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Attorney: sudol; R. Neil


Number of patents: 40
Last date: May 15, 2012

NumberTitleIssue Date
8178089Neuronal progenitors from feeder-free human embryonic stem cell culture
The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder cell-free neuroprogenitor cells, preferably human cells themselves, as w...
05/15/2012
8168657Solenopsin A, B and analogs and as novel angiogenesis inhibitors
The present invention relates to solenopsin A and its analogs for use as angiogenesis inhibitors. The present compounds unexpectedly exhibit good activity as angiogenesis inhibitors, which find use as antitumor/anticancer agents as well as to treat a number of condi...
05/01/2012
8168632Bicyclic amide derivatives for the treatment of respiratory disorders
This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of disorders of respiration such as overdose of an alcohol, an opiate, an opioid, a barbiturate, an anesthetic, or a nerve toxin. In a particular asp...
05/01/2012
8157725Port extraction kit for trans-organ surgery
A surgical method for removing a port element disposed in an incision or perforation in a wall of a hollow internal organ in a trans-organ surgical procedure. A distal end portion of a tubular member is inserted into the internal organ through a natural body opening...
04/17/2012
D657146Picture frame
04/10/2012
D656744Picture frame
04/03/2012
8119632Bicyclic amide derivatives for enhancing glutamatergic synaptic responses
This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behavio...
02/21/2012
8114987Preparation method of 2-deoxy-L-ribose
A method of preparing 2-deoxy-L-ribose represented by the following formula I is disclosed. The preparation method includes the steps of: treating L-arabinose with an alcohol solvent in the presence of an acid to prepare 1-alkoxy-L-arabinopyranose; allowing the prep...
02/14/2012
8110584Methods for the treatment of respiratory depression
This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behavio...
02/07/2012
8109925Treatment of breast disease with vibrating device
An elongate probe, with a suction channel extending longitudinally along the probe, is inserted into a patient so that a distal tip of the probe is in contact with a fibroid mass inside the patient. Thereafter the probe is ultrasonically vibrated so that the distal ...
02/07/2012
8101714Teleost derived antimicrobial polypeptides
The invention is directed to an isolated polypeptide which (a) is obtainable from a teleost; (b) has antimicrobial activity; (c) binds to oligoguanosine and/or CpG (SEQ ID NO:7); (d) comprises 58 strongly basic amino acids selected from the group consisting of K and...
01/24/2012
8101213Xanthohumol compositions and methods of using same
The present invention provides compositions comprising an effective amount of xanthohumol and honokiol. The present invention comprises compositions comprising an effective amount of xanthohumol and genistein. The present invention comprises compositions comprising ...
01/24/2012
8097237Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present invention represents a clear advance in the art which presently relies on tis...
01/17/2012
8097001Medical instrument with stop motion override and associated method
A medical instrument comprises a tubular introducer member, an operative element, an elongate shifter connected at a distal end to the operative element, a handle, at least one stop component, and an override. The shifter and the operative element are movable relati...
01/17/2012
8084641Organocataslysts and methods of use in chemical synthesis
The present invention is directed to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-selective ...
12/27/2011
8084471Proteomimetic compounds as inhibitors of the interaction of nuclear receptor with coactivator peptides
The present invention relates to compounds, pharmaceutical compositions and methods which inhibit the binding of coactivator proteins in nuclear receptors, including estrogen receptors (alpha and/or beta), androgen receptors, thyroid receptors and peroxisome prolife...
12/27/2011
D651274Shotgun
12/27/2011
8080752Control assembly for interlocked sockets
A control assembly for interlocked sockets includes a rotary breaker which is actuated by a knob and is mounted on a supporting structure. The control assembly includes a visual indication means which has the purpose of highlighting the open/closed state of the rota...
12/20/2011
8076347Compounds and methods for the treatment of cancer
(−)-(2S,4S)-1-(2-Hydroxymethyl-1,3-dioxolan-4-yl)cytosine (also referred to as (−)-OddC) or its derivative and its use to treat cancer in animals, including humans. ...
12/13/2011
8058266Methods and compositions for treatment of macular and retinal disease
The present invention describes linking a therapeutic agent to a compound which is known to be naturally concentrated in a tissue affected by, or that is causing, a disease, to create a prodrug for treatment of the disease. Embodiments of the present invention inclu...
