...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Application No. | Application Title | Issue Date |
| 20120071738 | METHODOLOGY AND EQUIPMENT OF OPTICAL ROTATION MEASUREMENTS A small-size optical rotation measuring device for detecting an organism, a tissue, blood, or molecules having rotatory power and determining the content thereof with high accuracy and an optical rotation measuring method for detecting an organism, a tissue, blood, or m... | 03/22/2012 |
| 20120031841 | Device and method for measuring a blood constituent in blood for an extracorporeal blood treating device The invention relates to a device and a method for measuring a blood constituent in blood for an extracorporeal blood treatment device, comprising a dialyzer or a filter, and a hose line system comprising hose lines that are pervious to electromagnetic radiation. The ki... | 02/09/2012 |
| 20120021456 | METHOD AND APPARATUS FOR DETECTING THE PRESENCE OF ANISOTROPIC CRYSTALS AND HEMOZOIN PRODUCING PARASITES IN LIQUID BLOOD An apparatus and method for detecting the presence of anisotropic crystals within a biologic fluid sample is provided. The method includes the steps of: a) disposing the sample within a sample chamber in a sample layer having a height riot greater than about fifteen mic... | 01/26/2012 |
| 20120008130 | CORRELATION TECHNIQUE FOR ANALYSIS OF CLINICAL CONDITION The present invention provides a correlation technique for analysis of changes in bodily fluid and/or tissue in order to identify or monitor appearance, progression or treatment of a disease or condition in a subject. The disclosed method involves measuring spectral pro... | 01/12/2012 |
| 20110263955 | Internal Observation Device for Object having Light Scattering Properties, Internal Body Observation Device, Endoscope for Internal Observation and Internal Observation Method There is provided an inside observation apparatus of an endoscope and the like which can perform an inside observation for irradiating an illumination light to a minute area of a surface of an object (for example, a living tissue) having a light scattering property and ... | 10/27/2011 |
| 20110216309 | COMPONENT MEASUREMENT APPARATUS A component measurement apparatus includes a confocal optical system including a laser emitting laser light, a collimating lens collimating the laser light emitted from the laser, an objective lens condensing the collimated light having exited the collimating lens in or... | 09/08/2011 |
| 20110216308 | COMPONENT MEASUREMENT APPARATUS A component measurement apparatus includes a laser that emits non-collimated laser light, an objective lens that condenses the non-collimated laser light emitted from the laser in order for the laser light to illuminate internal tissue of an object of measurement withou... | 09/08/2011 |
| 20110109897 | MEASURING APPARATUS An apparatus comprising at least one measuring cell (10) is disclosed. The measuring cell comprises a first cavity (16 and a second cavity (18) perpendicular to the first cavity, the first cavity and the second cavity comprising an overlap at first ... | 05/12/2011 |
| 20110102768 | METHOD OF DETERMINING GLUCOSE CONCENTRATION OF A WHOLE BLOOD SAMPLE A total transmission spectroscopy system for use in determining the analyte concentration in a fluid sample comprises a sample cell receiving area, a light source, a collimating lens, a first lens, a second lens, and a detector. The sample cell receiving area is adapted... | 05/05/2011 |
| 20110102769 | Small angle light scattering assay system and method for detecting malaria infection Differences between a control profile of light scattered by a control sample from a sample of whole blood and a detection profile of light scattered from a detection sample from the sample of whole blood with a detection agent added indicate malaria infection of the who... | 05/05/2011 |
| 20110076199 | DEVICE FOR THE PHOTOMETRIC EXAMINATION OF SAMPLES A device for the photometric examination of samples has a sample-holder apparatus for at least two sample vessels, and a measuring apparatus and a moveable apparatus. The sample-holder apparatus is designed to be stationary, and the measuring apparatus is arranged on th... | 03/31/2011 |
| 20110026009 | Surface Mapping by Optical Manipulation of Particles in Relation to a Functionalized Surface Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical spec... | 02/03/2011 |
| 20110023575 | NON-INVASIVE SENSOR CALIBRATION DEVICE A calibration device according to embodiments of the disclosure is capable of being used with a non-invasive sensor. Certain embodiments of the calibration device simulate a human pulse by varying the volume of blood being measured by the optical sensor. Further, embodi... | 02/03/2011 |
