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...that when IBM conducted a market study of Chester Carlson's invention in 1959, the company concluded that it would take only 5000 units of his new product to saturate the market? IBM therefore declined to be part of the new product introduction. Too bad for IBM. Carlson's invention was the xerography process, and his new product was the beginning of the Xerox Corporation. It is estimated that every day, worldwide, 3,000,000,000 copies are made!!

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Attorney: Yasger; Paul D.


Number of patents: 29
Last date: March 29, 2011

NumberTitleIssue Date
7914999Non-denaturing lysis reagent
The invention provides a lysis reagent and method for preparing a test sample for use in an assay, wherein the method yields a homogeneous lysis mixture suitable for use in automated pipetting systems without the need for a centrifugation step. The lysis reagent inc...
03/29/2011
7776605Assay for cardiac troponin autoantibodies
The invention provides among other things methods and kits based on assaying for cardiac troponin autoantibodies, either in conjunction with an assay for cardiac troponin and/or as an independent indicator of cardiac pathology, such as myocarditis, cardiomyopathy, a...
08/17/2010
7517876Anti-infective agents
Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermedia...
04/14/2009
6827208Packaging system for separately storing and dispensing together separate medication components
The present invention relates to a packaging system intended to simplify the usage of multiple medications stored separately and used together, thereby minimize the non-compliant use of the multiple medications. Generally, the separate medication components are cont...
12/07/2004
6720004Controlled release formulation of divalproex sodium
A new oral polymeric controlled release formulation suitable for the once-a-day administration of valproate compounds, such as divalproex sodium, has been discovered. This formulation exhibits significant advantages over the sustained release valproate formulations ...
04/13/2004
6713086Controlled release formulation of divalproex sodium
A new oral polymeric controlled release formulation suitable for the once-a-day administration of valproate compounds, such as divalproex sodium, has been discovered. This formulation exhibits significant advantages over the sustained release valproate formulations ...
03/30/2004
6528091Controlled release formulation of divalproex sodium
A controlled release tablet formulation which permits once daily dosing in the treatment of epilepsy comprises from about 50 weight percent to about 55 weight percent of an active ingredient selected from the group consisting of valproic acid, a pharmaceu...
03/04/2003
6528090Controlled release formulation of divalproex sodium
A new oral polymeric controlled release formulation suitable for the once-a-day administration of valproate compounds, such as divalproex sodium, has been discovered. This formulation exhibits significant advantages over the sustained release valproate fo...
03/04/2003
6521790Alkynyl amides and their therapeutic applications
Compounds of formula (I) ##STR1## are novel and useful for treating seizure, migraine and psychiatric disorders....
02/18/2003
6511678Controlled release formulation of divalproex sodium
A new oral polymeric controlled release formulation suitable for the once-a-day administration of valproate compounds, such as divalproex sodium, has been discovered. This formulation exhibits significant advantages over the sustained release valproate fo...
01/28/2003
6294326Analyte detection process using dual labeled probes
Provided herein is a method for detecting the presence of a target nucleic acid sequence in a sample. The present method uses a combination of dual labeled probes and heterogeneous detection methods....
09/25/2001
6232455Nucleic acid primers and probes for detecting HIV-1 and HIV-2
Provided herein are primer/probe sets useful for detecting HIV (i.e. either or both HIV 1 or HIV 2) in a test sample. The primer/probe sets are can be employed according to nucleic acid amplification procedures including PCR or RT PCR. The primer/probe se...
05/15/2001
6210876Nucleic acid primers and probes for detecting Chlamydia pneumoniae
Nucleic acid sequences that are useful for detecting Chlamydia pneumoniae are herein provided. These sequences can be used in hybridization assays or amplification based assays designed to detect the presence of Chlamydia pneumoniae in a test sample. Addi...
04/03/2001
6210898Method of performing immunochromatography
The invention relates to multiplex ligase chain reaction (LCR). Two or more putative target sequences are selected. For each one, a set of four probes is used simultaneously to amplify the putative sequence if it is present in the sample. Preferably, all ...
04/03/2001
