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| Number | Title | Issue Date |
| 8101645 | Thienopyrroles and pyrrolothiazoles as new therapeutic agents The present invention is directed to novel compounds of Formula (I) wherein the variables are defined as herein. The compounds of Formula (I) are useful as CRTH2 antagonists and as such would be useful in treating certain c... | 01/24/2012 |
| 7956195 | Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates The present invention discloses processes for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates. ... | 06/07/2011 |
| 7863444 | 4-aminopyrrolopyrimidines as kinase inhibitors Chemical compounds having structural formula I and physiologically acceptable salts thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the kinases whose activity is inhibited by these compo... | 01/04/2011 |
| 7795494 | Transgenic mice expressing antibodies specific for genes of interest and uses thereof The invention provides compositions and methods for the generation of novel non-human transgenic animals which contain an alteration in a gene of interest. These transgenic animals are capable of generating antibodies, e.g., human monoclonal antibodies, specific for... | 09/14/2010 |
| 7491516 | Dual specificity antibodies and methods of making and using Antibodies having dual specificity for two different but structurally related antigens are provided. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have dual specificity for IL-1Î... | 02/17/2009 |
| 7369946 | Method of identifying inhibitors of Tie-2 The present invention relates to polypeptides which comprise the ligand binding domain of Tie-2, crystalline forms of these polypeptides and the use of these crystalline forms to determine the three dimensional structure of the catalytic domain of Tie-2. The inventi... | 05/06/2008 |
| 7332497 | Pyrazolopyrimidines as therapeutic agents The present invention provides compounds of Formula I, including pharmaceutically acceptable salts and/or prodrugs thereof, where G, Ra, R2, and R3 are defined as described herein... | 02/19/2008 |
| 6238860 | Binding moieties for human parvovirus B19 Methods for detecting human parvovirus B19 in and removing it from biological samples such as blood are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human parvovirus B19 and/or B19-like polypeptide ... | 05/29/2001 |
