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| Application No. | Application Title | Issue Date |
| 20120125774 | Analysis Chip and Analysis Apparatus An analysis chip that enables an apparatus to be small, analysis to be simple, analysis time to be short and analysis of both glycosylated hemoglobin and glucose to be highly accurate is provided. The electrophoresis chip includes an upper substrate 4, a lower su... | 05/24/2012 |
| 20120125775 | CHEMICAL MODIFICATION OF PROTEINS FOR THEIR MORE ACCURATE MOLECULAR-WEIGHT DETERMINATION BY ELECTROPHORESIS Disclosed herein is a composition and method for sample preparation of proteins for their size separation by electrophoresis, suitable for molecular-weight determination of proteins in the range between about 14,000 and 500,000. In an embodiment, proteins, particularly ... | 05/24/2012 |
| 20120129721 | URINARY GM2 ACTIVATOR PROTEIN AS A MARKER OF ACUTE RENAL FAILURE OR THE RISK OF DEVELOPING ACUTE RENAL FAILURE The invention relates to a method of determining the risk of developing acute renal failure (ARF) in an individual, or of determining an ARF, and a method of predicting the progression of an ARF, by detecting and/or quantifying the protein Ganglioside GM2 Activator Prot... | 05/24/2012 |
| 20120125773 | Analysis Chip and Analysis Apparatus An analysis chip that enables an apparatus to be small, analysis to be simple, analysis time to be short and analysis of both glycosylated hemoglobin and glucose to be highly accurate is provided. The electrophoresis chip includes an upper substrate 4, a lower su... | 05/24/2012 |
| 20120103054 | CALIBRATION METHOD IN MEASUREMENT OF HEMOGLOBIN A1c A calibration method that enables calibration easily in a short time in a measurement of hemoglobin A1c by use of a separation analysis is provided. In a measurement of a hemoglobin A1c amount by use of a separation analysis, a one-point calibration using a single calib... | 05/03/2012 |
| 20120080313 | ELECTROOSMOTIC DEVICES Electroosmotic (EO) devices are provided which are not subject to mechanical wear and tear and with no moving parts, and having improved flow rates and electrical properties. Atomic layer deposition can be used to prepare three electrical terminal active zeta potential ... | 04/05/2012 |
| 20120043207 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE A subject of the present invention is to provide a measurement method using an internal standard substance in an electrophoresis where an analyte is a protein or a compound. The present invention relates to a measurement method for an analyte by an electrophoresis, char... | 02/23/2012 |
| 20120037507 | METHOD AND MARKER FOR DIAGNOSIS OF TUBULAR KIDNEY DAMAGE AND ILLNESSES A method for the diagnosis of tubular kidney diseases comprising the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, the polypeptide marker being selected from the markers characterized in Table 1 by valu... | 02/16/2012 |
| 20120031758 | Nanofabricated Structures for Electric Field-Assisted Nucleic Acid Extraction Embodiments of the invention provide devices and methods for extracting nucleic acid molecules from solution using electric fields. The structures and methods of embodiments of the invention are suited to incorporation into micro and nano fluidic devices, such as lab-on... | 02/09/2012 |
| 20120027749 | Method The present invention provides a method for detecting a 5T4-positive cancer in a subject, which comprises the following steps: (i) identifying and/or isolating exosomes in a sample from the subject; and (ii) detecting exosome-associated 5T4.... | 02/02/2012 |
| 20120028280 | XANTHURENIC ACID DERIVATIVE PHARMACEUTICAL COMPOSITIONS AND METHODS RELATED THERETO The present invention relates to diuretic pharmaceutical compositions and methods and in particular to certain derivatives of the formula I:
| |
| 20120000850 | SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING A method of preparing a sol-gel monolithic column includes the step of forming a separation bed (14) from a sol-gel solution in a single process step. This column has improved characteristics for CEC based on its incorporated surface charge and ease of operation ... | 01/05/2012 |
| 20120000778 | Method for Modifying the Concentration of Reactants in a Microfluidic Device A method of modifying the concentration of reactants and carrying out a chemical reaction on a microfluidic device in which first and second reactants are delivered into a reaction channel combined, the second reactant different from the first reactant and capable of re... | 01/05/2012 |
