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| Application No. | Application Title | Issue Date |
| 20120107950 | MEASUREMENT SYSTEM FOR FLUORESCENT DETECTION, AND METHOD THEREFOR In one aspect, the invention provides a measurement system, wherein the measurement system comprises a sample module to receive a sample, wherein the sample module comprises at least one fluorophore; an optics module to generate an incident beam to impinge on the sample... | 05/03/2012 |
| 20120045846 | SYSTEM AND METHOD FOR pH FORMULATIONS A system and method for creating a buffer solution having a desired pH value is disclosed. The method uses two known buffer solutions, each with predetermined pH values, and determines a mathematical relationship which defines the amount of each known buffer solution ne... | 02/23/2012 |
| 20120045841 | SYSTEM AND METHOD FOR GENERATION OF AUTOMATED DENATURATION GRAPHS A system and method for creating a plurality of denaturation curves is disclosed. In accordance with certain embodiments, one variable, such as salt content, pH or another parameter, is varied to create a plurality of different buffer solutions. Each is then used to cre... | 02/23/2012 |
| 20120034701 | DEVICE FOR ASSAY OF A LIQUID SAMPLE Device and detection system comprising two polarising elements and a measuring zone located between said polarising elements, wherein the measuring zone is being bounded on one side by the first polarising element. The device further comprises an inlet reservoir, an out... | 02/09/2012 |
| 20120034702 | METHOD AND APPARATUS FOR MEASURING FLUORESCENCE IN LIQUIDS A method of measuring the fluorescence of a fluorescent marker compound dissolved or dispersed in a bulk material includes: (a) measuring a characteristic of the fluorescence of a mixture of said bulk material and said fluorescent marker compound; (b) quenching the fluo... | 02/09/2012 |
| 20120027642 | Luminometer or Fluorometer with an Injection Device Described is a luminometer or fluorometer having an optical axis which extends essentially perpendicular to the measuring sample. The detector for the luminometer or the fluorometer is arranged either directly or via a deflection means in the optical axis. An injection ... | 02/02/2012 |
| 20120028849 | MICROWAVE ACCELERATED ASSAYS The present invention provides for increasing fluorescence detection in surface assay systems while increasing kinetics of a bioreaction therein by providing low-power microwaves to irradiate metallic materials within the system in an amount sufficient to increase heat ... | 02/02/2012 |
| 20120021443 | DIRECTIONAL SURFACE PLASMON COUPLED FLUORESCENCE AND CHEMILUMINESCENCE FROM THIN FILMS OF NICKEL, IRON OR PALLADIUM AND USES THEREOF Nickel, iron and palladium thin films thermally evaporated onto glass supports are used to demonstrate surface plasmon coupled fluorescence (SPCF) and surface plasmon couple chemiluminescence (SPCC) over a broad wavelength range (400-800 nm) for potential assays or othe... | 01/26/2012 |
| 20120021525 | OPTICS COLLECTION AND DETECTION SYSTEM AND METHOD Optics collection and detection systems are provided for measuring optical signals from an array of optical sources over time. Methods of using the optics collection and detection systems are also described.... | 01/26/2012 |
| 20120015445 | Portable Fluorimetric Apparatus, Method and System A fluorimetric system, apparatus and method are disclosed to measure an analyte concentration in a sample. A sensor reagent housing is also disclosed which comprises a channel and a porous medium having an analysis chemistry reagent, such as a nucleic acid analysis chem... | 01/19/2012 |
| 20120015444 | Sensor Housing and Reagent Chemistry A sensor comprises a sensor housing, having a channel; a porous substrate, in the channel; an analysis chemistry reagent, on the porous substrate; and a nozzle, in fluid connection with the channel. The porous substrate fills a cross section of the channel, and the cros... | 01/19/2012 |
| 20120009088 | HIGH-PERFORMANCE LIGHT SOURCE APPARATUS FOR FLUORESCENCE PHOTOGRAPHY A high-performance light source apparatus for fluorescence photography of biomolecule sample gels is disclosed. The high-performance light source apparatus comprises a base frame, a supporting region located on the center of the top surface of the base frame for support... | 01/12/2012 |