6203992Nucleic acid primers and probes for detecting tumor cells
Nucleic acid sequences are provided that are useful as amplification primers and hybridization probes for detecting CK19 target sequence in a test sample. The primers and probes can be employed in amplification based methods for detecting the presence of ...
03/20/2001
6100099Test strip having a diagonal array of capture spots
The invention relates to multiplex ligase chain reaction (LCR). Two or more putative target sequences are selected. For each one, a set of four probes is used simultaneously to amplify the putative sequence if it is present in the sample. Preferably, all ...
08/08/2000
6071480Method for generating a standing sonic wave, methods of sonication with a standing sonic wave, and a standing sonic wave sonicator
The present invention provides a standing sonic wave sonicator, methods of generating a standing sonic wave and a method of sonication which employs a standing sonic wave to disrupt particulate material....
06/06/2000
6068978Apparatus and method for transfer of a fluid sample
Methods, devices, apparatus and kits for amplifying and detecting nucleic acid are provided. The apparatus is a one or two-tier thermal cycling device that operates in conjunction with a reaction/detection unit. A sample is loaded into a reaction chamber ...
05/30/2000
6010857Detection of cervical chlamydia trachomatis infection
The present invention provides methods for detecting Chlamydia trachomatis infections using a female urine sample....
01/04/2000
5998593Fluorescent enzyme substrates
Fluorescent enzyme substrates are provided. The substrates are derivatives of coumarin having an enzyme cleavable group at position 7 and a hydrophilic amide group at position 4. The compounds are highly water soluble, stable at ambient and reduced temper...
12/07/1999
5976824Method and apparatus for collecting a cell sample from a liquid specimen
A method and apparatus for collecting a binding member of interest from a liquid specimen utilizes a collection receptacle in which the specimen is deposited, with an affinity-filter media being place in communication with a discharge port in the collecti...
11/02/1999
5968739Nucleic acid primers and probes for detecting Legionella pneumophila
Nucleic acid sequences that are useful for detecting Legionella pneumophila are herein provided. These sequences can be used in hybridization assays or amplification based assays designed to detect the presence of Legionella pneumophila in a test sample. ...
10/19/1999
5962665Nucleic acid primers and probes for detecting HIV-1 and HIV-2
Provided herein are primer/probe sets useful for detecting HIV (i.e. either or both HIV 1 or HIV 2) in a test sample. The primer/probe sets are can be employed according to nucleic acid amplification procedures including PCR or RT PCR. The primer/probe se...
10/05/1999
5955268Method and reagent for detecting multiple nucleic acid sequences in a test sample
Provided herein are methods for detecting multiple target nucleic acid sequences in a test sample. Also provided is a hybridization platform useful for detecting multiple target sequences in a test sample. The hybridization platform comprises a solid supp...
09/21/1999
5858732Wide dynamic range nucleic acid detection using an aggregate primer series
The present invention provides a method of detecting the amount of a target sequence which may be present in a test sample. The method uses an aggregate primer series, which comprises at least two primer sets, in an amplification reaction to detect the re...
01/12/1999
5846785Oligonucleotides specific for the MOMP gene sequence and methods for the detection of Chlamydia trachomatis
The present invention relates to oligonucleotide probes useful in detecting, e.g. by hybridization or the ligase chain reaction, Chlamydia trachomatis DNA in the presence of other related DNA. The present invention is also directed to methods of detecting...
12/08/1998
5817798Rapid RNA isolation procedure in the presence of a transition metal ion
Provided herein is a rapid method for isolating total RNA from test samples and further for isolating mRNA from test samples....
10/06/1998
5817463Nucleic acid primers and probes for detecting Mycoplasma pneumoniae
Nucleic acid sequences that are useful for detecting Mycoplasma pneumoniae are herein provided. These sequences can be used in hybridization assays or amplification based assays designed to detect the presence of Mycoplasma pneumoniae in a test sample. Ad...
10/06/1998
5616505Haptens tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids
Novel tethered hapten intermediates and related conjugates based on 3-phenyl-1-adamantaneacetic acid, as well as methods for making and using such conjugates. Haptens based on the above core structure may be substituted at any position on the phenyl ring,...
04/01/1997
 
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