| 20100309454 | SPECTROMETERS MINIATURIZED FOR WORKING WITH CELLULAR PHONES AND OTHER PORTABLE ELECTRONIC DEVICES Based on the present invention, superior compact spectrometers may be constructed and integrated into a cellular phone, or attached to a cellular phone. Such a cellular phone may be a PDA phone, which supplies electrical power to the said spectrometer, provided with dat... | 12/09/2010 |
| 20100294950 | MEASURING APPARATUS, AND LIQUID COLLECTING AND MEASURING SYSTEM HAVING THE SAME A blood collecting apparatus includes a main flow path and a pressure generator. The pressure generator is provided in an intermediate position of the main flow path to insert a gas as separators at designated predetermined intervals, thereby to take out blood to be mea... | 11/25/2010 |
| 20100259747 | SAMPLE DETECTOR AND MEASUREMENT DEVICE EQUIPPED WITH THE SAME A sample detector B includes a member 6 provided with an aperture 60, as well as a light receiving element 5 which receives two light beams directed from a pair of light sources 40, 41 to a detection area AR and having passed through the dete... | 10/14/2010 |
| 20100245803 | BLOOD SAMPLE HOLDER FOR SPECTROSCOPIC ANALYSIS Some embodiments of the invention provide one sample holder that is suitable for collection and spectroscopic measurement of a blood sample. In some very specific embodiments, the sample holder is provided with an optical chamber that is specifically designed to spread ... | 09/30/2010 |
| 20100241357 | Single-Cell Raman Spectroscopy for the Non-Destructive, Non-Invasive Analysis of Cells and Cellular Components Raman spectra of cells, such as normal human T- and B-cells from peripheral blood or human tonsil and the corresponding transformed cells are obtained by optically trapping the cells and obtaining their Raman spectra. The trapped cells can be subjected to one, two, or m... | 09/23/2010 |
| 20100232675 | BLOOD AND CELL ANALYSIS USING AN IMAGING FLOW CYTOMETER Multimodal or multispectral images of cells comprising a population of cells are simultaneously collected. Photometric and/or morphometric image features identifiable in the images are used to identify differences between first and second populations of cells. The diffe... | 09/16/2010 |
| 20100220312 | BLOOD EXAMINATION APPARATUS This blood examination apparatus examines cancer cells mixed in an examination object which is flowing blood, and includes: a flow cell through which the examination object is made to flow; an imaging optical system which light output from the examination object in an e... | 09/02/2010 |
| 20100201968 | METHOD AND APPARATUS FOR PERFORMING OPTICAL MEASUREMENTS OF A MATERIAL A method of determining an optical parameter or function thereof for a liquid, the method comprising: flowing the liquid through a flow cell; transmitting a pulse of light into the liquid in the flow cell; generating a signal responsive to energy that the material emits... | 08/12/2010 |
| 20100177300 | MEASURING DEVICE A measuring device includes a VCSEL of a first-order or high-order single mode emitting laser beams, a driving part configured to drive the VCSEL, a detecting part configured to detect an electric signal relating to feedback lights generated when laser beams are project... | 07/15/2010 |
| 20100165324 | RAMAN SPECTROSCOPIC MONITORING OF HEMODIALYSIS Spectroscopic systems and methods are disclosed for determining levels of at least one analyte in blood undergoing hemodialysis. In one aspect, the invention employs Raman spectroscopy to monitor and/or control hemodialysis. In one embodiment, the system uses a laser li... | 07/01/2010 |
| 20100165325 | OPTICAL SYSTEM FOR A PARTICLE ANALYZER AND PARTICLE ANALYZER USING SAME A compact optical system for a particle analyzer and particle analyzer using same are provided. The optical system for a particle analyzer of the present invention comprises a light source, an irradiation optical system for irradiating particles passing through a flow c... | 07/01/2010 |
| 20100110415 | Analyzer and analytic system This analyzer comprises a photoirradiation portion simultaneously photoirradiating a plurality of storage vessels storing a plurality of measurement samples respectively and a plurality of photodetection portions detecting a plurality of light components resulting from ... | 05/06/2010 |
| 20100066996 | Sample analyzer The present invention is to present a sample analyzer, comprising: an imaging device for imaging a sample container which has translucency and contains a sample; a measuring device for aspirating the sample contained in the sample container and measuring the aspirated s... | 03/18/2010 |
| 20100026986 | Method and Apparatus for Separating A Composite Liquid Into At Least Two Components And For Determining The Yield Of At Least One Component Method and Apparatus for predicting the yield of a selected cellular component from a composite blood product by sensing the movement of the separated cellular component or another component during expression from a separation container to a collection container to prod... | 02/04/2010 |
