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"What, sir, would you make a ship sail against the wind and currents by lighting a bonfire under her deck? I pray you, excuse me, I have not the time to listen to such nonsense."
Napoleon Bonaparte ; When told of the Robert Fulton steamboat
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| Application No. | Application Title | Issue Date |
| 20120129721 | URINARY GM2 ACTIVATOR PROTEIN AS A MARKER OF ACUTE RENAL FAILURE OR THE RISK OF DEVELOPING ACUTE RENAL FAILURE The invention relates to a method of determining the risk of developing acute renal failure (ARF) in an individual, or of determining an ARF, and a method of predicting the progression of an ARF, by detecting and/or quantifying the protein Ganglioside GM2 Activator Prot... | 05/24/2012 |
| 20120103810 | HIGH-SENSITIVITY PROTEOLYSIS ASSAY The present invention includes a highly sensitive method for detecting the presence of proteases in a sample which are present at very low levels.... | 05/03/2012 |
| 20120082989 | USES FOR LONG POLAR FIMBRIAE GENES OF PATHOGENIC ESCHERICHIA COLI STRAINS Provided are methods for identifying lpf genes in pathogenic serotypes of the Enterobacteriaceae family and for differentiating Escherichia coli (E. coli) O157:H7 strains in an isolate using primer pairs specific to lpf gene variants, particularly IpfA1 an... | 04/05/2012 |
| 20120083008 | Methods for obtaining molecules with reduced immunogenicity The invention provides a method for reducing immunogenicity of a peptide, protein or protein complex in an individual comprising introducing at least one cross-link between two amino acids in the peptide, protein or protein complex that is stable or irreversible in vivo... | 04/05/2012 |
| 20120053226 | DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS The invention relates to design of short oligonucleotides and analogs thereof (such as, di-, and trinucleotide compounds) useful for various therapeutic applications. It is believed that the compounds of the invention can be used as antiviral agents, anticancer agents a... | 03/01/2012 |
| 20120052594 | ASSAY FOR DETERMINATION OF LEVELS OF LIPOPROTEIN PARTICLES IN BODILY FLUIDS An assembly, method, system, and apparatus for the assessment of the level of specific lipoprotein particles present in a bodily fluid are disclosed. The levels determined may be used to predict the risk of developing various diseases related to lipoprotein particles.... | 03/01/2012 |
| 20120052593 | ASSAY FOR DETERMINATION OF LEVELS OF LIPOPROTEIN PARTICLE NUMBER IN BODILY FLUIDS An assembly, method, system, and apparatus for the assessment of the level of specific lipoprotein particles present in a bodily fluid are disclosed. The levels determined may be used to predict the risk of developing various diseases related to lipoprotein particles.... | 03/01/2012 |
| 20120034317 | Prediction of Response to Platinum-Based Therapy Method for determining whether a mammalian subject having a cancer belongs to a first or a second group, wherein subjects of the first group are more likely to respond to a platinum-based therapy than subjects of the second group, comprising the steps of: evaluating the... | 02/09/2012 |
| 20120035322 | POLYNUCLEIC ACID-ATTACHED PARTICLES AND THEIR USE IN GENOMIC ANALYSIS Disclosed are methods for preparing particle-linked polynucleotides, and using the particle linked polynucleotides in genomic analysis. The particles as disclosed are characterized as having a size variance of less than 2%.... | 02/09/2012 |
| 20120024702 | CHARGED PARTICLE MOTION INDUCING APPARATUS Apparatus for inducing motion of charged particles in a liquid or gel using an electric field includes a region in which the motion is to be induced, first and second electrodes for generating the electric field in the region whereby a current passes between the electro... | 02/02/2012 |
| 20120024701 | GENERAL PROCEDURE FOR THE IDENTIFICATION OF DNA SEQUENCES GENERATING ELECTROMAGNETIC SIGNALS IN BIOLOGICAL FLUIDS AND TISSUES A general method for producing EMS positive samples or samples containing nanostructures characteristic of self-replicating molecules like DNA by dilution and agitation. Methods of transduction into DNA information or for inducing EMS in an originating sample and transd... | 02/02/2012 |
| 20120027749 | Method The present invention provides a method for detecting a 5T4-positive cancer in a subject, which comprises the following steps: (i) identifying and/or isolating exosomes in a sample from the subject; and (ii) detecting exosome-associated 5T4.... | 02/02/2012 |
