"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 8178089 | Neuronal progenitors from feeder-free human embryonic stem cell culture The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder cell-free neuroprogenitor cells, preferably human cells themselves, as w... | 05/15/2012 |
| 8168657 | Solenopsin A, B and analogs and as novel angiogenesis inhibitors The present invention relates to solenopsin A and its analogs for use as angiogenesis inhibitors. The present compounds unexpectedly exhibit good activity as angiogenesis inhibitors, which find use as antitumor/anticancer agents as well as to treat a number of condi... | 05/01/2012 |
| 8168632 | Bicyclic amide derivatives for the treatment of respiratory disorders This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of disorders of respiration such as overdose of an alcohol, an opiate, an opioid, a barbiturate, an anesthetic, or a nerve toxin. In a particular asp... | 05/01/2012 |
| 8157725 | Port extraction kit for trans-organ surgery A surgical method for removing a port element disposed in an incision or perforation in a wall of a hollow internal organ in a trans-organ surgical procedure. A distal end portion of a tubular member is inserted into the internal organ through a natural body opening... | 04/17/2012 |
| D657146 | Picture frame | 04/10/2012 |
| D656744 | Picture frame | 04/03/2012 |
| 8119632 | Bicyclic amide derivatives for enhancing glutamatergic synaptic responses This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behavio... | 02/21/2012 |
| 8114987 | Preparation method of 2-deoxy-L-ribose A method of preparing 2-deoxy-L-ribose represented by the following formula I is disclosed. The preparation method includes the steps of: treating L-arabinose with an alcohol solvent in the presence of an acid to prepare 1-alkoxy-L-arabinopyranose; allowing the prep... | 02/14/2012 |
| 8110584 | Methods for the treatment of respiratory depression This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behavio... | 02/07/2012 |
| 8109925 | Treatment of breast disease with vibrating device An elongate probe, with a suction channel extending longitudinally along the probe, is inserted into a patient so that a distal tip of the probe is in contact with a fibroid mass inside the patient. Thereafter the probe is ultrasonically vibrated so that the distal ... | 02/07/2012 |
| 8101714 | Teleost derived antimicrobial polypeptides The invention is directed to an isolated polypeptide which (a) is obtainable from a teleost; (b) has antimicrobial activity; (c) binds to oligoguanosine and/or CpG (SEQ ID NO:7); (d) comprises 58 strongly basic amino acids selected from the group consisting of K and... | 01/24/2012 |
| 8101213 | Xanthohumol compositions and methods of using same The present invention provides compositions comprising an effective amount of xanthohumol and honokiol. The present invention comprises compositions comprising an effective amount of xanthohumol and genistein. The present invention comprises compositions comprising ... | 01/24/2012 |
| 8097237 | Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present invention represents a clear advance in the art which presently relies on tis... | 01/17/2012 |
| 8097001 | Medical instrument with stop motion override and associated method A medical instrument comprises a tubular introducer member, an operative element, an elongate shifter connected at a distal end to the operative element, a handle, at least one stop component, and an override. The shifter and the operative element are movable relati... | 01/17/2012 |
| 8084641 | Organocataslysts and methods of use in chemical synthesis The present invention is directed to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-selective ... | 12/27/2011 |
| 8084471 | Proteomimetic compounds as inhibitors of the interaction of nuclear receptor with coactivator peptides The present invention relates to compounds, pharmaceutical compositions and methods which inhibit the binding of coactivator proteins in nuclear receptors, including estrogen receptors (alpha and/or beta), androgen receptors, thyroid receptors and peroxisome prolife... | 12/27/2011 |
| D651274 | Shotgun | 12/27/2011 |
| 8080752 | Control assembly for interlocked sockets A control assembly for interlocked sockets includes a rotary breaker which is actuated by a knob and is mounted on a supporting structure. The control assembly includes a visual indication means which has the purpose of highlighting the open/closed state of the rota... | 12/20/2011 |
| 8076347 | Compounds and methods for the treatment of cancer (−)-(2S,4S)-1-(2-Hydroxymethyl-1,3-dioxolan-4-yl)cytosine (also referred to as (−)-OddC) or its derivative and its use to treat cancer in animals, including humans. ... | 12/13/2011 |
| 8058266 | Methods and compositions for treatment of macular and retinal disease The present invention describes linking a therapeutic agent to a compound which is known to be naturally concentrated in a tissue affected by, or that is causing, a disease, to create a prodrug for treatment of the disease. Embodiments of the present invention inclu... | 11/15/2011 |