| 20110312753 | LOC WITH INTEGRAL LED DRIVER FOR EXCITATION LED A microfluidic device having a supporting substrate, a probe with a nucleic acid sequence for hybridization with a target nucleic acid sequence to form a probe-target hybrid and generate a fluorescence signal in response to an excitation light, and, CMOS circuitry on th... | 12/22/2011 |
| 20110312610 | TEST MODULE WITH LONG FLUORESCENCE LIFETIME PROBES A test module having an outer casing dimensioned for hand-held portability, the outer casing having an inlet for receiving a biological sample containing a target nucleic acid sequence, and, probes in the outer casing for hybridization with the target nucleic acid seque... | 12/22/2011 |
| 20110312541 | LOC FOR DETECTION OF HYBRIDIZATION OF NUCLEIC ACID SEQUENCES WITH PRIMER-LINKED LINEAR PROBES A LOC device having a supporting substrate, a primer-linked, linear probe with a nucleic acid sequence that matches a target nucleic acid sequence, and a primer for elongating against the target nucleic acid sequence to form a complementary sequence such that during use... | 12/22/2011 |
| 20110312790 | MICROFLUIDIC TEST MODULE WITH LOW-VOLUME HYBRIDIZATION CHAMBER A microfluidic test module having an outer casing having an inlet for receiving a biological sample containing a target nucleic acid sequence, and, a hybridization chamber mounted in the casing, the hybridization chamber containing probes having a nucleic acid sequence ... | 12/22/2011 |
| 20110312570 | MICROFLUIDIC DEVICE FOR DETECTING TARGET NUCLEIC ACID SEQUENCES WITH PROBES HAVING LONG FLUORESCENCE LIFETIME FLUOROPHORES A microfluidic device for detecting a target nucleic acid sequence, the microfluidic device having a probe for hybridization with the target nucleic acid sequence to form a probe-target hybrid, the probe having a fluorophore for generating fluorescence emissions in resp... | 12/22/2011 |
| 20110305600 | MICROCHIP SOLUTION SENDING SYSTEM [Technical Problem] It is an object to provide a microchip solution sending system that is provided with the high reaction efficiency and the high detection accuracy. [Solution of Problem] | 12/15/2011 |
| 20110306143 | Apparatus for single-molecule detection An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus fur... | 12/15/2011 |
| 20110306120 | ASSAY DEVICE AND METHODS The present invention relates to the use of amphipathic polymers to enhance lateral flow and reagent mixing on assay devices. More specifically, the invention relates to use of an amphipathic polymer in assay methods including a device for determining the concentration ... | 12/15/2011 |
| 20110294997 | METAL ENHANCED FLUORESCENCE-BASED SENSING METHODS The present invention relates to metallic-surface detection systems for determining target substances including free bilirubin in neonatal serum in the presence of a predominantly high background of bilirubin bound Human Serum Albumin (HSA) or sensing and isolating targ... | 12/01/2011 |
| 20110294222 | LEAD ASSAY Process for metering lead in a sample of original water, in which is placed a sample of the water of which at least a substantial portion of the colloidal and organic material is passed in solution (sample of pretreated water), having: a first stage, starting from a sam... | 12/01/2011 |
| 20110269243 | SYSTEMS AND METHODS RELATED TO OPTICAL NANOSENSORS COMPRISING PHOTOLUMINESCENT NANOSTRUCTURES Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described.... | 11/03/2011 |
| 20110262307 | MICROFLUIDIC DEVICE AND METHOD FOR FABRICATING THE MICROFLUIDIC DEVICE The present application is directed to a technological platform with integrated microfluidic and optical modules for bio-detection. The platform enables in-situ detection by integrating fluidics with optical source and detection capabilities within a fabricated microchi... | 10/27/2011 |
| 20110262919 | METHOD FOR PRETREATING SPECIMEN AND METHOD FOR ASSAYING BIOLOGICAL SUBSTANCE On magnetic particles serving as a first support, an antibody against a nonspecific reaction factor is immobilized. These magnetic particles are mixed with a specimen and suspended therein. After suspending, the suspension is sucked up into a pipette chip and a magnet c... | 10/27/2011 |
| 20110263043 | Scanning Analyzer for Single Molecule Detection and Methods of Use The invention encompasses analyzers and analyzer systems that include a single molecule analyzer, methods of using the analyzer and analyzer systems to analyze samples, either for single molecules or for molecular complexes. The single molecule uses electromagnetic radi... | 10/27/2011 |
