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| Application No. | Application Title | Issue Date |
| 20120014837 | ILLUMINATION OF INTEGRATED ANALYTICAL SYSTEMS An analytical device including an optically opaque cladding, a sequencing layer including a substrate disposed below the cladding, and a waveguide assembly for receiving optical illumination and introducing illumination into the device. The illumination may be received ... | 01/19/2012 |
| 20110306143 | Apparatus for single-molecule detection An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus fur... | 12/15/2011 |
| 20110236266 | OPTICAL SENSOR According to one embodiment, an optical sensor includes an optical waveguide module and a specimen area. The specimen area is provided adjacent to the optical waveguide module, and is configured to hold a specimen. The specimen area includes a sensing area and a precipi... | 09/29/2011 |
| 20110142718 | GLUCOSE SENSOR CHIP According to one embodiment, a glucose sensor chip includes an optical waveguide layer on a main surface of a substrate, the optical waveguide layer including a pair of gratings which are separated each other, a sensing film on a surface of a portion of the optical wave... | 06/16/2011 |
| 20100278697 | METHODS AND SYSTEMS FOR DETECTING BIOMOLECULAR BINDING USING TERAHERTZ RADIATION Provided herein are methods and systems for detecting biomolecular binding events using gigahertz or terahertz radiation. The methods and systems use low-energy spectroscopy to detect biomolecular binding events between molecules in an aqueous solution. The detected bio... | 11/04/2010 |
| 20100278696 | BIOSENSOR It is an object of the present invention to provide a biosensor having excellent preservation stability. The present invention provides a biosensor wherein a first hydrophilic polymer layer is immobilized on a self-assembled membrane applied onto the surface of a metal ... | 11/04/2010 |
| 20100215545 | BIOCHEMICAL MEASURING DEVICE A fiber switching mechanism of a lighting system for passing a light through one of n optical fibers corresponding to n channels sequentially is provided midway in n optical fibers of the lighting system corresponding to n channels such that lights from n optical fibers... | 08/26/2010 |
| 20100196207 | STRUCTURES FOR CONTROLLING LIGHT INTERACTION WITH MICROFLUIDIC DEVICES Systems and methods for improved measurement of absorbance/transmission through fluidic systems are described. Specifically, in one set of embodiments, optical elements are fabricated on one side of a transparent fluidic device opposite a series of fluidic channels. The... | 08/05/2010 |
| 20100190269 | DEVICE, SYSTEM AND METHOD OF DETECTING TARGETS IN A FLUID SAMPLE The present invention provides a biochemical detection system that comprises an exchangeable cartridge unit with light guiding tubes pre-coated with capture agent(s) and an optical detection unit. Upon flowing the liquid or gaseous sample containing the target(s) throug... | 07/29/2010 |
| 20100144052 | Optical Molecular Detection Optical detection of molecules using a biochip having at least one reagent immobilizing area designed to receive one or more reagents and at least one calibration structure with a predetermined height to provide a height reference for optical measurement is disclosed. W... | 06/10/2010 |
| 20100124787 | CAVITY-ENHANCED ON-CHIP ABSORPTION SPECTROSCOPY Embodiments of optofluidic devices or methods according to the application can provide on-chip, label-free, massively parallel analysis of analytes. An embodiment of the optofluidic device can comprise a microresonator, a waveguide optically coupled to the microresonato... | 05/20/2010 |
| 20100098592 | POROUS MEMBRANE WAVEGUIDE SENSORS AND SENSING SYSTEMS THEREFROM FOR DETECTING BIOLOGICAL OR CHEMICAL TARGETS A sensor for sensing at least one biological target or chemical target is provided. The sensor includes a membrane includes a membrane material that supports generation and propagation of at least one waveguide mode, where the membrane material includes a plurality of v... | 04/22/2010 |
| 20100055666 | BIOSENSOR WITH EVANESCENT WAVEGUIDE AND INTEGRATED SENSOR The present invention is directed to a waveguide sensor as well as to an evanescent field induced evanescent field induced sensor system for use in diagnostic housing and an integrated waveguide sensor comprising: a waveguide layer,—capture compounds applied on the up... | 03/04/2010 |