11/15/2011
8025672Ultrasonic wound treatment method and apparatus
A surgical device includes a probe, a transducer assembly operatively coupled to the probe for generating an ultrasonic resonant vibration therein, and a frequency generator operatively coupled to the transducer assembly for energizing the transducer component. A co...
09/27/2011
8021872Flow cytometry for high throughput screening
The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means...
09/20/2011
8016839Intra-abdominal medical procedures and device
Improvements in intra-abdominal surgery include a method for removing large chunks of organic or inorganic material from the abdomen through a natural body opening such as the urethra. The technique may be supplemented by laparoscopic procedures. ...
09/13/2011
8013120C-reactive protein and its use to treat systemic lupus erythematosus and related conditions
The present invention relates to the use of C-reactive protein, its mutants, metabolites and polypeptides and related compounds thereof for the treatment of various disease states and conditions associated with systemic lupus erythematosus (SLE), including lupus of ...
09/06/2011
8013003Di-substituted amides for enhancing glutamatergic synaptic responses
This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behavio...
09/06/2011
D644326Ultrasonic wound treatment probe
08/30/2011
D643625Case
08/23/2011
7974719Method and an apparatus for automatic manufacture of an object with multiple intersecting components
Systems and methods for the automatic manufacture of a multiple component object with intersecting components based on a standard design model of the object. The systems and methods according to the invention are capable of automatically extracting from a design mod...
07/05/2011
7968734Organocatalysts and methods of use in chemical synthesis
The present invention pertains generally to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-sel...
06/28/2011
7951788Method of treating cancer and other conditions or disease states using L-cytosine nucleoside analogs
The present invention relates to the use of the compound according to formula (I) Where S is (A) or (B); X is H or F; R1 is H, an acyl group, a C1-C20 alkyl or ether group, a phosphate, diphosphate, triphosphate or a phosphodiester g...
05/31/2011
6811475Surface finishing pad
Disclosed is a surface finishing pad for fitting to a base plate of a surface-finishing machine. The Surface finishing pad includes a retaining disc for attachment to the base plate. The retaining disc contains engaging means for engaging a mounting pad onto which o...
11/02/2004
7531354Neuronal progenitors from feeder-free human embryonic stem cell culture
The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder cell-free neuroprogenitor cells, preferably human cells themselves, as w...
05/12/2009
7521568Enantiopure 4-deoxypentenosides, dihydropyrans and tetrahydropyrans and syntheses thereof
Enantiopure substituted 4-deoxypentenosides (4-DPs) and related dihydropyrans (DHPs) are prepared from common carbohydrates via a novel process. The 4-DPs and related DHPs are amenable to a broad range of stereoselective transformations and are used as synthetic int...
04/21/2009
7501535Chemical synthons and intermediates
The invention provides novel six and seven-carbon termini-differentiated polypropionate stereotetrads and stereopentads useful in syntheses of natural products. The invention also provides a novel alkylative sulfenylation-desulfonylation process that efficiently tra...
03/10/2009
7500956Apparatus and method for resonant destruction of tumors
In a method for treating cancer, a series of investigatory pressure waves of respective different preselected frequencies are generated in a patient so that the pressure waves are transmitted to a tumor through overlying tissues, while responsive oscillatory motion ...
03/10/2009
7497828Ultrasonic medical device and associated method
A medical system includes a carrier and a multiplicity of electromechanical transducers mounted to the carrier, the transducers being disposable in effective pressure-wave-transmitting contact with a patient. Energization componentry is operatively connected to a fi...
03/03/2009
7497669Wesco type fuel pump
To make a Wesco type fuel pump to supply pressure-increased fuel toward a fuel injection valve with no time delay at a time of restarting an engine, an impeller (8) which is rotated by an electric motor (M) arranged within a motor chamber (9) is arrang...
03/03/2009
D587589Bottle
03/03/2009
7472808Powder and granular material metering device
A powder body metering apparatus for metering a powder body such as a synthetic resin raw material is structured such that a powder body outlet of a metering container of another metering apparatus is connected to a second opening (50), whereby a powder body ...
01/06/2009
D537725Bottle
03/06/2007
 
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