| 20110244598 | Test Element Having Combined Control and Calibration Zone A test element, for example in the form of an immunological test strip functioning according to the sandwich principle, for the fluorophoric detection of one or more analytes in a sample comprising an analyte detection zone and a combined control and calibration zone. T... | 10/06/2011 |
| 20110236988 | FLUORESCENT pH DETECTOR SYSTEM AND RELATED METHODS Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.... | 09/29/2011 |
| 20110236989 | ANTIOXIDANT PROTECTION OF A CHEMICAL SENSOR Analyte sensors having antioxidant protection are disclosed. By combining antioxidant and/or scavenger agents into polymer matrices that contain sensor moieties, the sensor moieties are protected from reactive oxygen species. Also disclosed are methods of making analyte... | 09/29/2011 |
| 20110236983 | SINGLE MOLECULE DETECTION AND SEQUENCING USING FLUORESCENCE LIFETIME IMAGING A nucleic acid detection system and method are provided, in which excitation energy is transmitted from a pulsed excitation source to a reaction site including a fluorescence resonance energy transfer (FRET)-based dye system to generate a fluorescent signal at the react... | 09/29/2011 |
| 20110217207 | ANALYSIS TOOL, IDENTIFICATION APPARATUS, AND ANALYSIS APPARATUS A technique is provided, which makes it possible to easily judge whether or not an analysis tool to be used for an analysis process for a sample is authentic and which makes it possible to secure the reliability of an analysis result thereby. An identification apparatus... | 09/08/2011 |
| 20110217698 | METHOD TO IMPROVE SINGLE MOLECULE ANALYSES The quality of information from single molecule analyses is improved by employing a method in which a single molecule reaction carried out within an optical confinement is monitored, the single molecule reaction is halted, and data from the optical confinement is obtain... | 09/08/2011 |
| 20110212859 | RADIO FREQUENCY IDENTIFIERS FOR USE IN BIOLOGICAL SCIENCE Provided herein are biological research methods, kits, and products that utilize radio frequency identifier technology.... | 09/01/2011 |
| 20110200989 | SINGLE MOLECULE NUCLEIC ACID SEQUENCING USING MULTIPHOTON FLUORESCENCE EXCITATION A system for detection of nucleic acids can include an excitation source configured to transmit excitation energy to a reaction site including a single molecule of nucleic acid reacted with a two-photon absorption moiety. The system also can include an optical system co... | 08/18/2011 |
| 20110201909 | ANALYTE DETECTION DEVICES AND METHODS WITH HEMATOCRIT-VOLUME CORRECTION AND FEEDBACK CONTROL Disclosed are devices, arrangements and methods for quantifying the concentration of an analyte present in bodily fluid, including: an assay pad having at least one chemical reagent capable of producing a detectable signal in the form of a reaction spot upon reaction wi... | 08/18/2011 |
| 20110200529 | ACTIVATABLE BIOLUMINESCENT PROBE SYSTEM AND METHOD OF USE THEREOF A method of use of an activatable bioluminescent probe system includes: providing a bioluminescent protein and a quencher in a reaction environment; modifying a ligand between the quencher and the bioluminescent protein using a ligand interacting molecule; adding a biol... | 08/18/2011 |
| 20110195522 | ASSAY FOR GENERATION OF A LIPID PROFILE USING FLUORESCENCE MEASUREMENT The present invention relates to a method of generating a lipid profile for a sample solution. The method comprising: a first step of determining the concentration of total lipoprotein in a first aliquot of the sample using fluorescence analysis; a second step of determ... | 08/11/2011 |
| 20110195516 | WIRE GRID SUBSTRATE STRUCTURE AND METHOD FOR MANUFACTURING SUCH A SUBSTRATE The present invention relates to a multi-layered substrate structure comprising at least one carrier layer (11), a first layer (12), said carrier layer and first layer being in contact with each other, and at least one second layer with a chemical composit... | 08/11/2011 |
| 20110177586 | DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.... | 07/21/2011 |
| 20110175982 | METHOD OF FLUORESCENT NANOSCOPY An analysis of an object dyed with fluorescent coloring agents carried out with the aid of a fluorescent microscope which is modified for improved resolving power and called a nanoscope. The method is carried out with a microscope having an optical system for visualizin... | 07/21/2011 |