| 20120000777 | DEVICES AND METHODS FOR FORMING DOUBLE EMULSION DROPLET COMPOSITIONS AND POLYMER PARTICLES The present invention generally relates to double emulsion droplet compositions, polymer particles that can be formed from such double emulsion droplet compositions, and to methods and apparatuses for making such compositions and particles. A double emulsion generally d... | 01/05/2012 |
| 20120004133 | METHOD FOR THE DIAGNOSIS OF AGE-ASSOCIATED VASCULAR DISORDERS Methods for determining if a subject has or is susceptible to having an age-associated vascular disorder are disclosed. The method includes determining if the subject exhibits altered expression of a product of one or more of the genes listed in Table 1 relative to a co... | 01/05/2012 |
| 20110308949 | NANO-FLUIDIC FIELD EFFECTIVE DEVICE TO CONTROL DNA TRANSPORT THROUGH THE SAME The present invention provides a nano-fluidic field effective device. The device includes a channel having a first side and a second side, a first set of electrodes adjacent to the first side, a second set of electrodes adjacent to the second side, a control unit for ap... | 12/22/2011 |
| 20110297543 | Autosomal-Dominant Polycystic Kidney Disease (ADPKD) The process for the diagnosis, early detection and prognosis of the clinical development of autosomal-dominant polycystic kidney disease (ADPKD) comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sampl... | 12/08/2011 |
| 20110297542 | METHOD OF FABRICATION OF MONOLITHIC STATIONARY PHASES FOR SEPARATIONS, AND METHODS OF SEPARATION USING SUCH STATIONARY PHASES Analysis tools for use in analytical separations are provided including a stationary phase comprising an electroconducting material, for example, a conducting polymer. There is further provided a method for manufacturing monolithic stationary phases in various formats i... | 12/08/2011 |
| 20110290648 | Capillary Electrophoresis Device This invention provides a capillary electrophoresis device in which capillaries are thermally regulated on a thermally responsive electrical path attached to an electrically insulating circuit board. This invention also provides an optical scanner useful for scanning an... | 12/01/2011 |
| 20110284375 | Microfluidic device and analyzing device using the same The conventional micropump and the conventional micromixer have the following problems. In a mechanical or hydrodynamic method, the structure of the inside of a flow path is complex so as to easily cause clogging, and manufacturing cost is high, and dead volume is large... | 11/24/2011 |
| 20110281364 | METHOD AND MARKER FOR DIAGNOSING DIABETES MELLITUS A process for the diagnosis of diabetes mellitus comprising the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, the polypeptide markers being selected from the markers characterized by the values for the ... | 11/17/2011 |
| 20110272281 | MICROFLUIDIC DEVICE FOR SEPARATING, FRACTIONATING, OR PRECONCENTRATING ANALYTES CONTAINED IN AN ELECTROLYTE A microfluidic device for separating, fractionating, or preconcentrating analytes contained in an electrolyte having at least two reservoirs separated by at least one microchannel and/or nanochannel. At least part of the wall of the microchannel is made of and/or coated... | 11/10/2011 |
| 20110266151 | Microfluidic systems with electronic wettability switches The present invention concerns microfluidic systems with printed surface structured electronically controllable wettability switches for efficient manipulation of small amounts of fluids. The high performance microfluidic systems of the invention can be used in many app... | 11/03/2011 |
| 20110268822 | METHODS FOR SYNTHESIZING KOTALANOL AND STEREOISOMERS AND ANALOGUES THEREOF, AND NOVEL COMPOUNDS PRODUCED THEREBY Compounds having the general formula (I): wherein X is S, Se or NH, and stereoisomers thereof, and de-O-sulfonated analogues of all of the foregoing, but excluding naturally occurring kotalanol and de-O-sulfonated kotalanol, and methods for synthesizing same. The compou... | 11/03/2011 |
| 20110259742 | Droplet Based Miniaturized Device With On-Demand Droplet-Trapping, -Fusion, And -Releasing The present invention refers to a droplet-based miniaturized device with on-demand droplet-trapping, -fusion, and -releasing. The device makes use of different electrical fields for directing droplets into microwells and releasing them from the same. In another aspect, ... | 10/27/2011 |
| 20110263437 | Analysis of Y-Chromosome STR Markers The methods and compositions provided herein relate to the discovery of 13 STR are markers found on the human Y chromosome with surprisingly high mutation rates when compared with 173 other Y-STR markers known today, including those that are in common use in forensics. ... | 10/27/2011 |