| 20120012461 | ELECTROPHORETIC DEPOSITION The present disclosure generally relates to systems, arrangements, and techniques for electrophoretic deposition of a plating material on a surface of a substrate. Example systems may include one or more of a substrate for receiving the plating material, a gel, a source... | 01/19/2012 |
| 20120015357 | PREDICTION OF LIPID-METABOTYPE-RELATED PHYSIOLOGICAL SUSCEPTIBILITIES The present invention relates to a method for determining a predisposition of a human subject for physiological susceptibilities that result from alterations in lipid metabolism, wherein the physiological susceptibilities are selected from sensitivity to functional food... | 01/19/2012 |
| 20120016008 | ISOLATED GENOMIC POLYNUCLEOTIDE FRAGMENTS FROM THE p15 REGION OF CHROMOSOME 11 ENCODING HUMAN RIBOSOMAL PROTEIN L26 (RIBO26) Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human ribosomal protein L26 (RIBO26) and methods of use.... | 01/19/2012 |
| 20120014748 | NOVEL SOIL DIAGNOSIS METHOD Disclosed are a soil diagnosis method for diagnosing soil using a cycle activity indicator which is calculated using the following factors (I) to (III): (I) the ammonia reduction rate in target soil; (II) the activity of forming phosphoric acid from phytic acid in the t... | 01/19/2012 |
| 20120006682 | NUCLEIC ACID CONCENTRATION RECOVERY CARTRIDGE, NUCLEIC ACID CONCENTRATION RECOVERY METHOD, AND FABRICATION PROCESS OF CARTRIDGE A nucleic acid concentration recovery cartridge includes a substrate, a channel with which the substrate is provided to permit introduction of a liquid therein, a high molecular gel arranged in the channel at a predetermined position thereof, and a cathode and anode arr... | 01/12/2012 |
| 20120010268 | ISOLATED GENOMIC POLYNUCLEOTIDE FRAGMENTS FROM THE p15 REGION OF CHROMOSOME 11 ENCODING HUMAN ACHAETE-SCUTE HOMOLOG 2 (HASH2) Provided herein are isolated genomic polynucleotide fragments from the p15 arm of chromosome 11 encoding HASH2 and methods of use.... | 01/12/2012 |
| 20120010269 | ISOLATED GENOMIC POLYNUCLEOTIDE FRAGMENTS FROM THE p15 REGION OF CHROMOSOME 11 ENCODING HUMAN SMS3 Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human SMS3 (SMS3) and methods of use.... | 01/12/2012 |
| 20120010270 | ISOLATED GENOMIC POLYNUCLEOTIDE FRAGMENTS FROM THE p15 REGION OF CHROMOSOME 11 ENCODING HUMAN TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 6 (TSSC6) Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human tumor suppressing subtransferable candidate 6 and methods of use.... | 01/12/2012 |
| 20120004133 | METHOD FOR THE DIAGNOSIS OF AGE-ASSOCIATED VASCULAR DISORDERS Methods for determining if a subject has or is susceptible to having an age-associated vascular disorder are disclosed. The method includes determining if the subject exhibits altered expression of a product of one or more of the genes listed in Table 1 relative to a co... | 01/05/2012 |
| 20120000779 | SURFACE ACOUSTIC WAVE SENSOR DEVICE INCLUDING TARGET BIOMOLECULE ISOLATION COMPONENT Provided herein is a surface acoustic wave (“SAW”) sensor device including an isolation component of a target biomolecule. A sample containing the target biomolecule is separated by its size using electrophoresis, and sequentially reacts with a SAW sensor. In other ... | 01/05/2012 |
| 20110311988 | POLYMER END GROUP DETECTION Provided herein are processes of detecting and quantifying the number of polymer end groups in a sample. In particular instances provided herein are processes of detecting.... | 12/22/2011 |
| 20110306514 | RATIO BASED BIOMARKERS AND METHODS OF USE THEREOF Compositions, methods and kits are described for identifying biomolecules (e.g., proteins and nucleic acids) expressed in a biological sample that are associated with the presence, development, or progression of a disease (such as cancer), or more generally determinatio... | 12/15/2011 |
| 20110301186 | USE OF HAPTOGLOBIN GENOTYPING IN DIAGNOSIS AND TREATMENT OF CARDIOVASCULAR DISEASE This invention is directed to methods and compositions for the treatment of cardiovascular disorders. Specifically, the invention is directed to compositions comprising vitamin E, statins and/or glutathione peroxidase mimetics; methods of treating diabetic patients expr... | 12/08/2011 |
| 20110300641 | PROTEIN ISOFORMS FOR DIAGNOSIS Several aspects of this invention relate to diagnosis of diabetic states in a mammal using protein isoforms. In some aspects, it relates to a method for determining the diabetic state of a mammal. This method can include, for example, (a) measuring the serum concentrati... | 12/08/2011 |