| 20090311717 | MICROFLUIDIC CHIP DESIGN COMPRISING CAPILLARIES The invention provides a microfluidic device wherein capillaries are connected to the microfluidic device by a deformable penetrable substance.... | 12/17/2009 |
| 20090304551 | Ultra Sensitive Tapered Fiber Optic Biosensor For Pathogens, Proteins, and DNA A biconically tapered optical fiber serves as a biosensor at all optical wavelengths of interest ranging from UV to far IR at subfemtogram per mL sensitivity. The biconically tapered sensor detects biomaterials such as pathogenic species, proteins and DNA and others bio... | 12/10/2009 |
| 20090269244 | Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers An apparatus and method for detection of peak wavelength values of colorimetric resonant optical biosensors using tunable filters and tunable lasers is provided. Biomolecular interactions may be detected on a biosensor by directing collimated white light towards a surfa... | 10/29/2009 |
| 20090269836 | Apparatus and Method for Analysing a Biological Sample in Response to Microwave Radiation Apparatus and method of exposing a chemical, biological or biochemical sample to radiation. A sample in liquid or vapour phase is segmented and conveyed along a sample path. At least one generator or source for generating electromagnetic radiation is directed at the sam... | 10/29/2009 |
| 20090263912 | NANOWIRES AND NANORIBBONS AS SUBWAVELENGTH OPTICAL WAVEGUIDES AND THEIR USE AS COMPONENTS IN PHOTONIC CIRCUITS AND DEVICES A microfluidic optical sensor utilizes at least one subwavelength nanowire or nanoribbon waveguide coupled to a fluidic structure having at least one nanofluidic channel through which one or more molecular species are conveyed. In response to optical pumping (e.g., a la... | 10/22/2009 |
| 20090252649 | Apparatus for body fluid analysis using surface-textured optical materials A variety of characteristics of body fluid may be measured by introducing a sample to a textured surface on optical material such as waveguides and sheets. The textured surface presents a field of elongated projections which are spaced apart to exclude certain component... | 10/08/2009 |
| 20090124024 | OPTICAL-WAVEGUIDE SENSOR CHIP, METHOD OF MANUFACTURING THE SAME, METHOD OF MEASURING SUBSTANCE, SUBSTANCE-MEASURING KIT AND OPTICAL-WAVEGUIDE SENSOR An optical-waveguide sensor chip includes an optical waveguide having a first substance immobilized on the surface thereof, the first substance being specifically reactive with an analyte substance, and fine particles dispersed on the optical waveguide and having a seco... | 05/14/2009 |
| 20090117600 | Detection of biological molecules by differential partitioning of enzyme substrates and products This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biological sa... | 05/07/2009 |
| 20090081808 | DEVICE AND METHOD FOR IDENTIFYING MYCOTOXINS The invention relates to an apparatus and a process for detection of mycotoxins and to kits suitable for carrying out said process.... | 03/26/2009 |
| 20090068668 | Waveguide-Based Optical Scanning Systems A scanning sensor system, methods of use and kits for detecting a biologically active analyte are provided. The scanning sensor system includes a light source, a detector, a substrate comprising a plurality of waveguides and a plurality of optical sensing sites in optic... | 03/12/2009 |
| 20090035872 | FLUIDICS SYSTEM The present invention provides a fluidics system and a method for selectively drawing fluid from at least one selected reservoir into a channel by providing a negative pressure source downstream of the fluid and channel and selectively back filling the selected reservoi... | 02/05/2009 |
| 20080299008 | Flow cell array and the utilization thereof for multianalyte determination A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (... | 12/04/2008 |
| 20080176317 | System and device for transformation and detection of substances A system and method for transformation of at least one harmful analyte that is difficult to detect to a substance or substances that are more readily detectable by a detector unit and includes parts and steps for detection and quantification of a target analyte or a plu... | 07/24/2008 |
| 20080085552 | Systems and methods for measurement optimization The invention relates to methods and systems for detecting and or analyzing an agent in a sample with a chip having optical components incorporated therein. ... | 04/10/2008 |