| 20110250641 | ZWITTERIONIC ACID-LABILE SURFACTANTS AND METHODS OF USE A compound of the formula: wherein R1 is independently selected from C1-C10 alkyl or substituted alkyl, R2 is independently selected from the group consisting of â€... | 10/13/2011 |
| 20110245482 | NON-INVASIVE DETECTION OF FETAL GENETIC TRAITS Blood plasma of pregnant women contains fetal and (generally>90%) maternal circulatory extracellular DNA. Most of said fetal DNA contains ≦500 base pairs, said maternal DNA having a greater size. Separation of circulatory extracellular DNA of <500 base pairs res... | 10/06/2011 |
| 20110240471 | EXCHANGEABLE CARRIERS PRE-LOADED WITH REAGENT DEPOTS FOR DIGITAL MICROFLUIDICS The present invention provides exchangeable, reagent pre-loaded carriers (10), preferably in the form of plastic sheets, which can be temporarily applied to an electrode array (16) on a digital microfluidic (DMF) device (14). The carrier (10)... | 10/06/2011 |
| 20110236878 | Rapid Characterization of Proteins in Complex Biological Fluids Disclosed herein are compositions and methods for the rapid screening of candidate protein therapeutics. In particular, the instant invention provides compositions and methods for assaying the behavior of candidate protein therapeutics in complex biological fluids and f... | 09/29/2011 |
| 20110236984 | DNA SEQUENCING METHODS AND DETECTORS AND SYSTEMS FOR CARRYING OUT THE SAME In some embodiments, an analyte detection system is provided that includes a nanochannel, an electrode arrangement, and a plurality of nanoFET devices disposed in the nanochannel. A plurality of nucleic acid base detection components can be used that include a plurality... | 09/29/2011 |
| 20110229872 | Microfabricated Cell Sorter The invention provides a microfabricated device for sorting cells based on a desired characteristic, for example, reporter-labeled cells can be sorted by the presence or level of reporter on the cells. The device includes a chip having a substrate into which is microfab... | 09/22/2011 |
| 20110226621 | TARGET RECOGNITION MOLECULE AND A METHOD FOR IMMOBILIZING THE SAME There is provided a novel target recognition molecule. The target recognition molecule has a specific reactivity, and can be densely self-assembled and immobilized reversibly or irreversibly at a predetermined site in a microfluidic device. And The target recognition mo... | 09/22/2011 |
| 20110220499 | Non-focusing tracers for indirect detection in electrophoretic displacement techniques A novel method for visualizing electrokinetic process zones (e.g., for isotachophoresis (ITP)) is provided. We introduce negligibly small concentrations of a fluorophore that is not focused by isotachophoresis. This non-focusing tracer (NFT) migrates through multiple is... | 09/15/2011 |
| 20110220498 | Method for Building Massively-Parallel Preconcentration Device for Multiplexed, High-Throughput Applications A multiplexed concentration interface that can connect with a plurality of microchannels, conventional 96 well plates or other microarrays is disclosed. The interface can be used in biosensing platforms and can be designed to detect single or multiple targets such as DN... | 09/15/2011 |
| 20110220500 | Glucuronidated Acetaminophen as a Marker of Hepatic Disorders The present invention provides methods for diagnosing human hepatic disorders, such as non-alcoholic steatohepatitis (NASH), identifying a human subject at risk of an adverse drug reaction, and determining an appropriate dosage of a therapeutic drug for a human subject.... | 09/15/2011 |
| 20110223605 | Multiple-sample microfluidic chip for DNA analysis Aspects of the disclosure provide a microfluidic chip. The microfluidic chip includes a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, and a second domain for electrophoretic separation. The first domain includes at least a f... | 09/15/2011 |
| 20110214990 | KIDNEY CELL CARCINOMA The process for the diagnosis of a renal cell carcinoma comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, wherein said polypeptide markers are selected from the markers as characterized in Tab... | 09/08/2011 |
| 20110210000 | Isoelectric particles and uses therefore A plurality of particles of from about 5 nm to 100 μm possessing predetermined isoelectric points in the pH range of from about 2.5 to 11 is used in a method of detection of a plurality of analytes, wherein the isoelectric particles of each isoelectric point further co... | 09/01/2011 |
| 20110212914 | STABILIZED PENTOSAN POLYSULFATE (PPS) FORMULATIONS AND METHODS OF ANALYZING THEM Various pentosan polysulfate (PPS) formulations useful for treatment of osteoarthritis, interstitial cystitis, and other conditions of mammals are provided. These formulations showed improved resistance to degradation and discoloration and improved stability at physiolo... | 09/01/2011 |