| 20110294148 | TISSUE INHIBITOR OF MATRIX METALLOPROTEINASES TYPE-1 (TIMP-1) AS A CANCER MARKER AND POSTOPERATIVE MARKER FOR MINIMAL RESIDUAL DISEASE OR RECURRENT DISEASE IN PATIENTS WITH A PRIOR HISTORY OF CANCER The present invention describes a method for determining whether an individual is suffering from cancer by determining a parameter representing the TIMP-1 concentration in body fluid samples from the individual. The present invention furthermore describes a method for d... | 12/01/2011 |
| 20110287949 | METHODS FOR DETECTING AND TREATING CANCER The invention generally features compositions and methods for the diagnosis, treatment, and monitoring of neoplasia in a subject, as well as methods of treatment selection.... | 11/24/2011 |
| 20110272282 | SYSTEMS AND METHODS FOR ENHANCED SCODA Methods and apparatus for concentrating particles may be applied, for example, to concentrating DNA, RNA, proteins and the like. Proteins may be pre-treated to facilitate concentration by scodaphoresis. The pre-treatment may comprise, for example, heating or chemical tr... | 11/10/2011 |
| 20110269131 | SUBSTRATE FOR MANUFACTURING DISPOSABLE MICROFLUIDIC DEVICES Embodiments of the present invention relate to a UV-curable polyurethane-methacrylate (PUMA) substrate for manufacturing microfluidic devices. PUMA is optically transparent, biocompatible, and has stable surface properties. Embodiments include two production processes t... | 11/03/2011 |
| 20110269139 | BIOMARKERS AND METHODS FOR DETERMINING SENSITIVITY TO EPIDERMAL GROWTH FACTOR RECEPTOR MODULATORS The present invention provides methods useful for predicting the likelihood that a mammal that will respond therapeutically to a method of treating cancer comprising administering an EGFR modulator, and diagnostic methods and kits thereof.... | 11/03/2011 |
| 20110263437 | Analysis of Y-Chromosome STR Markers The methods and compositions provided herein relate to the discovery of 13 STR are markers found on the human Y chromosome with surprisingly high mutation rates when compared with 173 other Y-STR markers known today, including those that are in common use in forensics. ... | 10/27/2011 |
| 20110262923 | METHOD FOR THE QUANTITATIVE DETERMINATION OF THE NUMBER OF COPIES OF A PREDETERMINED SEQUENCE IN A SAMPLE A method for the quantitative determination of the number of at least one predetermined sequence in a biological sample comprises the steps:
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| 20110263435 | GENETIC MARKERS FOR BOAR TAINT Genetic markers are disclosed with a useful association with boar taint that can be used for screening and selection of pigs for those with more favorable boar taint characteristics associated with androstenone/skatole metabolism. Specific polymorphic alleles of the 3α... | 10/27/2011 |
| 20110263439 | MARKERS ASSOCIATED WITH ALZHEIMER'S DISEASE This application discloses SNPs capable of predicting increased or decreased risk of developing late onset Alzheimer's disease.... | 10/27/2011 |
| 20110256536 | Two stage nucleic acid amplification using an amplification oligomer This invention provides methods, compositions and systems to detect a nucleic acid of interest in a two-stage amplification. The two-stage amplification begins with a first non-enzymatic accumulation of an amplification oligomer that is the target substrate for a second... | 10/20/2011 |
| 20110247935 | ELECTROPHORETIC DEVICE FOR SEPARATION OF CHARGED MOLECULES USING A PETRI DISH The present invention provides a portable circular electrophoretic device having uniform electric field over a small surface area. It also provides a multidirectional process of electrophoresis for separation of charged molecules thereby increasing the resolution of mac... | 10/13/2011 |
| 20110251246 | SMALL MOLECULE INHIBITORS OF MUC1 AND METHODS OF IDENTIFYING THE SAME The invention provides methods for the identification of small molecules that inhibit MUC1 oligomerization, and the functions flowing therefrom. In addition, small molecules that prevent MUC1 oligomerization are disclosed. Identified molecules will find use in treating ... | 10/13/2011 |
| 20110250641 | ZWITTERIONIC ACID-LABILE SURFACTANTS AND METHODS OF USE A compound of the formula: wherein R1 is independently selected from C1-C10 alkyl or substituted alkyl, R2 is independently selected from the group consisting of ... | 10/13/2011 |
| 20110252489 | METHOD OF IDENTIFYING PROLIFICACY IN MAMMALS The present invention refers to a method of predicting prolificacy in mammals, by means of analyzing a specific molecular marker for a novel mutation correlated to the increase of the ovulation rate. The correct and simple identification of the presence of the mutation,... | 10/13/2011 |