| 8025672 | Ultrasonic wound treatment method and apparatus A surgical device includes a probe, a transducer assembly operatively coupled to the probe for generating an ultrasonic resonant vibration therein, and a frequency generator operatively coupled to the transducer assembly for energizing the transducer component. A co... | 09/27/2011 |
| 8021872 | Flow cytometry for high throughput screening The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means... | 09/20/2011 |
| 8016839 | Intra-abdominal medical procedures and device Improvements in intra-abdominal surgery include a method for removing large chunks of organic or inorganic material from the abdomen through a natural body opening such as the urethra. The technique may be supplemented by laparoscopic procedures. ... | 09/13/2011 |
| 8013120 | C-reactive protein and its use to treat systemic lupus erythematosus and related conditions The present invention relates to the use of C-reactive protein, its mutants, metabolites and polypeptides and related compounds thereof for the treatment of various disease states and conditions associated with systemic lupus erythematosus (SLE), including lupus of ... | 09/06/2011 |
| 8013003 | Di-substituted amides for enhancing glutamatergic synaptic responses This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behavio... | 09/06/2011 |
| D644326 | Ultrasonic wound treatment probe | 08/30/2011 |
| D643625 | Case | 08/23/2011 |
| 7974719 | Method and an apparatus for automatic manufacture of an object with multiple intersecting components Systems and methods for the automatic manufacture of a multiple component object with intersecting components based on a standard design model of the object. The systems and methods according to the invention are capable of automatically extracting from a design mod... | 07/05/2011 |
| 7968734 | Organocatalysts and methods of use in chemical synthesis The present invention pertains generally to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-sel... | 06/28/2011 |
| 7951788 | Method of treating cancer and other conditions or disease states using L-cytosine nucleoside analogs The present invention relates to the use of the compound according to formula (I) Where S is (A) or (B); X is H or F; R1 is H, an acyl group, a C1-C20 alkyl or ether group, a phosphate, diphosphate, triphosphate or a phosphodiester g... | 05/31/2011 |
| 6811475 | Surface finishing pad Disclosed is a surface finishing pad for fitting to a base plate of a surface-finishing machine. The Surface finishing pad includes a retaining disc for attachment to the base plate. The retaining disc contains engaging means for engaging a mounting pad onto which o... | 11/02/2004 |
| 7531354 | Neuronal progenitors from feeder-free human embryonic stem cell culture The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder cell-free neuroprogenitor cells, preferably human cells themselves, as w... | 05/12/2009 |
| 7521568 | Enantiopure 4-deoxypentenosides, dihydropyrans and tetrahydropyrans and syntheses thereof Enantiopure substituted 4-deoxypentenosides (4-DPs) and related dihydropyrans (DHPs) are prepared from common carbohydrates via a novel process. The 4-DPs and related DHPs are amenable to a broad range of stereoselective transformations and are used as synthetic int... | 04/21/2009 |
| 7501535 | Chemical synthons and intermediates The invention provides novel six and seven-carbon termini-differentiated polypropionate stereotetrads and stereopentads useful in syntheses of natural products. The invention also provides a novel alkylative sulfenylation-desulfonylation process that efficiently tra... | 03/10/2009 |
| 7500956 | Apparatus and method for resonant destruction of tumors In a method for treating cancer, a series of investigatory pressure waves of respective different preselected frequencies are generated in a patient so that the pressure waves are transmitted to a tumor through overlying tissues, while responsive oscillatory motion ... | 03/10/2009 |
| 7497828 | Ultrasonic medical device and associated method A medical system includes a carrier and a multiplicity of electromechanical transducers mounted to the carrier, the transducers being disposable in effective pressure-wave-transmitting contact with a patient. Energization componentry is operatively connected to a fi... | 03/03/2009 |
| 7497669 | Wesco type fuel pump To make a Wesco type fuel pump to supply pressure-increased fuel toward a fuel injection valve with no time delay at a time of restarting an engine, an impeller (8) which is rotated by an electric motor (M) arranged within a motor chamber (9) is arrang... | 03/03/2009 |
| D587589 | Bottle | 03/03/2009 |
| 7472808 | Powder and granular material metering device A powder body metering apparatus for metering a powder body such as a synthetic resin raw material is structured such that a powder body outlet of a metering container of another metering apparatus is connected to a second opening (50), whereby a powder body ... | 01/06/2009 |
| D537725 | Bottle | 03/06/2007 |