| 20080063569 | System and method for self-referencing a sensor in a micron-sized deep flow chamber A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel. ... | 03/13/2008 |
| 20080056950 | DEVICE FOR THE DETECTION OF FLUORESCENCE EMITTED BY CHROMOPHORIC ELEMENTS IN THE WELLS OF A MULTIWELL PLATE A device for detecting the fluorescence emitted by chromophore elements contained in the wells of a multiwell plate, the device comprising means integrated in the transparent bottoms of the wells of the plate to limit the penetration length in the wells of a light beam ... | 03/06/2008 |
| 20080026476 | Device and Method for Detecting Blood Coagulation A device is provided for use with a reader for determining coagulation of a sample of biological fluid. The device comprises a structure having an at least one chamber for containing a sample of biological fluid. A coagulation reagent capable of interacting with the flu... | 01/31/2008 |
| 20080020480 | Multiwell Plates with Integrated Biosensors and Membranes The invention provides compositions and methods of detecting binding of molecules to a biosensor. Compositions of the invention comprise a multiwell plate with an integrated biosensor and a membrane. ... | 01/24/2008 |
| 20070211985 | Optical Scanning System A scanning sensor system 100, methods and kits for use thereof including a switchable light source 102, a detector 106, a substrate 104 and a plurality of optical sensing sites 112 are provided. Substrate 104 is coupled to and i... | 09/13/2007 |
| 20070148047 | Sensor for analyzing or identifying property of object, sensing apparatus using same, and sensing method A sensor is provided which comprises a waveguide for allowing an electromagnetic wave to propagate therethrough and disposing an object at a plurality of positions thereof, and a detecting portion for detecting the electromagnetic wave which has interacted with the obje... | 06/28/2007 |
| 20070122311 | High performance materials for optical sensors for hydrocarbons environment This invention belongs to the field of optical chemical sensors. Specifically, it relates to sensors based on the absorbance and emission of light by an indicator molecule where the optical properties of the indicator molecule change in response to a particular analyte.... | 05/31/2007 |
| 20070071649 | Capillary-channeled polymer fibers as stationary phase media for spectroscopic analysis Surface-channeled fibers, either single fibers or a plurality of fibers, and surface-channeled films are useful in a variety of on-column detection systems, both those requiring detection by a spectroscopic detector and those for which a chemically selective indicator p... | 03/29/2007 |
| 20070059211 | TNT sensor containing molecularly imprinted sol gel-derived films The invention relates to a chemically-sensitive film for use in a detector for TNT, where the chemically sensitive film includes a porous, polymeric structure and a plurality of basic functional groups integral with the porous, polymeric structure, and the basic functio... | 03/15/2007 |
| 20070014692 | Method and apparatus for measurement of binding between a protein and a nucleotide A method and apparatus for measuring binding between a plurality of molecules of a first type and a plurality of molecules of a second type is presented. Apparatus utilizes a sensor possessing a waveguide to which have been attached in close proximity to its surface, fe... | 01/18/2007 |
| 20060228260 | Optical analysis device An optical analysis device comprises a lighttransmitting member for transmitting light, having an external face capable of immobilizing a detectionobjective substance, a light separating means for separating an exciting light introduced into the light-transmitting membe... | 10/12/2006 |
| 20060211126 | Method for using texturing surfaces of optical fiber sensors for blood glucose monitoring Disclosed is a method and the resulting product thereof comprising a solid light-conducting fiber with a point of attachment and having a textured surface site consisting a textured distal end prepared by being placed in a vacuum and then subjected to directed hyperther... | 09/21/2006 |
| 20060210440 | Opto-acoustic sensor system and associated method A system that includes a device is provided in which the device includes a piezoelectric substrate; a sensor layer disposed on the substrate and operable to interact with, or react with, a target species; a first and a second electrode that are spaced from each other an... | 09/21/2006 |
