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| Application No. | Application Title | Issue Date |
| 20090012494 | INTRADERMAL DELIVERY OF BIOLOGICAL AGENTS The present invention relates to methods for intradermally delivering one or more biologically active agents such as vaccines and therapeutic agents into the dermis layer of the skin of a subject to obtain systemic delivery or an immune response using a microneedle drug... | 01/08/2009 |
| 20090010964 | Lipid and Nitrous Oxide Combination as Adjuvant for the Enhancement of the Efficacy of Vaccines The invention provides for a method of enhancing immunological responses to an antigen in a vaccine formulation, and for a vaccine formulation that provides for an enhanced immunological response to an antigen. In the method and formulation the antigen is administered w... | 01/08/2009 |
| 20080311106 | Product Comprising a C4bp Core Protein and a monomeric Antigen, and Its Use The invention provides a product which comprises a C4bp core protein and a monomeric antigen, desirably in the form of a fusion protein. Monomeric antigens include malarial and influenza antigens. The C4bp core protein provides for assembly of multimeric complexes of th... | 12/18/2008 |
| 20080299151 | Influenza vaccines Described herein are vaccines and the use of naked DNA and/or RNA encoding hemagglutinin (HA) from pandemic influenza, e.g., the 1918 H1N1 and/or the 1957 H2N2 and/or the 1968 H3N2 influenza A virus, as a vaccine component against present day and coming H1, H2, H3, H5, ... | 12/04/2008 |
| 20080286307 | Two-Step Temperature Profile for the Propagation of Viruses The present invention provides a method for the production of a virus. The method includes providing a host cell that has been infected by the virus and cultivating the infected host cell at two different temperatures. The virus produced by the cultivation steps is subs... | 11/20/2008 |
| 20080279926 | Vaccine Compositions Comprising a Saponin Adjuvant An immunogenic composition in a dose volume suitable for human use comprising an antigen or antigenic preparation, in combination with an adjuvant which adjuvant comprises an immunologically active saponin fraction derived from the bark of Quillaja Saponaria Moli... | 11/13/2008 |
| 20080279891 | Viral Adjuvants The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the vir... | 11/13/2008 |
| 20080274141 | ANIMAL CELLS AND PROCESSES FOR THE REPLICATION OF INFLUENZA VIRUSES Animal cells are described which can be infected by influenza viruses and which are adapted to growth in suspension in serum-free medium. Processes for the replication of influenza viruses in cell culture using these cells are furthermore described, as well as vaccines ... | 11/06/2008 |
| 20080260764 | REPLIKIN PEPTIDES AND USES THEREOF The present invention provides isolated influenza peptides and nucleic acid sequences and methods of identifying said influenza peptides and nucleic acid sequences having a pattern of substitution of amino acids or nucleic acids in highly conserved Replikin and Replikin... | 10/23/2008 |
| 20080254067 | Process for the Production of an Influenza Vaccine The present invention relates to a commercial-scale process for the production of influenza virus or antigens for prophylactic, diagnostic, immunotherapeutic or therapeutic purposes. Particularly, the invention provides a Madin-Darby Canine Kidney (MDCK)-derived, cell l... | 10/16/2008 |
| 20080241184 | CANINE INFLUENZA VACCINES The present invention encompasses influenza vaccines, in particular canine influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing influenza anti... | 10/02/2008 |
| 20080233142 | Use of penetration enhancers and barrier disruption methods to enhance the immune response of an antigen A transcutaneous immunization system where the topical application of an adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a systemic or mucosol antibody response. The immune response so elicited can be enhanced by physical or chemi... | 09/25/2008 |
| 20080233149 | Use of Erythropoietin for Enhancing Immune Responses and for Treatment of Lymphoproliferative Disorders The present invention relates to the use of erythropoietin (EPO) for enhancing immune responses and for the treatment of lymphoproliferative disorders, excluding multiple myeloma. Accordingly to the invention EPO may be administered with a viral or bacterial vaccine.... | 09/25/2008 |
| 20080233148 | Method of Producing Virus It is intended to provide a safe and efficient method of producing a virus which is free from animal-origin components in the whole process from culturing adhesive cells to producing the virus on an industrial scale by the cell culture. Namely, a method of producing a v... | 09/25/2008 |
| 20080226676 | Multivalent avian influenza vaccines and methods The present invention provides vaccine compositions comprising at least two strains of avian influenza virus, wherein one of the strains has an H5 hemagglutinin subtype and the other strain has an H7 hemagglutinin subtype, and wherein at least one of the strains has an ... | 09/18/2008 |