| 20100030042 | METHOD AND DEVICE FOR DETERMINING OXYGEN SATURATION OF HEMOGLOBIN, FOR DETERMINING HEMATOCRIT OF BLOOD, AND/OR FOR DETECTING MACULAR DEGENERATION A method and device for accurately determining oxygen saturation of hemoglobin by the measurement of the optical density of a sample, such as a blood vessel, in response to illumination by light having at least three wavelengths (λi, λ2, λ3, . . . ) within a range of... | 02/04/2010 |
| 20100020308 | Transducer Module Transducer modules for use in a blood analysis instrument and methods for analyzing a blood sample. The transducer modules presented generally include a light source, a focus-alignment system, a flow cell, and a light scatter detection system. Electrodes within the flow... | 01/28/2010 |
| 20100014068 | MINIATURIZED CYTOMETER FOR DETECTING MULTIPLE SPECIES IN A SAMPLE A system for scattered light and simultaneous multi-color (e.g., greater than sixteen colors) fluorescence light detecting, and for analyzing, classifying and identifying biological particles and items of interest. A sample to be tested may be entered in a disposable mi... | 01/21/2010 |
| 20090310122 | BLOOD ANALYZER, SAMPLE ANALYZER, AND FLOW CYTOMETER A sample analyzer is provided that is capable of eliciting sufficient performance of an avalanche photodiode, and performing high-precision analysis of the sample. The sample analyzer is provided with a WBC detection section that uses the avalanche photodiode as a photo... | 12/17/2009 |
| 20090303462 | Correlation technique for analysis of clinical condition The present invention provides a correlation technique for analysis of changes in bodily fluid and/or tissue in order to identify or monitor appearance, progression or treatment of a disease or condition in a subject. The disclosed method involves measuring spectral pro... | 12/10/2009 |
| 20090289182 | Biomarkers of ionizing radiation The present invention provides novel radiation associated markers. The radiation associated markers may be one or more of albumin, LTGF-β, or any protein or peptide listed in any one of Tables 1, 2, 3, 4, 5, and 6 provided herein. The present invention also provides me... | 11/26/2009 |
| 20090279071 | SPECTROSCOPIC DETECTOR AND METHOD FOR DETERMINING THE PRESENCE OF BLOOD AND BIOLOGICAL MARKER SUBSTANCES IN LIQUIDS The invention relates to a detector for measuring scattered light in liquids having a housing, a transparent, flexible tube for transporting liquid through the housing, a light emitter, and a light detector. Two parallel surfaces are formed in the housing, between which... | 11/12/2009 |
| 20090268194 | BLOOD ANALYSIS APPARATUS AND SETTING METHOD OF MEASUREMENT POSITION IN BLOOD ANALYSIS APPARATUS A blood analysis apparatus is provided. The blood analysis apparatus includes: a chip holding portion having an aperture which allows light to pass therethrough and holding a μ-TAS chip for holding a measurement liquid; a rotary body on which the chip holding portion i... | 10/29/2009 |
| 20090251683 | VIRTUAL SEPARATION OF BOUND AND FREE LABEL IN A LIGAND ASSAY FOR PERFORMING IMMUNOASSAYS OF BIOLOGICAL FLUIDS, INCLUDING WHOLE BLOOD Detection and characterization of immunologically detected substances are performed electronically on human and animal biological fluids such as whole blood, serum, plasma, urine, milk, pleural and peritoneal fluids, and semen, which fluids are contained in a thin chamb... | 10/08/2009 |
| 20090219509 | Optical sensor with enhanced reflectance A device for determination of analytes is disclosed that comprises an optical material having a deposit on a surface thereof, where this deposit includes an analyte-reactive reagent and a particulate means for enhancing reflectance of a light beam emitted through the op... | 09/03/2009 |
| 20090219510 | Nonhemolytic optical sensor with enhanced reflectance A nonhemolytic sensor for determination of analytes in erythrocyte-containing biological fluids is disclosed that comprises an optical material having a deposit on a surface thereof, where this deposit includes an analyte-reactive reagent and a particulate means for sup... | 09/03/2009 |
| 20090213360 | DEVICE AND METHOD FOR IN VITRO DETERMINATION OF ANALYTE CONCENTRATION WITHIN BODY FLUIDS A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-b... | 08/27/2009 |
| 20090204366 | APPARATUS AND METHOD FOR NON-INVASIVE MEASUREMENT OF THE CONCENTRATION OF A SUBSTANCE IN SUBJECT'S BLOOD A method determines the concentration of a substance in a subject's blood. The method includes measuring an interaction of at least one light beam with a portion of the subject's body. The method further includes calculating a value of an optically-measured parameter in... | 08/13/2009 |