Treatment of Lymphoproliferative Disorders
The present invention relates to the use of erythropoietin (EPO) for enhancing immune responses and for the treatment of lymphoproliferative disorders, excluding multiple myeloma. Accordingly to the invention EPO may be administered with a viral or bacterial vaccine....
09/25/2008
20080124352Methods to bypass CD4+ cells in the induction of an immune response
Embodiments of the invention disclosed herein relate to methods and compositions for bypassing the involvement of CD4+ cells when generating antibody and MHC class I-restricted immune responses, controlling the nature and magnitude of the response, and promoting effecti...
05/29/2008
 
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