| 20080213309 | MULTI-ANTIGENIC ALPHAVIRUS REPLICON PARTICLES AND METHODS Viral replicon selected nucleic acid expression libraries are useful for analyzing multiple antigens associated with a parasite, pathogen or neoplasia or for preparing immunogenic compositions for generating immune responses specific for the parasite, pathogen or neopla... | 09/04/2008 |
| 20080213308 | Imidazoquinoline Compounds The invention provides novel compositions comprising imidazoquinoline compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of admini... | 09/04/2008 |
| 20080206280 | VACCINE FOR ACTIVATING HELPER FUNCTION OF CD8+ TCELLS The invention provides compositions and methods for treating or preventing a target disease in a mammal by induction of memory T cells. The methods comprise (1) administering a sensitizing composition comprising a non-target antigen to a patient; and (2) administering a... | 08/28/2008 |
| 20080206278 | Vaccine Provided herein are methods for immunizing children under six months of age by administering to the child a pharmaceutical composition comprising at least one antigen derived from an influenza virus.... | 08/28/2008 |
| 20080199495 | Stimulation of thymus for vaccination development The present disclosure provides methods for enhancing the response of a patient's immune system to vaccination. This is accomplished by reactivating the thymus. Optionally, hematopoietic stem cells, autologous, syngeneic, allogeneic or xenogeneic, are delivered to incre... | 08/21/2008 |
| 20080193412 | Method of Enhancing the Immune Response to a Vaccine A method for enhancing the immune response to an antigen or vaccine comprising administering an effective amount of a Th1 stimulatory cytokine, preferably interferon, oromucosally at substantially the same time as administration of an effective amount of an antigen or v... | 08/14/2008 |
| 20080187546 | Method for Replicating Influenza Virus in Culture The invention is related to a method for selecting an influenza virus for growth on tissue culture cells to produce a tissue-culture adapted viral isolate. The invention also includes vaccines produced from the isolate.... | 08/07/2008 |
| 20080181914 | NOVEL VACCINE COMPOSITION An inactivated influenza virus preparation is described which comprises a haemagglutinin antigen stabilised in the absence of thiomersal, or at low levels of thiomersal, wherein the haemagglutinin is detectable by a SRD assay. The influenza virus preparation may compris... | 07/31/2008 |
| 20080175863 | METHODS AND COMPOSITIONS FOR INCREASING REPLICATION CAPACITY OF AN INFLUENZA VIRUS In certain aspects, the present invention provides methods for increasing the replication capacity of influenza viruses in hens' eggs and/or cell culture, recombinant and/or reassortant influenza viruses with increased replication capacity, and immunogenic and vaccine c... | 07/24/2008 |
| 20080171063 | Novel Composition The present invention relates to influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation. In particu... | 07/17/2008 |
| 20080166348 | Uses and compositions for treatment of rheumatoid arthritis The invention provides methods, uses and compositions for the treatment of rheumatoid arthritis. The invention describes methods and uses for treating rheumatoid arthritis wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof. Als... | 07/10/2008 |
| 20080145383 | Method for Solubilizing Peptide Mixtures Described is a method for making a pharmaceutical preparation comprising the solubilisation of a peptide mixture, characterized in that the peptide mixture is solubilized by an aqueous solution containing at least one organic acid selected from the group consisting of f... | 06/19/2008 |
| 20080118531 | AVIAN INFLUENZA VIRUSES, VACCINES, COMPOSITIONS, FORMULATIONS, AND METHODS A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection is set forth herein. The vaccine contains at least two inactivated strains of avian influenza virus, wherein the combined hemagglutinin (HA) total is at lea... | 05/22/2008 |
| 20080112972 | PRESERVATION OF BIOACTIVE MATERIALS BY FREEZE DRIED FOAM This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes.... | 05/15/2008 |
| 20080107687 | FELINE VACCINES AGAINST AVIAN INFLUENZA The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing avian influenza... | 05/08/2008 |
| 20080075736 | Materials and methods for respiratory disease control in canines The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the... | 03/27/2008 |
| 20080014217 | INFLUENZA VACCINE The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in medicine, in particular their use in augmenting immune responses to various antigens, and to methods of preparation.... | 01/17/2008 |
| 20070224220 | Intranasal or inhalational administration of virosomes The present invention provides a composition of influenza virosomes comprising reconstituted envelopes of said virus, wherein the viral envelopes are entirely derived from influenza viral particles, wherein no lipid is added from an external source to the reconstituted ... | 09/27/2007 |
